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Entry version 136 (29 Sep 2021)
Sequence version 1 (01 Jun 2001)
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Protein

Protein RUFY3

Gene

Rufy3

Organism
Mus musculus (Mouse)
Status
Reviewed-Annotation score:

Annotation score:5 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Plays a role in the generation of neuronal polarity formation and axon growth (PubMed:24720729).

Implicated in the formation of a single axon by developing neurons (PubMed:24720729).

May inhibit the formation of additional axons by inhibition of PI3K in minor neuronal processes (By similarity).

Plays a role in the formation of F-actin-enriched protrusive structures at the cell periphery (By similarity).

Plays a role in cytoskeletal organization by regulating the subcellular localization of FSCN1 and DBN1 at axonal growth cones (PubMed:24720729).

Promotes gastric cancer cell migration and invasion in a PAK1-dependent manner (By similarity).

By similarity1 Publication

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Biological processi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Molecular functionDevelopmental protein
Biological processDifferentiation, Neurogenesis

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Protein RUFY3Curated
Alternative name(s):
Rap2-interacting protein x1 Publication
Short name:
RIPx1 Publication
Single axon-regulated protein 1By similarity
Short name:
Singar1By similarity
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:Rufy3Imported
Synonyms:D5Bwg0860e, Ripx1 Publication
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiMus musculus (Mouse)
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri10090 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeMusMus
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000000589 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes_manual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 5

Organism-specific databases

Mouse genome database (MGD) from Mouse Genome Informatics (MGI)

More...
MGIi
MGI:106484, Rufy3

Eukaryotic Pathogen, Vector and Host Database Resources

More...
VEuPathDBi
HostDB:ENSMUSG00000029291

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Keywords - Cellular componenti

Cell junction, Cell projection, Cytoplasm, Membrane

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

Keywords - Diseasei

Oncogene

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'PTM / Processing' section describes the extent of a polypeptide chain in the mature protein following processing or proteolytic cleavage.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00002458341 – 469Protein RUFY3Add BLAST469

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'PTM / Processing' section specifies the position and type of each modified residue excluding <a href="http://www.uniprot.org/manual/lipid">lipids</a>, <a href="http://www.uniprot.org/manual/carbohyd">glycans</a> and <a href="http://www.uniprot.org/manual/crosslnk">protein cross-links</a>.<p><a href='/help/mod_res' target='_top'>More...</a></p>Modified residuei5PhosphothreonineBy similarity1
Modified residuei12PhosphothreonineBy similarity1
Modified residuei34PhosphoserineCombined sources1
Modified residuei49PhosphoserineCombined sources1
Modified residuei51PhosphothreonineCombined sources1
Isoform 2 (identifier: Q9D394-2)
Modified residuei27PhosphoserineCombined sources1
Modified residuei49PhosphoserineCombined sources1
Modified residuei53PhosphoserineCombined sources1
Isoform 4 (identifier: Q9D394-4)
Modified residuei27PhosphoserineCombined sources1
Modified residuei49PhosphoserineCombined sources1
Modified residuei53PhosphoserineCombined sources1

<p>This subsection of the <a href="http://www.uniprot.org/help/ptm_processing_section">PTM/processing</a> section describes post-translational modifications (PTMs). This subsection <strong>complements</strong> the information provided at the sequence level or describes modifications for which <strong>position-specific data is not yet available</strong>.<p><a href='/help/post-translational_modification' target='_top'>More...</a></p>Post-translational modificationi

Phosphorylated by PAK1. Isoform 1 is partially phosphorylated.By similarity

Keywords - PTMi

Phosphoprotein

Proteomic databases

jPOST - Japan Proteome Standard Repository/Database

More...
jPOSTi
Q9D394

PaxDb, a database of protein abundance averages across all three domains of life

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PaxDbi
Q9D394

PeptideAtlas

More...
PeptideAtlasi
Q9D394

PRoteomics IDEntifications database

More...
PRIDEi
Q9D394

ProteomicsDB: a multi-organism proteome resource

More...
ProteomicsDBi
256809 [Q9D394-1]
256810 [Q9D394-2]
256811 [Q9D394-3]
256812 [Q9D394-4]

PTM databases

iPTMnet integrated resource for PTMs in systems biology context

More...
iPTMneti
Q9D394

Comprehensive resource for the study of protein post-translational modifications (PTMs) in human, mouse and rat.

More...
PhosphoSitePlusi
Q9D394

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

<p>This subsection of the 'Expression' section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms. By default, the information is derived from experiments at the mRNA level, unless specified 'at protein level'.<br></br>Examples: <a href="http://www.uniprot.org/uniprot/P92958#expression">P92958</a>, <a href="http://www.uniprot.org/uniprot/Q8TDN4#expression">Q8TDN4</a>, <a href="http://www.uniprot.org/uniprot/O14734#expression">O14734</a><p><a href='/help/tissue_specificity' target='_top'>More...</a></p>Tissue specificityi

Expressed in brain (at protein level) (PubMed:24720729).1 Publication

<p>This subsection of the 'Expression' section provides information on the expression of the gene product at various stages of a cell, tissue or organism development. By default, the information is derived from experiments at the mRNA level, unless specified 'at the protein level'.<p><a href='/help/developmental_stage' target='_top'>More...</a></p>Developmental stagei

Expressed during the embryonic brain development from 11.5 dpc, onwards (PubMed:24720729). Expressed in the upper layers of the cortex at 11.5 dpc (PubMed:24720729). Expressed in the intermediate zone to the cortical plate of the cortex at 18.5 dpc (PubMed:24720729). Expressed in neurons (at protein level) (PubMed:24720729).1 Publication

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...
Bgeei
ENSMUSG00000029291, Expressed in mammillary body and 328 other tissues

Genevisible search portal to normalized and curated expression data from Genevestigator

More...
Genevisiblei
Q9D394, MM

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

<p>This subsection of the <a href="http://www.uniprot.org/help/interaction_section">'Interaction'</a> section provides information about the protein quaternary structure and interaction(s) with other proteins or protein complexes (with the exception of physiological receptor-ligand interactions which are annotated in the <a href="http://www.uniprot.org/help/function_section">'Function'</a> section).<p><a href='/help/subunit_structure' target='_top'>More...</a></p>Subunit structurei

Interacts (via N-terminus) with FSCN1; this interaction induces neuron axon development (PubMed:24720729).

Interacts with DBN1 (PubMed:24720729).

Interacts with PAK1 (By similarity).

Interacts (via C-terminus) with Ras-related Rab-5 proteins (By similarity).

Interacts (via C-terminus) with Ras-related Rap-2 proteins (By similarity).

Interacts with PIK3CA and PIK3R1 (By similarity).

By similarity1 Publication

Protein-protein interaction databases

The Biological General Repository for Interaction Datasets (BioGRID)

More...
BioGRIDi
206843, 12 interactors

Molecular INTeraction database

More...
MINTi
Q9D394

STRING: functional protein association networks

More...
STRINGi
10090.ENSMUSP00000031229

Miscellaneous databases

RNAct, Protein-RNA interaction predictions for model organisms.

More...
RNActi
Q9D394, protein

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

Secondary structure

1469
Legend: HelixTurnBeta strandPDB Structure known for this area
Show more details

3D structure databases

SWISS-MODEL Repository - a database of annotated 3D protein structure models

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SMRi
Q9D394

Database of comparative protein structure models

More...
ModBasei
Search...

Protein Data Bank in Europe - Knowledge Base

More...
PDBe-KBi
Search...

Miscellaneous databases

Relative evolutionary importance of amino acids within a protein sequence

More...
EvolutionaryTracei
Q9D394

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family_and_domains_section">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini95 – 227RUNPROSITE-ProRule annotationAdd BLAST133

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes a region of interest that cannot be described in other subsections.<p><a href='/help/region' target='_top'>More...</a></p>Regioni321 – 342DisorderedSequence analysisAdd BLAST22

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and domains' section denotes the positions of regions of coiled coil within the protein.<p><a href='/help/coiled' target='_top'>More...</a></p>Coiled coili267 – 464Sequence analysisAdd BLAST198

Keywords - Domaini

Coiled coil

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

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eggNOGi
KOG4381, Eukaryota

Ensembl GeneTree

More...
GeneTreei
ENSGT00940000156035

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...
HOGENOMi
CLU_014576_0_0_1

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
Q9D394

Database of Orthologous Groups

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OrthoDBi
753155at2759

Database for complete collections of gene phylogenies

More...
PhylomeDBi
Q9D394

TreeFam database of animal gene trees

More...
TreeFami
TF323904

Family and domain databases

Gene3D Structural and Functional Annotation of Protein Families

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Gene3Di
1.20.58.900, 1 hit

Integrated resource of protein families, domains and functional sites

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InterProi
View protein in InterPro
IPR004012, Run_dom
IPR037213, Run_dom_sf

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF02759, RUN, 1 hit

Simple Modular Architecture Research Tool; a protein domain database

More...
SMARTi
View protein in SMART
SM00593, RUN, 1 hit

Superfamily database of structural and functional annotation

More...
SUPFAMi
SSF140741, SSF140741, 1 hit

PROSITE; a protein domain and family database

More...
PROSITEi
View protein in PROSITE
PS50826, RUN, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequences (4+)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

This entry describes 4 <p>This subsection of the 'Sequence' section lists the alternative protein sequences (isoforms) that can be generated from the same gene by a single or by the combination of up to four biological events (alternative promoter usage, alternative splicing, alternative initiation and ribosomal frameshifting). Additionally, this section gives relevant information on each alternative protein isoform.<p><a href='/help/alternative_products' target='_top'>More...</a></p> isoformsi produced by alternative splicing. AlignAdd to basket

This entry has 4 described isoforms and 1 potential isoform that is computationally mapped.Show allAlign All

Isoform 1 (identifier: Q9D394-1) [UniParc]FASTAAdd to basket

This isoform has been chosen as the <div> <p><b>What is the canonical sequence?</b><p><a href='/help/canonical_and_isoforms' target='_top'>More...</a></p>canonicali sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

« Hide
        10         20         30         40         50
MSALTPPTDM PTPTTDKITQ AAMETIYLCK FRVSMDGEWL CLRELDDISL
60 70 80 90 100
TPDPEPTHED PNYLMANERM NLMNMAKLSI KGLIESALNL GRTLDSDYAP
110 120 130 140 150
LQQFFVVMEH CLKHGLKAKK TFLGQNKSFW GPLELVEKLV PEAAEITASV
160 170 180 190 200
KDLPGLKTPV GRGRAWLRLA LMQKKLSEYM KALINKKELL SEFYEVNALM
210 220 230 240 250
MEEEGAIIAG LLVGLNVIDA NFCMKGEDLD SQVGVIDFSM YLKDGNSSKG
260 270 280 290 300
SEGDGQITAI LDQKNYVEEL NRHLNATVNN LQTKVDLLEK SNTKLTEELA
310 320 330 340 350
VANNRIITLQ EEMERVKEES SYLLESNRKG PKQDRTAEGQ ALSEARKHLK
360 370 380 390 400
EETQLRLDVE KELELQISMR QEMELAMKML EKDVCEKQDA LVSLRQQLDD
410 420 430 440 450
LRALKHELAF KLQSSDLGVK QKSELNSRLE EKTNQMAATI KQLEQSEKDL
460
VKQAKTLNSA ANKLIPKHH
Length:469
Mass (Da):53,007
Last modified:June 1, 2001 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:iCFB8D2C3363D06BD
GO
Isoform 2 (identifier: Q9D394-2) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     1-60: MSALTPPTDM...TPDPEPTHED → MAESPAPGAA...GGSGGGGKHH
     446-469: SEKDLVKQAKTLNSAANKLIPKHH → RLRQAERGRQ...CHEQLIKQYS

Show »
Length:665
Mass (Da):74,402
Checksum:iCEC280891CDDDB24
GO
Isoform 3 (identifier: Q9D394-3) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     58-58: H → HEDSWEDLTDLVEQVRADP

Show »
Length:487
Mass (Da):55,106
Checksum:i001CC96640D52649
GO
Isoform 4 (identifier: Q9D394-4) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     1-60: MSALTPPTDM...TPDPEPTHED → MAESPAPGAA...GGSGGGGKHH

Show »
Length:519
Mass (Da):57,455
Checksum:i586AC3EEB2F88E04
GO

<p>In eukaryotic reference proteomes, unreviewed entries that are likely to belong to the same gene are computationally mapped, based on gene identifiers from Ensembl, EnsemblGenomes and model organism databases.<p><a href='/help/gene_centric_isoform_mapping' target='_top'>More...</a></p>Computationally mapped potential isoform sequencesi

There is 1 potential isoform mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
A0A0G2JFT8A0A0G2JFT8_MOUSE
Protein RUFY3
Rufy3
669Annotation score:

Annotation score:2 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Sequence' section reports difference(s) between the canonical sequence (displayed by default in the entry) and the different sequence submissions merged in the entry. These various submissions may originate from different sequencing projects, different types of experiments, or different biological samples. Sequence conflicts are usually of unknown origin.<p><a href='/help/conflict' target='_top'>More...</a></p>Sequence conflicti224M → I in AAH17648 (PubMed:15489334).Curated1
Sequence conflicti251S → G in BAE32941 (PubMed:16141072).Curated1
Isoform 2 (identifier: Q9D394-2)
Sequence conflicti55V → A in BAE32941 (PubMed:16141072).Curated1

Alternative sequence

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Sequence' section describes the sequence of naturally occurring alternative protein isoform(s). The changes in the amino acid sequence may be due to alternative splicing, alternative promoter usage, alternative initiation, or ribosomal frameshifting.<p><a href='/help/var_seq' target='_top'>More...</a></p>Alternative sequenceiVSP_0197921 – 60MSALT…PTHED → MAESPAPGAAAESCGEEQER GGERRPSEPLEPRGASARGA DREDEAGPSEPDSPVAAPFF LLYPGDGGAGFTARPPPQRA WRTPPSPGSPLPFLLLSYPS GGSGGGGKHH in isoform 2 and isoform 4. 1 PublicationAdd BLAST60
Alternative sequenceiVSP_01979358H → HEDSWEDLTDLVEQVRADP in isoform 3. 1 Publication1
Alternative sequenceiVSP_019794446 – 469SEKDL…IPKHH → RLRQAERGRQSAELDNRLFK QDFGDKINSLQLEVEALTRQ RTQLELELKQEKERKSQNRG TPGKGAQKPELRMDGKHRIQ EENVKLKKPLEESHRLLTHP AEEQGQPSLSEKPQVCQLCQ EDDSLTKNTCRNCRGTFCNA CTTNELPLPSSIKPERVCNP CHEQLIKQYS in isoform 2. 1 PublicationAdd BLAST24

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

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GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
AK018184 mRNA Translation: BAB31113.1
AK083242 mRNA Translation: BAC38826.1
AK148795 mRNA Translation: BAE28665.1
AK154941 mRNA Translation: BAE32941.1
CT010404 mRNA Translation: CAJ18610.1
BC017648 mRNA Translation: AAH17648.1
BC049127 mRNA Translation: AAH49127.1
BC058259 mRNA Translation: AAH58259.1

The Consensus CDS (CCDS) project

More...
CCDSi
CCDS19403.1 [Q9D394-1]
CCDS80323.1 [Q9D394-4]
CCDS80325.1 [Q9D394-3]

NCBI Reference Sequences

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RefSeqi
NP_001276704.1, NM_001289775.1 [Q9D394-4]
NP_001276705.1, NM_001289776.1 [Q9D394-3]
NP_001276706.1, NM_001289777.1 [Q9D394-3]
NP_081806.1, NM_027530.3 [Q9D394-1]

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...
Ensembli
ENSMUST00000031229; ENSMUSP00000031229; ENSMUSG00000029291 [Q9D394-1]
ENSMUST00000196686; ENSMUSP00000143209; ENSMUSG00000029291 [Q9D394-3]
ENSMUST00000196894; ENSMUSP00000143770; ENSMUSG00000029291 [Q9D394-4]
ENSMUST00000199312; ENSMUSP00000143115; ENSMUSG00000029291 [Q9D394-3]

Database of genes from NCBI RefSeq genomes

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GeneIDi
52822

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
mmu:52822

UCSC genome browser

More...
UCSCi
uc008xzw.2, mouse [Q9D394-4]
uc008xzx.2, mouse [Q9D394-2]
uc008xzy.2, mouse [Q9D394-3]
uc008xzz.2, mouse [Q9D394-1]

Keywords - Coding sequence diversityi

Alternative splicing

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK018184 mRNA Translation: BAB31113.1
AK083242 mRNA Translation: BAC38826.1
AK148795 mRNA Translation: BAE28665.1
AK154941 mRNA Translation: BAE32941.1
CT010404 mRNA Translation: CAJ18610.1
BC017648 mRNA Translation: AAH17648.1
BC049127 mRNA Translation: AAH49127.1
BC058259 mRNA Translation: AAH58259.1
CCDSiCCDS19403.1 [Q9D394-1]
CCDS80323.1 [Q9D394-4]
CCDS80325.1 [Q9D394-3]
RefSeqiNP_001276704.1, NM_001289775.1 [Q9D394-4]
NP_001276705.1, NM_001289776.1 [Q9D394-3]
NP_001276706.1, NM_001289777.1 [Q9D394-3]
NP_081806.1, NM_027530.3 [Q9D394-1]

3D structure databases

Select the link destinations:

Protein Data Bank Europe

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PDBei

Protein Data Bank RCSB

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RCSB PDBi

Protein Data Bank Japan

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PDBji
Links Updated
PDB entryMethodResolution (Å)ChainPositionsPDBsum
2CXFX-ray3.07A65-247[»]
2CXLX-ray3.20A65-247[»]
2DWGX-ray3.22A/B65-237[»]
2DWKX-ray2.00A65-237[»]
SMRiQ9D394
ModBaseiSearch...
PDBe-KBiSearch...

Protein-protein interaction databases

BioGRIDi206843, 12 interactors
MINTiQ9D394
STRINGi10090.ENSMUSP00000031229

PTM databases

iPTMnetiQ9D394
PhosphoSitePlusiQ9D394

Proteomic databases

jPOSTiQ9D394
PaxDbiQ9D394
PeptideAtlasiQ9D394
PRIDEiQ9D394
ProteomicsDBi256809 [Q9D394-1]
256810 [Q9D394-2]
256811 [Q9D394-3]
256812 [Q9D394-4]

Protocols and materials databases

ABCD curated depository of sequenced antibodies

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ABCDi
Q9D394, 3 sequenced antibodies

Antibodypedia a portal for validated antibodies

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Antibodypediai
12878, 71 antibodies

The DNASU plasmid repository

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DNASUi
52822

Genome annotation databases

EnsembliENSMUST00000031229; ENSMUSP00000031229; ENSMUSG00000029291 [Q9D394-1]
ENSMUST00000196686; ENSMUSP00000143209; ENSMUSG00000029291 [Q9D394-3]
ENSMUST00000196894; ENSMUSP00000143770; ENSMUSG00000029291 [Q9D394-4]
ENSMUST00000199312; ENSMUSP00000143115; ENSMUSG00000029291 [Q9D394-3]
GeneIDi52822
KEGGimmu:52822
UCSCiuc008xzw.2, mouse [Q9D394-4]
uc008xzx.2, mouse [Q9D394-2]
uc008xzy.2, mouse [Q9D394-3]
uc008xzz.2, mouse [Q9D394-1]

Organism-specific databases

Comparative Toxicogenomics Database

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CTDi
22902
MGIiMGI:106484, Rufy3
VEuPathDBiHostDB:ENSMUSG00000029291

Phylogenomic databases

eggNOGiKOG4381, Eukaryota
GeneTreeiENSGT00940000156035
HOGENOMiCLU_014576_0_0_1
InParanoidiQ9D394
OrthoDBi753155at2759
PhylomeDBiQ9D394
TreeFamiTF323904

Miscellaneous databases

BioGRID ORCS database of CRISPR phenotype screens

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BioGRID-ORCSi
52822, 0 hits in 61 CRISPR screens

ChiTaRS: a database of human, mouse and fruit fly chimeric transcripts and RNA-sequencing data

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ChiTaRSi
Rufy3, mouse
EvolutionaryTraceiQ9D394

Protein Ontology

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PROi
PR:Q9D394
RNActiQ9D394, protein

The Stanford Online Universal Resource for Clones and ESTs

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SOURCEi
Search...

Gene expression databases

BgeeiENSMUSG00000029291, Expressed in mammillary body and 328 other tissues
GenevisibleiQ9D394, MM

Family and domain databases

Gene3Di1.20.58.900, 1 hit
InterProiView protein in InterPro
IPR004012, Run_dom
IPR037213, Run_dom_sf
PfamiView protein in Pfam
PF02759, RUN, 1 hit
SMARTiView protein in SMART
SM00593, RUN, 1 hit
SUPFAMiSSF140741, SSF140741, 1 hit
PROSITEiView protein in PROSITE
PS50826, RUN, 1 hit

MobiDB: a database of protein disorder and mobility annotations

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MobiDBi
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiRUFY3_MOUSE
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q9D394
Secondary accession number(s): Q3U348
, Q3UF96, Q6PE64, Q8VD10
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: July 11, 2006
Last sequence update: June 1, 2001
Last modified: September 29, 2021
This is version 136 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

3D-structure, Reference proteome

Documents

  1. MGD cross-references
    Mouse Genome Database (MGD) cross-references in UniProtKB/Swiss-Prot
  2. PDB cross-references
    Index of Protein Data Bank (PDB) cross-references
UniProt is an ELIXIR core data resource
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