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Protein

KATNB1-like protein 1

Gene

Katnbl1

Organism
Mus musculus (Mouse)
Status
Reviewed-Annotation score: -Experimental evidence at transcript leveli

Functioni

Regulates microtubule-severing activity of KATNAL1 in a concentration-dependent manner in vitro.By similarity

GO - Biological processi

Names & Taxonomyi

Protein namesi
Recommended name:
KATNB1-like protein 1
Alternative name(s):
Katanin p80 subunit B-like 1
Gene namesi
Name:Katnbl1
OrganismiMus musculus (Mouse)
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeMusMus
Proteomesi
  • UP000000589 Componenti: Chromosome 2

Organism-specific databases

MGIiMGI:1919675 Katnbl1

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

Cytoplasm, Cytoskeleton, Nucleus

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00000899821 – 299KATNB1-like protein 1Add BLAST299

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Modified residuei56PhosphoserineBy similarity1

Keywords - PTMi

Phosphoprotein

Proteomic databases

EPDiQ9CWJ3
MaxQBiQ9CWJ3
PaxDbiQ9CWJ3
PeptideAtlasiQ9CWJ3
PRIDEiQ9CWJ3

PTM databases

iPTMnetiQ9CWJ3
PhosphoSitePlusiQ9CWJ3

Expressioni

Gene expression databases

BgeeiENSMUSG00000027132 Expressed in 243 organ(s), highest expression level in skin of back
GenevisibleiQ9CWJ3 MM

Interactioni

Subunit structurei

Interacts with KATNA1 and KATNAL1; these interactions are competed by KATNB1 which has a higher affinity for them.By similarity

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000028552

Structurei

3D structure databases

ProteinModelPortaliQ9CWJ3
SMRiQ9CWJ3
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Motif

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Motifi8 – 15Nuclear localization signalPROSITE-ProRule annotation8

Phylogenomic databases

eggNOGiENOG410IIPM Eukaryota
ENOG4111ZSI LUCA
GeneTreeiENSGT00390000012351
HOGENOMiHOG000231426
HOVERGENiHBG055310
InParanoidiQ9CWJ3
OMAiMASEAHN
OrthoDBiEOG091G14WC
PhylomeDBiQ9CWJ3
TreeFamiTF332359

Family and domain databases

InterProiView protein in InterPro
IPR028021 Katanin_C-terminal
PfamiView protein in Pfam
PF13925 Katanin_con80, 1 hit

Sequencei

Sequence statusi: Complete.

Q9CWJ3-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MAFDTHHVKK RNFSNSIDLP RKRISNFTSK NMKEVKRSPK QLAAYISRTV
60 70 80 90 100
AQAVKSPEKL RKVLYHRKLV RRSFPNPCYK TKQSPKSGGC DMANKENELA
110 120 130 140 150
CAGHLPENLR HDSRTFVINT SDSGSSQTES PSSKYSGFFS EVSQDHETMA
160 170 180 190 200
QVLFSRNLRL NVALTFWRKR SISELVAYLV RIEDLGVVVD CLPVLTNSLQ
210 220 230 240 250
EEKQYISLGC CVDLLPLVKS LLQSRFEEYV IVGLNWLQAV IKRWWSELSS
260 270 280 290
TSEIISDGNI KILKQQLSGL WEQESHLTLV PGYTGNIAKD VDAYLLQLH
Length:299
Mass (Da):34,035
Last modified:June 1, 2001 - v1
Checksum:i9799B6ABB99FF6EE
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK010654 mRNA Translation: BAB27094.1
AK036861 mRNA Translation: BAC29607.1
AK151464 mRNA Translation: BAE30422.1
AK152570 mRNA Translation: BAE31322.1
AK168639 mRNA Translation: BAE40498.1
BC003216 mRNA Translation: AAH03216.1
BC080661 mRNA Translation: AAH80661.1
BC012402 mRNA Translation: AAH12402.1
CCDSiCCDS16554.1
RefSeqiNP_077216.1, NM_024254.3
UniGeneiMm.425091

Genome annotation databases

EnsembliENSMUST00000028552; ENSMUSP00000028552; ENSMUSG00000027132
GeneIDi72425
KEGGimmu:72425
UCSCiuc008lpa.1 mouse

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK010654 mRNA Translation: BAB27094.1
AK036861 mRNA Translation: BAC29607.1
AK151464 mRNA Translation: BAE30422.1
AK152570 mRNA Translation: BAE31322.1
AK168639 mRNA Translation: BAE40498.1
BC003216 mRNA Translation: AAH03216.1
BC080661 mRNA Translation: AAH80661.1
BC012402 mRNA Translation: AAH12402.1
CCDSiCCDS16554.1
RefSeqiNP_077216.1, NM_024254.3
UniGeneiMm.425091

3D structure databases

ProteinModelPortaliQ9CWJ3
SMRiQ9CWJ3
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000028552

PTM databases

iPTMnetiQ9CWJ3
PhosphoSitePlusiQ9CWJ3

Proteomic databases

EPDiQ9CWJ3
MaxQBiQ9CWJ3
PaxDbiQ9CWJ3
PeptideAtlasiQ9CWJ3
PRIDEiQ9CWJ3

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSMUST00000028552; ENSMUSP00000028552; ENSMUSG00000027132
GeneIDi72425
KEGGimmu:72425
UCSCiuc008lpa.1 mouse

Organism-specific databases

CTDi79768
MGIiMGI:1919675 Katnbl1

Phylogenomic databases

eggNOGiENOG410IIPM Eukaryota
ENOG4111ZSI LUCA
GeneTreeiENSGT00390000012351
HOGENOMiHOG000231426
HOVERGENiHBG055310
InParanoidiQ9CWJ3
OMAiMASEAHN
OrthoDBiEOG091G14WC
PhylomeDBiQ9CWJ3
TreeFamiTF332359

Miscellaneous databases

PROiPR:Q9CWJ3
SOURCEiSearch...

Gene expression databases

BgeeiENSMUSG00000027132 Expressed in 243 organ(s), highest expression level in skin of back
GenevisibleiQ9CWJ3 MM

Family and domain databases

InterProiView protein in InterPro
IPR028021 Katanin_C-terminal
PfamiView protein in Pfam
PF13925 Katanin_con80, 1 hit
ProtoNetiSearch...

Entry informationi

Entry nameiKTBL1_MOUSE
AccessioniPrimary (citable) accession number: Q9CWJ3
Secondary accession number(s): Q3U7P7, Q8C7R6
Entry historyiIntegrated into UniProtKB/Swiss-Prot: August 30, 2005
Last sequence update: June 1, 2001
Last modified: September 12, 2018
This is version 101 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. MGD cross-references
    Mouse Genome Database (MGD) cross-references in UniProtKB/Swiss-Prot
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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