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Protein

Zinc finger protein 524

Gene

Znf524

Organism
Mus musculus (Mouse)
Status
Reviewed-Annotation score: -Experimental evidence at transcript leveli

Functioni

May be involved in transcriptional regulation.

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
DNA bindingi49 – 59A.T hookAdd BLAST11
Zinc fingeri109 – 131C2H2-type 1PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri137 – 159C2H2-type 2PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri165 – 187C2H2-type 3PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri193 – 216C2H2-type 4PROSITE-ProRule annotationAdd BLAST24

GO - Molecular functioni

Keywordsi

Molecular functionDNA-binding
Biological processTranscription, Transcription regulation
LigandMetal-binding, Zinc

Names & Taxonomyi

Protein namesi
Recommended name:
Zinc finger protein 524
Gene namesi
Name:Znf524
Synonyms:Zfp524
OrganismiMus musculus (Mouse)
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeMusMus
Proteomesi
  • UP000000589 Componenti: Chromosome 7

Organism-specific databases

MGIiMGI:1916740 Zfp524

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

Nucleus

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00002345801 – 321Zinc finger protein 524Add BLAST321

Proteomic databases

MaxQBiQ9D0B1
PaxDbiQ9D0B1
PRIDEiQ9D0B1

PTM databases

PhosphoSitePlusiQ9D0B1

Expressioni

Gene expression databases

BgeeiENSMUSG00000051184 Expressed in 159 organ(s), highest expression level in kidney interstitium
CleanExiMM_ZFP524
GenevisibleiQ9D0B1 MM

Interactioni

Protein-protein interaction databases

BioGridi211183, 1 interactor
STRINGi10090.ENSMUSP00000083533

Structurei

3D structure databases

ProteinModelPortaliQ9D0B1
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Zinc finger

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Zinc fingeri109 – 131C2H2-type 1PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri137 – 159C2H2-type 2PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri165 – 187C2H2-type 3PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri193 – 216C2H2-type 4PROSITE-ProRule annotationAdd BLAST24

Keywords - Domaini

Repeat, Zinc-finger

Phylogenomic databases

eggNOGiKOG1721 Eukaryota
COG5048 LUCA
GeneTreeiENSGT00920000149029
HOGENOMiHOG000059663
HOVERGENiHBG079385
InParanoidiQ9D0B1
OMAiNTLRRHY
OrthoDBiEOG091G0MXV
PhylomeDBiQ9D0B1
TreeFamiTF338348

Family and domain databases

InterProiView protein in InterPro
IPR036236 Znf_C2H2_sf
IPR013087 Znf_C2H2_type
PfamiView protein in Pfam
PF00096 zf-C2H2, 2 hits
SMARTiView protein in SMART
SM00355 ZnF_C2H2, 4 hits
SUPFAMiSSF57667 SSF57667, 2 hits
PROSITEiView protein in PROSITE
PS00028 ZINC_FINGER_C2H2_1, 4 hits
PS50157 ZINC_FINGER_C2H2_2, 4 hits

Sequencei

Sequence statusi: Complete.

Q9D0B1-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MDNPSSDPLP STLSGEEEKP LALLPPVPRG RRGRPPGGAT TSNRTLKSSL
60 70 80 90 100
PRKRGRPPRS EQETPLTAPV DSGGSSDLLL IDDQGVPYTV PEGSAADGPQ
110 120 130 140 150
GSGSKRAPHF CPVCLRAFPY LSDLERHSIS HSELKPHVCK DCGKTFKRSS
160 170 180 190 200
HLRRHCNIHA GLRPFRCVLC PRRFREAGEL AHHHRIHSGE RPYQCPSCRV
210 220 230 240 250
RFTEANTLRR HYKRKHPELV GMPVRLCPPN PRTQPLWDDD EGIPVQEGVQ
260 270 280 290 300
EESPEGKEPT WPISSTTSPL SGFTAGGSAG AGRGQEGQDT LVSGGIPTME
310 320
GDQKQGPKPL GPGAIGHPPV D
Length:321
Mass (Da):34,809
Last modified:June 1, 2001 - v1
Checksum:i39F71B5061E40BAC
GO

Sequence cautioni

The sequence BAB22215 differs from that shown. Reason: Frameshift at position 301.Curated

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Sequence conflicti255E → G in BAB22215 (PubMed:16141072).Curated1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK002594 mRNA Translation: BAB22215.1 Frameshift.
AK011620 mRNA Translation: BAB27739.1
AK154328 mRNA Translation: BAE32517.1
BC019995 mRNA Translation: AAH19995.1
CCDSiCCDS20752.1
RefSeqiNP_079600.1, NM_025324.2
XP_006540339.1, XM_006540276.2
XP_006540340.1, XM_006540277.3
XP_011248972.1, XM_011250670.1
UniGeneiMm.19974

Genome annotation databases

EnsembliENSMUST00000086349; ENSMUSP00000083533; ENSMUSG00000051184
ENSMUST00000207901; ENSMUSP00000146921; ENSMUSG00000051184
ENSMUST00000209030; ENSMUSP00000147095; ENSMUSG00000051184
GeneIDi66056
KEGGimmu:66056
UCSCiuc009ezj.1 mouse

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK002594 mRNA Translation: BAB22215.1 Frameshift.
AK011620 mRNA Translation: BAB27739.1
AK154328 mRNA Translation: BAE32517.1
BC019995 mRNA Translation: AAH19995.1
CCDSiCCDS20752.1
RefSeqiNP_079600.1, NM_025324.2
XP_006540339.1, XM_006540276.2
XP_006540340.1, XM_006540277.3
XP_011248972.1, XM_011250670.1
UniGeneiMm.19974

3D structure databases

ProteinModelPortaliQ9D0B1
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi211183, 1 interactor
STRINGi10090.ENSMUSP00000083533

PTM databases

PhosphoSitePlusiQ9D0B1

Proteomic databases

MaxQBiQ9D0B1
PaxDbiQ9D0B1
PRIDEiQ9D0B1

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSMUST00000086349; ENSMUSP00000083533; ENSMUSG00000051184
ENSMUST00000207901; ENSMUSP00000146921; ENSMUSG00000051184
ENSMUST00000209030; ENSMUSP00000147095; ENSMUSG00000051184
GeneIDi66056
KEGGimmu:66056
UCSCiuc009ezj.1 mouse

Organism-specific databases

CTDi66056
MGIiMGI:1916740 Zfp524

Phylogenomic databases

eggNOGiKOG1721 Eukaryota
COG5048 LUCA
GeneTreeiENSGT00920000149029
HOGENOMiHOG000059663
HOVERGENiHBG079385
InParanoidiQ9D0B1
OMAiNTLRRHY
OrthoDBiEOG091G0MXV
PhylomeDBiQ9D0B1
TreeFamiTF338348

Miscellaneous databases

PROiPR:Q9D0B1
SOURCEiSearch...

Gene expression databases

BgeeiENSMUSG00000051184 Expressed in 159 organ(s), highest expression level in kidney interstitium
CleanExiMM_ZFP524
GenevisibleiQ9D0B1 MM

Family and domain databases

InterProiView protein in InterPro
IPR036236 Znf_C2H2_sf
IPR013087 Znf_C2H2_type
PfamiView protein in Pfam
PF00096 zf-C2H2, 2 hits
SMARTiView protein in SMART
SM00355 ZnF_C2H2, 4 hits
SUPFAMiSSF57667 SSF57667, 2 hits
PROSITEiView protein in PROSITE
PS00028 ZINC_FINGER_C2H2_1, 4 hits
PS50157 ZINC_FINGER_C2H2_2, 4 hits
ProtoNetiSearch...

Entry informationi

Entry nameiZN524_MOUSE
AccessioniPrimary (citable) accession number: Q9D0B1
Secondary accession number(s): Q9DCQ0
Entry historyiIntegrated into UniProtKB/Swiss-Prot: May 16, 2006
Last sequence update: June 1, 2001
Last modified: November 7, 2018
This is version 144 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families
  2. MGD cross-references
    Mouse Genome Database (MGD) cross-references in UniProtKB/Swiss-Prot
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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