Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein

Sperm acrosome-associated protein 7

Gene

Spaca7

Organism
Mus musculus (Mouse)
Status
Reviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

Involved in fertilization. Seems not to play a direct role in sperm-egg binding or gamete fusion.1 Publication

GO - Molecular functioni

GO - Biological processi

Keywordsi

Biological processFertilization

Names & Taxonomyi

Protein namesi
Recommended name:
Sperm acrosome-associated protein 7Imported
Gene namesi
Name:Spaca7Imported
OrganismiMus musculus (Mouse)
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeMusMus
Proteomesi
  • UP000000589 Componenti: Chromosome 8

Organism-specific databases

MGIiMGI:1925884 Spaca7

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

Cytoplasmic vesicle, Secreted

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Signal peptidei1 – 24Sequence analysisAdd BLAST24
ChainiPRO_000035056925 – 182Sperm acrosome-associated protein 7Add BLAST158

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Glycosylationi40N-linked (GlcNAc...) asparagineSequence analysis1

Keywords - PTMi

Glycoprotein

Proteomic databases

PaxDbiQ9D2S4
PRIDEiQ9D2S4

PTM databases

PhosphoSitePlusiQ9D2S4

Expressioni

Tissue specificityi

Testis-specific (PubMed:22495889, PubMed:24307706). Expressed in zygotene and pachytene spermatocytes, round spermatids, elongating spermatids and spermatozoa (at protein level) (PubMed:22495889, PubMed:24307706). Testis-specific (PubMed:22495889).2 Publications

Gene expression databases

BgeeiENSMUSG00000010435 Expressed in 28 organ(s), highest expression level in testis
ExpressionAtlasiQ9D2S4 baseline and differential
GenevisibleiQ9D2S4 MM

Family & Domainsi

Keywords - Domaini

Signal

Phylogenomic databases

eggNOGiENOG410J5PZ Eukaryota
ENOG411168G LUCA
GeneTreeiENSGT00390000018090
HOVERGENiHBG058480
InParanoidiQ9D2S4
OMAiCCWQETE
OrthoDBiEOG091G0Z0J
PhylomeDBiQ9D2S4
TreeFamiTF338340

Family and domain databases

InterProiView protein in InterPro
IPR029301 SPACA7
PfamiView protein in Pfam
PF15307 SPACA7, 1 hit

Sequence (1+)i

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

This entry has 1 described isoform and 3 potential isoforms that are computationally mapped.iShow all

Q9D2S4-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MAANRGSRTF LSVFLLCCWQ GAELQPIKTT SGPITEGSLN STTENIPEAL
60 70 80 90 100
DEILAQEILE PKTSAVSETS PRPRSSILTT VQTKEINAGI DENYQEEAFE
110 120 130 140 150
NYHEVLENIE HLPTKEESGK NDRSTVANLH DHSSQTKHEP PSSPEGKGSS
160 170 180
NDDVYGKLSV LDKILENIGQ SEGSLELTES IF
Length:182
Mass (Da):19,943
Last modified:June 1, 2001 - v1
Checksum:iEFDC925007409BB5
GO

Computationally mapped potential isoform sequencesi

There are 3 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
I6L9C9I6L9C9_MOUSE
1700094C09Rik protein
Spaca7 1700094C09Rik
166Annotation score:
A0A1B0GRZ1A0A1B0GRZ1_MOUSE
Sperm acrosome-associated protein 7
Spaca7
158Annotation score:
A0A1B0GRI6A0A1B0GRI6_MOUSE
Sperm acrosome-associated protein 7
Spaca7
57Annotation score:

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK018926 mRNA Translation: BAB31486.1
CCDSiCCDS40222.1
RefSeqiNP_077241.1, NM_024279.2
UniGeneiMm.116871

Genome annotation databases

EnsembliENSMUST00000010579; ENSMUSP00000010579; ENSMUSG00000010435
GeneIDi78634
KEGGimmu:78634
UCSCiuc009kwc.1 mouse

Similar proteinsi

Entry informationi

Entry nameiSPAC7_MOUSE
AccessioniPrimary (citable) accession number: Q9D2S4
Entry historyiIntegrated into UniProtKB/Swiss-Prot: September 23, 2008
Last sequence update: June 1, 2001
Last modified: September 12, 2018
This is version 85 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

We'd like to inform you that we have updated our Privacy Notice to comply with Europe’s new General Data Protection Regulation (GDPR) that applies since 25 May 2018.

Do not show this banner again