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Protein

39S ribosomal protein L28, mitochondrial

Gene

Mrpl28

Organism
Mus musculus (Mouse)
Status
Reviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

  • structural constituent of ribosome Source: GO_Central

Keywordsi

Molecular functionRibonucleoprotein, Ribosomal protein

Enzyme and pathway databases

ReactomeiR-MMU-5389840 Mitochondrial translation elongation
R-MMU-5419276 Mitochondrial translation termination

Names & Taxonomyi

Protein namesi
Recommended name:
39S ribosomal protein L28, mitochondrial
Short name:
L28mt
Short name:
MRP-L28
Gene namesi
Name:Mrpl28
OrganismiMus musculus (Mouse)
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeMusMus
Proteomesi
  • UP000000589 Componenti: Chromosome 17

Organism-specific databases

MGIiMGI:1915861 Mrpl28

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

Mitochondrion

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transit peptidei1 – 55MitochondrionBy similarityAdd BLAST55
ChainiPRO_000003050756 – 25739S ribosomal protein L28, mitochondrialAdd BLAST202

Proteomic databases

EPDiQ9D1B9
MaxQBiQ9D1B9
PaxDbiQ9D1B9
PeptideAtlasiQ9D1B9
PRIDEiQ9D1B9

PTM databases

iPTMnetiQ9D1B9
PhosphoSitePlusiQ9D1B9

Expressioni

Gene expression databases

BgeeiENSMUSG00000024181 Expressed in 288 organ(s), highest expression level in cardiac muscle of left ventricle
CleanExiMM_MRPL28
ExpressionAtlasiQ9D1B9 baseline and differential
GenevisibleiQ9D1B9 MM

Interactioni

Subunit structurei

Component of the mitochondrial ribosome large subunit (39S) which comprises a 16S rRNA and about 50 distinct proteins. Interacts with OXA1L.By similarity

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000025014

Structurei

3D structure databases

ProteinModelPortaliQ9D1B9
SMRiQ9D1B9
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Keywords - Domaini

Transit peptide

Phylogenomic databases

eggNOGiKOG3279 Eukaryota
ENOG410XQHX LUCA
GeneTreeiENSGT00390000017359
HOGENOMiHOG000010298
HOVERGENiHBG083707
InParanoidiQ9D1B9
KOiK02902
OMAiWVGLTLE
OrthoDBiEOG091G0IF3
PhylomeDBiQ9D1B9
TreeFamiTF313040

Family and domain databases

Gene3Di2.30.170.40, 1 hit
InterProiView protein in InterPro
IPR034704 L28p-like
IPR026569 Ribo_L28/L24
IPR037147 Ribo_L28/L24_sf
PANTHERiPTHR13528 PTHR13528, 1 hit
PfamiView protein in Pfam
PF00830 Ribosomal_L28, 1 hit
SUPFAMiSSF143800 SSF143800, 1 hit

Sequence (1+)i

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

This entry has 1 described isoform and 1 potential isoform that is computationally mapped.Show allAlign All

Q9D1B9-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MPLHRYPVHL WQKLRLRQGI CARLPAHFLR SLEEERTPTP VHYKPHGTKF
60 70 80 90 100
KINPKNGQRE RVEDVPIPVH YPPESQQGLW GGEGLILGYR YANNDKLSKR
110 120 130 140 150
VKKVWKPQLF TRELYSEILD KKFTVTVTMR TLDLIDEAYG FDFYILKTPK
160 170 180 190 200
EDLGSKFGMD LKRGMLLRLA RQDPHLHPEN PERRAAIYDK YRSFVIPEAE
210 220 230 240 250
AEWVGLTLEE ALEKQRLLEE KDPVPLFKVY VEELVQRLQE QVLSRPAVVQ

KRAGDHA
Length:257
Mass (Da):30,170
Last modified:January 24, 2006 - v3
Checksum:iC011BF7EF537996C
GO

Computationally mapped potential isoform sequencesi

There is 1 potential isoform mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
F6U4U1F6U4U1_MOUSE
39S ribosomal protein L28, mitochon...
Mrpl28
50Annotation score:

Sequence cautioni

The sequence AAH02293 differs from that shown. Reason: Erroneous initiation.Curated
The sequence AAH05797 differs from that shown. Reason: Erroneous initiation.Curated
The sequence AAH80753 differs from that shown. Reason: Erroneous initiation.Curated
The sequence AAI00323 differs from that shown. Reason: Erroneous initiation.Curated
The sequence BAB22962 differs from that shown. Reason: Erroneous initiation.Curated
The sequence BAC27521 differs from that shown. Reason: Erroneous initiation.Curated
The sequence BAC32780 differs from that shown. Reason: Erroneous initiation.Curated

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK003727 mRNA Translation: BAB22962.2 Different initiation.
AK031701 mRNA Translation: BAC27521.1 Different initiation.
AK046544 mRNA Translation: BAC32780.1 Different initiation.
AK163190 mRNA Translation: BAE37227.1
BC002293 mRNA Translation: AAH02293.2 Different initiation.
BC005797 mRNA Translation: AAH05797.2 Different initiation.
BC080753 mRNA Translation: AAH80753.1 Different initiation.
BC100322 mRNA Translation: AAI00323.1 Different initiation.
BC145680 mRNA Translation: AAI45681.1
BC145682 mRNA Translation: AAI45683.1
CCDSiCCDS37509.1
RefSeqiNP_077189.2, NM_024227.3
UniGeneiMm.273102

Genome annotation databases

EnsembliENSMUST00000025014; ENSMUSP00000025014; ENSMUSG00000024181
GeneIDi68611
KEGGimmu:68611
UCSCiuc008bdl.2 mouse

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK003727 mRNA Translation: BAB22962.2 Different initiation.
AK031701 mRNA Translation: BAC27521.1 Different initiation.
AK046544 mRNA Translation: BAC32780.1 Different initiation.
AK163190 mRNA Translation: BAE37227.1
BC002293 mRNA Translation: AAH02293.2 Different initiation.
BC005797 mRNA Translation: AAH05797.2 Different initiation.
BC080753 mRNA Translation: AAH80753.1 Different initiation.
BC100322 mRNA Translation: AAI00323.1 Different initiation.
BC145680 mRNA Translation: AAI45681.1
BC145682 mRNA Translation: AAI45683.1
CCDSiCCDS37509.1
RefSeqiNP_077189.2, NM_024227.3
UniGeneiMm.273102

3D structure databases

ProteinModelPortaliQ9D1B9
SMRiQ9D1B9
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000025014

PTM databases

iPTMnetiQ9D1B9
PhosphoSitePlusiQ9D1B9

Proteomic databases

EPDiQ9D1B9
MaxQBiQ9D1B9
PaxDbiQ9D1B9
PeptideAtlasiQ9D1B9
PRIDEiQ9D1B9

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSMUST00000025014; ENSMUSP00000025014; ENSMUSG00000024181
GeneIDi68611
KEGGimmu:68611
UCSCiuc008bdl.2 mouse

Organism-specific databases

CTDi10573
MGIiMGI:1915861 Mrpl28

Phylogenomic databases

eggNOGiKOG3279 Eukaryota
ENOG410XQHX LUCA
GeneTreeiENSGT00390000017359
HOGENOMiHOG000010298
HOVERGENiHBG083707
InParanoidiQ9D1B9
KOiK02902
OMAiWVGLTLE
OrthoDBiEOG091G0IF3
PhylomeDBiQ9D1B9
TreeFamiTF313040

Enzyme and pathway databases

ReactomeiR-MMU-5389840 Mitochondrial translation elongation
R-MMU-5419276 Mitochondrial translation termination

Miscellaneous databases

PROiPR:Q9D1B9
SOURCEiSearch...

Gene expression databases

BgeeiENSMUSG00000024181 Expressed in 288 organ(s), highest expression level in cardiac muscle of left ventricle
CleanExiMM_MRPL28
ExpressionAtlasiQ9D1B9 baseline and differential
GenevisibleiQ9D1B9 MM

Family and domain databases

Gene3Di2.30.170.40, 1 hit
InterProiView protein in InterPro
IPR034704 L28p-like
IPR026569 Ribo_L28/L24
IPR037147 Ribo_L28/L24_sf
PANTHERiPTHR13528 PTHR13528, 1 hit
PfamiView protein in Pfam
PF00830 Ribosomal_L28, 1 hit
SUPFAMiSSF143800 SSF143800, 1 hit
ProtoNetiSearch...

Entry informationi

Entry nameiRM28_MOUSE
AccessioniPrimary (citable) accession number: Q9D1B9
Secondary accession number(s): A6H5Y0
, Q3TR04, Q497Y8, Q66JU7
Entry historyiIntegrated into UniProtKB/Swiss-Prot: September 19, 2003
Last sequence update: January 24, 2006
Last modified: November 7, 2018
This is version 122 of the entry and version 3 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families
  2. Ribosomal proteins
    Ribosomal proteins families and list of entries
  3. MGD cross-references
    Mouse Genome Database (MGD) cross-references in UniProtKB/Swiss-Prot
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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