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UniProtKB - Q9CQL4 (RM20_MOUSE)

Entry version 146 (25 May 2022)
Sequence version 1 (01 Jun 2001)
Previous versions | rss
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Protein

39S ribosomal protein L20, mitochondrial

Gene

Mrpl20

Organism
Mus musculus (Mouse)
Status
Reviewed-Annotation score:

Annotation score:3 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

Complete GO annotation on QuickGO ...

GO - Biological processi

Complete GO annotation on QuickGO ...

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Molecular functionRibonucleoprotein, Ribosomal protein

Enzyme and pathway databases

Reactome - a knowledgebase of biological pathways and processes

More...Reactomei		R-MMU-5389840, Mitochondrial translation elongation
R-MMU-5419276, Mitochondrial translation termination

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
39S ribosomal protein L20, mitochondrial
Short name:
L20mt
Short name:
MRP-L20
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:Mrpl20
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiMus musculus (Mouse)
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri10090 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Glires › Rodentia › Myomorpha › Muroidea › Muridae › Murinae › Mus › Mus
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000000589 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 4

Organism-specific databases

Mouse genome database (MGD) from Mouse Genome Informatics (MGI)

More...MGIi		MGI:2137221, Mrpl20

Eukaryotic Pathogen, Vector and Host Database Resources

More...VEuPathDBi		HostDB:ENSMUSG00000029066

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Keywords - Cellular componenti

Mitochondrion

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'PTM / Processing' section describes the extent of a transit peptide.<p><a href='/help/transit' target='_top'>More...</a></p>Transit peptidei1 – 9MitochondrionBy similarity9
<p>This subsection of the 'PTM / Processing' section describes the extent of a polypeptide chain in the mature protein following processing or proteolytic cleavage.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_000024828010 – 14939S ribosomal protein L20, mitochondrialAdd BLAST140

Proteomic databases

Encyclopedia of Proteome Dynamics

More...EPDi		Q9CQL4

jPOST - Japan Proteome Standard Repository/Database

More...jPOSTi		Q9CQL4

MaxQB - The MaxQuant DataBase

More...MaxQBi		Q9CQL4

PaxDb, a database of protein abundance averages across all three domains of life

More...PaxDbi		Q9CQL4

PeptideAtlas

More...PeptideAtlasi		Q9CQL4

PRoteomics IDEntifications database

More...PRIDEi		Q9CQL4

ProteomicsDB: a multi-organism proteome resource

More...ProteomicsDBi		300519

PTM databases

iPTMnet integrated resource for PTMs in systems biology context

More...iPTMneti		Q9CQL4

Comprehensive resource for the study of protein post-translational modifications (PTMs) in human, mouse and rat.

More...PhosphoSitePlusi		Q9CQL4

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...Bgeei		ENSMUSG00000029066, Expressed in submandibular gland and 316 other tissues

ExpressionAtlas, Differential and Baseline Expression

More...ExpressionAtlasi		Q9CQL4, baseline and differential

Genevisible search portal to normalized and curated expression data from Genevestigator

More...Genevisiblei		Q9CQL4, MM

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

<p>This subsection of the <a href="http://www.uniprot.org/help/interaction%5Fsection">'Interaction'</a> section provides information about the protein quaternary structure and interaction(s) with other proteins or protein complexes (with the exception of physiological receptor-ligand interactions which are annotated in the <a href="http://www.uniprot.org/help/function%5Fsection">'Function'</a> section).<p><a href='/help/subunit_structure' target='_top'>More...</a></p>Subunit structurei

Component of the mitochondrial ribosome large subunit (39S) which comprises a 16S rRNA and about 50 distinct proteins (By similarity).

Interacts with OXA1L (By similarity).

By similarity

Protein-protein interaction databases

The Biological General Repository for Interaction Datasets (BioGRID)

More...BioGRIDi		211482, 2 interactors

ComplexPortal: manually curated resource of macromolecular complexes

More...ComplexPortali		CPX-5302, 39S mitochondrial large ribosomal subunit

STRING: functional protein association networks

More...STRINGi		10090.ENSMUSP00000030942

Miscellaneous databases

RNAct, Protein-RNA interaction predictions for model organisms.

More...RNActi		Q9CQL4, protein

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

AlphaFold Protein Structure Database

More...AlphaFoldDBi		Q9CQL4

SWISS-MODEL Repository - a database of annotated 3D protein structure models

More...SMRi		Q9CQL4

Database of comparative protein structure models

More...ModBasei		Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

<p>This subsection of the 'Family and domains' section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Belongs to the bacterial ribosomal protein bL20 family.Curated

Keywords - Domaini

Transit peptide

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...eggNOGi		KOG4707, Eukaryota

Ensembl GeneTree

More...GeneTreei		ENSGT00390000015823

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...HOGENOMi		CLU_123265_1_1_1

InParanoid: Eukaryotic Ortholog Groups

More...InParanoidi		Q9CQL4

Identification of Orthologs from Complete Genome Data

More...OMAi		GRRKNVW

Database of Orthologous Groups

More...OrthoDBi		1582185at2759

Database for complete collections of gene phylogenies

More...PhylomeDBi		Q9CQL4

TreeFam database of animal gene trees

More...TreeFami		TF324702

Family and domain databases

Conserved Domains Database

More...CDDi		cd07026, Ribosomal_L20, 1 hit

Gene3D Structural and Functional Annotation of Protein Families

More...Gene3Di		1.10.1900.20, 1 hit

Integrated resource of protein families, domains and functional sites

More...InterProi		View protein in InterPro
IPR005813, Ribosomal_L20
IPR035566, Ribosomal_protein_L20_C

The PANTHER Classification System

More...PANTHERi		PTHR10986, PTHR10986, 1 hit

Pfam protein domain database

More...Pfami		View protein in Pfam
PF00453, Ribosomal_L20, 1 hit

Protein Motif fingerprint database; a protein domain database

More...PRINTSi		PR00062, RIBOSOMALL20

Superfamily database of structural and functional annotation

More...SUPFAMi		SSF74731, SSF74731, 1 hit

TIGRFAMs; a protein family database

More...TIGRFAMsi		TIGR01032, rplT_bact, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequence (1+)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is in its mature form or if it represents the precursor.<p><a href='/help/sequence_processing' target='_top'>More...</a></p>Sequence processingi: The displayed sequence is further processed into a mature form.

This entry has 1 described isoform and 2 potential isoforms that are computationally mapped.Show allAlign All

Q9CQL4-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MVFLTTRLWL RNRLTDRYWR VQEVLKHAQH FRGRKNRCYR LAVRAVTRAF 
        60         70         80         90        100
VKCTKARRLK KRNLRTLWIN RITAASQEHG LKYPAFIVNL IKCQVELNRK 
       110        120        130        140 
VLVDLAIYEP KTFKSLAALA KRRQQEGFAA ALGDGKEPEG IFSRVVQYH
Length:149
Mass (Da):17,595
Last modified:June 1, 2001 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i7B86D8C568B633AE
GO

<p>In eukaryotic reference proteomes, unreviewed entries that are likely to belong to the same gene are computationally mapped, based on gene identifiers from Ensembl, EnsemblGenomes and model organism databases.<p><a href='/help/gene_centric_isoform_mapping' target='_top'>More...</a></p>Computationally mapped potential isoform sequencesi

There are 2 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
V9GX65V9GX65_MOUSE
39S ribosomal protein L20, mitochon...
Mrpl20
96Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
V9GXI7V9GXI7_MOUSE
39S ribosomal protein L20, mitochon...
Mrpl20
112Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Sequence' section reports difference(s) between the canonical sequence (displayed by default in the entry) and the different sequence submissions merged in the entry. These various submissions may originate from different sequencing projects, different types of experiments, or different biological samples. Sequence conflicts are usually of unknown origin.<p><a href='/help/conflict' target='_top'>More...</a></p>Sequence conflicti62R → L in BAB29744 (PubMed:16141072).Curated1

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...EMBLi

GenBank nucleotide sequence database

More...GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...DDBJi
Links Updated
AB049645 mRNA Translation: BAB40850.1
AK004053 mRNA Translation: BAB23143.1
AK011341 mRNA Translation: BAB27555.1
AK015199 mRNA Translation: BAB29744.1
AK168665 mRNA Translation: BAE40517.1
BC039985 mRNA Translation: AAH39985.1

The Consensus CDS (CCDS) project

More...CCDSi		CCDS19041.1

NCBI Reference Sequences

More...RefSeqi		NP_079846.1, NM_025570.2
XP_006539167.1, XM_006539104.2

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...Ensembli		ENSMUST00000030942; ENSMUSP00000030942; ENSMUSG00000029066
ENSMUST00000137487; ENSMUSP00000139122; ENSMUSG00000029066

Database of genes from NCBI RefSeq genomes

More...GeneIDi		66448

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...KEGGi		mmu:66448

UCSC genome browser

More...UCSCi		uc008weu.1, mouse

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AB049645 mRNA Translation: BAB40850.1
AK004053 mRNA Translation: BAB23143.1
AK011341 mRNA Translation: BAB27555.1
AK015199 mRNA Translation: BAB29744.1
AK168665 mRNA Translation: BAE40517.1
BC039985 mRNA Translation: AAH39985.1
CCDSiCCDS19041.1
RefSeqiNP_079846.1, NM_025570.2
XP_006539167.1, XM_006539104.2

3D structure databases

AlphaFoldDBiQ9CQL4
SMRiQ9CQL4
ModBaseiSearch...

Protein-protein interaction databases

BioGRIDi211482, 2 interactors
ComplexPortaliCPX-5302, 39S mitochondrial large ribosomal subunit
STRINGi10090.ENSMUSP00000030942

PTM databases

iPTMnetiQ9CQL4
PhosphoSitePlusiQ9CQL4

Proteomic databases

EPDiQ9CQL4
jPOSTiQ9CQL4
MaxQBiQ9CQL4
PaxDbiQ9CQL4
PeptideAtlasiQ9CQL4
PRIDEiQ9CQL4
ProteomicsDBi300519

Protocols and materials databases

Antibodypedia a portal for validated antibodies

More...Antibodypediai		51971, 93 antibodies from 18 providers

The DNASU plasmid repository

More...DNASUi		66448

Genome annotation databases

EnsembliENSMUST00000030942; ENSMUSP00000030942; ENSMUSG00000029066
ENSMUST00000137487; ENSMUSP00000139122; ENSMUSG00000029066
GeneIDi66448
KEGGimmu:66448
UCSCiuc008weu.1, mouse

Organism-specific databases

Comparative Toxicogenomics Database

More...CTDi		55052
MGIiMGI:2137221, Mrpl20
VEuPathDBiHostDB:ENSMUSG00000029066

Phylogenomic databases

eggNOGiKOG4707, Eukaryota
GeneTreeiENSGT00390000015823
HOGENOMiCLU_123265_1_1_1
InParanoidiQ9CQL4
OMAiGRRKNVW
OrthoDBi1582185at2759
PhylomeDBiQ9CQL4
TreeFamiTF324702

Enzyme and pathway databases

ReactomeiR-MMU-5389840, Mitochondrial translation elongation
R-MMU-5419276, Mitochondrial translation termination

Miscellaneous databases

BioGRID ORCS database of CRISPR phenotype screens

More...BioGRID-ORCSi		66448, 30 hits in 73 CRISPR screens

ChiTaRS: a database of human, mouse and fruit fly chimeric transcripts and RNA-sequencing data

More...ChiTaRSi		Mrpl20, mouse

Protein Ontology

More...PROi		PR:Q9CQL4
RNActiQ9CQL4, protein

The Stanford Online Universal Resource for Clones and ESTs

More...SOURCEi		Search...

Gene expression databases

BgeeiENSMUSG00000029066, Expressed in submandibular gland and 316 other tissues
ExpressionAtlasiQ9CQL4, baseline and differential
GenevisibleiQ9CQL4, MM

Family and domain databases

CDDicd07026, Ribosomal_L20, 1 hit
Gene3Di1.10.1900.20, 1 hit
InterProiView protein in InterPro
IPR005813, Ribosomal_L20
IPR035566, Ribosomal_protein_L20_C
PANTHERiPTHR10986, PTHR10986, 1 hit
PfamiView protein in Pfam
PF00453, Ribosomal_L20, 1 hit
PRINTSiPR00062, RIBOSOMALL20
SUPFAMiSSF74731, SSF74731, 1 hit
TIGRFAMsiTIGR01032, rplT_bact, 1 hit

MobiDB: a database of protein disorder and mobility annotations

More...MobiDBi		Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiRM20_MOUSE
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q9CQL4
Secondary accession number(s): Q9D5L3
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: September 5, 2006
Last sequence update: June 1, 2001
Last modified: May 25, 2022
This is version 146 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Direct protein sequencing, Reference proteome

Documents

  1. Ribosomal proteins
    Ribosomal proteins families and list of entries
  2. MGD cross-references
    Mouse Genome Database (MGD) cross-references in UniProtKB/Swiss-Prot
  3. SIMILARITY comments
    Index of protein domains and families
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