Mrps25

Functionⁱ

GO - Molecular functionⁱ

structural constituent of ribosome
Source: MGI
Inferred from sequence orthologyⁱ
- 10938081

View the complete GO annotation on QuickGO ...

GO - Biological processⁱ

mitochondrial translation
Source: MGI
Inferred by curatorⁱ
- 11023686

View the complete GO annotation on QuickGO ...

Keywordsⁱ

Molecular function	Ribonucleoprotein, Ribosomal protein

Molecular function

Ribonucleoprotein, Ribosomal protein

Enzyme and pathway databases

Reactomeⁱ	R-MMU-5389840 Mitochondrial translation elongation R-MMU-5419276 Mitochondrial translation termination

Reactomeⁱ

R-MMU-5389840 Mitochondrial translation elongation
R-MMU-5419276 Mitochondrial translation termination

Names & Taxonomyⁱ

Protein namesⁱ	Recommended name: 28S ribosomal protein S25, mitochondrial Short name: MRP-S25 Short name: S25mt
Gene namesⁱ	Name:Mrps25 Synonyms:Rpms25
Organismⁱ	Mus musculus (Mouse)
Taxonomic identifierⁱ	10090 [NCBI]
Taxonomic lineageⁱ	cellular organisms › Eukaryota › Opisthokonta › Metazoa › Eumetazoa › Bilateria › Deuterostomia › Chordata › Craniata › Vertebrata › Gnathostomata › Teleostomi › Euteleostomi › Sarcopterygii › Dipnotetrapodomorpha › Tetrapoda › Amniota › Mammalia › Theria › Eutheria › Boreoeutheria › Euarchontoglires › Glires › Rodentia › Myomorpha › Muroidea › Muridae › Murinae › Mus › Mus
Proteomesⁱ	UP000000589 Componentⁱ: Chromosome 6

Organism-specific databases

MGIⁱ	MGI:1928140 Mrps25

Keywords - Cellular componentⁱ

Mitochondrion

PTM / Processingⁱ

Molecule processing

Feature key	Position(s)	DescriptionActions	Graphical view	Length
ChainⁱPRO_0000087709	1 – 171	28S ribosomal protein S25, mitochondrialAdd BLAST		171

Proteomic databases

EPDⁱ	Q9D125
MaxQB - The MaxQuant DataBase More...MaxQBⁱ	Q9D125
PaxDbⁱ	Q9D125
PRIDEⁱ	Q9D125

PTM databases

iPTMnetⁱ	Q9D125
PhosphoSitePlusⁱ	Q9D125

Expressionⁱ

Gene expression databases

Bgeeⁱ	ENSMUSG00000014551 Expressed in 288 organ(s), highest expression level in primary oocyte
CleanExⁱ	MM_MRPS25
Genevisibleⁱ	Q9D125 MM

Interactionⁱ

Subunit structureⁱ

Component of the mitochondrial ribosome small subunit (28S) which comprises a 12S rRNA and about 30 distinct proteins.By similarity

Protein-protein interaction databases

STRINGⁱ	10090.ENSMUSP00000114402

STRINGⁱ

10090.ENSMUSP00000114402

Structureⁱ

3D structure databases

ProteinModelPortalⁱ	Q9D125
SMRⁱ	Q9D125
ModBaseⁱ	Search...
MobiDBⁱ	Search...

Family & Domainsⁱ

Sequence similaritiesⁱ

Belongs to the mitochondrion-specific ribosomal protein mS25 family.Curated

Phylogenomic databases

eggNOGⁱ	KOG4079 Eukaryota ENOG410YI66 LUCA
Ensembl GeneTree More...GeneTreeⁱ	ENSGT00640000091558
HOGENOMⁱ	HOG000007270
HOVERGENⁱ	HBG002378
InParanoidⁱ	Q9D125
KEGG Orthology (KO) More...KOⁱ	K17404
OMAⁱ	CMCEVEG
Database of Orthologous Groups More...OrthoDBⁱ	EOG091G0P9B
PhylomeDBⁱ	Q9D125
TreeFamⁱ	TF300292

Family and domain databases

InterProⁱ	View protein in InterPro IPR040049 MRPS25 IPR007741 Ribosome/NADH_DH IPR036249 Thioredoxin-like_sf
PANTHERⁱ	PTHR13274 PTHR13274, 1 hit
Pfam protein domain database More...Pfamⁱ	View protein in Pfam PF05047 L51_S25_CI-B8, 1 hit
SMARTⁱ	View protein in SMART SM00916 L51_S25_CI-B8, 1 hit
SUPFAMⁱ	SSF52833 SSF52833, 1 hit

Sequenceⁱ

Sequence statusⁱ: Complete.

Q9D125-1 [UniParc]FASTA Add to basket

« Hide

        10         20         30         40         50
MPMKGRFPIR RTLQYLGRGD VVFKESVKIM TVNYNTYGEL GEGARKFVFF 
        60         70         80         90        100
NIPQIQYKNP WVQIMMFKNM TPSPFLRFYL DSGEQVLVDV ETKSNKEIME 
       110        120        130        140        150
HIKKILGKKE ETLREEELEK QQRFHPGNFG PRKYCLRECM CEVEGQVPCP 
       160        170 
GLVPLPKEMT GKYKAALKAS T

Length:171

Mass (Da):19,920

Last modified:April 27, 2001 - v1

Checksum:ⁱF7CD5B07163FB14A

GO

Experimental Info

Feature key	Position(s)	DescriptionActions	Graphical view	Length
Sequence conflictⁱ	60	P → S in BAB28705 (PubMed:16141072).Curated		1

Sequence databases

Select the link destinations: EMBLⁱ GenBankⁱ DDBJⁱ Links Updated	AK004037 mRNA Translation: BAB23136.1 AK013196 mRNA Translation: BAB28705.1 BC022953 mRNA Translation: AAH22953.1
The Consensus CDS (CCDS) project More...CCDSⁱ	CCDS20373.1
NCBI Reference Sequences More...RefSeqⁱ	NP_079854.2, NM_025578.4
UniGeneⁱ	Mm.476867 Mm.87062

Genome annotation databases

Ensemblⁱ	ENSMUST00000140438; ENSMUSP00000114402; ENSMUSG00000014551
GeneIDⁱ	64658
KEGGⁱ	mmu:64658
UCSC genome browser More...UCSCⁱ	uc009cyu.1 mouse

Similar proteinsⁱ

100% Identity
90% Identity
50% Identity

Protein	Similar proteins		Species	Score	Length	Source
Q9D125	MFLJ00023 protein (Fragment)		MOUSE		164	UniRef100_Q9D125

Protein	Similar proteins		Species	Score	Length	Source
Q9D125	28S ribosomal protein S25, mitochondrial		RAT		171	UniRef90_Q9D125
MFLJ00023 protein (Fragment)		MOUSE		164
Uncharacterized protein (Fragment)		NEOLE		139
UPI000B4F2B1C		MERUN		171

Protein	Similar proteins		Species	Score	Length	Source
Q9D125	28S ribosomal protein S25, mitochondrial	)	HUMAN		173	UniRef50_P82663
28S ribosomal protein S25, mitochondrial	)	BOVIN		173
28S ribosomal protein S25, mitochondrial		RAT		171
MRPS25 isoform 3		PANTR		173
Uncharacterized protein		PANPA		173
+188

Cross-referencesⁱ

Sequence databases

Select the link destinations: EMBLⁱ GenBankⁱ DDBJⁱ Links Updated	AK004037 mRNA Translation: BAB23136.1 AK013196 mRNA Translation: BAB28705.1 BC022953 mRNA Translation: AAH22953.1
CCDSⁱ	CCDS20373.1
RefSeqⁱ	NP_079854.2, NM_025578.4
UniGeneⁱ	Mm.476867 Mm.87062

3D structure databases

ProteinModelPortalⁱ	Q9D125
SMRⁱ	Q9D125
ModBaseⁱ	Search...
MobiDBⁱ	Search...

Protein-protein interaction databases

STRINGⁱ	10090.ENSMUSP00000114402

STRINGⁱ

10090.ENSMUSP00000114402

PTM databases

iPTMnetⁱ	Q9D125
PhosphoSitePlusⁱ	Q9D125

Proteomic databases

EPDⁱ	Q9D125
MaxQBⁱ	Q9D125
PaxDbⁱ	Q9D125
PRIDEⁱ	Q9D125

Protocols and materials databases

Structural Biology Knowledgebase	Search...

Structural Biology Knowledgebase

Search...

Genome annotation databases

Ensemblⁱ	ENSMUST00000140438; ENSMUSP00000114402; ENSMUSG00000014551
GeneIDⁱ	64658
KEGGⁱ	mmu:64658
UCSCⁱ	uc009cyu.1 mouse

Organism-specific databases

CTDⁱ	64432
MGIⁱ	MGI:1928140 Mrps25

Phylogenomic databases

eggNOGⁱ	KOG4079 Eukaryota ENOG410YI66 LUCA
GeneTreeⁱ	ENSGT00640000091558
HOGENOMⁱ	HOG000007270
HOVERGENⁱ	HBG002378
InParanoidⁱ	Q9D125
KOⁱ	K17404
OMAⁱ	CMCEVEG
OrthoDBⁱ	EOG091G0P9B
PhylomeDBⁱ	Q9D125
TreeFamⁱ	TF300292

Enzyme and pathway databases

Reactomeⁱ	R-MMU-5389840 Mitochondrial translation elongation R-MMU-5419276 Mitochondrial translation termination

Reactomeⁱ

R-MMU-5389840 Mitochondrial translation elongation
R-MMU-5419276 Mitochondrial translation termination

Miscellaneous databases

Protein Ontology More...PROⁱ	PR:Q9D125
SOURCEⁱ	Search...

Gene expression databases

Bgeeⁱ	ENSMUSG00000014551 Expressed in 288 organ(s), highest expression level in primary oocyte
CleanExⁱ	MM_MRPS25
Genevisibleⁱ	Q9D125 MM

Family and domain databases

InterProⁱ	View protein in InterPro IPR040049 MRPS25 IPR007741 Ribosome/NADH_DH IPR036249 Thioredoxin-like_sf
PANTHERⁱ	PTHR13274 PTHR13274, 1 hit
Pfamⁱ	View protein in Pfam PF05047 L51_S25_CI-B8, 1 hit
SMARTⁱ	View protein in SMART SM00916 L51_S25_CI-B8, 1 hit
SUPFAMⁱ	SSF52833 SSF52833, 1 hit
ProtoNetⁱ	Search...

Entry informationⁱ

Entry nameⁱ	RT25_MOUSE
Accessionⁱ	Q9D125Primary (citable) accession number: Q9D125 Secondary accession number(s): Q9CYY8
Entry historyⁱ	Integrated into UniProtKB/Swiss-Prot:	April 27, 2001
	Last sequence update:	April 27, 2001
	Last modified:	November 7, 2018
	This is version 125 of the entry and version 1 of the sequence. See complete history.
Entry statusⁱ	Reviewed (UniProtKB/Swiss-Prot)
Annotation program	Chordata Protein Annotation Program

Miscellaneousⁱ

Keywords - Technical termⁱ

Complete proteome, Direct protein sequencing, Reference proteome

Documents

SIMILARITY comments
Index of protein domains and families
Ribosomal proteins
Ribosomal proteins families and list of entries
MGD cross-references
Mouse Genome Database (MGD) cross-references in UniProtKB/Swiss-Prot

UniProtKB

UniParc

Help

UniRef

Proteomes

Annotation systems

Supporting data

UniProtKB - Q9D125 (RT25_MOUSE)

Your basket is currently empty. i <p>When browsing through different UniProt proteins, you can use the ‘basket’ to save them, so that you can back to find or analyse them later.<p><a href='/help/basket' target='_top'>More...</a></p>

28S ribosomal protein S25, mitochondrial

Select a section on the left to see content.

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

GO - Biological processi

Enzyme and pathway databases

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

Organism-specific databases

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Mitochondrion

Mitochondrion

Keywords - Cellular componenti

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Proteomic databases

PTM databases

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

Protein-protein interaction databases

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

<p>This subsection of the ‘Family and domains’ section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Phylogenomic databases

Family and domain databases

Experimental Info

Sequence databases

Genome annotation databases

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

3D structure databases

Protein-protein interaction databases

PTM databases

Proteomic databases

Protocols and materials databases

Genome annotation databases

Organism-specific databases

Phylogenomic databases

Enzyme and pathway databases

Miscellaneous databases

Gene expression databases

Family and domain databases

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Documents

UniProt is an ELIXIR core data resource

Your basket is currently empty. ⁱ

Functionⁱ

GO - Molecular functionⁱ

GO - Biological processⁱ

Names & Taxonomyⁱ

Subcellular locationⁱ

Keywords - Cellular componentⁱ

PTM / Processingⁱ

Expressionⁱ

Interactionⁱ

Structureⁱ

Family & Domainsⁱ

Sequence similaritiesⁱ

Cross-referencesⁱ

Entry informationⁱ

Miscellaneousⁱ

Keywords - Technical termⁱ