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Protein

28S ribosomal protein S22, mitochondrial

Gene

Mrps22

Organism
Mus musculus (Mouse)
Status
Reviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

Keywordsi

Molecular functionRibonucleoprotein, Ribosomal protein

Enzyme and pathway databases

ReactomeiR-MMU-5389840 Mitochondrial translation elongation
R-MMU-5419276 Mitochondrial translation termination

Names & Taxonomyi

Protein namesi
Recommended name:
28S ribosomal protein S22, mitochondrial
Short name:
MRP-S22
Short name:
S22mt
Gene namesi
Name:Mrps22
Synonyms:Rpms22
OrganismiMus musculus (Mouse)
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeMusMus
Proteomesi
  • UP000000589 Componenti: Chromosome 9

Organism-specific databases

MGIiMGI:1928137 Mrps22

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

Mitochondrion

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00000877041 – 35928S ribosomal protein S22, mitochondrialAdd BLAST359

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Modified residuei54PhosphoserineBy similarity1
Modified residuei210N6-acetyllysineBy similarity1

Keywords - PTMi

Acetylation, Phosphoprotein

Proteomic databases

EPDiQ9CXW2
MaxQBiQ9CXW2
PaxDbiQ9CXW2
PeptideAtlasiQ9CXW2
PRIDEiQ9CXW2

PTM databases

iPTMnetiQ9CXW2
PhosphoSitePlusiQ9CXW2

Expressioni

Gene expression databases

BgeeiENSMUSG00000032459 Expressed in 287 organ(s), highest expression level in primary oocyte
CleanExiMM_MRPS22
GenevisibleiQ9CXW2 MM

Interactioni

Subunit structurei

Component of the mitochondrial ribosome small subunit (28S) which comprises a 12S rRNA and about 30 distinct proteins.By similarity

Protein-protein interaction databases

BioGridi211091, 2 interactors
IntActiQ9CXW2, 2 interactors
MINTiQ9CXW2
STRINGi10090.ENSMUSP00000035034

Structurei

3D structure databases

ProteinModelPortaliQ9CXW2
SMRiQ9CXW2
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Phylogenomic databases

eggNOGiKOG3890 Eukaryota
ENOG4111I44 LUCA
GeneTreeiENSGT00390000006095
HOGENOMiHOG000154215
HOVERGENiHBG017759
InParanoidiQ9CXW2
KOiK17401
OMAiMAFFYAW
OrthoDBiEOG091G0H6J
PhylomeDBiQ9CXW2
TreeFamiTF312882

Family and domain databases

InterProiView protein in InterPro
IPR019374 Ribosomal_S22_mit
PANTHERiPTHR13071 PTHR13071, 1 hit
PfamiView protein in Pfam
PF10245 MRP-S22, 1 hit

Sequencei

Sequence statusi: Complete.

Q9CXW2-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MAAVRTPLSL WRFQLGSRRA RRVCTRATAQ RHPDALLATR PQPFEVGQPR
60 70 80 90 100
RLLSSEAESG SSEVKKPAFM DEEVQRILTK ITGLDLQKTF RPAIQPLKPP
110 120 130 140 150
TYKLMTQAQL EEATRLAVEA AKVRLKMPPV LEERKPINDV LAEDKILEGT
160 170 180 190 200
ETNKYVFTDI SYNIPHRERF IVVREPSGTL RKASWEERDR VIQIYFPKEG
210 220 230 240 250
RRVLPPVIFK DENLKTMYSQ DRHADVLNLC VAQFEPDSAE YIKVHHQTYE
260 270 280 290 300
DIDRHGKYEL LRSTRHFGGM AWYFVNKKKI DGLLIDQIQR DLVDDATSLV
310 320 330 340 350
QLYHMLHPDG QSAQEAKEQA AEGVDLIKVF AKTEAQRGAY IELALQTYQE

IVTSHSAAS
Length:359
Mass (Da):41,192
Last modified:April 27, 2001 - v1
Checksum:iC258AD152738F1C7
GO

Sequence cautioni

The sequence AAH21882 differs from that shown. Reason: Erroneous initiation.Curated

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK003836 mRNA Translation: BAB23027.2
AK013925 mRNA Translation: BAB29061.1
AK154600 mRNA Translation: BAE32703.1
BC021882 mRNA Translation: AAH21882.1 Different initiation.
BC051198 mRNA Translation: AAH51198.1
CCDSiCCDS23427.1
RefSeqiNP_079761.1, NM_025485.3
UniGeneiMm.17949

Genome annotation databases

EnsembliENSMUST00000035034; ENSMUSP00000035034; ENSMUSG00000032459
GeneIDi64655
KEGGimmu:64655
UCSCiuc009rdn.3 mouse

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK003836 mRNA Translation: BAB23027.2
AK013925 mRNA Translation: BAB29061.1
AK154600 mRNA Translation: BAE32703.1
BC021882 mRNA Translation: AAH21882.1 Different initiation.
BC051198 mRNA Translation: AAH51198.1
CCDSiCCDS23427.1
RefSeqiNP_079761.1, NM_025485.3
UniGeneiMm.17949

3D structure databases

ProteinModelPortaliQ9CXW2
SMRiQ9CXW2
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi211091, 2 interactors
IntActiQ9CXW2, 2 interactors
MINTiQ9CXW2
STRINGi10090.ENSMUSP00000035034

PTM databases

iPTMnetiQ9CXW2
PhosphoSitePlusiQ9CXW2

Proteomic databases

EPDiQ9CXW2
MaxQBiQ9CXW2
PaxDbiQ9CXW2
PeptideAtlasiQ9CXW2
PRIDEiQ9CXW2

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSMUST00000035034; ENSMUSP00000035034; ENSMUSG00000032459
GeneIDi64655
KEGGimmu:64655
UCSCiuc009rdn.3 mouse

Organism-specific databases

CTDi56945
MGIiMGI:1928137 Mrps22

Phylogenomic databases

eggNOGiKOG3890 Eukaryota
ENOG4111I44 LUCA
GeneTreeiENSGT00390000006095
HOGENOMiHOG000154215
HOVERGENiHBG017759
InParanoidiQ9CXW2
KOiK17401
OMAiMAFFYAW
OrthoDBiEOG091G0H6J
PhylomeDBiQ9CXW2
TreeFamiTF312882

Enzyme and pathway databases

ReactomeiR-MMU-5389840 Mitochondrial translation elongation
R-MMU-5419276 Mitochondrial translation termination

Miscellaneous databases

PROiPR:Q9CXW2
SOURCEiSearch...

Gene expression databases

BgeeiENSMUSG00000032459 Expressed in 287 organ(s), highest expression level in primary oocyte
CleanExiMM_MRPS22
GenevisibleiQ9CXW2 MM

Family and domain databases

InterProiView protein in InterPro
IPR019374 Ribosomal_S22_mit
PANTHERiPTHR13071 PTHR13071, 1 hit
PfamiView protein in Pfam
PF10245 MRP-S22, 1 hit
ProtoNetiSearch...

Entry informationi

Entry nameiRT22_MOUSE
AccessioniPrimary (citable) accession number: Q9CXW2
Secondary accession number(s): Q3U3T2, Q8VDG9, Q9D185
Entry historyiIntegrated into UniProtKB/Swiss-Prot: April 27, 2001
Last sequence update: April 27, 2001
Last modified: September 12, 2018
This is version 111 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families
  2. Ribosomal proteins
    Ribosomal proteins families and list of entries
  3. MGD cross-references
    Mouse Genome Database (MGD) cross-references in UniProtKB/Swiss-Prot
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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