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Protein

THUMP domain-containing protein 2

Gene

Thumpd2

Organism
Mus musculus (Mouse)
Status
Reviewed-Annotation score: -Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionMethyltransferase, RNA-binding, Transferase

Names & Taxonomyi

Protein namesi
Recommended name:
THUMP domain-containing protein 2
Gene namesi
Name:Thumpd2
OrganismiMus musculus (Mouse)
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeMusMus
Proteomesi
  • UP000000589 Componenti: Chromosome 17

Organism-specific databases

MGIiMGI:1919417 Thumpd2

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00000725331 – 528THUMP domain-containing protein 2Add BLAST528

Proteomic databases

EPDiQ9CZB3
MaxQBiQ9CZB3
PaxDbiQ9CZB3
PeptideAtlasiQ9CZB3
PRIDEiQ9CZB3

PTM databases

iPTMnetiQ9CZB3
PhosphoSitePlusiQ9CZB3

Expressioni

Gene expression databases

BgeeiENSMUSG00000024246
CleanExiMM_THUMPD2
GenevisibleiQ9CZB3 MM

Interactioni

Protein-protein interaction databases

IntActiQ9CZB3, 2 interactors
MINTiQ9CZB3
STRINGi10090.ENSMUSP00000025093

Structurei

3D structure databases

ProteinModelPortaliQ9CZB3
SMRiQ9CZB3
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini162 – 266THUMPPROSITE-ProRule annotationAdd BLAST105

Sequence similaritiesi

Belongs to the methyltransferase superfamily.Curated

Phylogenomic databases

eggNOGiENOG410KCNV Eukaryota
COG1041 LUCA
GeneTreeiENSGT00530000063557
HOGENOMiHOG000013141
HOVERGENiHBG061192
InParanoidiQ9CZB3
OMAiWKADLRN
OrthoDBiEOG091G1D46
TreeFamiTF313093

Family and domain databases

InterProiView protein in InterPro
IPR000241 RNA_methylase_dom
IPR029063 SAM-dependent_MTases
IPR004114 THUMP_dom
PfamiView protein in Pfam
PF02926 THUMP, 1 hit
PF01170 UPF0020, 1 hit
SMARTiView protein in SMART
SM00981 THUMP, 1 hit
SUPFAMiSSF53335 SSF53335, 1 hit
PROSITEiView protein in PROSITE
PS51165 THUMP, 1 hit

Sequencei

Sequence statusi: Complete.

Q9CZB3-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MAVAQADPGS DPAGGARFFC TAGRGLEPFL MREVRARLEA TQVEYISGKV
60 70 80 90 100
FFTTCSDLPS MKKLKSAERL FVLIKKQLPI AVSSLHKGKI LNEMQRFVND
110 120 130 140 150
DPGSWLEAIS LWKKLLEHDP KREKVSQRDA NPLKRKAGEN ETIIAKKLKV
160 170 180 190 200
EEKQEVAKDH GESQEDKLLQ GSPEQGEAVT RTELQDHRLN STTEKAADAQ
210 220 230 240 250
DQEDLTFRVS CRCTGNVRKV ITGQEAGRVI GLALMRQFGW KADLRNPNIE
260 270 280 290 300
IFMHLSDAYS VVGIPLLRMP LASRTYIQTA GLRSTIAWAM ASIAEIKAGA
310 320 330 340 350
LVLDPMCGLG TILVEAAEEW PDVFYMGADM SDAQLLGACD NLKAAGLTDR
360 370 380 390 400
IELLKSSVTD LPLPSQSTDV IISDIPFGKK FKLGKDIKSI LQEMERVLRV
410 420 430 440 450
GGAMVLLLSE DHHRHLTDCG GSSIPLTSKG HIAEPEMKTL SNPDRTGAPD
460 470 480 490 500
TASPSQRASS VQCLGRMRPC GSLVPVESFK VSLGKTDAFI CKYKKAQASG
510 520
LSSAECHEPG AHTEMAAMQE SPSLQDSL
Length:528
Mass (Da):57,669
Last modified:July 27, 2011 - v3
Checksum:i6242BC0BC3976CC5
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK012806 mRNA Translation: BAB28484.1
AC165966 Genomic DNA No translation available.
CCDSiCCDS50190.1
RefSeqiNP_082414.1, NM_028138.1
UniGeneiMm.273257

Genome annotation databases

EnsembliENSMUST00000025093; ENSMUSP00000025093; ENSMUSG00000024246
GeneIDi72167
KEGGimmu:72167
UCSCiuc008drp.2 mouse

Similar proteinsi

Entry informationi

Entry nameiTHUM2_MOUSE
AccessioniPrimary (citable) accession number: Q9CZB3
Entry historyiIntegrated into UniProtKB/Swiss-Prot: July 5, 2004
Last sequence update: July 27, 2011
Last modified: April 25, 2018
This is version 101 of the entry and version 3 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. MGD cross-references
    Mouse Genome Database (MGD) cross-references in UniProtKB/Swiss-Prot
  2. SIMILARITY comments
    Index of protein domains and families

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