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Protein

Dysbindin domain-containing protein 2

Gene

Dbndd2

Organism
Mus musculus (Mouse)
Status
Reviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

May modulate the activity of casein kinase-1. Inhibits CSNK1D autophosphorylation (in vitro) (By similarity).By similarity

GO - Biological processi

Names & Taxonomyi

Protein namesi
Recommended name:
Dysbindin domain-containing protein 2
Gene namesi
Name:Dbndd2
Synonyms:D2Bwg0891e
OrganismiMus musculus (Mouse)
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeMusMus
Proteomesi
  • UP000000589 Componenti: Chromosome 2

Organism-specific databases

MGIiMGI:106562 Dbndd2

Subcellular locationi

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00001910041 – 158Dysbindin domain-containing protein 2Add BLAST158

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Modified residuei119PhosphoserineCombined sources1
Modified residuei120PhosphoserineCombined sources1
Modified residuei137PhosphothreonineCombined sources1
Modified residuei142PhosphoserineCombined sources1

Keywords - PTMi

Phosphoprotein

Proteomic databases

PaxDbiQ9CRD4
PRIDEiQ9CRD4

PTM databases

iPTMnetiQ9CRD4
PhosphoSitePlusiQ9CRD4

Expressioni

Gene expression databases

BgeeiENSMUSG00000017734 Expressed in 185 organ(s), highest expression level in lumbar subsegment of spinal cord
ExpressionAtlasiQ9CRD4 baseline and differential
GenevisibleiQ9CRD4 MM

Interactioni

Subunit structurei

Monomer. Interacts with CSNK1D and CSNK1E (By similarity).By similarity

Structurei

3D structure databases

ProteinModelPortaliQ9CRD4
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the dysbindin family.Curated

Phylogenomic databases

eggNOGiENOG410IZAY Eukaryota
ENOG4111ACH LUCA
GeneTreeiENSGT00390000010667
HOGENOMiHOG000112170
HOVERGENiHBG056909
InParanoidiQ9CRD4
OMAiQTSGVDD
OrthoDBiEOG091G0ZXL
PhylomeDBiQ9CRD4

Family and domain databases

InterProiView protein in InterPro
IPR007531 Dysbindin
PANTHERiPTHR16294 PTHR16294, 1 hit
PfamiView protein in Pfam
PF04440 Dysbindin, 1 hit

Sequence (1+)i

Sequence statusi: Complete.

This entry has 1 described isoform and 1 potential isoform that is computationally mapped.Show allAlign All

Q9CRD4-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MDPNPRAALE RQQLRLRERQ KFFEDILQPE TEFVFPLSHL HLESQRPPIG
60 70 80 90 100
SISSMEVNVD TLEQVEFIDL ADQDGADVFL PCEESSPAPQ MSGVDDHPEE
110 120 130 140 150
LSLLVPTSDR TTSRTSSLSS DSSNLRSPNP SDGGGDTPLA QSDEEDGDDG

GAEPGPCS
Length:158
Mass (Da):17,194
Last modified:June 1, 2001 - v1
Checksum:i00250676CE25DF7E
GO

Computationally mapped potential isoform sequencesi

There is 1 potential isoform mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
A2A5G0A2A5G0_MOUSE
Dysbindin domain-containing protein...
Dbndd2
119Annotation score:

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK013571 mRNA Translation: BAB28911.1
AK003735 mRNA Translation: BAB22969.1
BC019947 mRNA Translation: AAH19947.1
BC030298 mRNA Translation: AAH30298.1
CCDSiCCDS38322.1
RefSeqiNP_001041692.1, NM_001048227.1
NP_001041693.1, NM_001048228.1
NP_001041694.1, NM_001048229.1
NP_081073.1, NM_026797.2
XP_006499958.1, XM_006499895.3
UniGeneiMm.256927

Genome annotation databases

EnsembliENSMUST00000017878; ENSMUSP00000017878; ENSMUSG00000017734
ENSMUST00000069385; ENSMUSP00000064437; ENSMUSG00000017734
ENSMUST00000109349; ENSMUSP00000104973; ENSMUSG00000017734
ENSMUST00000109350; ENSMUSP00000104974; ENSMUSG00000017734
ENSMUST00000149287; ENSMUSP00000128551; ENSMUSG00000017734
GeneIDi52840
KEGGimmu:52840
UCSCiuc008nuw.1 mouse

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK013571 mRNA Translation: BAB28911.1
AK003735 mRNA Translation: BAB22969.1
BC019947 mRNA Translation: AAH19947.1
BC030298 mRNA Translation: AAH30298.1
CCDSiCCDS38322.1
RefSeqiNP_001041692.1, NM_001048227.1
NP_001041693.1, NM_001048228.1
NP_001041694.1, NM_001048229.1
NP_081073.1, NM_026797.2
XP_006499958.1, XM_006499895.3
UniGeneiMm.256927

3D structure databases

ProteinModelPortaliQ9CRD4
ModBaseiSearch...
MobiDBiSearch...

PTM databases

iPTMnetiQ9CRD4
PhosphoSitePlusiQ9CRD4

Proteomic databases

PaxDbiQ9CRD4
PRIDEiQ9CRD4

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSMUST00000017878; ENSMUSP00000017878; ENSMUSG00000017734
ENSMUST00000069385; ENSMUSP00000064437; ENSMUSG00000017734
ENSMUST00000109349; ENSMUSP00000104973; ENSMUSG00000017734
ENSMUST00000109350; ENSMUSP00000104974; ENSMUSG00000017734
ENSMUST00000149287; ENSMUSP00000128551; ENSMUSG00000017734
GeneIDi52840
KEGGimmu:52840
UCSCiuc008nuw.1 mouse

Organism-specific databases

CTDi55861
MGIiMGI:106562 Dbndd2

Phylogenomic databases

eggNOGiENOG410IZAY Eukaryota
ENOG4111ACH LUCA
GeneTreeiENSGT00390000010667
HOGENOMiHOG000112170
HOVERGENiHBG056909
InParanoidiQ9CRD4
OMAiQTSGVDD
OrthoDBiEOG091G0ZXL
PhylomeDBiQ9CRD4

Miscellaneous databases

ChiTaRSiDbndd2 mouse
PROiPR:Q9CRD4
SOURCEiSearch...

Gene expression databases

BgeeiENSMUSG00000017734 Expressed in 185 organ(s), highest expression level in lumbar subsegment of spinal cord
ExpressionAtlasiQ9CRD4 baseline and differential
GenevisibleiQ9CRD4 MM

Family and domain databases

InterProiView protein in InterPro
IPR007531 Dysbindin
PANTHERiPTHR16294 PTHR16294, 1 hit
PfamiView protein in Pfam
PF04440 Dysbindin, 1 hit
ProtoNetiSearch...

Entry informationi

Entry nameiDBND2_MOUSE
AccessioniPrimary (citable) accession number: Q9CRD4
Entry historyiIntegrated into UniProtKB/Swiss-Prot: July 11, 2003
Last sequence update: June 1, 2001
Last modified: November 7, 2018
This is version 107 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families
  2. MGD cross-references
    Mouse Genome Database (MGD) cross-references in UniProtKB/Swiss-Prot
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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