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Protein

28S ribosomal protein S25, mitochondrial

Gene

Mrps25

Organism
Mus musculus (Mouse)
Status
Reviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

GO - Biological processi

  • mitochondrial translation Source: MGI

Keywordsi

Molecular functionRibonucleoprotein, Ribosomal protein

Enzyme and pathway databases

ReactomeiR-MMU-5389840 Mitochondrial translation elongation
R-MMU-5419276 Mitochondrial translation termination

Names & Taxonomyi

Protein namesi
Recommended name:
28S ribosomal protein S25, mitochondrial
Short name:
MRP-S25
Short name:
S25mt
Gene namesi
Name:Mrps25
Synonyms:Rpms25
OrganismiMus musculus (Mouse)
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeMusMus
Proteomesi
  • UP000000589 Componenti: Chromosome 6

Organism-specific databases

MGIiMGI:1928140 Mrps25

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

Mitochondrion

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00000877091 – 17128S ribosomal protein S25, mitochondrialAdd BLAST171

Proteomic databases

EPDiQ9D125
MaxQBiQ9D125
PaxDbiQ9D125
PRIDEiQ9D125

PTM databases

iPTMnetiQ9D125
PhosphoSitePlusiQ9D125

Expressioni

Gene expression databases

BgeeiENSMUSG00000014551 Expressed in 288 organ(s), highest expression level in primary oocyte
CleanExiMM_MRPS25
GenevisibleiQ9D125 MM

Interactioni

Subunit structurei

Component of the mitochondrial ribosome small subunit (28S) which comprises a 12S rRNA and about 30 distinct proteins.By similarity

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000114402

Structurei

3D structure databases

ProteinModelPortaliQ9D125
SMRiQ9D125
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Phylogenomic databases

eggNOGiKOG4079 Eukaryota
ENOG410YI66 LUCA
GeneTreeiENSGT00640000091558
HOGENOMiHOG000007270
HOVERGENiHBG002378
InParanoidiQ9D125
KOiK17404
OMAiCMCEVEG
OrthoDBiEOG091G0P9B
PhylomeDBiQ9D125
TreeFamiTF300292

Family and domain databases

InterProiView protein in InterPro
IPR040049 MRPS25
IPR007741 Ribosome/NADH_DH
IPR036249 Thioredoxin-like_sf
PANTHERiPTHR13274 PTHR13274, 1 hit
PfamiView protein in Pfam
PF05047 L51_S25_CI-B8, 1 hit
SMARTiView protein in SMART
SM00916 L51_S25_CI-B8, 1 hit
SUPFAMiSSF52833 SSF52833, 1 hit

Sequencei

Sequence statusi: Complete.

Q9D125-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MPMKGRFPIR RTLQYLGRGD VVFKESVKIM TVNYNTYGEL GEGARKFVFF
60 70 80 90 100
NIPQIQYKNP WVQIMMFKNM TPSPFLRFYL DSGEQVLVDV ETKSNKEIME
110 120 130 140 150
HIKKILGKKE ETLREEELEK QQRFHPGNFG PRKYCLRECM CEVEGQVPCP
160 170
GLVPLPKEMT GKYKAALKAS T
Length:171
Mass (Da):19,920
Last modified:April 27, 2001 - v1
Checksum:iF7CD5B07163FB14A
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Sequence conflicti60P → S in BAB28705 (PubMed:16141072).Curated1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK004037 mRNA Translation: BAB23136.1
AK013196 mRNA Translation: BAB28705.1
BC022953 mRNA Translation: AAH22953.1
CCDSiCCDS20373.1
RefSeqiNP_079854.2, NM_025578.4
UniGeneiMm.476867
Mm.87062

Genome annotation databases

EnsembliENSMUST00000140438; ENSMUSP00000114402; ENSMUSG00000014551
GeneIDi64658
KEGGimmu:64658
UCSCiuc009cyu.1 mouse

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK004037 mRNA Translation: BAB23136.1
AK013196 mRNA Translation: BAB28705.1
BC022953 mRNA Translation: AAH22953.1
CCDSiCCDS20373.1
RefSeqiNP_079854.2, NM_025578.4
UniGeneiMm.476867
Mm.87062

3D structure databases

ProteinModelPortaliQ9D125
SMRiQ9D125
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000114402

PTM databases

iPTMnetiQ9D125
PhosphoSitePlusiQ9D125

Proteomic databases

EPDiQ9D125
MaxQBiQ9D125
PaxDbiQ9D125
PRIDEiQ9D125

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSMUST00000140438; ENSMUSP00000114402; ENSMUSG00000014551
GeneIDi64658
KEGGimmu:64658
UCSCiuc009cyu.1 mouse

Organism-specific databases

CTDi64432
MGIiMGI:1928140 Mrps25

Phylogenomic databases

eggNOGiKOG4079 Eukaryota
ENOG410YI66 LUCA
GeneTreeiENSGT00640000091558
HOGENOMiHOG000007270
HOVERGENiHBG002378
InParanoidiQ9D125
KOiK17404
OMAiCMCEVEG
OrthoDBiEOG091G0P9B
PhylomeDBiQ9D125
TreeFamiTF300292

Enzyme and pathway databases

ReactomeiR-MMU-5389840 Mitochondrial translation elongation
R-MMU-5419276 Mitochondrial translation termination

Miscellaneous databases

PROiPR:Q9D125
SOURCEiSearch...

Gene expression databases

BgeeiENSMUSG00000014551 Expressed in 288 organ(s), highest expression level in primary oocyte
CleanExiMM_MRPS25
GenevisibleiQ9D125 MM

Family and domain databases

InterProiView protein in InterPro
IPR040049 MRPS25
IPR007741 Ribosome/NADH_DH
IPR036249 Thioredoxin-like_sf
PANTHERiPTHR13274 PTHR13274, 1 hit
PfamiView protein in Pfam
PF05047 L51_S25_CI-B8, 1 hit
SMARTiView protein in SMART
SM00916 L51_S25_CI-B8, 1 hit
SUPFAMiSSF52833 SSF52833, 1 hit
ProtoNetiSearch...

Entry informationi

Entry nameiRT25_MOUSE
AccessioniPrimary (citable) accession number: Q9D125
Secondary accession number(s): Q9CYY8
Entry historyiIntegrated into UniProtKB/Swiss-Prot: April 27, 2001
Last sequence update: April 27, 2001
Last modified: November 7, 2018
This is version 125 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Direct protein sequencing, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families
  2. Ribosomal proteins
    Ribosomal proteins families and list of entries
  3. MGD cross-references
    Mouse Genome Database (MGD) cross-references in UniProtKB/Swiss-Prot
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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