Znf524

Functionⁱ

May be involved in transcriptional regulation.

Regions

Feature key	Position(s)	DescriptionActions	Length
DNA bindingⁱ	49 – 59	A.T hookAdd BLAST	11
Zinc fingerⁱ	109 – 131	C2H2-type 1PROSITE-ProRule annotationAdd BLAST	23
Zinc fingerⁱ	137 – 159	C2H2-type 2PROSITE-ProRule annotationAdd BLAST	23
Zinc fingerⁱ	165 – 187	C2H2-type 3PROSITE-ProRule annotationAdd BLAST	23
Zinc fingerⁱ	193 – 216	C2H2-type 4PROSITE-ProRule annotationAdd BLAST	24

GO - Molecular functionⁱ

DNA binding Source: UniProtKB-KW
metal ion binding Source: UniProtKB-KW

View the complete GO annotation on QuickGO ...

Keywordsⁱ

Molecular function	DNA-binding
Biological process	Transcription, Transcription regulation
Ligand	Metal-binding, Zinc

Names & Taxonomyⁱ

Protein namesⁱ	Recommended name: Zinc finger protein 524
Gene namesⁱ	Name:Znf524 Synonyms:Zfp524
Organismⁱ	Mus musculus (Mouse)
Taxonomic identifierⁱ	10090 [NCBI]
Taxonomic lineageⁱ	cellular organisms › Eukaryota › Opisthokonta › Metazoa › Eumetazoa › Bilateria › Deuterostomia › Chordata › Craniata › Vertebrata › Gnathostomata › Teleostomi › Euteleostomi › Sarcopterygii › Dipnotetrapodomorpha › Tetrapoda › Amniota › Mammalia › Theria › Eutheria › Boreoeutheria › Euarchontoglires › Glires › Rodentia › Myomorpha › Muroidea › Muridae › Murinae › Mus › Mus
Proteomesⁱ	UP000000589 Componentⁱ: Chromosome 7

Organism-specific databases

MGIⁱ	MGI:1916740 Zfp524

Keywords - Cellular componentⁱ

Nucleus

PTM / Processingⁱ

Molecule processing

Feature key	Position(s)	DescriptionActions	Graphical view	Length
ChainⁱPRO_0000234580	1 – 321	Zinc finger protein 524Add BLAST		321

Proteomic databases

MaxQB - The MaxQuant DataBase More...MaxQBⁱ	Q9D0B1
PaxDbⁱ	Q9D0B1
PRIDEⁱ	Q9D0B1

PTM databases

PhosphoSitePlusⁱ	Q9D0B1

PhosphoSitePlusⁱ

Q9D0B1

Expressionⁱ

Gene expression databases

Bgeeⁱ	ENSMUSG00000051184 Expressed in 159 organ(s), highest expression level in kidney interstitium
CleanExⁱ	MM_ZFP524
Genevisibleⁱ	Q9D0B1 MM

Interactionⁱ

Protein-protein interaction databases

BioGridⁱ	211183, 1 interactor
STRINGⁱ	10090.ENSMUSP00000083533

Structureⁱ

3D structure databases

ProteinModelPortalⁱ	Q9D0B1
ModBaseⁱ	Search...
MobiDBⁱ	Search...

Family & Domainsⁱ

Sequence similaritiesⁱ

Belongs to the krueppel C2H2-type zinc-finger protein family.Curated

Zinc finger

Feature key	Position(s)	DescriptionActions	Length
Zinc fingerⁱ	109 – 131	C2H2-type 1PROSITE-ProRule annotationAdd BLAST	23
Zinc fingerⁱ	137 – 159	C2H2-type 2PROSITE-ProRule annotationAdd BLAST	23
Zinc fingerⁱ	165 – 187	C2H2-type 3PROSITE-ProRule annotationAdd BLAST	23
Zinc fingerⁱ	193 – 216	C2H2-type 4PROSITE-ProRule annotationAdd BLAST	24

Keywords - Domainⁱ

Repeat, Zinc-finger

Phylogenomic databases

eggNOGⁱ	KOG1721 Eukaryota COG5048 LUCA
Ensembl GeneTree More...GeneTreeⁱ	ENSGT00920000149029
HOGENOMⁱ	HOG000059663
HOVERGENⁱ	HBG079385
InParanoidⁱ	Q9D0B1
OMAⁱ	NTLRRHY
Database of Orthologous Groups More...OrthoDBⁱ	EOG091G0MXV
PhylomeDBⁱ	Q9D0B1
TreeFamⁱ	TF338348

Family and domain databases

InterProⁱ	View protein in InterPro IPR036236 Znf_C2H2_sf IPR013087 Znf_C2H2_type
Pfam protein domain database More...Pfamⁱ	View protein in Pfam PF00096 zf-C2H2, 2 hits
SMARTⁱ	View protein in SMART SM00355 ZnF_C2H2, 4 hits
SUPFAMⁱ	SSF57667 SSF57667, 2 hits
PROSITEⁱ	View protein in PROSITE PS00028 ZINC_FINGER_C2H2_1, 4 hits PS50157 ZINC_FINGER_C2H2_2, 4 hits

Sequenceⁱ

Sequence statusⁱ: Complete.

Q9D0B1-1 [UniParc]FASTA Add to basket

« Hide

        10         20         30         40         50
MDNPSSDPLP STLSGEEEKP LALLPPVPRG RRGRPPGGAT TSNRTLKSSL 
        60         70         80         90        100
PRKRGRPPRS EQETPLTAPV DSGGSSDLLL IDDQGVPYTV PEGSAADGPQ 
       110        120        130        140        150
GSGSKRAPHF CPVCLRAFPY LSDLERHSIS HSELKPHVCK DCGKTFKRSS 
       160        170        180        190        200
HLRRHCNIHA GLRPFRCVLC PRRFREAGEL AHHHRIHSGE RPYQCPSCRV 
       210        220        230        240        250
RFTEANTLRR HYKRKHPELV GMPVRLCPPN PRTQPLWDDD EGIPVQEGVQ 
       260        270        280        290        300
EESPEGKEPT WPISSTTSPL SGFTAGGSAG AGRGQEGQDT LVSGGIPTME 
       310        320 
GDQKQGPKPL GPGAIGHPPV D

Length:321

Mass (Da):34,809

Last modified:June 1, 2001 - v1

Checksum:ⁱ39F71B5061E40BAC

GO

Sequence cautionⁱ

The sequence BAB22215 differs from that shown. Reason: Frameshift at position 301.Curated

Experimental Info

Feature key	Position(s)	DescriptionActions	Graphical view	Length
Sequence conflictⁱ	255	E → G in BAB22215 (PubMed:16141072).Curated		1

Sequence databases

Select the link destinations: EMBLⁱ GenBankⁱ DDBJⁱ Links Updated	AK002594 mRNA Translation: BAB22215.1 Frameshift. AK011620 mRNA Translation: BAB27739.1 AK154328 mRNA Translation: BAE32517.1 BC019995 mRNA Translation: AAH19995.1
The Consensus CDS (CCDS) project More...CCDSⁱ	CCDS20752.1
NCBI Reference Sequences More...RefSeqⁱ	NP_079600.1, NM_025324.2 XP_006540339.1, XM_006540276.2 XP_006540340.1, XM_006540277.3 XP_011248972.1, XM_011250670.1
UniGeneⁱ	Mm.19974

Genome annotation databases

Ensemblⁱ	ENSMUST00000086349; ENSMUSP00000083533; ENSMUSG00000051184 ENSMUST00000207901; ENSMUSP00000146921; ENSMUSG00000051184 ENSMUST00000209030; ENSMUSP00000147095; ENSMUSG00000051184
GeneIDⁱ	66056
KEGGⁱ	mmu:66056
UCSC genome browser More...UCSCⁱ	uc009ezj.1 mouse

Similar proteinsⁱ

100% Identity
90% Identity
50% Identity

Protein	Similar proteins		Species	Score	Length	Source
Q9D0B1	Predicted gene 44973		MOUSE		189	UniRef100_Q9D0B1

Protein	Similar proteins		Species	Score	Length	Source
Q9D0B1	Predicted gene 44973		MOUSE		189	UniRef90_Q9D0B1
RCG22661		RAT		314
UPI000A306767		MUSPA		324
UPI000A31651D		MUSCR		321
UPI000B4EB7B5		MERUN		316

Protein	Similar proteins		Species	Score	Length	Source
Q9D0B1	Predicted gene 44973		MOUSE		189	UniRef50_Q9D0B1
RCG22661		RAT		314
Zinc finger protein 524		PTEAL		266
Uncharacterized protein		SARHA		272
Putative c2h2-type zn-finger protein		DESRO		263
+104

Cross-referencesⁱ

Sequence databases

Select the link destinations: EMBLⁱ GenBankⁱ DDBJⁱ Links Updated	AK002594 mRNA Translation: BAB22215.1 Frameshift. AK011620 mRNA Translation: BAB27739.1 AK154328 mRNA Translation: BAE32517.1 BC019995 mRNA Translation: AAH19995.1
CCDSⁱ	CCDS20752.1
RefSeqⁱ	NP_079600.1, NM_025324.2 XP_006540339.1, XM_006540276.2 XP_006540340.1, XM_006540277.3 XP_011248972.1, XM_011250670.1
UniGeneⁱ	Mm.19974

3D structure databases

ProteinModelPortalⁱ	Q9D0B1
ModBaseⁱ	Search...
MobiDBⁱ	Search...

Protein-protein interaction databases

BioGridⁱ	211183, 1 interactor
STRINGⁱ	10090.ENSMUSP00000083533

PTM databases

PhosphoSitePlusⁱ	Q9D0B1

PhosphoSitePlusⁱ

Q9D0B1

Proteomic databases

MaxQBⁱ	Q9D0B1
PaxDbⁱ	Q9D0B1
PRIDEⁱ	Q9D0B1

Protocols and materials databases

Structural Biology Knowledgebase	Search...

Structural Biology Knowledgebase

Search...

Genome annotation databases

Ensemblⁱ	ENSMUST00000086349; ENSMUSP00000083533; ENSMUSG00000051184 ENSMUST00000207901; ENSMUSP00000146921; ENSMUSG00000051184 ENSMUST00000209030; ENSMUSP00000147095; ENSMUSG00000051184
GeneIDⁱ	66056
KEGGⁱ	mmu:66056
UCSCⁱ	uc009ezj.1 mouse

Organism-specific databases

CTDⁱ	66056
MGIⁱ	MGI:1916740 Zfp524

Phylogenomic databases

eggNOGⁱ	KOG1721 Eukaryota COG5048 LUCA
GeneTreeⁱ	ENSGT00920000149029
HOGENOMⁱ	HOG000059663
HOVERGENⁱ	HBG079385
InParanoidⁱ	Q9D0B1
OMAⁱ	NTLRRHY
OrthoDBⁱ	EOG091G0MXV
PhylomeDBⁱ	Q9D0B1
TreeFamⁱ	TF338348

Miscellaneous databases

Protein Ontology More...PROⁱ	PR:Q9D0B1
SOURCEⁱ	Search...

Gene expression databases

Bgeeⁱ	ENSMUSG00000051184 Expressed in 159 organ(s), highest expression level in kidney interstitium
CleanExⁱ	MM_ZFP524
Genevisibleⁱ	Q9D0B1 MM

Family and domain databases

InterProⁱ	View protein in InterPro IPR036236 Znf_C2H2_sf IPR013087 Znf_C2H2_type
Pfamⁱ	View protein in Pfam PF00096 zf-C2H2, 2 hits
SMARTⁱ	View protein in SMART SM00355 ZnF_C2H2, 4 hits
SUPFAMⁱ	SSF57667 SSF57667, 2 hits
PROSITEⁱ	View protein in PROSITE PS00028 ZINC_FINGER_C2H2_1, 4 hits PS50157 ZINC_FINGER_C2H2_2, 4 hits
ProtoNetⁱ	Search...

Entry informationⁱ

Entry nameⁱ	ZN524_MOUSE
Accessionⁱ	Q9D0B1Primary (citable) accession number: Q9D0B1 Secondary accession number(s): Q9DCQ0
Entry historyⁱ	Integrated into UniProtKB/Swiss-Prot:	May 16, 2006
	Last sequence update:	June 1, 2001
	Last modified:	November 7, 2018
	This is version 144 of the entry and version 1 of the sequence. See complete history.
Entry statusⁱ	Reviewed (UniProtKB/Swiss-Prot)
Annotation program	Chordata Protein Annotation Program

Miscellaneousⁱ

Keywords - Technical termⁱ

Complete proteome, Reference proteome

Documents

SIMILARITY comments
Index of protein domains and families
MGD cross-references
Mouse Genome Database (MGD) cross-references in UniProtKB/Swiss-Prot

UniProtKB

UniParc

Help

UniRef

Proteomes

Annotation systems

Supporting data

UniProtKB - Q9D0B1 (ZN524_MOUSE)

Your basket is currently empty. i <p>When browsing through different UniProt proteins, you can use the ‘basket’ to save them, so that you can back to find or analyse them later.<p><a href='/help/basket' target='_top'>More...</a></p>

Zinc finger protein 524

Select a section on the left to see content.

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Regions

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

Organism-specific databases

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Nucleus

Nucleus

Keywords - Cellular componenti

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Proteomic databases

PTM databases

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

Protein-protein interaction databases

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

<p>This subsection of the ‘Family and domains’ section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Zinc finger

Keywords - Domaini

Phylogenomic databases

Family and domain databases

<p>This subsection of the ‘Sequence’ section reports difference(s) between the protein sequence shown in the UniProtKB entry and other available protein sequences derived from the same gene.<p><a href='/help/sequence_caution' target='_top'>More...</a></p>Sequence cautioni

Experimental Info

Sequence databases

Genome annotation databases

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

3D structure databases

Protein-protein interaction databases

PTM databases

Proteomic databases

Protocols and materials databases

Genome annotation databases

Organism-specific databases

Phylogenomic databases

Miscellaneous databases

Gene expression databases

Family and domain databases

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Documents

UniProt is an ELIXIR core data resource

Your basket is currently empty. ⁱ

Functionⁱ

GO - Molecular functionⁱ

Names & Taxonomyⁱ

Subcellular locationⁱ

Keywords - Cellular componentⁱ

PTM / Processingⁱ

Expressionⁱ

Interactionⁱ

Structureⁱ

Family & Domainsⁱ

Sequence similaritiesⁱ

Keywords - Domainⁱ

Sequence cautionⁱ

Cross-referencesⁱ

Entry informationⁱ

Miscellaneousⁱ

Keywords - Technical termⁱ