Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein

NADH dehydrogenase [ubiquinone] 1 subunit C1, mitochondrial

Gene

Ndufc1

Organism
Mus musculus (Mouse)
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.By similarity

GO - Biological processi

Keywordsi

Biological processElectron transport, Respiratory chain, Transport

Enzyme and pathway databases

ReactomeiR-MMU-611105 Respiratory electron transport
R-MMU-6799198 Complex I biogenesis

Names & Taxonomyi

Protein namesi
Recommended name:
NADH dehydrogenase [ubiquinone] 1 subunit C1, mitochondrial
Alternative name(s):
Complex I-KFYI
Short name:
CI-KFYI
NADH-ubiquinone oxidoreductase KFYI subunit
Gene namesi
Name:Ndufc1
OrganismiMus musculus (Mouse)
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeMusMus
Proteomesi
  • UP000000589 Componenti: Chromosome 3

Organism-specific databases

MGIiMGI:1913627 Ndufc1

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei40 – 59HelicalSequence analysisAdd BLAST20

Keywords - Cellular componenti

Membrane, Mitochondrion, Mitochondrion inner membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transit peptidei1 – 27MitochondrionBy similarityAdd BLAST27
ChainiPRO_000002005028 – 76NADH dehydrogenase [ubiquinone] 1 subunit C1, mitochondrialAdd BLAST49

Proteomic databases

MaxQBiQ9CQY9
PaxDbiQ9CQY9
PRIDEiQ9CQY9
TopDownProteomicsiQ9CQY9

Expressioni

Gene expression databases

BgeeiENSMUSG00000037152
GenevisibleiQ9CQY9 MM

Interactioni

Subunit structurei

Complex I is composed of 45 different subunits.By similarity

Protein-protein interaction databases

ComplexPortaliCPX-266 Mitochondrial respiratory chain complex I
STRINGi10090.ENSMUSP00000038463

Structurei

3D structure databases

SMRiQ9CQY9
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the complex I NDUFC1 subunit family.Curated

Keywords - Domaini

Transit peptide, Transmembrane, Transmembrane helix

Phylogenomic databases

eggNOGiENOG410J0MG Eukaryota
ENOG410XUGS LUCA
GeneTreeiENSGT00390000002565
HOGENOMiHOG000013086
HOVERGENiHBG006500
InParanoidiQ9CQY9
KOiK03967
OMAiNAKPDWL
OrthoDBiEOG091G14QE
PhylomeDBiQ9CQY9
TreeFamiTF338333

Family and domain databases

InterProiView protein in InterPro
IPR026192 NDUFC1
PANTHERiPTHR17097 PTHR17097, 1 hit
PfamiView protein in Pfam
PF15088 NADH_dh_m_C1, 1 hit

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

Q9CQY9-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MAPSVVLRSF SRLLAPARLP SCSSTRSKFY VREPVNAKPN WLAVGLSVGA
60 70
SVFMWIYLIQ THNEDVLEYK RRNGLE
Length:76
Mass (Da):8,625
Last modified:June 1, 2001 - v1
Checksum:i3EF9EE9B8D2367F8
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK003365 mRNA Translation: BAB22739.1
AK009393 mRNA Translation: BAB26262.1
AK018705 mRNA Translation: BAB31356.1
AK028011 mRNA Translation: BAC25698.1
BC092141 mRNA Translation: AAH92141.1
CCDSiCCDS38426.1
RefSeqiNP_079799.1, NM_025523.1
UniGeneiMm.331007

Genome annotation databases

EnsembliENSMUST00000038108; ENSMUSP00000038463; ENSMUSG00000037152
ENSMUST00000193279; ENSMUSP00000141933; ENSMUSG00000037152
GeneIDi66377
KEGGimmu:66377
UCSCiuc008pdy.1 mouse

Similar proteinsi

Entry informationi

Entry nameiNDUC1_MOUSE
AccessioniPrimary (citable) accession number: Q9CQY9
Secondary accession number(s): Q58DY9
Entry historyiIntegrated into UniProtKB/Swiss-Prot: May 10, 2004
Last sequence update: June 1, 2001
Last modified: June 20, 2018
This is version 108 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. MGD cross-references
    Mouse Genome Database (MGD) cross-references in UniProtKB/Swiss-Prot
  2. SIMILARITY comments
    Index of protein domains and families

We'd like to inform you that we have updated our Privacy Notice to comply with Europe’s new General Data Protection Regulation (GDPR) that applies since 25 May 2018.

Do not show this banner again
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health