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Protein

Galectin-2

Gene

Lgals2

Organism
Mus musculus (Mouse)
Status
Reviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

This protein binds beta-galactoside. Its physiological function is not yet known.

GO - Molecular functioni

Keywordsi

LigandLectin

Names & Taxonomyi

Protein namesi
Recommended name:
Galectin-2
Short name:
Gal-2
Gene namesi
Name:Lgals2
OrganismiMus musculus (Mouse)
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeMusMus
Proteomesi
  • UP000000589 Componenti: Chromosome 15

Organism-specific databases

MGIiMGI:895068 Lgals2

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00000769251 – 130Galectin-2Add BLAST130

Proteomic databases

MaxQBiQ9CQW5
PaxDbiQ9CQW5
PeptideAtlasiQ9CQW5
PRIDEiQ9CQW5

PTM databases

PhosphoSitePlusiQ9CQW5

Expressioni

Gene expression databases

BgeeiENSMUSG00000043501 Expressed in 76 organ(s), highest expression level in mucous cell of stomach
CleanExiMM_LGALS2
GenevisibleiQ9CQW5 MM

Interactioni

Subunit structurei

Homodimer.By similarity

Protein-protein interaction databases

ComplexPortaliCPX-96 Galectin-2 complex
IntActiQ9CQW5, 3 interactors
STRINGi10090.ENSMUSP00000036598

Structurei

3D structure databases

ProteinModelPortaliQ9CQW5
SMRiQ9CQW5
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini4 – 130GalectinPROSITE-ProRule annotationAdd BLAST127

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Regioni65 – 71Beta-galactoside bindingSequence analysis7

Phylogenomic databases

eggNOGiKOG3587 Eukaryota
ENOG4111EA0 LUCA
GeneTreeiENSGT00440000034263
HOGENOMiHOG000059539
HOVERGENiHBG006255
InParanoidiQ9CQW5
KOiK10090
OMAiVCNSRDG
OrthoDBiEOG091G0S7H
PhylomeDBiQ9CQW5
TreeFamiTF315551

Family and domain databases

CDDicd00070 GLECT, 1 hit
InterProiView protein in InterPro
IPR013320 ConA-like_dom_sf
IPR001079 Galectin_CRD
PfamiView protein in Pfam
PF00337 Gal-bind_lectin, 1 hit
SMARTiView protein in SMART
SM00908 Gal-bind_lectin, 1 hit
SM00276 GLECT, 1 hit
SUPFAMiSSF49899 SSF49899, 1 hit
PROSITEiView protein in PROSITE
PS51304 GALECTIN, 1 hit

Sequencei

Sequence statusi: Complete.

Q9CQW5-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MSEKFEVKDL NMKPGMSLKI KGKIHNDVDR FLINLGQGKE TLNLHFNPRF
60 70 80 90 100
DESTIVCNTS EGGRWGQEQR ENHMCFSPGS EVKITITFQD KDFKVTLPDG
110 120 130
HQLTFPNRLG HNQLHYLSMG GLQISSFKLE
Length:130
Mass (Da):14,880
Last modified:April 27, 2001 - v1
Checksum:i4E5EA89F3E0C36FD
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Sequence conflicti36G → V in BAB25806 (PubMed:16141072).Curated1
Sequence conflicti106P → R in BAB25661 (PubMed:16141072).Curated1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK007364 mRNA Translation: BAB24987.1
AK008423 mRNA Translation: BAB25661.1
AK008636 mRNA Translation: BAB25797.1
AK008648 mRNA Translation: BAB25806.1
CCDSiCCDS37135.1
RefSeqiNP_079898.2, NM_025622.3
UniGeneiMm.390793

Genome annotation databases

EnsembliENSMUST00000044584; ENSMUSP00000036598; ENSMUSG00000043501
GeneIDi107753
KEGGimmu:107753
UCSCiuc007wrm.2 mouse

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK007364 mRNA Translation: BAB24987.1
AK008423 mRNA Translation: BAB25661.1
AK008636 mRNA Translation: BAB25797.1
AK008648 mRNA Translation: BAB25806.1
CCDSiCCDS37135.1
RefSeqiNP_079898.2, NM_025622.3
UniGeneiMm.390793

3D structure databases

ProteinModelPortaliQ9CQW5
SMRiQ9CQW5
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

ComplexPortaliCPX-96 Galectin-2 complex
IntActiQ9CQW5, 3 interactors
STRINGi10090.ENSMUSP00000036598

PTM databases

PhosphoSitePlusiQ9CQW5

Proteomic databases

MaxQBiQ9CQW5
PaxDbiQ9CQW5
PeptideAtlasiQ9CQW5
PRIDEiQ9CQW5

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSMUST00000044584; ENSMUSP00000036598; ENSMUSG00000043501
GeneIDi107753
KEGGimmu:107753
UCSCiuc007wrm.2 mouse

Organism-specific databases

CTDi3957
MGIiMGI:895068 Lgals2

Phylogenomic databases

eggNOGiKOG3587 Eukaryota
ENOG4111EA0 LUCA
GeneTreeiENSGT00440000034263
HOGENOMiHOG000059539
HOVERGENiHBG006255
InParanoidiQ9CQW5
KOiK10090
OMAiVCNSRDG
OrthoDBiEOG091G0S7H
PhylomeDBiQ9CQW5
TreeFamiTF315551

Miscellaneous databases

PROiPR:Q9CQW5
SOURCEiSearch...

Gene expression databases

BgeeiENSMUSG00000043501 Expressed in 76 organ(s), highest expression level in mucous cell of stomach
CleanExiMM_LGALS2
GenevisibleiQ9CQW5 MM

Family and domain databases

CDDicd00070 GLECT, 1 hit
InterProiView protein in InterPro
IPR013320 ConA-like_dom_sf
IPR001079 Galectin_CRD
PfamiView protein in Pfam
PF00337 Gal-bind_lectin, 1 hit
SMARTiView protein in SMART
SM00908 Gal-bind_lectin, 1 hit
SM00276 GLECT, 1 hit
SUPFAMiSSF49899 SSF49899, 1 hit
PROSITEiView protein in PROSITE
PS51304 GALECTIN, 1 hit
ProtoNetiSearch...

Entry informationi

Entry nameiLEG2_MOUSE
AccessioniPrimary (citable) accession number: Q9CQW5
Secondary accession number(s): Q9D800, Q9D862
Entry historyiIntegrated into UniProtKB/Swiss-Prot: April 27, 2001
Last sequence update: April 27, 2001
Last modified: November 7, 2018
This is version 117 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. MGD cross-references
    Mouse Genome Database (MGD) cross-references in UniProtKB/Swiss-Prot
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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