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Protein

Probable U3 small nucleolar RNA-associated protein 11

Gene

Utp11

Organism
Mus musculus (Mouse)
Status
Reviewed-Annotation score: -Experimental evidence at transcript leveli

Functioni

Involved in nucleolar processing of pre-18S ribosomal RNA.By similarity

GO - Biological processi

Keywordsi

Biological processrRNA processing

Enzyme and pathway databases

ReactomeiR-MMU-6791226 Major pathway of rRNA processing in the nucleolus and cytosol

Names & Taxonomyi

Protein namesi
Recommended name:
Probable U3 small nucleolar RNA-associated protein 11
Short name:
U3 snoRNA-associated protein 11
Alternative name(s):
UTP11-like protein
Gene namesi
Name:Utp11
Synonyms:Utp11lImported
OrganismiMus musculus (Mouse)
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeMusMus
Proteomesi
  • UP000000589 Componenti: Chromosome 4

Organism-specific databases

MGIiMGI:1914455 Utp11

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

Nucleus

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00002110431 – 253Probable U3 small nucleolar RNA-associated protein 11Add BLAST253

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Cross-linki74Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2)By similarity
Cross-linki83Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2)By similarity
Cross-linki86Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2)By similarity
Modified residuei90PhosphothreonineBy similarity1
Cross-linki103Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2)By similarity
Cross-linki120Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2)By similarity
Cross-linki143Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2)By similarity
Cross-linki144Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2)By similarity
Cross-linki180Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2)By similarity
Cross-linki218Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2)By similarity
Cross-linki235Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2)By similarity
Cross-linki236Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2)By similarity
Modified residuei241PhosphoserineBy similarity1

Keywords - PTMi

Isopeptide bond, Phosphoprotein, Ubl conjugation

Proteomic databases

EPDiQ9CZJ1
MaxQBiQ9CZJ1
PaxDbiQ9CZJ1
PeptideAtlasiQ9CZJ1
PRIDEiQ9CZJ1

PTM databases

iPTMnetiQ9CZJ1
PhosphoSitePlusiQ9CZJ1

Expressioni

Gene expression databases

BgeeiENSMUSG00000028907 Expressed in 276 organ(s), highest expression level in embryo
GenevisibleiQ9CZJ1 MM

Interactioni

Subunit structurei

Component of the ribosomal small subunit (SSU) processome.By similarity

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000030738

Structurei

3D structure databases

ProteinModelPortaliQ9CZJ1
SMRiQ9CZJ1
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the UTP11 family.Curated

Phylogenomic databases

eggNOGiKOG3237 Eukaryota
COG5223 LUCA
GeneTreeiENSGT00390000005813
HOGENOMiHOG000231076
HOVERGENiHBG057139
InParanoidiQ9CZJ1
KOiK14769
OMAiERQKQYN
OrthoDBiEOG091G0H14
PhylomeDBiQ9CZJ1
TreeFamiTF314171

Family and domain databases

InterProiView protein in InterPro
IPR007144 SSU_processome_Utp11
PANTHERiPTHR12838 PTHR12838, 1 hit
PfamiView protein in Pfam
PF03998 Utp11, 1 hit
PIRSFiPIRSF015952 U3snoRNP11, 1 hit

Sequencei

Sequence statusi: Complete.

Q9CZJ1-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MSAAFRKAAK TRQREHRERS QPGFRKRLGL LEKKKDYKLR ANDYHKKQDF
60 70 80 90 100
LRALRKKALE KNPDEFYYKM TRAKLQDGVH IFKENKEEVT AEQLKLMRTQ
110 120 130 140 150
DIKYIEMKRV AEAKKIERLK SELHLLDFQG KQQKKHVFFF DTKKEVERFD
160 170 180 190 200
VATHLQTAPE LVDRVYNRPR IETLQKERVK GATPQTGLKR IAKERQKQYD
210 220 230 240 250
CLTQRIEREK QLFVVAQKIQ TRKDLMDKTQ KVKVKKETVN SPAIYRFQTR

RKR
Length:253
Mass (Da):30,551
Last modified:June 1, 2001 - v1
Checksum:i469CD89D485BAF9F
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK008801 mRNA Translation: BAB25903.1
AK012550 mRNA Translation: BAB28310.1
AK145266 mRNA Translation: BAE26334.1
AK147113 mRNA Translation: BAE27685.1
BC061074 mRNA Translation: AAH61074.1
CCDSiCCDS18623.1
RefSeqiNP_080307.1, NM_026031.3
UniGeneiMm.259121

Genome annotation databases

EnsembliENSMUST00000030738; ENSMUSP00000030738; ENSMUSG00000028907
GeneIDi67205
KEGGimmu:67205
UCSCiuc008uqu.1 mouse

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK008801 mRNA Translation: BAB25903.1
AK012550 mRNA Translation: BAB28310.1
AK145266 mRNA Translation: BAE26334.1
AK147113 mRNA Translation: BAE27685.1
BC061074 mRNA Translation: AAH61074.1
CCDSiCCDS18623.1
RefSeqiNP_080307.1, NM_026031.3
UniGeneiMm.259121

3D structure databases

ProteinModelPortaliQ9CZJ1
SMRiQ9CZJ1
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000030738

PTM databases

iPTMnetiQ9CZJ1
PhosphoSitePlusiQ9CZJ1

Proteomic databases

EPDiQ9CZJ1
MaxQBiQ9CZJ1
PaxDbiQ9CZJ1
PeptideAtlasiQ9CZJ1
PRIDEiQ9CZJ1

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSMUST00000030738; ENSMUSP00000030738; ENSMUSG00000028907
GeneIDi67205
KEGGimmu:67205
UCSCiuc008uqu.1 mouse

Organism-specific databases

CTDi51118
MGIiMGI:1914455 Utp11

Phylogenomic databases

eggNOGiKOG3237 Eukaryota
COG5223 LUCA
GeneTreeiENSGT00390000005813
HOGENOMiHOG000231076
HOVERGENiHBG057139
InParanoidiQ9CZJ1
KOiK14769
OMAiERQKQYN
OrthoDBiEOG091G0H14
PhylomeDBiQ9CZJ1
TreeFamiTF314171

Enzyme and pathway databases

ReactomeiR-MMU-6791226 Major pathway of rRNA processing in the nucleolus and cytosol

Miscellaneous databases

PROiPR:Q9CZJ1
SOURCEiSearch...

Gene expression databases

BgeeiENSMUSG00000028907 Expressed in 276 organ(s), highest expression level in embryo
GenevisibleiQ9CZJ1 MM

Family and domain databases

InterProiView protein in InterPro
IPR007144 SSU_processome_Utp11
PANTHERiPTHR12838 PTHR12838, 1 hit
PfamiView protein in Pfam
PF03998 Utp11, 1 hit
PIRSFiPIRSF015952 U3snoRNP11, 1 hit
ProtoNetiSearch...

Entry informationi

Entry nameiUTP11_MOUSE
AccessioniPrimary (citable) accession number: Q9CZJ1
Secondary accession number(s): Q3UI21, Q9CVB5
Entry historyiIntegrated into UniProtKB/Swiss-Prot: April 4, 2003
Last sequence update: June 1, 2001
Last modified: September 12, 2018
This is version 111 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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