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Protein

STAGA complex 65 subunit gamma

Gene

Supt7l

Organism
Mus musculus (Mouse)
Status
Reviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

GO - Biological processi

Keywordsi

Biological processTranscription, Transcription regulation

Names & Taxonomyi

Protein namesi
Recommended name:
STAGA complex 65 subunit gamma
Alternative name(s):
SPTF-associated factor 65 gamma
Short name:
STAF65gamma
Suppressor of Ty 7-like
Gene namesi
Name:Supt7l
OrganismiMus musculus (Mouse)
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeMusMus
Proteomesi
  • UP000000589 Componenti: Chromosome 5

Organism-specific databases

MGIiMGI:1919445 Supt7l

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

Nucleus

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00000722341 – 412STAGA complex 65 subunit gammaAdd BLAST412

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Modified residuei106PhosphoserineBy similarity1
Cross-linki269Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2)By similarity
Modified residuei321PhosphoserineCombined sources1
Modified residuei332PhosphoserineCombined sources1

Post-translational modificationi

Sumoylated.By similarity

Keywords - PTMi

Isopeptide bond, Phosphoprotein, Ubl conjugation

Proteomic databases

EPDiQ9CZV5
MaxQBiQ9CZV5
PaxDbiQ9CZV5
PeptideAtlasiQ9CZV5
PRIDEiQ9CZV5

PTM databases

iPTMnetiQ9CZV5
PhosphoSitePlusiQ9CZV5

Expressioni

Gene expression databases

BgeeiENSMUSG00000053134 Expressed in 201 organ(s), highest expression level in olfactory epithelium
CleanExiMM_SUPT7L
ExpressionAtlasiQ9CZV5 baseline and differential
GenevisibleiQ9CZV5 MM

Interactioni

Subunit structurei

Component of the STAGA transcription coactivator-HAT complex, at least composed of SUPT3H, SUPT7L, GCN5L2, TAF5L, TAF6L, TADA3L, TAD1L, TAF10, TAF12 and TAF9.By similarity

GO - Molecular functioni

Protein-protein interaction databases

ComplexPortaliCPX-920 SAGA complex
STRINGi10090.ENSMUSP00000067337

Structurei

3D structure databases

ProteinModelPortaliQ9CZV5
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Phylogenomic databases

eggNOGiENOG410INFQ Eukaryota
ENOG410YK24 LUCA
GeneTreeiENSGT00390000005572
HOGENOMiHOG000072711
HOVERGENiHBG023396
InParanoidiQ9CZV5
KOiK11316
OMAiHAGFESA
OrthoDBiEOG091G0C0B
PhylomeDBiQ9CZV5
TreeFamiTF328615

Family and domain databases

Gene3Di1.10.20.10, 1 hit
InterProiView protein in InterPro
IPR006565 BTP
IPR009072 Histone-fold
IPR039460 SUPT7L
PANTHERiPTHR28598 PTHR28598, 1 hit
PfamiView protein in Pfam
PF07524 Bromo_TP, 1 hit
SMARTiView protein in SMART
SM00576 BTP, 1 hit

Sequence (1+)i

Sequence statusi: Complete.

This entry has 1 described isoform and 2 potential isoforms that are computationally mapped.Show allAlign All

Q9CZV5-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MLRYWGEIPI PSGQTNRSSF DLLPREFRLV EVHDPPLHQP SANKPKPPTM
60 70 80 90 100
LDIPSEPCSL TIHTIQLIQH NRRLRSLIAT AQTQSQQQTE GVKAEESEPL
110 120 130 140 150
PSCPGSPPLP DDLQPLDCKN PNAPFQIRHS DPESDFYRGK GEPVTELSWH
160 170 180 190 200
SCRQLLYQAV ATILAHTGFE CANESVLETL TDVAHEYCLK FTKLLRFAVD
210 220 230 240 250
REALLGQTPF PDVMEQVFHE VGIGSVLSLQ KFWQHRIKDY HTYMLQISKQ
260 270 280 290 300
LSEEYERIVN PEKATEDTKP VKIKEEPVSD ITFPVSEELE ADLASGDQSL
310 320 330 340 350
PIGVLGAQSE RFPSNLEVEA SPQAPSAEVN ASPLWNLAHV KMEPQESEEG
360 370 380 390 400
NVSAHGVLGS DVFEEPMSGM SEAGLPQSPD DSDSSYGSHS TDSLMGSSPV
410
FNQRCRKRMR KI
Length:412
Mass (Da):45,971
Last modified:June 1, 2001 - v1
Checksum:iB7BF1525BB44F6D5
GO

Computationally mapped potential isoform sequencesi

There are 2 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
E9PX66E9PX66_MOUSE
STAGA complex 65 subunit gamma
Supt7l
344Annotation score:
D3Z6Y8D3Z6Y8_MOUSE
STAGA complex 65 subunit gamma
Supt7l
363Annotation score:

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK012134 mRNA Translation: BAB28053.1
BC031447 mRNA Translation: AAH31447.1
CCDSiCCDS19186.1
RefSeqiNP_082426.1, NM_028150.2
UniGeneiMm.164187

Genome annotation databases

EnsembliENSMUST00000065388; ENSMUSP00000067337; ENSMUSG00000053134
ENSMUST00000201769; ENSMUSP00000144065; ENSMUSG00000053134
GeneIDi72195
KEGGimmu:72195
UCSCiuc008wyj.2 mouse

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK012134 mRNA Translation: BAB28053.1
BC031447 mRNA Translation: AAH31447.1
CCDSiCCDS19186.1
RefSeqiNP_082426.1, NM_028150.2
UniGeneiMm.164187

3D structure databases

ProteinModelPortaliQ9CZV5
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

ComplexPortaliCPX-920 SAGA complex
STRINGi10090.ENSMUSP00000067337

PTM databases

iPTMnetiQ9CZV5
PhosphoSitePlusiQ9CZV5

Proteomic databases

EPDiQ9CZV5
MaxQBiQ9CZV5
PaxDbiQ9CZV5
PeptideAtlasiQ9CZV5
PRIDEiQ9CZV5

Protocols and materials databases

DNASUi72195
Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSMUST00000065388; ENSMUSP00000067337; ENSMUSG00000053134
ENSMUST00000201769; ENSMUSP00000144065; ENSMUSG00000053134
GeneIDi72195
KEGGimmu:72195
UCSCiuc008wyj.2 mouse

Organism-specific databases

CTDi9913
MGIiMGI:1919445 Supt7l

Phylogenomic databases

eggNOGiENOG410INFQ Eukaryota
ENOG410YK24 LUCA
GeneTreeiENSGT00390000005572
HOGENOMiHOG000072711
HOVERGENiHBG023396
InParanoidiQ9CZV5
KOiK11316
OMAiHAGFESA
OrthoDBiEOG091G0C0B
PhylomeDBiQ9CZV5
TreeFamiTF328615

Miscellaneous databases

PROiPR:Q9CZV5
SOURCEiSearch...

Gene expression databases

BgeeiENSMUSG00000053134 Expressed in 201 organ(s), highest expression level in olfactory epithelium
CleanExiMM_SUPT7L
ExpressionAtlasiQ9CZV5 baseline and differential
GenevisibleiQ9CZV5 MM

Family and domain databases

Gene3Di1.10.20.10, 1 hit
InterProiView protein in InterPro
IPR006565 BTP
IPR009072 Histone-fold
IPR039460 SUPT7L
PANTHERiPTHR28598 PTHR28598, 1 hit
PfamiView protein in Pfam
PF07524 Bromo_TP, 1 hit
SMARTiView protein in SMART
SM00576 BTP, 1 hit
ProtoNetiSearch...

Entry informationi

Entry nameiST65G_MOUSE
AccessioniPrimary (citable) accession number: Q9CZV5
Entry historyiIntegrated into UniProtKB/Swiss-Prot: September 19, 2002
Last sequence update: June 1, 2001
Last modified: November 7, 2018
This is version 118 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. MGD cross-references
    Mouse Genome Database (MGD) cross-references in UniProtKB/Swiss-Prot
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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