UniProtKB - Q9D3L3 (Q9D3L3_MOUSE)
Protein
Synaptosomal-associated protein
Gene
Snap23
Organism
Mus musculus (Mouse)
Status
Functioni
GO - Molecular functioni
- syntaxin binding Source: Ensembl
GO - Biological processi
- histamine secretion by mast cell Source: Ensembl
Names & Taxonomyi
Protein namesi | Recommended name: Synaptosomal-associated proteinUniRule annotation |
Gene namesi | Name:Snap23Imported |
Organismi | Mus musculus (Mouse)Imported |
Taxonomic identifieri | 10090 [NCBI] |
Taxonomic lineagei | Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Glires › Rodentia › Myomorpha › Muroidea › Muridae › Murinae › Mus › Mus |
Proteomesi |
|
Organism-specific databases
MGIi | MGI:109356, Snap23 |
Subcellular locationi
Plasma membrane
- Cell membrane ARBA annotation; Lipid-anchor ARBA annotation
Other locations
- synaptosome ARBA annotation
- Membrane ARBA annotation; Lipid-anchor ARBA annotation
Lysosome
- azurophil granule Source: Ensembl
Mitochondrion
- mitochondrion Source: Ensembl
Nucleus
- nucleoplasm Source: Ensembl
Plasma Membrane
- plasma membrane Source: UniProtKB-SubCell
Other locations
- adherens junction Source: Ensembl
- neuron projection Source: UniProtKB-SubCell
- SNARE complex Source: Ensembl
- specific granule Source: Ensembl
- synapse Source: UniProtKB-KW
Keywords - Cellular componenti
Cell junction, Synapse, SynaptosomeARBA annotationExpressioni
Gene expression databases
Bgeei | ENSMUSG00000027287, Expressed in blood and 297 other tissues |
ExpressionAtlasi | Q9D3L3, baseline and differential |
Family & Domainsi
Domains and Repeats
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Domaini | 14 – 76 | T-SNARE coiled-coil homologyInterPro annotationAdd BLAST | 63 | |
Domaini | 156 – 218 | T-SNARE coiled-coil homologyInterPro annotationAdd BLAST | 63 |
Region
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Regioni | 115 – 147 | DisorderedSequence analysisAdd BLAST | 33 |
Coiled coil
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Coiled coili | 45 – 79 | Sequence analysisAdd BLAST | 35 | |
Coiled coili | 187 – 207 | Sequence analysisAdd BLAST | 21 |
Compositional bias
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Compositional biasi | 116 – 147 | PolarSequence analysisAdd BLAST | 32 |
Sequence similaritiesi
Keywords - Domaini
Coiled coilPROSITE-ProRule annotationARBA annotation, RepeatARBA annotationPhylogenomic databases
GeneTreei | ENSGT00950000182843 |
OrthoDBi | 1358184at2759 |
TreeFami | TF315125 |
Family and domain databases
InterProi | View protein in InterPro IPR000928, SNAP-25_dom IPR000727, T_SNARE_dom |
Pfami | View protein in Pfam PF00835, SNAP-25, 1 hit |
SMARTi | View protein in SMART SM00397, t_SNARE, 2 hits |
PROSITEi | View protein in PROSITE PS50192, T_SNARE, 2 hits |
(1+)i Sequence
Sequence statusi: Complete.
This entry has 1 described isoform and 4 potential isoforms that are computationally mapped.Show allAlign All
Q9D3L3-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MDNLSPEEVQ LRAHQVTDES LESTRRILGL AIESQDAGIK TITMLDEQGE
60 70 80 90 100
QLNRIEEGMD QINKDMREAE KTLTELNKCC GLCICPCNRF SVGDCFFETR
110 120 130 140 150
TKNFESGKNY KATWGDGGDN SPSNVVSKQP SRITNGQPQQ TTGAASGGYI
160 170 180 190 200
KRITNDARED EMEENLTQVG SILGNLKNMA LDMGNEIDAQ NQQIQKITEK
210 220
ADTNKNRIDI ANTRAKKLID S
Computationally mapped potential isoform sequencesi
There are 4 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basketO09044 | SNP23_MOUSE | Synaptosomal-associated protein 23 | Snap23 Sndt | 210 | Annotation score: | ||
B0R030 | B0R030_MOUSE | Synaptosomal-associated protein | Snap23 | 161 | Annotation score: | ||
B0R029 | B0R029_MOUSE | Synaptosomal-associated protein 23 | Snap23 | 85 | Annotation score: | ||
E9Q8A1 | E9Q8A1_MOUSE | Synaptosomal-associated protein 23 | Snap23 | 98 | Annotation score: |
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AL772299 Genomic DNA No translation available. AK017311 mRNA Translation: BAB30686.1 |
RefSeqi | NP_001171263.1, NM_001177792.1 XP_006499117.1, XM_006499054.3 XP_006499118.1, XM_006499055.3 XP_006499119.1, XM_006499056.3 |
Genome annotation databases
Ensembli | ENSMUST00000116437; ENSMUSP00000112138; ENSMUSG00000027287 |
GeneIDi | 20619 |
UCSCi | uc008lwh.1, mouse |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AL772299 Genomic DNA No translation available. AK017311 mRNA Translation: BAB30686.1 |
RefSeqi | NP_001171263.1, NM_001177792.1 XP_006499117.1, XM_006499054.3 XP_006499118.1, XM_006499055.3 XP_006499119.1, XM_006499056.3 |
3D structure databases
ModBasei | Search... |
SWISS-MODEL-Workspacei | Submit a new modelling project... |
PTM databases
SwissPalmi | Q9D3L3 |
Proteomic databases
PRIDEi | Q9D3L3 |
Protocols and materials databases
Antibodypediai | 712, 412 antibodies |
Genome annotation databases
Ensembli | ENSMUST00000116437; ENSMUSP00000112138; ENSMUSG00000027287 |
GeneIDi | 20619 |
UCSCi | uc008lwh.1, mouse |
Organism-specific databases
CTDi | 8773 |
MGIi | MGI:109356, Snap23 |
Phylogenomic databases
GeneTreei | ENSGT00950000182843 |
OrthoDBi | 1358184at2759 |
TreeFami | TF315125 |
Miscellaneous databases
BioGRID-ORCSi | 20619, 7 hits in 18 CRISPR screens |
ChiTaRSi | Snap23, mouse |
SOURCEi | Search... |
Gene expression databases
Bgeei | ENSMUSG00000027287, Expressed in blood and 297 other tissues |
ExpressionAtlasi | Q9D3L3, baseline and differential |
Family and domain databases
InterProi | View protein in InterPro IPR000928, SNAP-25_dom IPR000727, T_SNARE_dom |
Pfami | View protein in Pfam PF00835, SNAP-25, 1 hit |
SMARTi | View protein in SMART SM00397, t_SNARE, 2 hits |
PROSITEi | View protein in PROSITE PS50192, T_SNARE, 2 hits |
ProtoNeti | Search... |
MobiDBi | Search... |
Entry informationi
Entry namei | Q9D3L3_MOUSE | |
Accessioni | Q9D3L3Primary (citable) accession number: Q9D3L3 | |
Entry historyi | Integrated into UniProtKB/TrEMBL: | June 1, 2001 |
Last sequence update: | June 1, 2001 | |
Last modified: | February 10, 2021 | |
This is version 143 of the entry and version 1 of the sequence. See complete history. | ||
Entry statusi | Unreviewed (UniProtKB/TrEMBL) |