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Protein

Chromodomain Y-like protein 2

Gene

Cdyl2

Organism
Mus musculus (Mouse)
Status
Reviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

  • catalytic activity Source: InterPro
  • methylated histone binding Source: MGI
  • transcription corepressor activity Source: GO_Central

Names & Taxonomyi

Protein namesi
Recommended name:
Chromodomain Y-like protein 2
Short name:
CDY-like 2
Gene namesi
Name:Cdyl2
OrganismiMus musculus (Mouse)
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeMusMus
Proteomesi
  • UP000000589 Componenti: Chromosome 8

Organism-specific databases

MGIiMGI:1923046 Cdyl2

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

Nucleus

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00004245941 – 503Chromodomain Y-like protein 2Add BLAST503

Proteomic databases

EPDiQ9D5D8
MaxQBiQ9D5D8
PaxDbiQ9D5D8
PRIDEiQ9D5D8

PTM databases

iPTMnetiQ9D5D8
PhosphoSitePlusiQ9D5D8

Expressioni

Gene expression databases

BgeeiENSMUSG00000031758 Expressed in 201 organ(s), highest expression level in pituitary gland
GenevisibleiQ9D5D8 MM

Interactioni

Subunit structurei

Interacts (via chromo domain) with histone H3K9me3.1 Publication

GO - Molecular functioni

Protein-protein interaction databases

BioGridi217748, 1 interactor
STRINGi10090.ENSMUSP00000104730

Structurei

3D structure databases

ProteinModelPortaliQ9D5D8
SMRiQ9D5D8
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini7 – 67ChromoPROSITE-ProRule annotationAdd BLAST61

Phylogenomic databases

eggNOGiKOG0016 Eukaryota
KOG1911 Eukaryota
COG1024 LUCA
GeneTreeiENSGT00890000139344
HOVERGENiHBG006723
InParanoidiQ9D5D8
KOiK00653
OMAiGSNEDTW
OrthoDBiEOG091G0T5I
PhylomeDBiQ9D5D8
TreeFamiTF313375

Family and domain databases

CDDicd00024 CHROMO, 1 hit
Gene3Di1.10.12.10, 1 hit
InterProiView protein in InterPro
IPR016197 Chromo-like_dom_sf
IPR000953 Chromo/chromo_shadow_dom
IPR023780 Chromo_domain
IPR023779 Chromodomain_CS
IPR029045 ClpP/crotonase-like_dom_sf
IPR001753 Enoyl-CoA_hydra/iso
IPR014748 Enoyl-CoA_hydra_C
PfamiView protein in Pfam
PF00385 Chromo, 1 hit
PF00378 ECH_1, 1 hit
SMARTiView protein in SMART
SM00298 CHROMO, 1 hit
SUPFAMiSSF52096 SSF52096, 1 hit
SSF54160 SSF54160, 1 hit
PROSITEiView protein in PROSITE
PS00598 CHROMO_1, 1 hit
PS50013 CHROMO_2, 1 hit

Sequencei

Sequence statusi: Complete.

Q9D5D8-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MASGDLYEVE RIVDKRKNKK GKWEYLIRWK GYGSTEDTWE PEHHLLHCEE
60 70 80 90 100
FIDEFNGLHL SKDKRVKSGK QAGASKLLRD ARGLPVERLS HRPLEPGKSK
110 120 130 140 150
PSSHKRKRVN SPLSRPKKGS SGKAPDRATK TVSYRTTPSG LQIMPLKKAQ
160 170 180 190 200
NGLENGDAGS EKDESHFGNG SHQPDLELND QLGEQEASDC DGTHSALVEN
210 220 230 240 250
GVGSALTNGG LNLHSPVKRK LETEKDYVFD KRLRYSVRQN ESNCRFRDIV
260 270 280 290 300
VRKEEGFTHI LLSSQTSDNN ALTPEIMKEV RRALCNAATD DSKLLLLSAV
310 320 330 340 350
GSVFCSGLDY SYLIGRLSSD RRKESTRIAE AIRDFVKAFI QFKKPIVVAI
360 370 380 390 400
NGPALGLGAS ILPLCDIVWA SEKAWFQTPY ATIRLTPAGC SSYTFPQILG
410 420 430 440 450
VALANEMLFC GRKLTAQEAC SRGLVSQVFW PTTFSQEVML RVKEMASCSA
460 470 480 490 500
VVLEESKCLV RSFLKSVLEE VNEKECVMLK QLWSSSKGLD SLFSYLQDKI

YEV
Length:503
Mass (Da):56,142
Last modified:June 1, 2001 - v1
Checksum:iAE9F2426CA963B26
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK015452 mRNA Translation: BAB29852.1
AC108439 Genomic DNA No translation available.
AC112969 Genomic DNA No translation available.
CH466525 Genomic DNA Translation: EDL11564.1
BC058956 mRNA Translation: AAH58956.1
CCDSiCCDS40488.1
RefSeqiNP_083717.1, NM_029441.3
UniGeneiMm.159575

Genome annotation databases

EnsembliENSMUST00000109102; ENSMUSP00000104730; ENSMUSG00000031758
GeneIDi75796
KEGGimmu:75796
UCSCiuc009noi.2 mouse

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK015452 mRNA Translation: BAB29852.1
AC108439 Genomic DNA No translation available.
AC112969 Genomic DNA No translation available.
CH466525 Genomic DNA Translation: EDL11564.1
BC058956 mRNA Translation: AAH58956.1
CCDSiCCDS40488.1
RefSeqiNP_083717.1, NM_029441.3
UniGeneiMm.159575

3D structure databases

ProteinModelPortaliQ9D5D8
SMRiQ9D5D8
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi217748, 1 interactor
STRINGi10090.ENSMUSP00000104730

PTM databases

iPTMnetiQ9D5D8
PhosphoSitePlusiQ9D5D8

Proteomic databases

EPDiQ9D5D8
MaxQBiQ9D5D8
PaxDbiQ9D5D8
PRIDEiQ9D5D8

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSMUST00000109102; ENSMUSP00000104730; ENSMUSG00000031758
GeneIDi75796
KEGGimmu:75796
UCSCiuc009noi.2 mouse

Organism-specific databases

CTDi124359
MGIiMGI:1923046 Cdyl2

Phylogenomic databases

eggNOGiKOG0016 Eukaryota
KOG1911 Eukaryota
COG1024 LUCA
GeneTreeiENSGT00890000139344
HOVERGENiHBG006723
InParanoidiQ9D5D8
KOiK00653
OMAiGSNEDTW
OrthoDBiEOG091G0T5I
PhylomeDBiQ9D5D8
TreeFamiTF313375

Miscellaneous databases

ChiTaRSiCdyl2 mouse
PROiPR:Q9D5D8
SOURCEiSearch...

Gene expression databases

BgeeiENSMUSG00000031758 Expressed in 201 organ(s), highest expression level in pituitary gland
GenevisibleiQ9D5D8 MM

Family and domain databases

CDDicd00024 CHROMO, 1 hit
Gene3Di1.10.12.10, 1 hit
InterProiView protein in InterPro
IPR016197 Chromo-like_dom_sf
IPR000953 Chromo/chromo_shadow_dom
IPR023780 Chromo_domain
IPR023779 Chromodomain_CS
IPR029045 ClpP/crotonase-like_dom_sf
IPR001753 Enoyl-CoA_hydra/iso
IPR014748 Enoyl-CoA_hydra_C
PfamiView protein in Pfam
PF00385 Chromo, 1 hit
PF00378 ECH_1, 1 hit
SMARTiView protein in SMART
SM00298 CHROMO, 1 hit
SUPFAMiSSF52096 SSF52096, 1 hit
SSF54160 SSF54160, 1 hit
PROSITEiView protein in PROSITE
PS00598 CHROMO_1, 1 hit
PS50013 CHROMO_2, 1 hit
ProtoNetiSearch...

Entry informationi

Entry nameiCDYL2_MOUSE
AccessioniPrimary (citable) accession number: Q9D5D8
Entry historyiIntegrated into UniProtKB/Swiss-Prot: December 11, 2013
Last sequence update: June 1, 2001
Last modified: November 7, 2018
This is version 129 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. MGD cross-references
    Mouse Genome Database (MGD) cross-references in UniProtKB/Swiss-Prot
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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