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Protein

Eukaryotic translation initiation factor 1b

Gene

Eif1b

Organism
Mus musculus (Mouse)
Status
Reviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

Probably involved in translation.

GO - Molecular functioni

  • ribosomal small subunit binding Source: GO_Central
  • RNA binding Source: GO_Central
  • translation initiation factor activity Source: GO_Central

Keywordsi

Molecular functionInitiation factor
Biological processProtein biosynthesis

Names & Taxonomyi

Protein namesi
Recommended name:
Eukaryotic translation initiation factor 1b
Short name:
eIF1b
Gene namesi
Name:Eif1b
OrganismiMus musculus (Mouse)
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeMusMus
Proteomesi
  • UP000000589 Componenti: Chromosome 9

Organism-specific databases

MGIiMGI:1916219 Eif1b

Subcellular locationi

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Initiator methionineiRemovedBy similarity
ChainiPRO_00001305592 – 113Eukaryotic translation initiation factor 1bAdd BLAST112

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Modified residuei2N-acetylserineBy similarity1
Modified residuei9PhosphoserineBy similarity1

Keywords - PTMi

Acetylation, Phosphoprotein

Proteomic databases

EPDiQ9CXU9
MaxQBiQ9CXU9
PaxDbiQ9CXU9
PeptideAtlasiQ9CXU9
PRIDEiQ9CXU9

PTM databases

iPTMnetiQ9CXU9
PhosphoSitePlusiQ9CXU9

Expressioni

Gene expression databases

BgeeiENSMUSG00000006941 Expressed in 291 organ(s), highest expression level in cerebral cortex
CleanExiMM_EIF1B
ExpressionAtlasiQ9CXU9 baseline and differential
GenevisibleiQ9CXU9 MM

Interactioni

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000007139

Structurei

3D structure databases

ProteinModelPortaliQ9CXU9
SMRiQ9CXU9
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the SUI1 family.Curated

Phylogenomic databases

eggNOGiKOG1770 Eukaryota
COG0023 LUCA
GeneTreeiENSGT00390000015789
HOGENOMiHOG000279813
HOVERGENiHBG000295
InParanoidiQ9CXU9
KOiK03113
OMAiMSAIQNF
OrthoDBiEOG091G10OC
PhylomeDBiQ9CXU9
TreeFamiTF314417

Family and domain databases

CDDicd11566 eIF1_SUI1, 1 hit
InterProiView protein in InterPro
IPR001950 SUI1
IPR036877 SUI1_dom_sf
IPR005874 SUI1_euk
PfamiView protein in Pfam
PF01253 SUI1, 1 hit
PIRSFiPIRSF004499 SUI1_euk, 1 hit
SUPFAMiSSF55159 SSF55159, 1 hit
TIGRFAMsiTIGR01160 SUI1_MOF2, 1 hit
PROSITEiView protein in PROSITE
PS50296 SUI1, 1 hit

Sequence (1+)i

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

This entry has 1 described isoform and 1 potential isoform that is computationally mapped.Show allAlign All

Q9CXU9-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MSTIQNLQSF DPFADATKGD DLLPAGTEDY IHIRIQQRNG RKTLTTVQGI
60 70 80 90 100
ADDYDKKKLV KAFKKKFACN GTVIEHPEYG EVIQLQGDQR KNICQFLLEV
110
GIVKEEQLKV HGF
Length:113
Mass (Da):12,824
Last modified:May 10, 2004 - v2
Checksum:i4522A8B692654FE1
GO

Computationally mapped potential isoform sequencesi

There is 1 potential isoform mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
A0A1L1SSA3A0A1L1SSA3_MOUSE
Eukaryotic translation initiation f...
Eif1b
100Annotation score:

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Sequence conflicti21D → G in BAB29089 (PubMed:16141072).Curated1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK005192 mRNA Translation: BAB23874.1
AK013965 mRNA Translation: BAB29089.1
BC030319 mRNA Translation: AAH30319.1
BC033505 mRNA Translation: AAH33505.1
CCDSiCCDS23628.1
RefSeqiNP_081168.1, NM_026892.3
UniGeneiMm.28753

Genome annotation databases

EnsembliENSMUST00000007139; ENSMUSP00000007139; ENSMUSG00000006941
GeneIDi68969
KEGGimmu:68969
UCSCiuc009scp.2 mouse

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK005192 mRNA Translation: BAB23874.1
AK013965 mRNA Translation: BAB29089.1
BC030319 mRNA Translation: AAH30319.1
BC033505 mRNA Translation: AAH33505.1
CCDSiCCDS23628.1
RefSeqiNP_081168.1, NM_026892.3
UniGeneiMm.28753

3D structure databases

ProteinModelPortaliQ9CXU9
SMRiQ9CXU9
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000007139

PTM databases

iPTMnetiQ9CXU9
PhosphoSitePlusiQ9CXU9

Proteomic databases

EPDiQ9CXU9
MaxQBiQ9CXU9
PaxDbiQ9CXU9
PeptideAtlasiQ9CXU9
PRIDEiQ9CXU9

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSMUST00000007139; ENSMUSP00000007139; ENSMUSG00000006941
GeneIDi68969
KEGGimmu:68969
UCSCiuc009scp.2 mouse

Organism-specific databases

CTDi10289
MGIiMGI:1916219 Eif1b

Phylogenomic databases

eggNOGiKOG1770 Eukaryota
COG0023 LUCA
GeneTreeiENSGT00390000015789
HOGENOMiHOG000279813
HOVERGENiHBG000295
InParanoidiQ9CXU9
KOiK03113
OMAiMSAIQNF
OrthoDBiEOG091G10OC
PhylomeDBiQ9CXU9
TreeFamiTF314417

Miscellaneous databases

ChiTaRSiEif1b mouse
PROiPR:Q9CXU9
SOURCEiSearch...

Gene expression databases

BgeeiENSMUSG00000006941 Expressed in 291 organ(s), highest expression level in cerebral cortex
CleanExiMM_EIF1B
ExpressionAtlasiQ9CXU9 baseline and differential
GenevisibleiQ9CXU9 MM

Family and domain databases

CDDicd11566 eIF1_SUI1, 1 hit
InterProiView protein in InterPro
IPR001950 SUI1
IPR036877 SUI1_dom_sf
IPR005874 SUI1_euk
PfamiView protein in Pfam
PF01253 SUI1, 1 hit
PIRSFiPIRSF004499 SUI1_euk, 1 hit
SUPFAMiSSF55159 SSF55159, 1 hit
TIGRFAMsiTIGR01160 SUI1_MOF2, 1 hit
PROSITEiView protein in PROSITE
PS50296 SUI1, 1 hit
ProtoNetiSearch...

Entry informationi

Entry nameiEIF1B_MOUSE
AccessioniPrimary (citable) accession number: Q9CXU9
Entry historyiIntegrated into UniProtKB/Swiss-Prot: May 10, 2004
Last sequence update: May 10, 2004
Last modified: November 7, 2018
This is version 112 of the entry and version 2 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families
  2. Translation initiation factors
    List of translation initiation factor entries
  3. MGD cross-references
    Mouse Genome Database (MGD) cross-references in UniProtKB/Swiss-Prot
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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