Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein

Golgin subfamily A member 1

Gene

Golga1

Organism
Mus musculus (Mouse)
Status
Reviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

Involved in vesicular trafficking at the Golgi apparatus level. Involved in endosome-to-Golgi trafficking.By similarity

Enzyme and pathway databases

ReactomeiR-MMU-6811440 Retrograde transport at the Trans-Golgi-Network

Names & Taxonomyi

Protein namesi
Recommended name:
Golgin subfamily A member 1
Alternative name(s):
Golgin-97
Gene namesi
Name:Golga1
OrganismiMus musculus (Mouse)
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeMusMus
Proteomesi
  • UP000000589 Componenti: Chromosome 2

Organism-specific databases

MGIiMGI:1924149 Golga1

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

Cytoplasmic vesicle, Golgi apparatus, Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00001900531 – 758Golgin subfamily A member 1Add BLAST758

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Modified residuei30PhosphoserineCombined sources1
Modified residuei36PhosphoserineCombined sources1
Modified residuei41PhosphoserineCombined sources1
Modified residuei47PhosphoserineCombined sources1
Modified residuei50PhosphoserineBy similarity1
Modified residuei51PhosphoserineBy similarity1

Keywords - PTMi

Phosphoprotein

Proteomic databases

PaxDbiQ9CW79
PeptideAtlasiQ9CW79
PRIDEiQ9CW79

PTM databases

iPTMnetiQ9CW79
PhosphoSitePlusiQ9CW79

Expressioni

Developmental stagei

Present in the acrosome of spermatids up to the late cap-stage, but not in mature spermatozoa.

Gene expression databases

BgeeiENSMUSG00000026754 Expressed in 231 organ(s), highest expression level in utricle of membranous labyrinth
CleanExiMM_GOLGA1
ExpressionAtlasiQ9CW79 baseline and differential
GenevisibleiQ9CW79 MM

Interactioni

Subunit structurei

Interacts with RAB6A (By similarity). Directly interacts with TBC1D23 (PubMed:29084197). Interacts with FAM91A1; this interaction may mediated by TBC1D23 (Probable).By similarityCurated1 Publication

Protein-protein interaction databases

BioGridi218386, 1 interactor
IntActiQ9CW79, 5 interactors
MINTiQ9CW79
STRINGi10090.ENSMUSP00000037735

Structurei

3D structure databases

ProteinModelPortaliQ9CW79
SMRiQ9CW79
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini679 – 728GRIPPROSITE-ProRule annotationAdd BLAST50

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Coiled coili50 – 648Sequence analysisAdd BLAST599

Domaini

Extended rod-like protein with coiled-coil domains.

Keywords - Domaini

Coiled coil

Phylogenomic databases

eggNOGiENOG410IG17 Eukaryota
ENOG410ZJU1 LUCA
GeneTreeiENSGT00530000064371
HOGENOMiHOG000246957
HOVERGENiHBG051751
InParanoidiQ9CW79
KOiK16731
OMAiHVIVKFL
OrthoDBiEOG091G02ME
PhylomeDBiQ9CW79
TreeFamiTF326001

Family and domain databases

InterProiView protein in InterPro
IPR000237 GRIP_dom
PfamiView protein in Pfam
PF01465 GRIP, 1 hit
SMARTiView protein in SMART
SM00755 Grip, 1 hit
PROSITEiView protein in PROSITE
PS50913 GRIP, 1 hit

Sequences (2+)i

Sequence statusi: Complete.

This entry describes 2 isoformsi produced by alternative splicing. AlignAdd to basket

This entry has 2 described isoforms and 3 potential isoforms that are computationally mapped.Show allAlign All

Isoform 1 (identifier: Q9CW79-1) [UniParc]FASTAAdd to basket

This isoform has been chosen as the 'canonical' sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

« Hide
        10         20         30         40         50
MFAKLKKKIA EETAVAQRPG GTTRIPRSVS KESVASMGAD SGDDFASDGS
60 70 80 90 100
SSREDLSSQL LRRNEQIRKL EARLSDYAEQ VRNLQKIKEK LEIALEKHQD
110 120 130 140 150
SSMRKFQEQN ETFQASRAKM AEGLALALAR KDQEWSEKME QLEKDKRFLT
160 170 180 190 200
SQLQEVKNQS LSLFQKRDEI DELEGFQQQE ISKVKHMLLK KEECLGKMEQ
210 220 230 240 250
ELDARTRELN RTQEELVTSN QLSSDLNERL EELQRHCSTL EEQRDHLTAS
260 270 280 290 300
KAGAEHKIVV LEQKEQELQA IIQQHSIDLQ KVTAETQEKE KVITHLQEKV
310 320 330 340 350
IFLEKRLEQN LSGEDHVQEL LKEKTVAEQN LEDTRQQLLA ARNSHTKALY
360 370 380 390 400
LLETRVKDLE RSLQAAEEQL SQSRNVVADQ EAQIQKLITT NQENSLSQQQ
410 420 430 440 450
VLALEQHCRE RIHALEAQIE ALEQTRVADQ IASEQGMLQL QQENVALKES
460 470 480 490 500
RNECEHSLQH HQLELKKLKD EWSQREIVSV AMAQALEEVR KQREEFQQQA
510 520 530 540 550
TELTAIIEEK NQSLCEKDEA LLQKEQELRQ LEKGHSSALL QMHKLQRELE
560 570 580 590 600
ALKTCKAQEA MPATTGEDCL PLQGQEPLVI SKAMQNSEYE LPAAEGTPNG
610 620 630 640 650
EVGASDLKQL QKEKQDLEQQ LIEKNKIMKQ MQQRMLELKK TLQKELKIRP
660 670 680 690 700
DSELFEVREK TGPEIPNMAP SVTNNTDLTD AREINFEYLK HVVLKFMSCR
710 720 730 740 750
ESEAFHLIKA VSVLLNFSQE EENMLKETLE YKMSWFGSKP TPKGSIRPSI

SNPRIPWS
Length:758
Mass (Da):87,338
Last modified:July 3, 2003 - v2
Checksum:i5F2AECF0D91784D2
GO
Isoform 2 (identifier: Q9CW79-2) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     76-101: DYAEQVRNLQKIKEKLEIALEKHQDS → A

Note: No experimental confirmation available.
Show »
Length:733
Mass (Da):84,300
Checksum:i37C05CBFBA0ADE08
GO

Computationally mapped potential isoform sequencesi

There are 3 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
A0A0N4SVQ8A0A0N4SVQ8_MOUSE
Golgin subfamily A member 1
Golga1
186Annotation score:
A0A0N4SVV1A0A0N4SVV1_MOUSE
Golgin subfamily A member 1
Golga1
168Annotation score:
A0A0N4SVD1A0A0N4SVD1_MOUSE
Golgin subfamily A member 1
Golga1
82Annotation score:

Alternative sequence

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Alternative sequenceiVSP_00772676 – 101DYAEQ…KHQDS → A in isoform 2. 1 PublicationAdd BLAST26

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL844588 Genomic DNA No translation available.
BC043090 mRNA Translation: AAH43090.1
BC053068 mRNA Translation: AAH53068.1
AK002954 mRNA Translation: BAB22477.1
CCDSiCCDS16016.1 [Q9CW79-1]
CCDS71049.1 [Q9CW79-2]
RefSeqiNP_001277578.1, NM_001290649.1 [Q9CW79-2]
NP_084069.1, NM_029793.2 [Q9CW79-1]
UniGeneiMm.131098

Genome annotation databases

EnsembliENSMUST00000039165; ENSMUSP00000037735; ENSMUSG00000026754 [Q9CW79-1]
ENSMUST00000112850; ENSMUSP00000108471; ENSMUSG00000026754 [Q9CW79-2]
ENSMUST00000184996; ENSMUSP00000139001; ENSMUSG00000026754 [Q9CW79-1]
GeneIDi76899
KEGGimmu:76899
UCSCiuc008job.2 mouse [Q9CW79-1]
uc008joc.2 mouse [Q9CW79-2]

Keywords - Coding sequence diversityi

Alternative splicing

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL844588 Genomic DNA No translation available.
BC043090 mRNA Translation: AAH43090.1
BC053068 mRNA Translation: AAH53068.1
AK002954 mRNA Translation: BAB22477.1
CCDSiCCDS16016.1 [Q9CW79-1]
CCDS71049.1 [Q9CW79-2]
RefSeqiNP_001277578.1, NM_001290649.1 [Q9CW79-2]
NP_084069.1, NM_029793.2 [Q9CW79-1]
UniGeneiMm.131098

3D structure databases

ProteinModelPortaliQ9CW79
SMRiQ9CW79
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi218386, 1 interactor
IntActiQ9CW79, 5 interactors
MINTiQ9CW79
STRINGi10090.ENSMUSP00000037735

PTM databases

iPTMnetiQ9CW79
PhosphoSitePlusiQ9CW79

Proteomic databases

PaxDbiQ9CW79
PeptideAtlasiQ9CW79
PRIDEiQ9CW79

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSMUST00000039165; ENSMUSP00000037735; ENSMUSG00000026754 [Q9CW79-1]
ENSMUST00000112850; ENSMUSP00000108471; ENSMUSG00000026754 [Q9CW79-2]
ENSMUST00000184996; ENSMUSP00000139001; ENSMUSG00000026754 [Q9CW79-1]
GeneIDi76899
KEGGimmu:76899
UCSCiuc008job.2 mouse [Q9CW79-1]
uc008joc.2 mouse [Q9CW79-2]

Organism-specific databases

CTDi2800
MGIiMGI:1924149 Golga1

Phylogenomic databases

eggNOGiENOG410IG17 Eukaryota
ENOG410ZJU1 LUCA
GeneTreeiENSGT00530000064371
HOGENOMiHOG000246957
HOVERGENiHBG051751
InParanoidiQ9CW79
KOiK16731
OMAiHVIVKFL
OrthoDBiEOG091G02ME
PhylomeDBiQ9CW79
TreeFamiTF326001

Enzyme and pathway databases

ReactomeiR-MMU-6811440 Retrograde transport at the Trans-Golgi-Network

Miscellaneous databases

PROiPR:Q9CW79
SOURCEiSearch...

Gene expression databases

BgeeiENSMUSG00000026754 Expressed in 231 organ(s), highest expression level in utricle of membranous labyrinth
CleanExiMM_GOLGA1
ExpressionAtlasiQ9CW79 baseline and differential
GenevisibleiQ9CW79 MM

Family and domain databases

InterProiView protein in InterPro
IPR000237 GRIP_dom
PfamiView protein in Pfam
PF01465 GRIP, 1 hit
SMARTiView protein in SMART
SM00755 Grip, 1 hit
PROSITEiView protein in PROSITE
PS50913 GRIP, 1 hit
ProtoNetiSearch...

Entry informationi

Entry nameiGOGA1_MOUSE
AccessioniPrimary (citable) accession number: Q9CW79
Secondary accession number(s): A3KGQ9, Q80YB0
Entry historyiIntegrated into UniProtKB/Swiss-Prot: July 3, 2003
Last sequence update: July 3, 2003
Last modified: September 12, 2018
This is version 125 of the entry and version 2 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. MGD cross-references
    Mouse Genome Database (MGD) cross-references in UniProtKB/Swiss-Prot
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

We'd like to inform you that we have updated our Privacy Notice to comply with Europe’s new General Data Protection Regulation (GDPR) that applies since 25 May 2018.

Do not show this banner again