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UniProtKB - Q9D6A3 (Q9D6A3_MOUSE)
Protein
SAM domain-containing protein
Gene
Trp73
Organism
Mus musculus (Mouse)
Status
Functioni
GO - Molecular functioni
- DNA binding Source: InterPro
- DNA-binding transcription factor activity Source: InterPro
- metal ion binding Source: UniProtKB-KW
GO - Biological processi
- apoptotic process Source: UniProtKB-KW
- negative regulation of signal transduction Source: UniProt
- nervous system development Source: UniProt
- positive regulation of apoptotic process Source: UniProt
- protein tetramerization Source: InterPro
- regulation of apoptotic signaling pathway Source: UniProt
- regulation of cell cycle Source: InterPro
Keywordsi
Biological process | ApoptosisARBA annotation |
Names & Taxonomyi
Protein namesi | Recommended name: SAM domain-containing proteinInterPro annotation |
Gene namesi | Name:Trp73Imported |
Organismi | Mus musculus (Mouse)Imported |
Taxonomic identifieri | 10090 [NCBI] |
Taxonomic lineagei | Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Glires › Rodentia › Myomorpha › Muroidea › Muridae › Murinae › Mus › Mus |
Organism-specific databases
MGIi | MGI:1336991, Trp73 |
Structurei
Family & Domainsi
Domains and Repeats
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Domaini | 134 – 200 | SAMInterPro annotationAdd BLAST | 67 |
Phylogenomic databases
OrthoDBi | 257530at2759 |
Family and domain databases
CDDi | cd09571, SAM_tumor-p73, 1 hit |
Gene3Di | 1.10.150.50, 1 hit 4.10.170.10, 1 hit |
InterProi | View protein in InterPro IPR036674, p53_tetramer_sf IPR010991, p53_tetrameristn IPR002117, p53_tumour_suppressor IPR001660, SAM IPR013761, SAM/pointed_sf IPR032646, Tp73 IPR037612, Tumour-p73_SAM |
PANTHERi | PTHR11447, PTHR11447, 1 hit PTHR11447:SF21, PTHR11447:SF21, 1 hit |
Pfami | View protein in Pfam PF07710, P53_tetramer, 1 hit PF07647, SAM_2, 1 hit |
SMARTi | View protein in SMART SM00454, SAM, 1 hit |
SUPFAMi | SSF47719, SSF47719, 1 hit SSF47769, SSF47769, 1 hit |
i Sequence
Sequence statusi: Complete.
Q9D6A3-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MFYMHVRGRE NFEILMKVKE SLELMELVPQ PLVDSYRQQQ QQQLLQRPSH
60 70 80 90 100
LQPPSYGPVL SPMNKVHGGV NKLPSVNQLV GQPPPHSSAA GPNLGPMGSG
110 120 130 140 150
MLNSHGHSMP ANGEMNGGHS SQTMVSGSHC TPPPPYHADP SLVSFLTGLG
160 170 180 190 200
CPNCIECFTS QGLQSIYHLQ NLTIEDLGAL KVPDQYRMTI WRGLQDLKQS
210 220 230 240 250
HDCGQQLLRS SSNAATISIG GSGELQRQRV MEAVHFRVRH TITIPNRGGA
260 270 280
GAVTGPDEWA DFGFDLPDCK SRKQPIKEEF TETESH
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AK014503 mRNA Translation: BAB29401.1 |
RefSeqi | NP_001119802.1, NM_001126330.1 NP_001119803.1, NM_001126331.1 NP_035772.2, NM_011642.3 |
Genome annotation databases
GeneIDi | 22062 |
KEGGi | mmu:22062 |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AK014503 mRNA Translation: BAB29401.1 |
RefSeqi | NP_001119802.1, NM_001126330.1 NP_001119803.1, NM_001126331.1 NP_035772.2, NM_011642.3 |
3D structure databases
ModBasei | Search... |
SWISS-MODEL-Workspacei | Submit a new modelling project... |
Protocols and materials databases
DNASUi | 22062 |
Genome annotation databases
GeneIDi | 22062 |
KEGGi | mmu:22062 |
Organism-specific databases
CTDi | 22062 |
MGIi | MGI:1336991, Trp73 |
Phylogenomic databases
OrthoDBi | 257530at2759 |
Miscellaneous databases
BioGRID-ORCSi | 22062, 1 hit in 64 CRISPR screens |
ChiTaRSi | Trp73, mouse |
SOURCEi | Search... |
Gene expression databases
Genevisiblei | Q9D6A3, MM |
Family and domain databases
CDDi | cd09571, SAM_tumor-p73, 1 hit |
Gene3Di | 1.10.150.50, 1 hit 4.10.170.10, 1 hit |
InterProi | View protein in InterPro IPR036674, p53_tetramer_sf IPR010991, p53_tetrameristn IPR002117, p53_tumour_suppressor IPR001660, SAM IPR013761, SAM/pointed_sf IPR032646, Tp73 IPR037612, Tumour-p73_SAM |
PANTHERi | PTHR11447, PTHR11447, 1 hit PTHR11447:SF21, PTHR11447:SF21, 1 hit |
Pfami | View protein in Pfam PF07710, P53_tetramer, 1 hit PF07647, SAM_2, 1 hit |
SMARTi | View protein in SMART SM00454, SAM, 1 hit |
SUPFAMi | SSF47719, SSF47719, 1 hit SSF47769, SSF47769, 1 hit |
MobiDBi | Search... |
Entry informationi
Entry namei | Q9D6A3_MOUSE | |
Accessioni | Q9D6A3Primary (citable) accession number: Q9D6A3 | |
Entry historyi | Integrated into UniProtKB/TrEMBL: | June 1, 2001 |
Last sequence update: | June 1, 2001 | |
Last modified: | January 19, 2022 | |
This is version 136 of the entry and version 1 of the sequence. See complete history. | ||
Entry statusi | Unreviewed (UniProtKB/TrEMBL) |