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Entry version 131 (12 Aug 2020)
Sequence version 2 (12 Dec 2006)
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Protein

Synaptonemal complex protein 2

Gene

Sycp2

Organism
Mus musculus (Mouse)
Status
Reviewed-Annotation score:

Annotation score:5 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Major component of the axial/lateral elements of synaptonemal complexes (SCS) during meiotic prophase. Plays a role in the assembly of synaptonemal complexes (PubMed:16717126). Required for normal meiotic chromosome synapsis during oocyte and spermatocyte development and for normal male and female fertility (PubMed:16717126). Required for insertion of SYCP3 into synaptonemal complexes (PubMed:16717126). May be involved in the organization of chromatin by temporarily binding to DNA scaffold attachment regions. Requires SYCP3, but not SYCP1, in order to be incorporated into the axial/lateral elements.2 Publications

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

GO - Biological processi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Molecular functionDNA-binding
Biological processCell cycle, Cell division, Meiosis

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Synaptonemal complex protein 2
Short name:
SCP-2
Alternative name(s):
Synaptonemal complex lateral element protein
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:Sycp2
Synonyms:Scp2
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiMus musculus (Mouse)
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri10090 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeMusMus
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000000589 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 2

Organism-specific databases

Mouse genome database (MGD) from Mouse Genome Informatics (MGI)

More...
MGIi
MGI:1933281, Sycp2

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte & Seán O’Donoghue; Source: COMPARTMENTS

Keywords - Cellular componenti

Chromosome, Nucleus

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

<p>This subsection of the 'Pathology and Biotech' section describes the in vivo effects caused by ablation of the gene (or one or more transcripts) coding for the protein described in the entry. This includes gene knockout and knockdown, provided experiments have been performed in the context of a whole organism or a specific tissue, and not at the single-cell level.<p><a href='/help/disruption_phenotype' target='_top'>More...</a></p>Disruption phenotypei

Mice appear healthy, but males are completely sterile, due to defective meiotic chromosome synapsis during spermatocyte development. Testes weight is much reduced in mutant mice. Females display reduced fertility.1 Publication

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'PTM / Processing' section describes the extent of a polypeptide chain in the mature protein following processing or proteolytic cleavage.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00000723671 – 1500Synaptonemal complex protein 2Add BLAST1500

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'PTM / Processing' section specifies the position and type of each modified residue excluding <a href="http://www.uniprot.org/manual/lipid">lipids</a>, <a href="http://www.uniprot.org/manual/carbohyd">glycans</a> and <a href="http://www.uniprot.org/manual/crosslnk">protein cross-links</a>.<p><a href='/help/mod_res' target='_top'>More...</a></p>Modified residuei457PhosphoserineCombined sources1
Modified residuei458PhosphoserineCombined sources1
Modified residuei464PhosphothreonineCombined sources1
Modified residuei487PhosphoserineCombined sources1
Modified residuei496PhosphothreonineCombined sources1
Modified residuei500PhosphoserineCombined sources1
Modified residuei509PhosphoserineCombined sources1
Modified residuei518PhosphoserineCombined sources1
Modified residuei527PhosphoserineCombined sources1
Modified residuei608PhosphothreonineCombined sources1
Modified residuei633PhosphothreonineCombined sources1
Modified residuei646PhosphoserineBy similarity1
Modified residuei650PhosphoserineCombined sources1
Modified residuei741PhosphoserineCombined sources1
Modified residuei914PhosphoserineCombined sources1
Modified residuei916PhosphothreonineCombined sources1
Modified residuei1115PhosphoserineCombined sources1
Modified residuei1117PhosphoserineCombined sources1
Modified residuei1124PhosphoserineCombined sources1
Modified residuei1133PhosphoserineCombined sources1
Modified residuei1140PhosphoserineCombined sources1
Modified residuei1144PhosphoserineCombined sources1
Modified residuei1156PhosphoserineCombined sources1
Modified residuei1159PhosphoserineCombined sources1
Modified residuei1164PhosphoserineCombined sources1
Modified residuei1168PhosphothreonineCombined sources1
Modified residuei1183PhosphoserineCombined sources1
Modified residuei1213PhosphoserineBy similarity1
Modified residuei1216PhosphoserineBy similarity1
Modified residuei1232PhosphoserineBy similarity1
Modified residuei1275PhosphoserineCombined sources1
Modified residuei1277PhosphoserineCombined sources1
Modified residuei1313PhosphothreonineCombined sources1

<p>This subsection of the <a href="http://www.uniprot.org/help/ptm%5Fprocessing%5Fsection">PTM/processing</a> section describes post-translational modifications (PTMs). This subsection <strong>complements</strong> the information provided at the sequence level or describes modifications for which <strong>position-specific data is not yet available</strong>.<p><a href='/help/post-translational_modification' target='_top'>More...</a></p>Post-translational modificationi

Phosphorylated.1 Publication

Keywords - PTMi

Phosphoprotein

Proteomic databases

PaxDb, a database of protein abundance averages across all three domains of life

More...
PaxDbi
Q9CUU3

PRoteomics IDEntifications database

More...
PRIDEi
Q9CUU3

PTM databases

iPTMnet integrated resource for PTMs in systems biology context

More...
iPTMneti
Q9CUU3

Comprehensive resource for the study of protein post-translational modifications (PTMs) in human, mouse and rat.

More...
PhosphoSitePlusi
Q9CUU3

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

<p>This subsection of the 'Expression' section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms. By default, the information is derived from experiments at the mRNA level, unless specified 'at protein level'.<br></br>Examples: <a href="http://www.uniprot.org/uniprot/P92958#expression">P92958</a>, <a href="http://www.uniprot.org/uniprot/Q8TDN4#expression">Q8TDN4</a>, <a href="http://www.uniprot.org/uniprot/O14734#expression">O14734</a><p><a href='/help/tissue_specificity' target='_top'>More...</a></p>Tissue specificityi

Detected in testis and spermatocytes (at protein level).1 Publication

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...
Bgeei
ENSMUSG00000060445, Expressed in testis and 86 other tissues

ExpressionAtlas, Differential and Baseline Expression

More...
ExpressionAtlasi
Q9CUU3, baseline and differential

Genevisible search portal to normalized and curated expression data from Genevestigator

More...
Genevisiblei
Q9CUU3, MM

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

<p>This subsection of the <a href="http://www.uniprot.org/help/interaction%5Fsection">'Interaction'</a> section provides information about the protein quaternary structure and interaction(s) with other proteins or protein complexes (with the exception of physiological receptor-ligand interactions which are annotated in the <a href="http://www.uniprot.org/help/function%5Fsection">'Function'</a> section).<p><a href='/help/subunit_structure' target='_top'>More...</a></p>Subunit structurei

Component of the lateral elements of synaptonemal complexes (PubMed:16717126). Heterodimer with SYCP3 (PubMed:16717126).

Interacts with SMC1A and SMC3 (By similarity).

Interacts with TEX11 (PubMed:18316482).

By similarity2 Publications

Protein-protein interaction databases

The Biological General Repository for Interaction Datasets (BioGRID)

More...
BioGRIDi
236115, 3 interactors

CORUM comprehensive resource of mammalian protein complexes

More...
CORUMi
Q9CUU3

Protein interaction database and analysis system

More...
IntActi
Q9CUU3, 1 interactor

Molecular INTeraction database

More...
MINTi
Q9CUU3

STRING: functional protein association networks

More...
STRINGi
10090.ENSMUSP00000079909

Miscellaneous databases

RNAct, Protein-RNA interaction predictions for model organisms.

More...
RNActi
Q9CUU3, protein

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

Secondary structure

11500
Legend: HelixTurnBeta strandPDB Structure known for this area
Show more details

3D structure databases

SWISS-MODEL Repository - a database of annotated 3D protein structure models

More...
SMRi
Q9CUU3

Database of comparative protein structure models

More...
ModBasei
Search...

Protein Data Bank in Europe - Knowledge Base

More...
PDBe-KBi
Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and domains' section denotes the positions of regions of coiled coil within the protein.<p><a href='/help/coiled' target='_top'>More...</a></p>Coiled coili1388 – 1429Sequence analysisAdd BLAST42

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes the position of regions of compositional bias within the protein and the particular amino acids that are over-represented within those regions.<p><a href='/help/compbias' target='_top'>More...</a></p>Compositional biasi1080 – 1090Poly-SerAdd BLAST11

<p>This subsection of the 'Family and domains' section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Belongs to the SYCP2 family.Curated

Keywords - Domaini

Coiled coil

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
ENOG502QVM5, Eukaryota

Ensembl GeneTree

More...
GeneTreei
ENSGT00530000063859

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...
HOGENOMi
CLU_004101_0_0_1

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
Q9CUU3

KEGG Orthology (KO)

More...
KOi
K19529

Identification of Orthologs from Complete Genome Data

More...
OMAi
MAHERNV

Database of Orthologous Groups

More...
OrthoDBi
285929at2759

TreeFam database of animal gene trees

More...
TreeFami
TF332368

Family and domain databases

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR024835, SYCP1/2
IPR024832, SYCP2
IPR041322, SYCP2_ARLD
IPR040560, SYCP2_SLD

The PANTHER Classification System

More...
PANTHERi
PTHR15607, PTHR15607, 1 hit
PTHR15607:SF12, PTHR15607:SF12, 1 hit

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF18581, SYCP2_ARLD, 1 hit
PF18584, SYCP2_SLD, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequence (1+)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

This entry has 1 described isoform and 1 potential isoform that is computationally mapped.Show allAlign All

Q9CUU3-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MPVRPDLQQL EKCIDDALRK NDFKPLLALL QIDICEDVKI KCSKQFLRKL
60 70 80 90 100
DDLICRELNK KDIQTVSSIL ISIGRCSKNI FILGQAGLQT MIKQGLVQKM
110 120 130 140 150
VSWFENSKEI ILNQQQSKDE AVMNMIEDLF DLLMVIYDIS DEGKNQVLES
160 170 180 190 200
FIPQICALVI DSRVNFCIQQ EALKKMNLML DRIPQDANKI LSNQEMLTLM
210 220 230 240 250
SNMGERILDV GDYELQVGIV EALCRMTTEK RRQELAYEWF SMDFIANAFK
260 270 280 290 300
EIKDCEFETD CRIFLNLVNG ILGDKRRVYT FPCLSAFLGK YELQIPSDEK
310 320 330 340 350
LEEFWIDFNL GSHTLSFYIA GDEEDHQWEA VTVPEEKVQM YNIEVRESKK
360 370 380 390 400
LLTLTLKNIV KISKKEGKEL LFYFDESLEI TNVTKKVFGG NKYKEFTRKQ
410 420 430 440 450
GISVAKTSIH VLFDASGSQI LVPESQPSPV KENLIHLKEK SDIQKKLVNP
460 470 480 490 500
LELGNSSSQD EITTPSRKKM SEASMIVPDT DRYTVRSPIL LINTSTPRRS
510 520 530 540 550
REPLQAINSV EKAVSKTSES GMDYAASPKS RQSDGRKRWN NRANHNKTTA
560 570 580 590 600
VIQNKQYEDN ESPDQNFNEI EDTLSNVSSA VGKVDKPVLP GVLDISKNTT
610 620 630 640 650
HSRWACWTPV TTIKLCNNQR SRALPGDTCT QDTGVNKKCT KQKSVSDDDS
660 670 680 690 700
EETQKGKYSK DVIKCNKSDE AEFCERNIQE QNHPKYSQKK NTANAKKSDW
710 720 730 740 750
HIESETTYKS VLLNKTTEES LIYKKTCVLS KDVNTTICDK SPSRKSKRNH
760 770 780 790 800
TKSRKELMSE LTSCELEEIP VRENSKGKRF TGASESLINQ ISRRYNPSDS
810 820 830 840 850
MMSTRKLKEP QDGSGFSKKP DLQFNKVQRK SYRKLKATVV NVTSECPLDD
860 870 880 890 900
VYNFSLNGAD EPVIKLGIQE FQATTREASM DNSLKLVKNH DEHDPFLKTK
910 920 930 940 950
DKRMLSYEKK TLLSDTETEC GCDDSKTDIS WLKEPKTKRL MDYSRNKNTT
960 970 980 990 1000
KYKSRKSRSS MEKGQPRPTM VLNKNSMKND YEVVVDGRTR LPRRATKTKK
1010 1020 1030 1040 1050
NYKDLSTSES ESESEKECSY LFKDKLPTKE ETIHSRAQTK KLPEKQQKVF
1060 1070 1080 1090 1100
NSEALKGQPS EEQKNSSRLR EGREDSLCLS SASVSRSSSS VEVMRCTEKI
1110 1120 1130 1140 1150
TERDFTQDYD YITKSLSPYP KAPSPEFLNG NNSVVGRGQS PRISETSAMC
1160 1170 1180 1190 1200
VRKSYSPASG PPFSPRHTPT KNNSVVNMKK ANSVINNQRT QHCNSYSDVS
1210 1220 1230 1240 1250
SNSSEKLYME PESPESCDNH MQNKREGNHA ASPLSLSSEK IEKMWFDMPS
1260 1270 1280 1290 1300
ENTHVSGPSQ RGSKRRMYLE DDELSNSNEA EVEEAEEREH LLSKKRCQWE
1310 1320 1330 1340 1350
NSDQHTFKTS LSTPDFSVPK DWQQELQGAG MFYDNISSDY KRKTDSQHKI
1360 1370 1380 1390 1400
MDDFTTKTLK LTQQHLMAMT SQAQGRRDEN VEKFQVTLLD ELEKVEKDSQ
1410 1420 1430 1440 1450
TLRDLEKELV DIEEKLVQKM RAYHRCERER FRVLKTSLDK SFLVYNSVYE
1460 1470 1480 1490 1500
ESVFTSEMCL MKANMKMLQD KLLKEMHEEE VLNIRRGLQS LFKAHEGNDA
Length:1,500
Mass (Da):172,123
Last modified:December 12, 2006 - v2
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i3706CF5214C51829
GO

<p>In eukaryotic reference proteomes, unreviewed entries that are likely to belong to the same gene are computationally mapped, based on gene identifiers from Ensembl, EnsemblGenomes and model organism databases.<p><a href='/help/gene_centric_isoform_mapping' target='_top'>More...</a></p>Computationally mapped potential isoform sequencesi

There is 1 potential isoform mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
A2AJW3A2AJW3_MOUSE
Synaptonemal complex protein 2
Sycp2
185Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>

<p>This subsection of the 'Sequence' section reports difference(s) between the protein sequence shown in the UniProtKB entry and other available protein sequences derived from the same gene.<p><a href='/help/sequence_caution' target='_top'>More...</a></p>Sequence cautioni

The sequence AK014411 differs from that shown. Intron retention.Curated

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

More...
GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
DQ103262 mRNA Translation: AAZ80470.1
AL772217 Genomic DNA No translation available.
AK014411 mRNA No translation available.

The Consensus CDS (CCDS) project

More...
CCDSi
CCDS38370.1

NCBI Reference Sequences

More...
RefSeqi
NP_796165.2, NM_177191.3
XP_017174510.1, XM_017319021.1

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...
Ensembli
ENSMUST00000081134; ENSMUSP00000079909; ENSMUSG00000060445

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
320558

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
mmu:320558

UCSC genome browser

More...
UCSCi
uc008ohn.1, mouse

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
DQ103262 mRNA Translation: AAZ80470.1
AL772217 Genomic DNA No translation available.
AK014411 mRNA No translation available.
CCDSiCCDS38370.1
RefSeqiNP_796165.2, NM_177191.3
XP_017174510.1, XM_017319021.1

3D structure databases

Select the link destinations:

Protein Data Bank Europe

More...
PDBei

Protein Data Bank RCSB

More...
RCSB PDBi

Protein Data Bank Japan

More...
PDBji
Links Updated
PDB entryMethodResolution (Å)ChainPositionsPDBsum
5IWZX-ray2.10A1-390[»]
SMRiQ9CUU3
ModBaseiSearch...
PDBe-KBiSearch...

Protein-protein interaction databases

BioGRIDi236115, 3 interactors
CORUMiQ9CUU3
IntActiQ9CUU3, 1 interactor
MINTiQ9CUU3
STRINGi10090.ENSMUSP00000079909

PTM databases

iPTMnetiQ9CUU3
PhosphoSitePlusiQ9CUU3

Proteomic databases

PaxDbiQ9CUU3
PRIDEiQ9CUU3

Protocols and materials databases

Antibodypedia a portal for validated antibodies

More...
Antibodypediai
58383, 90 antibodies

Genome annotation databases

EnsembliENSMUST00000081134; ENSMUSP00000079909; ENSMUSG00000060445
GeneIDi320558
KEGGimmu:320558
UCSCiuc008ohn.1, mouse

Organism-specific databases

Comparative Toxicogenomics Database

More...
CTDi
10388
MGIiMGI:1933281, Sycp2

Phylogenomic databases

eggNOGiENOG502QVM5, Eukaryota
GeneTreeiENSGT00530000063859
HOGENOMiCLU_004101_0_0_1
InParanoidiQ9CUU3
KOiK19529
OMAiMAHERNV
OrthoDBi285929at2759
TreeFamiTF332368

Miscellaneous databases

BioGRID ORCS database of CRISPR phenotype screens

More...
BioGRID-ORCSi
320558, 1 hit in 18 CRISPR screens

ChiTaRS: a database of human, mouse and fruit fly chimeric transcripts and RNA-sequencing data

More...
ChiTaRSi
Scp2, mouse

Protein Ontology

More...
PROi
PR:Q9CUU3
RNActiQ9CUU3, protein

The Stanford Online Universal Resource for Clones and ESTs

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SOURCEi
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Gene expression databases

BgeeiENSMUSG00000060445, Expressed in testis and 86 other tissues
ExpressionAtlasiQ9CUU3, baseline and differential
GenevisibleiQ9CUU3, MM

Family and domain databases

InterProiView protein in InterPro
IPR024835, SYCP1/2
IPR024832, SYCP2
IPR041322, SYCP2_ARLD
IPR040560, SYCP2_SLD
PANTHERiPTHR15607, PTHR15607, 1 hit
PTHR15607:SF12, PTHR15607:SF12, 1 hit
PfamiView protein in Pfam
PF18581, SYCP2_ARLD, 1 hit
PF18584, SYCP2_SLD, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

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ProtoNeti
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MobiDB: a database of protein disorder and mobility annotations

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MobiDBi
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<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiSYCP2_MOUSE
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q9CUU3
Secondary accession number(s): A2AJW2, Q1G7B6
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: October 10, 2002
Last sequence update: December 12, 2006
Last modified: August 12, 2020
This is version 131 of the entry and version 2 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

3D-structure, Reference proteome

Documents

  1. MGD cross-references
    Mouse Genome Database (MGD) cross-references in UniProtKB/Swiss-Prot
  2. PDB cross-references
    Index of Protein Data Bank (PDB) cross-references
  3. SIMILARITY comments
    Index of protein domains and families
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