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Protein

UPF0686 protein C11orf1 homolog

Gene
N/A
Organism
Mus musculus (Mouse)
Status
Reviewed-Annotation score: -Experimental evidence at transcript leveli

Names & Taxonomyi

Protein namesi
Recommended name:
UPF0686 protein C11orf1 homolog
OrganismiMus musculus (Mouse)
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeMusMus
Proteomesi
  • UP000000589 Componenti: Chromosome 9

Organism-specific databases

MGIiMGI:1915971 1110032A03Rik

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

Nucleus

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00000898301 – 166UPF0686 protein C11orf1 homologAdd BLAST166

Proteomic databases

PaxDbiQ9D131
PRIDEiQ9D131

PTM databases

iPTMnetiQ9D131
PhosphoSitePlusiQ9D131

Expressioni

Gene expression databases

BgeeiENSMUSG00000037971 Expressed in 288 organ(s), highest expression level in retina
CleanExiMM_1110032A03RIK
ExpressionAtlasiQ9D131 baseline and differential
GenevisibleiQ9D131 MM

Interactioni

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000041803

Structurei

3D structure databases

SMRiQ9D131
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the UPF0686 family.Curated

Phylogenomic databases

eggNOGiENOG410IVWW Eukaryota
ENOG411205M LUCA
GeneTreeiENSGT00390000002905
HOVERGENiHBG050969
InParanoidiQ9D131
OMAiNENAYSN
OrthoDBiEOG091G0ZSB
PhylomeDBiQ9D131
TreeFamiTF329225

Family and domain databases

InterProiView protein in InterPro
IPR009524 UPF0686
PANTHERiPTHR34524 PTHR34524, 1 hit
PfamiView protein in Pfam
PF06608 DUF1143, 1 hit

Sequences (2+)i

Sequence statusi: Complete.

This entry describes 2 isoformsi produced by alternative splicing. AlignAdd to basket

This entry has 2 described isoforms and 2 potential isoforms that are computationally mapped.Show allAlign All

Isoform 1 (identifier: Q9D131-1) [UniParc]FASTAAdd to basket

This isoform has been chosen as the 'canonical' sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

« Hide
        10         20         30         40         50
MAVSCSLNHS TYLQRQNLVC YLRNPHYGSL IYADGHGEVW TDWNDMSKFL
60 70 80 90 100
QYGWRCTTNE NSYSNRTLVG NWNQERYDLK NIVKPKPLPS QFGHAFETTY
110 120 130 140 150
DANYSRKKPQ STHRFKREPH WFPGHQPELD PPHYKCTAKS TYMTNYSEPQ
160
PTHYSCCVYD PSVSQS
Length:166
Mass (Da):19,527
Last modified:June 1, 2001 - v1
Checksum:iB299BEE9DB28E0EC
GO
Isoform 2 (identifier: Q9D131-2) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     1-13: MAVSCSLNHSTYL → MELPYRNRFYSLRCSSKSLYSPSSYTSII

Note: No experimental confirmation available.
Show »
Length:182
Mass (Da):21,551
Checksum:iAF5E65013478DA2B
GO

Computationally mapped potential isoform sequencesi

There are 2 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
H3BL73H3BL73_MOUSE
RIKEN cDNA 1110032A03 gene
1110032A03Rik
143Annotation score:
H3BJ69H3BJ69_MOUSE
RIKEN cDNA 1110032A03 gene
1110032A03Rik
89Annotation score:

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Sequence conflicti8N → S in CAB96546 (PubMed:10873569).Curated1
Sequence conflicti8N → S in BAE34519 (PubMed:16141072).Curated1
Sequence conflicti14Q → K in CAB96546 (PubMed:10873569).Curated1
Sequence conflicti14Q → K in BAE34519 (PubMed:16141072).Curated1
Sequence conflicti158V → I in BC032012 (PubMed:15489334).Curated1

Natural variant

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Natural varianti166S → SQGPGI2 Publications1

Alternative sequence

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Alternative sequenceiVSP_0275841 – 13MAVSC…HSTYL → MELPYRNRFYSLRCSSKSLY SPSSYTSII in isoform 2. 1 PublicationAdd BLAST13

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AJ250230 mRNA Translation: CAB96546.1
AK004016 mRNA Translation: BAB23127.1
AK015671 mRNA Translation: BAB29923.1
AK043513 mRNA Translation: BAC31564.1
AK158460 mRNA Translation: BAE34519.1
AK166202 mRNA Translation: BAE38625.1
CT010205 mRNA Translation: CAJ18413.1
BC032012 mRNA No translation available.
CCDSiCCDS23173.1 [Q9D131-1]
CCDS80996.1 [Q9D131-2]
RefSeqiNP_001298002.1, NM_001311073.1 [Q9D131-2]
NP_075972.2, NM_023483.3 [Q9D131-1]
UniGeneiMm.171374
Mm.432356

Genome annotation databases

EnsembliENSMUST00000042468; ENSMUSP00000041803; ENSMUSG00000037971 [Q9D131-1]
ENSMUST00000042576; ENSMUSP00000046890; ENSMUSG00000037971 [Q9D131-2]
GeneIDi68721
KEGGimmu:68721
UCSCiuc009pko.1 mouse [Q9D131-2]
uc009pkp.1 mouse [Q9D131-1]

Keywords - Coding sequence diversityi

Alternative splicing, Polymorphism

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AJ250230 mRNA Translation: CAB96546.1
AK004016 mRNA Translation: BAB23127.1
AK015671 mRNA Translation: BAB29923.1
AK043513 mRNA Translation: BAC31564.1
AK158460 mRNA Translation: BAE34519.1
AK166202 mRNA Translation: BAE38625.1
CT010205 mRNA Translation: CAJ18413.1
BC032012 mRNA No translation available.
CCDSiCCDS23173.1 [Q9D131-1]
CCDS80996.1 [Q9D131-2]
RefSeqiNP_001298002.1, NM_001311073.1 [Q9D131-2]
NP_075972.2, NM_023483.3 [Q9D131-1]
UniGeneiMm.171374
Mm.432356

3D structure databases

SMRiQ9D131
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000041803

PTM databases

iPTMnetiQ9D131
PhosphoSitePlusiQ9D131

Proteomic databases

PaxDbiQ9D131
PRIDEiQ9D131

Protocols and materials databases

DNASUi68721
Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSMUST00000042468; ENSMUSP00000041803; ENSMUSG00000037971 [Q9D131-1]
ENSMUST00000042576; ENSMUSP00000046890; ENSMUSG00000037971 [Q9D131-2]
GeneIDi68721
KEGGimmu:68721
UCSCiuc009pko.1 mouse [Q9D131-2]
uc009pkp.1 mouse [Q9D131-1]

Organism-specific databases

MGIiMGI:1915971 1110032A03Rik

Phylogenomic databases

eggNOGiENOG410IVWW Eukaryota
ENOG411205M LUCA
GeneTreeiENSGT00390000002905
HOVERGENiHBG050969
InParanoidiQ9D131
OMAiNENAYSN
OrthoDBiEOG091G0ZSB
PhylomeDBiQ9D131
TreeFamiTF329225

Miscellaneous databases

PROiPR:Q9D131

Gene expression databases

BgeeiENSMUSG00000037971 Expressed in 288 organ(s), highest expression level in retina
CleanExiMM_1110032A03RIK
ExpressionAtlasiQ9D131 baseline and differential
GenevisibleiQ9D131 MM

Family and domain databases

InterProiView protein in InterPro
IPR009524 UPF0686
PANTHERiPTHR34524 PTHR34524, 1 hit
PfamiView protein in Pfam
PF06608 DUF1143, 1 hit
ProtoNetiSearch...

Entry informationi

Entry nameiCK001_MOUSE
AccessioniPrimary (citable) accession number: Q9D131
Secondary accession number(s): Q3TM17
, Q3TYP3, Q4FK47, Q8K0A6, Q9D589, Q9JHT0
Entry historyiIntegrated into UniProtKB/Swiss-Prot: May 24, 2004
Last sequence update: June 1, 2001
Last modified: November 7, 2018
This is version 95 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families
  2. MGD cross-references
    Mouse Genome Database (MGD) cross-references in UniProtKB/Swiss-Prot
  3. Uncharacterized protein families (UPF)
    List of uncharacterized protein family (UPF) entries
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Main funding by: National Institutes of Health

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