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Protein

39S ribosomal protein L19, mitochondrial

Gene

Mrpl19

Organism
Mus musculus (Mouse)
Status
Reviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

  • structural constituent of ribosome Source: GO_Central

GO - Biological processi

Keywordsi

Molecular functionRibonucleoprotein, Ribosomal protein

Enzyme and pathway databases

ReactomeiR-MMU-5389840 Mitochondrial translation elongation
R-MMU-5419276 Mitochondrial translation termination

Names & Taxonomyi

Protein namesi
Recommended name:
39S ribosomal protein L19, mitochondrial
Short name:
L19mt
Short name:
MRP-L19
Gene namesi
Name:Mrpl19
OrganismiMus musculus (Mouse)
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeMusMus
Proteomesi
  • UP000000589 Componenti: Chromosome 6

Organism-specific databases

MGIiMGI:1926274 Mrpl19

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

Mitochondrion

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_0000030474? – 29239S ribosomal protein L19, mitochondrial
Transit peptidei1 – ?MitochondrionSequence analysis

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Modified residuei77PhosphoserineBy similarity1

Keywords - PTMi

Phosphoprotein

Proteomic databases

EPDiQ9D338
MaxQBiQ9D338
PaxDbiQ9D338
PeptideAtlasiQ9D338
PRIDEiQ9D338

PTM databases

iPTMnetiQ9D338
PhosphoSitePlusiQ9D338

Expressioni

Gene expression databases

BgeeiENSMUSG00000030045 Expressed in 261 organ(s), highest expression level in metanephric loop of Henle
CleanExiMM_MRPL19
GenevisibleiQ9D338 MM

Interactioni

Subunit structurei

Component of the mitochondrial ribosome large subunit (39S) which comprises a 16S rRNA and about 50 distinct proteins.By similarity

Protein-protein interaction databases

BioGridi207876, 1 interactor
STRINGi10090.ENSMUSP00000032124

Structurei

3D structure databases

ProteinModelPortaliQ9D338
SMRiQ9D338
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Keywords - Domaini

Transit peptide

Phylogenomic databases

eggNOGiKOG1698 Eukaryota
COG0335 LUCA
GeneTreeiENSGT00390000009415
HOVERGENiHBG023932
InParanoidiQ9D338
KOiK02884
OMAiYRFIYPE
OrthoDBiEOG091G0O6E
PhylomeDBiQ9D338
TreeFamiTF320270

Family and domain databases

Gene3Di2.30.30.790, 1 hit
InterProiView protein in InterPro
IPR038657 L19_sf
IPR001857 Ribosomal_L19
IPR008991 Translation_prot_SH3-like_sf
PANTHERiPTHR15680 PTHR15680, 1 hit
PfamiView protein in Pfam
PF01245 Ribosomal_L19, 1 hit
PRINTSiPR00061 RIBOSOMALL19
SUPFAMiSSF50104 SSF50104, 1 hit

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

Q9D338-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MAASMAESCR ASLYLARSVR MARPRLAAFA SDACRVCTGP SRFQSTGPSE
60 70 80 90 100
PGGFKPPPKP VIVDRRRVPE DERRFLSPEF IPPRGRTNPL KFKIERKDML
110 120 130 140 150
DRRKVLPIPE FYVGSILRVT TADPYASGKT SQFLGICIKR SGNGLGATFT
160 170 180 190 200
LRNTIEGQGV EICFELYNPR IQEIQVVKLE KRLDDNLLYL RDALPEYSTF
210 220 230 240 250
DVNMKPVPQE ACQEVPVNKL KVKMKPKPWS KRWERPNFNI KGIRFDLALT
260 270 280 290
EEQMKEAQKW NKPWIEFDMM REYDTSKIEA ALWEEIEASK KS
Length:292
Mass (Da):33,578
Last modified:June 1, 2001 - v1
Checksum:i2D85C99D97A59BF5
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK018508 mRNA Translation: BAB31245.1
AK050637 mRNA Translation: BAC34357.1
BC020315 mRNA Translation: AAH20315.1
BC043921 mRNA Translation: AAH43921.1
CCDSiCCDS39523.1
RefSeqiNP_080766.1, NM_026490.2
UniGeneiMm.276293

Genome annotation databases

EnsembliENSMUST00000032124; ENSMUSP00000032124; ENSMUSG00000030045
GeneIDi56284
KEGGimmu:56284
UCSCiuc009clf.2 mouse

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK018508 mRNA Translation: BAB31245.1
AK050637 mRNA Translation: BAC34357.1
BC020315 mRNA Translation: AAH20315.1
BC043921 mRNA Translation: AAH43921.1
CCDSiCCDS39523.1
RefSeqiNP_080766.1, NM_026490.2
UniGeneiMm.276293

3D structure databases

ProteinModelPortaliQ9D338
SMRiQ9D338
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi207876, 1 interactor
STRINGi10090.ENSMUSP00000032124

PTM databases

iPTMnetiQ9D338
PhosphoSitePlusiQ9D338

Proteomic databases

EPDiQ9D338
MaxQBiQ9D338
PaxDbiQ9D338
PeptideAtlasiQ9D338
PRIDEiQ9D338

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSMUST00000032124; ENSMUSP00000032124; ENSMUSG00000030045
GeneIDi56284
KEGGimmu:56284
UCSCiuc009clf.2 mouse

Organism-specific databases

CTDi9801
MGIiMGI:1926274 Mrpl19

Phylogenomic databases

eggNOGiKOG1698 Eukaryota
COG0335 LUCA
GeneTreeiENSGT00390000009415
HOVERGENiHBG023932
InParanoidiQ9D338
KOiK02884
OMAiYRFIYPE
OrthoDBiEOG091G0O6E
PhylomeDBiQ9D338
TreeFamiTF320270

Enzyme and pathway databases

ReactomeiR-MMU-5389840 Mitochondrial translation elongation
R-MMU-5419276 Mitochondrial translation termination

Miscellaneous databases

ChiTaRSiMrpl19 mouse
PROiPR:Q9D338
SOURCEiSearch...

Gene expression databases

BgeeiENSMUSG00000030045 Expressed in 261 organ(s), highest expression level in metanephric loop of Henle
CleanExiMM_MRPL19
GenevisibleiQ9D338 MM

Family and domain databases

Gene3Di2.30.30.790, 1 hit
InterProiView protein in InterPro
IPR038657 L19_sf
IPR001857 Ribosomal_L19
IPR008991 Translation_prot_SH3-like_sf
PANTHERiPTHR15680 PTHR15680, 1 hit
PfamiView protein in Pfam
PF01245 Ribosomal_L19, 1 hit
PRINTSiPR00061 RIBOSOMALL19
SUPFAMiSSF50104 SSF50104, 1 hit
ProtoNetiSearch...

Entry informationi

Entry nameiRM19_MOUSE
AccessioniPrimary (citable) accession number: Q9D338
Secondary accession number(s): Q543I0, Q8R1R0
Entry historyiIntegrated into UniProtKB/Swiss-Prot: July 26, 2002
Last sequence update: June 1, 2001
Last modified: November 7, 2018
This is version 121 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families
  2. Ribosomal proteins
    Ribosomal proteins families and list of entries
  3. MGD cross-references
    Mouse Genome Database (MGD) cross-references in UniProtKB/Swiss-Prot
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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