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UniProtKB - Q9CQG8 (Q9CQG8_MOUSE)
Protein
Protein kinase domain-containing protein
Gene
Lrrk2
Organism
Mus musculus (Mouse)
Status
Functioni
GO - Molecular functioni
- ATP binding Source: InterPro
- protein kinase activity Source: InterPro
GO - Biological processi
- cellular response to stress Source: UniProt
Names & Taxonomyi
Protein namesi | Recommended name: Protein kinase domain-containing proteinInterPro annotation |
Gene namesi | Name:Lrrk2Imported |
Organismi | Mus musculus (Mouse)Imported |
Taxonomic identifieri | 10090 [NCBI] |
Taxonomic lineagei | Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Glires › Rodentia › Myomorpha › Muroidea › Muridae › Murinae › Mus › Mus |
Organism-specific databases
MGIi | MGI:1913975, Lrrk2 |
Subcellular locationi
Endosome
- endosome Source: UniProtKB-KW
Keywords - Cellular componenti
EndosomeARBA annotationStructurei
Family & Domainsi
Domains and Repeats
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Domaini | 1 – 180 | Protein kinaseInterPro annotationAdd BLAST | 180 |
Phylogenomic databases
OrthoDBi | 14978at2759 |
Family and domain databases
Gene3Di | 2.130.10.10, 2 hits |
InterProi | View protein in InterPro IPR011009, Kinase-like_dom_sf IPR000719, Prot_kinase_dom IPR008271, Ser/Thr_kinase_AS IPR015943, WD40/YVTN_repeat-like_dom_sf IPR036322, WD40_repeat_dom_sf |
Pfami | View protein in Pfam PF00069, Pkinase, 1 hit |
SMARTi | View protein in SMART SM00220, S_TKc, 1 hit |
SUPFAMi | SSF50978, SSF50978, 1 hit SSF56112, SSF56112, 1 hit |
PROSITEi | View protein in PROSITE PS50011, PROTEIN_KINASE_DOM, 1 hit PS00108, PROTEIN_KINASE_ST, 1 hit |
i Sequence
Sequence statusi: Complete.
Q9CQG8-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MLGAIFERPI PPDTRPWYLH SAMIIYRDLK PHNVLLFTLY PNAAIIAKIA
60 70 80 90 100
DYGIAQYCCR MGIKTSEGTP GFRAPEVARG NVIYNQQADV YSFGLLLHDI
110 120 130 140 150
WTTGSRIMEG LRFPNEFDEL AIQGKLPDPV KEYGCAPWPM VEKLITKCLK
160 170 180 190 200
ENPQERPTSA QVFDILNSAE LICLMRHILI PKNIIVECMV ATNLNSKSAT
210 220 230 240 250
LWLGCGNTEK GQLSLFDLNT ERYSYEEVAD SRILCLALVH LAAEKESWVV
260 270 280 290 300
CGTQSGALLV INVEEETKRH TLEKMTDSVT CLHCNSLAKQ SKQSNFLLVG
310 320 330 340 350
TADGNLMIFE DKAVKCKGAA PLKTLHIGDV STPLMCLSES LNSSERHITW
360 370 380 390 400
GGCGTKVFSF SNDFTIQKLI ETKTNQLFSY AAFSDSNIIA LAVDTALYIA
410 420 430 440 450
KKNSPVVEVW DKKTEKLCEL IDCVHFLKEV MVKLNKESKH QLSYSGRVKA
460 470 480 490 500
LCLQKNTALW IGTGGGHILL LDLSTRRVIR TIHNFCDSVR AMATAQLGSL
510 520 530 540 550
KNVMLVLGYK RKSTEGIQEQ KEIQSCLSIW DLNLPHEVQN LEKHIEVRTE
560
LADKMRKTSV E
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AK014886 mRNA Translation: BAB29603.1 AK014938 mRNA Translation: BAB29628.1 |
RefSeqi | NP_080006.3, NM_025730.3 |
Genome annotation databases
GeneIDi | 66725 |
KEGGi | mmu:66725 |
UCSCi | uc007xia.1, mouse |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AK014886 mRNA Translation: BAB29603.1 AK014938 mRNA Translation: BAB29628.1 |
RefSeqi | NP_080006.3, NM_025730.3 |
3D structure databases
ModBasei | Search... |
SWISS-MODEL-Workspacei | Submit a new modelling project... |
Protocols and materials databases
DNASUi | 66725 |
Genome annotation databases
GeneIDi | 66725 |
KEGGi | mmu:66725 |
UCSCi | uc007xia.1, mouse |
Organism-specific databases
CTDi | 120892 |
MGIi | MGI:1913975, Lrrk2 |
Phylogenomic databases
OrthoDBi | 14978at2759 |
Miscellaneous databases
BioGRID-ORCSi | 66725, 3 hits in 65 CRISPR screens |
ChiTaRSi | Lrrk2, mouse |
SOURCEi | Search... |
Family and domain databases
Gene3Di | 2.130.10.10, 2 hits |
InterProi | View protein in InterPro IPR011009, Kinase-like_dom_sf IPR000719, Prot_kinase_dom IPR008271, Ser/Thr_kinase_AS IPR015943, WD40/YVTN_repeat-like_dom_sf IPR036322, WD40_repeat_dom_sf |
Pfami | View protein in Pfam PF00069, Pkinase, 1 hit |
SMARTi | View protein in SMART SM00220, S_TKc, 1 hit |
SUPFAMi | SSF50978, SSF50978, 1 hit SSF56112, SSF56112, 1 hit |
PROSITEi | View protein in PROSITE PS50011, PROTEIN_KINASE_DOM, 1 hit PS00108, PROTEIN_KINASE_ST, 1 hit |
MobiDBi | Search... |
Entry informationi
Entry namei | Q9CQG8_MOUSE | |
Accessioni | Q9CQG8Primary (citable) accession number: Q9CQG8 | |
Entry historyi | Integrated into UniProtKB/TrEMBL: | June 1, 2001 |
Last sequence update: | June 1, 2001 | |
Last modified: | January 19, 2022 | |
This is version 141 of the entry and version 1 of the sequence. See complete history. | ||
Entry statusi | Unreviewed (UniProtKB/TrEMBL) |