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UniProtKB - Q9D780 (SLAF9_MOUSE)
Protein
SLAM family member 9
Gene
Slamf9
Organism
Mus musculus (Mouse)
Status
Functioni
May play a role in the immune response.
By similarityGO - Biological processi
- defense response to bacterium Source: MGI
- plasmacytoid dendritic cell chemotaxis Source: MGI
- plasmacytoid dendritic cell differentiation Source: MGI
- T cell activation Source: GO_Central
Names & Taxonomyi
Protein namesi | Recommended name: SLAM family member 9 |
Gene namesi | Name:Slamf9 |
Organismi | Mus musculus (Mouse) |
Taxonomic identifieri | 10090 [NCBI] |
Taxonomic lineagei | Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Glires › Rodentia › Myomorpha › Muroidea › Muridae › Murinae › Mus › Mus |
Proteomesi |
|
Organism-specific databases
MGIi | MGI:1923692, Slamf9 |
Subcellular locationi
Other locations
Plasma Membrane
- external side of plasma membrane Source: GO_Central
Other locations
- cell surface Source: MGI
- integral component of membrane Source: UniProtKB-KW
Topology
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Topological domaini | 18 – 232 | ExtracellularSequence analysisAdd BLAST | 215 | |
Transmembranei | 233 – 253 | HelicalSequence analysisAdd BLAST | 21 | |
Topological domaini | 254 – 285 | CytoplasmicSequence analysisAdd BLAST | 32 |
Keywords - Cellular componenti
MembranePTM / Processingi
Molecule processing
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Signal peptidei | 1 – 17 | Sequence analysisAdd BLAST | 17 | |
ChainiPRO_0000042234 | 18 – 285 | SLAM family member 9Add BLAST | 268 |
Amino acid modifications
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Glycosylationi | 37 | N-linked (GlcNAc...) asparagineSequence analysis | 1 | |
Glycosylationi | 97 | N-linked (GlcNAc...) asparagineSequence analysis | 1 | |
Glycosylationi | 141 | N-linked (GlcNAc...) asparagineSequence analysis | 1 | |
Glycosylationi | 149 | N-linked (GlcNAc...) asparagineSequence analysis | 1 | |
Disulfide bondi | 154 ↔ 198 | PROSITE-ProRule annotation | ||
Glycosylationi | 175 | N-linked (GlcNAc...) asparagineSequence analysis | 1 | |
Glycosylationi | 206 | N-linked (GlcNAc...) asparagineSequence analysis | 1 |
Keywords - PTMi
Disulfide bond, GlycoproteinProteomic databases
PaxDbi | Q9D780 |
PRIDEi | Q9D780 |
ProteomicsDBi | 261416 |
PTM databases
GlyGeni | Q9D780, 6 sites |
Interactioni
Protein-protein interaction databases
STRINGi | 10090.ENSMUSP00000027830 |
Miscellaneous databases
RNActi | Q9D780, protein |
Family & Domainsi
Domains and Repeats
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Domaini | 25 – 126 | Ig-like V-typeAdd BLAST | 102 | |
Domaini | 134 – 213 | Ig-like C2-typeAdd BLAST | 80 |
Keywords - Domaini
Immunoglobulin domain, Signal, Transmembrane, Transmembrane helixPhylogenomic databases
eggNOGi | ENOG502SB7W, Eukaryota |
InParanoidi | Q9D780 |
OrthoDBi | 990343at2759 |
PhylomeDBi | Q9D780 |
TreeFami | TF334964 |
Family and domain databases
Gene3Di | 2.60.40.10, 2 hits |
InterProi | View protein in InterPro IPR007110, Ig-like_dom IPR036179, Ig-like_dom_sf IPR013783, Ig-like_fold IPR003599, Ig_sub IPR013106, Ig_V-set |
Pfami | View protein in Pfam PF07686, V-set, 1 hit |
SMARTi | View protein in SMART SM00409, IG, 1 hit |
SUPFAMi | SSF48726, SSF48726, 2 hits |
PROSITEi | View protein in PROSITE PS50835, IG_LIKE, 1 hit |
(1+)i Sequence
Sequence statusi: Complete.
: The displayed sequence is further processed into a mature form. Sequence processingi
This entry has 1 described isoform and 1 potential isoform that is computationally mapped.Show allAlign All
Q9D780-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MGALLWSLLL LLQEAKGFSG DDEDPEEVIG VLQESINLSL EIPSNEEIKH
60 70 80 90 100
IDWLFQNNIA IVKPGKKGQP AVIMAVDPRY RGRVSISESS YSLHISNLTW
110 120 130 140 150
EDSGLYNAQV NLKTSESHIT KSYHLRVYRR LSKPHITVNS NISEEGVCNI
160 170 180 190 200
SLTCSIERAG MDVTYIWLSS QDSTNTSHEG SVLSTSWRPG DKAPSYTCRV
210 220 230 240 250
SNPVSNISSR RISVGSFCAD PGYPEKPSML CLLVKSLFLL LLLAILTVGL
260 270 280
CLFRAQKSYE TPRVRKLKRN RIKLRKKGKS GPTPV
Computationally mapped potential isoform sequencesi
There is 1 potential isoform mapped to this entry.BLASTAlignShow allAdd to basketA0A0R4J072 | A0A0R4J072_MOUSE | SLAM family member 9 | Slamf9 | 285 | Annotation score: |
Experimental Info
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Sequence conflicti | 29 | I → V in BAB26328 (PubMed:16141072).Curated | 1 | |
Sequence conflicti | 74 | M → T in AAH19477 (PubMed:15489334).Curated | 1 | |
Sequence conflicti | 204 | V → I in BAB26328 (PubMed:16141072).Curated | 1 | |
Sequence conflicti | 210 | R → H in BAC41061 (PubMed:16141072).Curated | 1 | |
Sequence conflicti | 224 | P → L in BAB26328 (PubMed:16141072).Curated | 1 | |
Sequence conflicti | 263 | R → W in BAC41061 (PubMed:16141072).Curated | 1 | |
Sequence conflicti | 280 | S → P in AAH19477 (PubMed:15489334).Curated | 1 |
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AK009505 mRNA Translation: BAB26328.1 AK090041 mRNA Translation: BAC41061.1 BC019477 mRNA Translation: AAH19477.1 |
CCDSi | CCDS15514.1 |
RefSeqi | NP_083888.3, NM_029612.4 XP_017168527.1, XM_017313038.1 |
Genome annotation databases
GeneIDi | 98365 |
KEGGi | mmu:98365 |
UCSCi | uc007dql.2, mouse |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AK009505 mRNA Translation: BAB26328.1 AK090041 mRNA Translation: BAC41061.1 BC019477 mRNA Translation: AAH19477.1 |
CCDSi | CCDS15514.1 |
RefSeqi | NP_083888.3, NM_029612.4 XP_017168527.1, XM_017313038.1 |
3D structure databases
AlphaFoldDBi | Q9D780 |
SMRi | Q9D780 |
ModBasei | Search... |
Protein-protein interaction databases
STRINGi | 10090.ENSMUSP00000027830 |
PTM databases
GlyGeni | Q9D780, 6 sites |
Proteomic databases
PaxDbi | Q9D780 |
PRIDEi | Q9D780 |
ProteomicsDBi | 261416 |
Protocols and materials databases
ABCDi | Q9D780, 22 sequenced antibodies |
DNASUi | 98365 |
Genome annotation databases
GeneIDi | 98365 |
KEGGi | mmu:98365 |
UCSCi | uc007dql.2, mouse |
Organism-specific databases
CTDi | 89886 |
MGIi | MGI:1923692, Slamf9 |
Phylogenomic databases
eggNOGi | ENOG502SB7W, Eukaryota |
InParanoidi | Q9D780 |
OrthoDBi | 990343at2759 |
PhylomeDBi | Q9D780 |
TreeFami | TF334964 |
Miscellaneous databases
BioGRID-ORCSi | 98365, 1 hit in 73 CRISPR screens |
PROi | PR:Q9D780 |
RNActi | Q9D780, protein |
SOURCEi | Search... |
Family and domain databases
Gene3Di | 2.60.40.10, 2 hits |
InterProi | View protein in InterPro IPR007110, Ig-like_dom IPR036179, Ig-like_dom_sf IPR013783, Ig-like_fold IPR003599, Ig_sub IPR013106, Ig_V-set |
Pfami | View protein in Pfam PF07686, V-set, 1 hit |
SMARTi | View protein in SMART SM00409, IG, 1 hit |
SUPFAMi | SSF48726, SSF48726, 2 hits |
PROSITEi | View protein in PROSITE PS50835, IG_LIKE, 1 hit |
MobiDBi | Search... |
Entry informationi
Entry namei | SLAF9_MOUSE | |
Accessioni | Q9D780Primary (citable) accession number: Q9D780 Secondary accession number(s): Q8BTK0, Q8VE93 | |
Entry historyi | Integrated into UniProtKB/Swiss-Prot: | October 11, 2005 |
Last sequence update: | October 11, 2005 | |
Last modified: | May 25, 2022 | |
This is version 129 of the entry and version 2 of the sequence. See complete history. | ||
Entry statusi | Reviewed (UniProtKB/Swiss-Prot) | |
Annotation program | Chordata Protein Annotation Program |
Miscellaneousi
Keywords - Technical termi
Reference proteomeDocuments
- MGD cross-references
Mouse Genome Database (MGD) cross-references in UniProtKB/Swiss-Prot