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Protein

Transmembrane protein 80

Gene

Tmem80

Organism
Mus musculus (Mouse)
Status
Reviewed-Annotation score: -Experimental evidence at transcript leveli

Names & Taxonomyi

Protein namesi
Recommended name:
Transmembrane protein 80
Gene namesi
Name:Tmem80
OrganismiMus musculus (Mouse)
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeMusMus
Proteomesi
  • UP000000589 Componenti: Chromosome 7

Organism-specific databases

MGIiMGI:1918698 Tmem80

Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei2 – 22HelicalSequence analysisAdd BLAST21
Transmembranei35 – 55HelicalSequence analysisAdd BLAST21
Transmembranei68 – 88HelicalSequence analysisAdd BLAST21
Transmembranei102 – 122HelicalSequence analysisAdd BLAST21

Keywords - Cellular componenti

Cell projection, Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00002878741 – 123Transmembrane protein 80Add BLAST123

Proteomic databases

PaxDbiQ9D3H0
PRIDEiQ9D3H0

PTM databases

PhosphoSitePlusiQ9D3H0

Expressioni

Gene expression databases

BgeeiENSMUSG00000025505 Expressed in 251 organ(s), highest expression level in humerus cartilage element
CleanExiMM_TMEM80
GenevisibleiQ9D3H0 MM

Interactioni

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000026578

Family & Domainsi

Keywords - Domaini

Transmembrane, Transmembrane helix

Phylogenomic databases

eggNOGiENOG410J0JJ Eukaryota
ENOG4112C55 LUCA
GeneTreeiENSGT00390000002170
HOGENOMiHOG000008106
HOVERGENiHBG059533
InParanoidiQ9D3H0
OMAiLYLGTKG
OrthoDBiEOG091G0UR4
PhylomeDBiQ9D3H0
TreeFamiTF323824

Family and domain databases

InterProiView protein in InterPro
IPR019184 Uncharacterised_TM-17
PANTHERiPTHR13531 PTHR13531, 1 hit
PfamiView protein in Pfam
PF09799 Transmemb_17, 1 hit

Sequences (2)i

Sequence statusi: Complete.

This entry describes 2 isoformsi produced by alternative splicing. AlignAdd to basket
Isoform 1 (identifier: Q9D3H0-1) [UniParc]FASTAAdd to basket

This isoform has been chosen as the 'canonical' sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

« Hide
        10         20         30         40         50
MLFHLSGLYS ALYFLATLLM IVYKSQVFSY PCNCLALDLV LLLLMGILKV
60 70 80 90 100
AQLYLGTKGN LMEAEVPLAA SLAFTAVGGL LSVHFLLWQT LVLWMDSVLS
110 120
TVLLVLHGLE AGLQVVVIAD FIR
Length:123
Mass (Da):13,473
Last modified:June 1, 2001 - v1
Checksum:iD529466CD787D6D0
GO
Isoform 2 (identifier: Q9D3H0-2) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     26-56: Missing.

Show »
Length:92
Mass (Da):10,066
Checksum:i6E209D5723153782
GO

Alternative sequence

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Alternative sequenceiVSP_02561126 – 56Missing in isoform 2. 1 PublicationAdd BLAST31

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK017460 mRNA Translation: BAB30753.1
AK049405 mRNA Translation: BAC33737.1
AK134821 mRNA Translation: BAE22300.1
AK169083 mRNA Translation: BAE40867.1
BC022756 mRNA Translation: AAH22756.1
CCDSiCCDS22008.1 [Q9D3H0-1]
RefSeqiNP_001135422.1, NM_001141950.1 [Q9D3H0-1]
NP_082073.1, NM_027797.3 [Q9D3H0-1]
XP_011248160.1, XM_011249858.1 [Q9D3H0-1]
UniGeneiMm.248960

Genome annotation databases

EnsembliENSMUST00000026578; ENSMUSP00000026578; ENSMUSG00000025505 [Q9D3H0-1]
ENSMUST00000126510; ENSMUSP00000123330; ENSMUSG00000025505 [Q9D3H0-1]
ENSMUST00000128906; ENSMUSP00000117306; ENSMUSG00000025505 [Q9D3H0-2]
ENSMUST00000132061; ENSMUSP00000118223; ENSMUSG00000025505 [Q9D3H0-1]
ENSMUST00000133012; ENSMUSP00000116695; ENSMUSG00000025505 [Q9D3H0-1]
ENSMUST00000145184; ENSMUSP00000117633; ENSMUSG00000025505 [Q9D3H0-2]
GeneIDi71448
KEGGimmu:71448
UCSCiuc009kkq.2 mouse [Q9D3H0-1]

Keywords - Coding sequence diversityi

Alternative splicing

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK017460 mRNA Translation: BAB30753.1
AK049405 mRNA Translation: BAC33737.1
AK134821 mRNA Translation: BAE22300.1
AK169083 mRNA Translation: BAE40867.1
BC022756 mRNA Translation: AAH22756.1
CCDSiCCDS22008.1 [Q9D3H0-1]
RefSeqiNP_001135422.1, NM_001141950.1 [Q9D3H0-1]
NP_082073.1, NM_027797.3 [Q9D3H0-1]
XP_011248160.1, XM_011249858.1 [Q9D3H0-1]
UniGeneiMm.248960

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000026578

PTM databases

PhosphoSitePlusiQ9D3H0

Proteomic databases

PaxDbiQ9D3H0
PRIDEiQ9D3H0

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSMUST00000026578; ENSMUSP00000026578; ENSMUSG00000025505 [Q9D3H0-1]
ENSMUST00000126510; ENSMUSP00000123330; ENSMUSG00000025505 [Q9D3H0-1]
ENSMUST00000128906; ENSMUSP00000117306; ENSMUSG00000025505 [Q9D3H0-2]
ENSMUST00000132061; ENSMUSP00000118223; ENSMUSG00000025505 [Q9D3H0-1]
ENSMUST00000133012; ENSMUSP00000116695; ENSMUSG00000025505 [Q9D3H0-1]
ENSMUST00000145184; ENSMUSP00000117633; ENSMUSG00000025505 [Q9D3H0-2]
GeneIDi71448
KEGGimmu:71448
UCSCiuc009kkq.2 mouse [Q9D3H0-1]

Organism-specific databases

CTDi283232
MGIiMGI:1918698 Tmem80

Phylogenomic databases

eggNOGiENOG410J0JJ Eukaryota
ENOG4112C55 LUCA
GeneTreeiENSGT00390000002170
HOGENOMiHOG000008106
HOVERGENiHBG059533
InParanoidiQ9D3H0
OMAiLYLGTKG
OrthoDBiEOG091G0UR4
PhylomeDBiQ9D3H0
TreeFamiTF323824

Miscellaneous databases

PROiPR:Q9D3H0
SOURCEiSearch...

Gene expression databases

BgeeiENSMUSG00000025505 Expressed in 251 organ(s), highest expression level in humerus cartilage element
CleanExiMM_TMEM80
GenevisibleiQ9D3H0 MM

Family and domain databases

InterProiView protein in InterPro
IPR019184 Uncharacterised_TM-17
PANTHERiPTHR13531 PTHR13531, 1 hit
PfamiView protein in Pfam
PF09799 Transmemb_17, 1 hit
ProtoNetiSearch...

Entry informationi

Entry nameiTMM80_MOUSE
AccessioniPrimary (citable) accession number: Q9D3H0
Secondary accession number(s): Q8BQL4
Entry historyiIntegrated into UniProtKB/Swiss-Prot: May 15, 2007
Last sequence update: June 1, 2001
Last modified: September 12, 2018
This is version 99 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. MGD cross-references
    Mouse Genome Database (MGD) cross-references in UniProtKB/Swiss-Prot
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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