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UniProtKB - Q9CQL4 (RM20_MOUSE)
Protein
39S ribosomal protein L20, mitochondrial
Gene
Mrpl20
Organism
Mus musculus (Mouse)
Status
Functioni
GO - Molecular functioni
- rRNA binding Source: InterPro
- structural constituent of ribosome Source: MGI
GO - Biological processi
- mitochondrial translation Source: ComplexPortal
- ribosomal large subunit assembly Source: GO_Central
- translation Source: MGI
Keywordsi
Molecular function | Ribonucleoprotein, Ribosomal protein |
Enzyme and pathway databases
Reactomei | R-MMU-5389840, Mitochondrial translation elongation R-MMU-5419276, Mitochondrial translation termination |
Names & Taxonomyi
Protein namesi | Recommended name: 39S ribosomal protein L20, mitochondrialShort name: L20mt Short name: MRP-L20 |
Gene namesi | Name:Mrpl20 |
Organismi | Mus musculus (Mouse) |
Taxonomic identifieri | 10090 [NCBI] |
Taxonomic lineagei | Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Glires › Rodentia › Myomorpha › Muroidea › Muridae › Murinae › Mus › Mus |
Proteomesi |
|
Organism-specific databases
MGIi | MGI:2137221, Mrpl20 |
VEuPathDBi | HostDB:ENSMUSG00000029066 |
Subcellular locationi
Mitochondrion
- Mitochondrion By similarity
Mitochondrion
- mitochondrial inner membrane Source: ComplexPortal
- mitochondrial large ribosomal subunit Source: UniProtKB
- mitochondrial ribosome Source: UniProtKB
- mitochondrion Source: MGI
Keywords - Cellular componenti
MitochondrionPTM / Processingi
Molecule processing
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Transit peptidei | 1 – 9 | MitochondrionBy similarity | 9 | |
ChainiPRO_0000248280 | 10 – 149 | 39S ribosomal protein L20, mitochondrialAdd BLAST | 140 |
Proteomic databases
EPDi | Q9CQL4 |
jPOSTi | Q9CQL4 |
MaxQBi | Q9CQL4 |
PaxDbi | Q9CQL4 |
PeptideAtlasi | Q9CQL4 |
PRIDEi | Q9CQL4 |
ProteomicsDBi | 300519 |
PTM databases
iPTMneti | Q9CQL4 |
PhosphoSitePlusi | Q9CQL4 |
Expressioni
Gene expression databases
Bgeei | ENSMUSG00000029066, Expressed in submandibular gland and 316 other tissues |
ExpressionAtlasi | Q9CQL4, baseline and differential |
Genevisiblei | Q9CQL4, MM |
Interactioni
Subunit structurei
Component of the mitochondrial ribosome large subunit (39S) which comprises a 16S rRNA and about 50 distinct proteins (By similarity).
Interacts with OXA1L (By similarity).
By similarityProtein-protein interaction databases
BioGRIDi | 211482, 2 interactors |
ComplexPortali | CPX-5302, 39S mitochondrial large ribosomal subunit |
STRINGi | 10090.ENSMUSP00000030942 |
Miscellaneous databases
RNActi | Q9CQL4, protein |
Family & Domainsi
Sequence similaritiesi
Belongs to the bacterial ribosomal protein bL20 family.Curated
Keywords - Domaini
Transit peptidePhylogenomic databases
eggNOGi | KOG4707, Eukaryota |
GeneTreei | ENSGT00390000015823 |
HOGENOMi | CLU_123265_1_1_1 |
InParanoidi | Q9CQL4 |
OMAi | GRRKNVW |
OrthoDBi | 1582185at2759 |
PhylomeDBi | Q9CQL4 |
TreeFami | TF324702 |
Family and domain databases
CDDi | cd07026, Ribosomal_L20, 1 hit |
Gene3Di | 1.10.1900.20, 1 hit |
InterProi | View protein in InterPro IPR005813, Ribosomal_L20 IPR035566, Ribosomal_protein_L20_C |
PANTHERi | PTHR10986, PTHR10986, 1 hit |
Pfami | View protein in Pfam PF00453, Ribosomal_L20, 1 hit |
PRINTSi | PR00062, RIBOSOMALL20 |
SUPFAMi | SSF74731, SSF74731, 1 hit |
TIGRFAMsi | TIGR01032, rplT_bact, 1 hit |
(1+)i Sequence
Sequence statusi: Complete.
: The displayed sequence is further processed into a mature form. Sequence processingi
This entry has 1 described isoform and 2 potential isoforms that are computationally mapped.Show allAlign All
Q9CQL4-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MVFLTTRLWL RNRLTDRYWR VQEVLKHAQH FRGRKNRCYR LAVRAVTRAF
60 70 80 90 100
VKCTKARRLK KRNLRTLWIN RITAASQEHG LKYPAFIVNL IKCQVELNRK
110 120 130 140
VLVDLAIYEP KTFKSLAALA KRRQQEGFAA ALGDGKEPEG IFSRVVQYH
Computationally mapped potential isoform sequencesi
There are 2 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basketV9GX65 | V9GX65_MOUSE | 39S ribosomal protein L20, mitochon... | Mrpl20 | 96 | Annotation score: | ||
V9GXI7 | V9GXI7_MOUSE | 39S ribosomal protein L20, mitochon... | Mrpl20 | 112 | Annotation score: |
Experimental Info
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Sequence conflicti | 62 | R → L in BAB29744 (PubMed:16141072).Curated | 1 |
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AB049645 mRNA Translation: BAB40850.1 AK004053 mRNA Translation: BAB23143.1 AK011341 mRNA Translation: BAB27555.1 AK015199 mRNA Translation: BAB29744.1 AK168665 mRNA Translation: BAE40517.1 BC039985 mRNA Translation: AAH39985.1 |
CCDSi | CCDS19041.1 |
RefSeqi | NP_079846.1, NM_025570.2 XP_006539167.1, XM_006539104.2 |
Genome annotation databases
Ensembli | ENSMUST00000030942; ENSMUSP00000030942; ENSMUSG00000029066 ENSMUST00000137487; ENSMUSP00000139122; ENSMUSG00000029066 |
GeneIDi | 66448 |
KEGGi | mmu:66448 |
UCSCi | uc008weu.1, mouse |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AB049645 mRNA Translation: BAB40850.1 AK004053 mRNA Translation: BAB23143.1 AK011341 mRNA Translation: BAB27555.1 AK015199 mRNA Translation: BAB29744.1 AK168665 mRNA Translation: BAE40517.1 BC039985 mRNA Translation: AAH39985.1 |
CCDSi | CCDS19041.1 |
RefSeqi | NP_079846.1, NM_025570.2 XP_006539167.1, XM_006539104.2 |
3D structure databases
AlphaFoldDBi | Q9CQL4 |
SMRi | Q9CQL4 |
ModBasei | Search... |
Protein-protein interaction databases
BioGRIDi | 211482, 2 interactors |
ComplexPortali | CPX-5302, 39S mitochondrial large ribosomal subunit |
STRINGi | 10090.ENSMUSP00000030942 |
PTM databases
iPTMneti | Q9CQL4 |
PhosphoSitePlusi | Q9CQL4 |
Proteomic databases
EPDi | Q9CQL4 |
jPOSTi | Q9CQL4 |
MaxQBi | Q9CQL4 |
PaxDbi | Q9CQL4 |
PeptideAtlasi | Q9CQL4 |
PRIDEi | Q9CQL4 |
ProteomicsDBi | 300519 |
Protocols and materials databases
Antibodypediai | 51971, 93 antibodies from 18 providers |
DNASUi | 66448 |
Genome annotation databases
Ensembli | ENSMUST00000030942; ENSMUSP00000030942; ENSMUSG00000029066 ENSMUST00000137487; ENSMUSP00000139122; ENSMUSG00000029066 |
GeneIDi | 66448 |
KEGGi | mmu:66448 |
UCSCi | uc008weu.1, mouse |
Organism-specific databases
CTDi | 55052 |
MGIi | MGI:2137221, Mrpl20 |
VEuPathDBi | HostDB:ENSMUSG00000029066 |
Phylogenomic databases
eggNOGi | KOG4707, Eukaryota |
GeneTreei | ENSGT00390000015823 |
HOGENOMi | CLU_123265_1_1_1 |
InParanoidi | Q9CQL4 |
OMAi | GRRKNVW |
OrthoDBi | 1582185at2759 |
PhylomeDBi | Q9CQL4 |
TreeFami | TF324702 |
Enzyme and pathway databases
Reactomei | R-MMU-5389840, Mitochondrial translation elongation R-MMU-5419276, Mitochondrial translation termination |
Miscellaneous databases
BioGRID-ORCSi | 66448, 30 hits in 73 CRISPR screens |
ChiTaRSi | Mrpl20, mouse |
PROi | PR:Q9CQL4 |
RNActi | Q9CQL4, protein |
SOURCEi | Search... |
Gene expression databases
Bgeei | ENSMUSG00000029066, Expressed in submandibular gland and 316 other tissues |
ExpressionAtlasi | Q9CQL4, baseline and differential |
Genevisiblei | Q9CQL4, MM |
Family and domain databases
CDDi | cd07026, Ribosomal_L20, 1 hit |
Gene3Di | 1.10.1900.20, 1 hit |
InterProi | View protein in InterPro IPR005813, Ribosomal_L20 IPR035566, Ribosomal_protein_L20_C |
PANTHERi | PTHR10986, PTHR10986, 1 hit |
Pfami | View protein in Pfam PF00453, Ribosomal_L20, 1 hit |
PRINTSi | PR00062, RIBOSOMALL20 |
SUPFAMi | SSF74731, SSF74731, 1 hit |
TIGRFAMsi | TIGR01032, rplT_bact, 1 hit |
MobiDBi | Search... |
Entry informationi
Entry namei | RM20_MOUSE | |
Accessioni | Q9CQL4Primary (citable) accession number: Q9CQL4 Secondary accession number(s): Q9D5L3 | |
Entry historyi | Integrated into UniProtKB/Swiss-Prot: | September 5, 2006 |
Last sequence update: | June 1, 2001 | |
Last modified: | May 25, 2022 | |
This is version 146 of the entry and version 1 of the sequence. See complete history. | ||
Entry statusi | Reviewed (UniProtKB/Swiss-Prot) | |
Annotation program | Chordata Protein Annotation Program |
Miscellaneousi
Keywords - Technical termi
Direct protein sequencing, Reference proteomeDocuments
- Ribosomal proteins
Ribosomal proteins families and list of entries - MGD cross-references
Mouse Genome Database (MGD) cross-references in UniProtKB/Swiss-Prot - SIMILARITY comments
Index of protein domains and families