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Protein

Glutamine amidotransferase-like class 1 domain-containing protein 3A, mitochondrial

Gene

Gatd3a

Organism
Mus musculus (Mouse)
Status
Reviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

May play a role in promoting mitochondrial enlargement in cone photoreceptor cells.By similarity

Names & Taxonomyi

Protein namesi
Recommended name:
Glutamine amidotransferase-like class 1 domain-containing protein 3A, mitochondrialCurated
Alternative name(s):
ES1 protein homolog, mitochondrialCurated
Gene namesi
Name:Gatd3aBy similarity
Synonyms:D10Jhu81e
OrganismiMus musculus (Mouse)
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeMusMus
Proteomesi
  • UP000000589 Componenti: Chromosome 10

Organism-specific databases

MGIiMGI:1351861 D10Jhu81e

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

Mitochondrion

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transit peptidei1 – 39MitochondrionBy similarityAdd BLAST39
ChainiPRO_000000854540 – 266Glutamine amidotransferase-like class 1 domain-containing protein 3A, mitochondrialAdd BLAST227

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Modified residuei149N6-acetyllysineCombined sources1
Modified residuei155N6-acetyllysineCombined sources1
Modified residuei162N6-acetyllysineCombined sources1
Modified residuei201N6-acetyllysine; alternateCombined sources1
Modified residuei201N6-succinyllysine; alternateCombined sources1
Modified residuei217N6-acetyllysineCombined sources1
Modified residuei221N6-acetyllysine; alternateCombined sources1
Modified residuei221N6-succinyllysine; alternateCombined sources1
Modified residuei231N6-acetyllysine; alternateCombined sources1
Modified residuei231N6-succinyllysine; alternateCombined sources1

Keywords - PTMi

Acetylation

Proteomic databases

EPDiQ9D172
MaxQBiQ9D172
PaxDbiQ9D172
PeptideAtlasiQ9D172
PRIDEiQ9D172

2D gel databases

REPRODUCTION-2DPAGEiQ9D172

PTM databases

iPTMnetiQ9D172
PhosphoSitePlusiQ9D172
SwissPalmiQ9D172

Expressioni

Gene expression databases

BgeeiENSMUSG00000053329
ExpressionAtlasiQ9D172 baseline and differential
GenevisibleiQ9D172 MM

Interactioni

Protein-protein interaction databases

BioGridi205883, 1 interactor
IntActiQ9D172, 4 interactors
MINTiQ9D172
STRINGi10090.ENSMUSP00000001242

Structurei

3D structure databases

ProteinModelPortaliQ9D172
SMRiQ9D172
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the GATD3 family.Curated

Keywords - Domaini

Transit peptide

Phylogenomic databases

eggNOGiENOG410IH62 Eukaryota
COG3155 LUCA
GeneTreeiENSGT00390000003706
HOGENOMiHOG000269874
HOVERGENiHBG001844
InParanoidiQ9D172
OMAiAQVQCFA
OrthoDBiEOG091G0KUH
PhylomeDBiQ9D172
TreeFamiTF329408

Family and domain databases

Gene3Di3.40.50.880, 1 hit
InterProiView protein in InterPro
IPR029062 Class_I_gatase-like
SUPFAMiSSF52317 SSF52317, 1 hit

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

Q9D172-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MAAVRVLVAP RLASALLPLS RYHRAPSQRA ALHSSAPRPG ARVALVLSGC
60 70 80 90 100
GVYDGTEIHE ASAILVHLSR GGAEVQIFAP DVPQMHVIDH TKGEPSERES
110 120 130 140 150
RNVLAESARI ARGKITSLAQ LNAANHDAAI FPGGFGAAKN LSTFAVDGKD
160 170 180 190 200
CKVNKEVERV LKEFHGAKKP IGLCCIAPVL AAKVIKGVEV TVGHEQEEGG
210 220 230 240 250
KWPYAGTAEA IKALGAKHCV KGVTEAHVDQ KNKVVTTPAF MCETALHHIH
260
DGIGAMVKNV LELTGK
Length:266
Mass (Da):28,090
Last modified:June 1, 2001 - v1
Checksum:i9F311AD7288F4C2B
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK003866 mRNA Translation: BAB23047.1
BC013475 mRNA Translation: AAH13475.1
CCDSiCCDS35957.1
RefSeqiNP_613067.1, NM_138601.2
UniGeneiMm.268691

Genome annotation databases

EnsembliENSMUST00000001242; ENSMUSP00000001242; ENSMUSG00000053329
GeneIDi28295
KEGGimmu:28295
UCSCiuc007fxj.1 mouse

Similar proteinsi

Entry informationi

Entry nameiGAL3A_MOUSE
AccessioniPrimary (citable) accession number: Q9D172
Entry historyiIntegrated into UniProtKB/Swiss-Prot: September 27, 2004
Last sequence update: June 1, 2001
Last modified: July 18, 2018
This is version 113 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Direct protein sequencing, Reference proteome

Documents

  1. MGD cross-references
    Mouse Genome Database (MGD) cross-references in UniProtKB/Swiss-Prot
  2. SIMILARITY comments
    Index of protein domains and families

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