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Protein

MORF4 family-associated protein 1

Gene

Mrfap1

Organism
Mus musculus (Mouse)
Status
Reviewed-Annotation score: -Experimental evidence at protein leveli

Names & Taxonomyi

Protein namesi
Recommended name:
MORF4 family-associated protein 1
Alternative name(s):
Protein associated with MRG of 14 kDa
Gene namesi
Name:Mrfap1Imported
Synonyms:Pam14
ORF Names:MNCb-1039
OrganismiMus musculus (Mouse)
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeMusMus
Proteomesi
  • UP000000589 Componenti: Chromosome 5

Organism-specific databases

MGIiMGI:1914818 Mrfap1

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

Cytoplasm, Nucleus

Pathology & Biotechi

Disruption phenotypei

Male mice are viable, fertile and show normal T-cell function.1 Publication

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00003061771 – 125MORF4 family-associated protein 1Add BLAST125

Proteomic databases

EPDiQ9CQL7
MaxQBiQ9CQL7
PaxDbiQ9CQL7
PRIDEiQ9CQL7

PTM databases

iPTMnetiQ9CQL7
PhosphoSitePlusiQ9CQL7

Expressioni

Tissue specificityi

Widely expressed in all tissues examined and as early as 7 days during embryonic development.1 Publication

Gene expression databases

BgeeiENSMUSG00000055302 Expressed in 37 organ(s), highest expression level in Ammon's horn
CleanExiMM_MRFAP1
GenevisibleiQ9CQL7 MM

Interactioni

Subunit structurei

Found in a complex composed of MORF4L1, MRFAP1 and RB1. Interacts via its N-terminus with MORF4L1. Interacts with CSTB and MORF4L2.By similarity1 Publication

Protein-protein interaction databases

BioGridi212280, 1 interactor
IntActiQ9CQL7, 1 interactor
STRINGi10090.ENSMUSP00000067135

Family & Domainsi

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Coiled coili94 – 124Sequence analysisAdd BLAST31

Sequence similaritiesi

Keywords - Domaini

Coiled coil

Phylogenomic databases

eggNOGiENOG410J03M Eukaryota
ENOG4111AYE LUCA
GeneTreeiENSGT00510000046304
HOGENOMiHOG000070216
HOVERGENiHBG104090
InParanoidiQ9CQL7
OMAiRGTKRCE
OrthoDBiEOG091G10XY
PhylomeDBiQ9CQL7
TreeFamiTF338232

Family and domain databases

InterProiView protein in InterPro
IPR029254 MRFAP1
PANTHERiPTHR31324 PTHR31324, 1 hit
PfamiView protein in Pfam
PF15155 MRFAP1, 1 hit

Sequencei

Sequence statusi: Complete.

Q9CQL7-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MRPLDAVELA EPEEVEVLEP EEDFEQFLLP VIHEMREDIA SLTRERGRAP
60 70 80 90 100
ARNRGKLWEM DNMLIQIKTQ VEASEESALN HLQGAGGAEP RGPRAEKADE
110 120
KAQEMAKMAE MLVQLVRRIE KSESS
Length:125
Mass (Da):14,194
Last modified:June 1, 2001 - v1
Checksum:i7933E2FBCDAFF90E
GO

Sequence cautioni

The sequence BAB31978 differs from that shown. Reason: Frameshift at positions 115, 121 and 125.Curated

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AB041651 mRNA Translation: BAB93545.1
AK009827 mRNA Translation: BAB26527.1
AK017832 mRNA Translation: BAB30963.1
AK018675 mRNA Translation: BAB31337.1
AK020049 mRNA Translation: BAB31978.1 Frameshift.
AK159464 mRNA Translation: BAE35105.1
AK167112 mRNA Translation: BAE39260.1
AK170789 mRNA Translation: BAE42029.1
AK170909 mRNA Translation: BAE42107.1
AK170984 mRNA Translation: BAE42158.1
BC010209 mRNA Translation: AAH10209.1
CCDSiCCDS19242.1
RefSeqiNP_080518.1, NM_026242.3
UniGeneiMm.332336
Mm.490257

Genome annotation databases

EnsembliENSMUST00000068795; ENSMUSP00000067135; ENSMUSG00000055302
GeneIDi67568
KEGGimmu:67568
UCSCiuc008xfa.2 mouse

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AB041651 mRNA Translation: BAB93545.1
AK009827 mRNA Translation: BAB26527.1
AK017832 mRNA Translation: BAB30963.1
AK018675 mRNA Translation: BAB31337.1
AK020049 mRNA Translation: BAB31978.1 Frameshift.
AK159464 mRNA Translation: BAE35105.1
AK167112 mRNA Translation: BAE39260.1
AK170789 mRNA Translation: BAE42029.1
AK170909 mRNA Translation: BAE42107.1
AK170984 mRNA Translation: BAE42158.1
BC010209 mRNA Translation: AAH10209.1
CCDSiCCDS19242.1
RefSeqiNP_080518.1, NM_026242.3
UniGeneiMm.332336
Mm.490257

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi212280, 1 interactor
IntActiQ9CQL7, 1 interactor
STRINGi10090.ENSMUSP00000067135

PTM databases

iPTMnetiQ9CQL7
PhosphoSitePlusiQ9CQL7

Proteomic databases

EPDiQ9CQL7
MaxQBiQ9CQL7
PaxDbiQ9CQL7
PRIDEiQ9CQL7

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSMUST00000068795; ENSMUSP00000067135; ENSMUSG00000055302
GeneIDi67568
KEGGimmu:67568
UCSCiuc008xfa.2 mouse

Organism-specific databases

CTDi93621
MGIiMGI:1914818 Mrfap1

Phylogenomic databases

eggNOGiENOG410J03M Eukaryota
ENOG4111AYE LUCA
GeneTreeiENSGT00510000046304
HOGENOMiHOG000070216
HOVERGENiHBG104090
InParanoidiQ9CQL7
OMAiRGTKRCE
OrthoDBiEOG091G10XY
PhylomeDBiQ9CQL7
TreeFamiTF338232

Miscellaneous databases

PROiPR:Q9CQL7
SOURCEiSearch...

Gene expression databases

BgeeiENSMUSG00000055302 Expressed in 37 organ(s), highest expression level in Ammon's horn
CleanExiMM_MRFAP1
GenevisibleiQ9CQL7 MM

Family and domain databases

InterProiView protein in InterPro
IPR029254 MRFAP1
PANTHERiPTHR31324 PTHR31324, 1 hit
PfamiView protein in Pfam
PF15155 MRFAP1, 1 hit
ProtoNetiSearch...

Entry informationi

Entry nameiMOFA1_MOUSE
AccessioniPrimary (citable) accession number: Q9CQL7
Secondary accession number(s): Q9CX68
Entry historyiIntegrated into UniProtKB/Swiss-Prot: October 2, 2007
Last sequence update: June 1, 2001
Last modified: September 12, 2018
This is version 109 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families
  2. MGD cross-references
    Mouse Genome Database (MGD) cross-references in UniProtKB/Swiss-Prot
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Main funding by: National Institutes of Health

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