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Protein

Syntaxin-11

Gene

Stx11

Organism
Mus musculus (Mouse)
Status
Reviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

SNARE that acts to regulate protein transport between late endosomes and the trans-Golgi network.By similarity

GO - Molecular functioni

GO - Biological processi

Keywordsi

Biological processProtein transport, Transport

Names & Taxonomyi

Protein namesi
Recommended name:
Syntaxin-11
Gene namesi
Name:Stx11
OrganismiMus musculus (Mouse)
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeMusMus
Proteomesi
  • UP000000589 Componenti: Unplaced

Organism-specific databases

MGIiMGI:1921982 Stx11

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

Golgi apparatus, Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00002102221 – 287Syntaxin-11Add BLAST287

Proteomic databases

EPDiQ9D3G5
MaxQBiQ9D3G5
PaxDbiQ9D3G5
PRIDEiQ9D3G5

PTM databases

iPTMnetiQ9D3G5
PhosphoSitePlusiQ9D3G5
SwissPalmiQ9D3G5

Expressioni

Gene expression databases

CleanExiMM_STX11

Interactioni

Subunit structurei

Interacts with the SNARE proteins SNAP-23 and VAMP.By similarity

GO - Molecular functioni

Protein-protein interaction databases

IntActiQ9D3G5, 1 interactor
STRINGi10090.ENSMUSP00000046243

Structurei

3D structure databases

ProteinModelPortaliQ9D3G5
SMRiQ9D3G5
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini204 – 266t-SNARE coiled-coil homologyPROSITE-ProRule annotationAdd BLAST63

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Coiled coili41 – 71Sequence analysisAdd BLAST31

Sequence similaritiesi

Belongs to the syntaxin family.Curated

Keywords - Domaini

Coiled coil

Phylogenomic databases

eggNOGiKOG0810 Eukaryota
COG5074 LUCA
HOGENOMiHOG000286023
HOVERGENiHBG099780
InParanoidiQ9D3G5
KOiK08487
PhylomeDBiQ9D3G5

Family and domain databases

CDDicd00179 SynN, 1 hit
InterProiView protein in InterPro
IPR010989 SNARE
IPR028672 STX11
IPR006012 Syntaxin/epimorphin_CS
IPR006011 Syntaxin_N
IPR000727 T_SNARE_dom
PANTHERiPTHR19957:SF30 PTHR19957:SF30, 1 hit
PfamiView protein in Pfam
PF00804 Syntaxin, 1 hit
SMARTiView protein in SMART
SM00503 SynN, 1 hit
SM00397 t_SNARE, 1 hit
SUPFAMiSSF47661 SSF47661, 1 hit
PROSITEiView protein in PROSITE
PS00914 SYNTAXIN, 1 hit
PS50192 T_SNARE, 1 hit

Sequence (1+)i

Sequence statusi: Complete.

This entry has 1 described isoform and 3 potential isoforms that are computationally mapped.Show allAlign All

Q9D3G5-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MKDRLAELQE LSRSYDQQFP DGDNDFDAPR EDIVFETDNI LESLYRVIQD
60 70 80 90 100
IQDENQLLLI DVRRLGRQNV RFLTSMRRLS SIKRDTNSIA KAIKTRGEGI
110 120 130 140 150
HQKLRSMKEL SEQAEARHGA HSAVARISHA QYSALARAFQ QAMYEYNQAE
160 170 180 190 200
MKQRDNCKIR IQRQLEIMGK DMSGEQIEDM FEQGKWDVFS ENLLADLKGA
210 220 230 240 250
RAALNEIESR HRELLRLEGR IRDVHELFLQ MAVLVEKQED TLNVIELNVQ
260 270 280
KTLDYTGEAK AQVRKAVQYK KKNPCRTICC FCCPCVN
Length:287
Mass (Da):33,369
Last modified:June 1, 2001 - v1
Checksum:iFD5D10842B7C5415
GO

Computationally mapped potential isoform sequencesi

There are 3 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
Q3U5V8Q3U5V8_MOUSE
MCG49559
Stx11 mCG_49559
287Annotation score:
A0A1W2P6Y3A0A1W2P6Y3_MOUSE
Syntaxin-11
Stx11
84Annotation score:
A0A1W2P6E3A0A1W2P6E3_MOUSE
Syntaxin-11
Stx11
50Annotation score:

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK017897 mRNA Translation: BAB30994.1
CCDSiCCDS48500.1
RefSeqiNP_083351.1, NM_029075.1
UniGeneiMm.248648

Genome annotation databases

GeneIDi74732
KEGGimmu:74732

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK017897 mRNA Translation: BAB30994.1
CCDSiCCDS48500.1
RefSeqiNP_083351.1, NM_029075.1
UniGeneiMm.248648

3D structure databases

ProteinModelPortaliQ9D3G5
SMRiQ9D3G5
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

IntActiQ9D3G5, 1 interactor
STRINGi10090.ENSMUSP00000046243

PTM databases

iPTMnetiQ9D3G5
PhosphoSitePlusiQ9D3G5
SwissPalmiQ9D3G5

Proteomic databases

EPDiQ9D3G5
MaxQBiQ9D3G5
PaxDbiQ9D3G5
PRIDEiQ9D3G5

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

GeneIDi74732
KEGGimmu:74732

Organism-specific databases

CTDi8676
MGIiMGI:1921982 Stx11

Phylogenomic databases

eggNOGiKOG0810 Eukaryota
COG5074 LUCA
HOGENOMiHOG000286023
HOVERGENiHBG099780
InParanoidiQ9D3G5
KOiK08487
PhylomeDBiQ9D3G5

Miscellaneous databases

PROiPR:Q9D3G5
SOURCEiSearch...

Gene expression databases

CleanExiMM_STX11

Family and domain databases

CDDicd00179 SynN, 1 hit
InterProiView protein in InterPro
IPR010989 SNARE
IPR028672 STX11
IPR006012 Syntaxin/epimorphin_CS
IPR006011 Syntaxin_N
IPR000727 T_SNARE_dom
PANTHERiPTHR19957:SF30 PTHR19957:SF30, 1 hit
PfamiView protein in Pfam
PF00804 Syntaxin, 1 hit
SMARTiView protein in SMART
SM00503 SynN, 1 hit
SM00397 t_SNARE, 1 hit
SUPFAMiSSF47661 SSF47661, 1 hit
PROSITEiView protein in PROSITE
PS00914 SYNTAXIN, 1 hit
PS50192 T_SNARE, 1 hit
ProtoNetiSearch...

Entry informationi

Entry nameiSTX11_MOUSE
AccessioniPrimary (citable) accession number: Q9D3G5
Entry historyiIntegrated into UniProtKB/Swiss-Prot: May 10, 2004
Last sequence update: June 1, 2001
Last modified: September 12, 2018
This is version 111 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families
  2. MGD cross-references
    Mouse Genome Database (MGD) cross-references in UniProtKB/Swiss-Prot
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Main funding by: National Institutes of Health

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