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Protein

Nicolin-1

Gene

Nicn1

Organism
Mus musculus (Mouse)
Status
Reviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

GO - Biological processi

Names & Taxonomyi

Protein namesi
Recommended name:
Nicolin-1
Alternative name(s):
Tubulin polyglutamylase complex subunit 5
Short name:
PGs5
p24
Gene namesi
Name:Nicn1
OrganismiMus musculus (Mouse)
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeMusMus
Proteomesi
  • UP000000589 Componenti: Chromosome 9

Organism-specific databases

MGIiMGI:1913507 Nicn1

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

Microtubule, Nucleus

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00000968151 – 213Nicolin-1Add BLAST213

Proteomic databases

MaxQBiQ9CQM0
PaxDbiQ9CQM0
PRIDEiQ9CQM0

PTM databases

iPTMnetiQ9CQM0
PhosphoSitePlusiQ9CQM0

Expressioni

Tissue specificityi

High expression level is found in brain, testis, liver and kidney. Weak expression in spleen, leukocytes, small intestin and colon.1 Publication

Developmental stagei

Detected in all tissues of the developing embryos.1 Publication

Gene expression databases

BgeeiENSMUSG00000032606 Expressed in 272 organ(s), highest expression level in ear
GenevisibleiQ9CQM0 MM

Interactioni

Subunit structurei

Part of the neuronal tubulin polyglutamylase complex which contains TPGS1, TPGS2, TTLL1, LRRC49 and NICN1.

Protein-protein interaction databases

CORUMiQ9CQM0

Family & Domainsi

Phylogenomic databases

eggNOGiENOG410IHPW Eukaryota
ENOG4111GDK LUCA
GeneTreeiENSGT00390000001505
HOGENOMiHOG000006705
HOVERGENiHBG052619
InParanoidiQ9CQM0
KOiK16607
OMAiCEQPAPL
OrthoDBiEOG091G0NXM
PhylomeDBiQ9CQM0
TreeFamiTF329753

Sequencei

Sequence statusi: Complete.

Q9CQM0-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MSRVLVPCHV KSTVALQVGD MRTSQGRPGV LVVDVTFPNI APFELQEIMF
60 70 80 90 100
KNYYTAFLSI RVRQQSSMHT AAKWVTCLRD YCLMPDPHSE EGAQDYVSLF
110 120 130 140 150
KHQMLCDMNR VLELRLILRQ PSPLWLSFTV EELQIYQQGP KSPSLAFPKW
160 170 180 190 200
LSHPVSNEQP APRLEGLPDP SRVSSEVQQM WALTEMIRAS HTSTRIGRFD
210
VDGCYDLNLL SYT
Length:213
Mass (Da):24,360
Last modified:June 1, 2001 - v1
Checksum:i780F341FBA357173
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AJ299741 mRNA Translation: CAC82517.1
AJ437692 Genomic DNA Translation: CAD26916.1
AK002789 mRNA Translation: BAB22360.1
AK013602 mRNA Translation: BAB28922.1
AK075732 mRNA Translation: BAC35916.1
BC024050 mRNA Translation: AAH24050.1
CCDSiCCDS40767.1
RefSeqiNP_079725.1, NM_025449.3
UniGeneiMm.10407

Genome annotation databases

EnsembliENSMUST00000035227; ENSMUSP00000035227; ENSMUSG00000032606
GeneIDi66257
KEGGimmu:66257
UCSCiuc009rpb.1 mouse

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AJ299741 mRNA Translation: CAC82517.1
AJ437692 Genomic DNA Translation: CAD26916.1
AK002789 mRNA Translation: BAB22360.1
AK013602 mRNA Translation: BAB28922.1
AK075732 mRNA Translation: BAC35916.1
BC024050 mRNA Translation: AAH24050.1
CCDSiCCDS40767.1
RefSeqiNP_079725.1, NM_025449.3
UniGeneiMm.10407

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

CORUMiQ9CQM0

PTM databases

iPTMnetiQ9CQM0
PhosphoSitePlusiQ9CQM0

Proteomic databases

MaxQBiQ9CQM0
PaxDbiQ9CQM0
PRIDEiQ9CQM0

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSMUST00000035227; ENSMUSP00000035227; ENSMUSG00000032606
GeneIDi66257
KEGGimmu:66257
UCSCiuc009rpb.1 mouse

Organism-specific databases

CTDi84276
MGIiMGI:1913507 Nicn1

Phylogenomic databases

eggNOGiENOG410IHPW Eukaryota
ENOG4111GDK LUCA
GeneTreeiENSGT00390000001505
HOGENOMiHOG000006705
HOVERGENiHBG052619
InParanoidiQ9CQM0
KOiK16607
OMAiCEQPAPL
OrthoDBiEOG091G0NXM
PhylomeDBiQ9CQM0
TreeFamiTF329753

Miscellaneous databases

PROiPR:Q9CQM0
SOURCEiSearch...

Gene expression databases

BgeeiENSMUSG00000032606 Expressed in 272 organ(s), highest expression level in ear
GenevisibleiQ9CQM0 MM

Family and domain databases

ProtoNetiSearch...

Entry informationi

Entry nameiNICN1_MOUSE
AccessioniPrimary (citable) accession number: Q9CQM0
Entry historyiIntegrated into UniProtKB/Swiss-Prot: August 31, 2004
Last sequence update: June 1, 2001
Last modified: November 7, 2018
This is version 86 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. MGD cross-references
    Mouse Genome Database (MGD) cross-references in UniProtKB/Swiss-Prot
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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