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Protein

28S ribosomal protein S33, mitochondrial

Gene

Mrps33

Organism
Mus musculus (Mouse)
Status
Reviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

Keywordsi

Molecular functionRibonucleoprotein, Ribosomal protein

Enzyme and pathway databases

ReactomeiR-MMU-5389840 Mitochondrial translation elongation
R-MMU-5419276 Mitochondrial translation termination

Names & Taxonomyi

Protein namesi
Recommended name:
28S ribosomal protein S33, mitochondrial
Short name:
MRP-S33
Short name:
S33mt
Alternative name(s):
Ganglioside-induced differentiation-associated-protein 3
Gene namesi
Name:Mrps33
Synonyms:Gdap3
OrganismiMus musculus (Mouse)
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeMusMus
Proteomesi
  • UP000000589 Componenti: Chromosome 6

Organism-specific databases

MGIiMGI:1338046 Mrps33

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

Mitochondrion

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Initiator methionineiRemovedBy similarity
ChainiPRO_00000877282 – 10628S ribosomal protein S33, mitochondrialAdd BLAST105

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Modified residuei2N-acetylserineBy similarity1

Keywords - PTMi

Acetylation

Proteomic databases

EPDiQ9D2R8
MaxQBiQ9D2R8
PaxDbiQ9D2R8
PRIDEiQ9D2R8

PTM databases

iPTMnetiQ9D2R8
PhosphoSitePlusiQ9D2R8

Expressioni

Gene expression databases

BgeeiENSMUSG00000029918 Expressed in 33 organ(s), highest expression level in adult mammalian kidney
CleanExiMM_MRPS33
ExpressionAtlasiQ9D2R8 baseline and differential
GenevisibleiQ9D2R8 MM

Interactioni

Subunit structurei

Component of the mitochondrial ribosome small subunit (28S) which comprises a 12S rRNA and about 30 distinct proteins.By similarity

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000031978

Structurei

3D structure databases

ProteinModelPortaliQ9D2R8
SMRiQ9D2R8
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Phylogenomic databases

eggNOGiKOG4104 Eukaryota
ENOG4111X83 LUCA
GeneTreeiENSGT00390000011401
HOGENOMiHOG000007922
HOVERGENiHBG036129
InParanoidiQ9D2R8
KOiK17411
OMAiKEVYDWY
OrthoDBiEOG091G0Y05
PhylomeDBiQ9D2R8
TreeFamiTF313928

Family and domain databases

InterProiView protein in InterPro
IPR013219 Ribosomal_S27/S33_mit
PANTHERiPTHR13362 PTHR13362, 1 hit
PfamiView protein in Pfam
PF08293 MRP-S33, 1 hit

Sequence (1+)i

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

This entry has 1 described isoform and 1 potential isoform that is computationally mapped.Show allAlign All

Q9D2R8-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MSPLSEYALR MSRLSARIFG EVARSTDSKS MKVVSLFSEQ PLAKKKETYD
60 70 80 90 100
WYPNHNTYFA LMGNLRFLGL YRDEHQDFKD EQRRLKKLRG KGKPRKGEGK

RATKKK
Length:106
Mass (Da):12,459
Last modified:June 1, 2001 - v1
Checksum:i3E2FFA322A0750FB
GO

Computationally mapped potential isoform sequencesi

There is 1 potential isoform mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
Q8R2K5Q8R2K5_MOUSE
28S ribosomal protein S33, mitochon...
Mrps33 mCG_4664
34Annotation score:

Sequence cautioni

The sequence CAA76895 differs from that shown. Reason: Erroneous initiation.Curated

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Sequence conflicti13R → L in CAA76895 (PubMed:10217254).Curated1
Sequence conflicti96K → R in CAA76895 (PubMed:10217254).Curated1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
Y17852 mRNA Translation: CAA76895.1 Different initiation.
AK019000 mRNA Translation: BAB31503.1
CCDSiCCDS20026.1
RefSeqiNP_034400.1, NM_010270.2
UniGeneiMm.377071

Genome annotation databases

EnsembliENSMUST00000031978; ENSMUSP00000031978; ENSMUSG00000029918
GeneIDi14548
KEGGimmu:14548
UCSCiuc009bmi.2 mouse

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
Y17852 mRNA Translation: CAA76895.1 Different initiation.
AK019000 mRNA Translation: BAB31503.1
CCDSiCCDS20026.1
RefSeqiNP_034400.1, NM_010270.2
UniGeneiMm.377071

3D structure databases

ProteinModelPortaliQ9D2R8
SMRiQ9D2R8
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000031978

PTM databases

iPTMnetiQ9D2R8
PhosphoSitePlusiQ9D2R8

Proteomic databases

EPDiQ9D2R8
MaxQBiQ9D2R8
PaxDbiQ9D2R8
PRIDEiQ9D2R8

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSMUST00000031978; ENSMUSP00000031978; ENSMUSG00000029918
GeneIDi14548
KEGGimmu:14548
UCSCiuc009bmi.2 mouse

Organism-specific databases

CTDi51650
MGIiMGI:1338046 Mrps33

Phylogenomic databases

eggNOGiKOG4104 Eukaryota
ENOG4111X83 LUCA
GeneTreeiENSGT00390000011401
HOGENOMiHOG000007922
HOVERGENiHBG036129
InParanoidiQ9D2R8
KOiK17411
OMAiKEVYDWY
OrthoDBiEOG091G0Y05
PhylomeDBiQ9D2R8
TreeFamiTF313928

Enzyme and pathway databases

ReactomeiR-MMU-5389840 Mitochondrial translation elongation
R-MMU-5419276 Mitochondrial translation termination

Miscellaneous databases

PROiPR:Q9D2R8
SOURCEiSearch...

Gene expression databases

BgeeiENSMUSG00000029918 Expressed in 33 organ(s), highest expression level in adult mammalian kidney
CleanExiMM_MRPS33
ExpressionAtlasiQ9D2R8 baseline and differential
GenevisibleiQ9D2R8 MM

Family and domain databases

InterProiView protein in InterPro
IPR013219 Ribosomal_S27/S33_mit
PANTHERiPTHR13362 PTHR13362, 1 hit
PfamiView protein in Pfam
PF08293 MRP-S33, 1 hit
ProtoNetiSearch...

Entry informationi

Entry nameiRT33_MOUSE
AccessioniPrimary (citable) accession number: Q9D2R8
Secondary accession number(s): O88743
Entry historyiIntegrated into UniProtKB/Swiss-Prot: October 19, 2002
Last sequence update: June 1, 2001
Last modified: September 12, 2018
This is version 102 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families
  2. Ribosomal proteins
    Ribosomal proteins families and list of entries
  3. MGD cross-references
    Mouse Genome Database (MGD) cross-references in UniProtKB/Swiss-Prot
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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