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Protein

Parathymosin

Gene

Ptms

Organism
Mus musculus (Mouse)
Status
Reviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

Parathymosin may mediate immune function by blocking the effect of prothymosin alpha which confers resistance to certain opportunistic infections.By similarity

GO - Molecular functioni

GO - Biological processi

Keywordsi

Biological processImmunity

Names & Taxonomyi

Protein namesi
Recommended name:
Parathymosin
Gene namesi
Name:Ptms
OrganismiMus musculus (Mouse)
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeMusMus
Proteomesi
  • UP000000589 Componenti: Chromosome 6

Organism-specific databases

MGIiMGI:1916452 Ptms

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Initiator methionineiRemovedBy similarity
ChainiPRO_00001916332 – 101ParathymosinAdd BLAST100

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Modified residuei2N-acetylserineBy similarity1
Modified residuei2PhosphoserineBy similarity1
Modified residuei4N6-acetyllysineBy similarity1
Modified residuei5PhosphoserineCombined sources1
Modified residuei13PhosphoserineCombined sources1
Modified residuei15N6-acetyllysineCombined sources1
Modified residuei52PhosphothreonineBy similarity1
Modified residuei91N6-acetyllysineBy similarity1

Keywords - PTMi

Acetylation, Phosphoprotein

Proteomic databases

EPDiQ9D0J8
MaxQBiQ9D0J8
PaxDbiQ9D0J8
PeptideAtlasiQ9D0J8
PRIDEiQ9D0J8
TopDownProteomicsiQ9D0J8

PTM databases

iPTMnetiQ9D0J8
PhosphoSitePlusiQ9D0J8

Expressioni

Gene expression databases

BgeeiENSMUSG00000030122
CleanExiMM_PTMS
GenevisibleiQ9D0J8 MM

Interactioni

Protein-protein interaction databases

BioGridi213291, 1 interactor
IntActiQ9D0J8, 1 interactor
STRINGi10090.ENSMUSP00000032216

Structurei

3D structure databases

SMRiQ9D0J8
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Compositional biasi36 – 90Asp/Glu-rich (acidic)Add BLAST55

Sequence similaritiesi

Belongs to the pro/parathymosin family.Curated

Phylogenomic databases

eggNOGiENOG410J7IP Eukaryota
ENOG4111CKZ LUCA
GeneTreeiENSGT00910000144383
HOGENOMiHOG000115773
InParanoidiQ9D0J8
OMAiVEEPRSC

Family and domain databases

InterProiView protein in InterPro
IPR004931 Pro/parathymosin
PANTHERiPTHR22745 PTHR22745, 1 hit
PfamiView protein in Pfam
PF03247 Prothymosin, 1 hit

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

Q9D0J8-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSEKSVEAAA ELSAKDLKEK KDKVEEKAGR KERKKEVVEE EENGAEEEEE
60 70 80 90 100
ETAEDGEDDD EGDEEDEEEE EEDEGPVRKR TAEEEDEADP KRQKTENGAS

A
Length:101
Mass (Da):11,430
Last modified:January 23, 2007 - v3
Checksum:i5AF9F2A1541A67D5
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK011360 mRNA Translation: BAB27568.1
BC052699 mRNA Translation: AAH52699.1
CCDSiCCDS39630.1
RefSeqiNP_081264.1, NM_026988.2
UniGeneiMm.142187

Genome annotation databases

EnsembliENSMUST00000032216; ENSMUSP00000032216; ENSMUSG00000030122
GeneIDi69202
KEGGimmu:69202
UCSCiuc009dsm.2 mouse

Similar proteinsi

Entry informationi

Entry nameiPTMS_MOUSE
AccessioniPrimary (citable) accession number: Q9D0J8
Entry historyiIntegrated into UniProtKB/Swiss-Prot: February 15, 2005
Last sequence update: January 23, 2007
Last modified: February 28, 2018
This is version 98 of the entry and version 3 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. MGD cross-references
    Mouse Genome Database (MGD) cross-references in UniProtKB/Swiss-Prot
  2. SIMILARITY comments
    Index of protein domains and families

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