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UniProtKB - Q9CQF0 (RM11_MOUSE)
Protein
39S ribosomal protein L11, mitochondrial
Gene
Mrpl11
Organism
Mus musculus (Mouse)
Status
Functioni
GO - Molecular functioni
- large ribosomal subunit rRNA binding Source: GO_Central
- structural constituent of ribosome Source: MGI
GO - Biological processi
- translation Source: MGI
Keywordsi
Molecular function | Ribonucleoprotein, Ribosomal protein |
Enzyme and pathway databases
Reactomei | R-MMU-5389840, Mitochondrial translation elongation R-MMU-5419276, Mitochondrial translation termination |
Names & Taxonomyi
Protein namesi | Recommended name: 39S ribosomal protein L11, mitochondrialShort name: L11mt Short name: MRP-L11 |
Gene namesi | Name:Mrpl11 |
Organismi | Mus musculus (Mouse) |
Taxonomic identifieri | 10090 [NCBI] |
Taxonomic lineagei | Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Glires › Rodentia › Myomorpha › Muroidea › Muridae › Murinae › Mus › Mus |
Proteomesi |
|
Organism-specific databases
MGIi | MGI:2137215, Mrpl11 |
VEuPathDBi | HostDB:ENSMUSG00000024902 |
Subcellular locationi
Mitochondrion
- Mitochondrion 1 Publication
Mitochondrion
- mitochondrial large ribosomal subunit Source: UniProtKB
- mitochondrion Source: MGI
Other locations
- large ribosomal subunit Source: GO_Central
Keywords - Cellular componenti
MitochondrionPTM / Processingi
Molecule processing
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Transit peptidei | 1 – ? | MitochondrionSequence analysis | ||
ChainiPRO_0000030444 | ? – 192 | 39S ribosomal protein L11, mitochondrial |
Proteomic databases
EPDi | Q9CQF0 |
MaxQBi | Q9CQF0 |
PaxDbi | Q9CQF0 |
PeptideAtlasi | Q9CQF0 |
PRIDEi | Q9CQF0 |
ProteomicsDBi | 300518 |
PTM databases
iPTMneti | Q9CQF0 |
PhosphoSitePlusi | Q9CQF0 |
Expressioni
Gene expression databases
Bgeei | ENSMUSG00000024902, Expressed in optic fissure and 308 other tissues |
ExpressionAtlasi | Q9CQF0, baseline and differential |
Genevisiblei | Q9CQF0, MM |
Interactioni
Subunit structurei
Component of the mitochondrial ribosome large subunit (39S) which comprises a 16S rRNA and about 50 distinct proteins.
By similarityProtein-protein interaction databases
BioGRIDi | 211460, 38 interactors |
ComplexPortali | CPX-5302, 39S mitochondrial large ribosomal subunit |
STRINGi | 10090.ENSMUSP00000025836 |
Miscellaneous databases
RNActi | Q9CQF0, protein |
Family & Domainsi
Sequence similaritiesi
Belongs to the universal ribosomal protein uL11 family.Curated
Keywords - Domaini
Transit peptidePhylogenomic databases
eggNOGi | KOG3257, Eukaryota |
GeneTreei | ENSGT00390000003153 |
HOGENOMi | CLU_074237_1_1_1 |
InParanoidi | Q9CQF0 |
OMAi | CKQFNAK |
OrthoDBi | 1346532at2759 |
PhylomeDBi | Q9CQF0 |
TreeFami | TF313471 |
Family and domain databases
CDDi | cd00349, Ribosomal_L11, 1 hit |
Gene3Di | 1.10.10.250, 1 hit 3.30.1550.10, 1 hit |
HAMAPi | MF_00736, Ribosomal_L11, 1 hit |
InterProi | View protein in InterPro IPR000911, Ribosomal_L11/L12 IPR036796, Ribosomal_L11/L12_N_sf IPR006519, Ribosomal_L11_bac-typ IPR020783, Ribosomal_L11_C IPR036769, Ribosomal_L11_C_sf IPR020784, Ribosomal_L11_N |
PANTHERi | PTHR11661, PTHR11661, 1 hit |
Pfami | View protein in Pfam PF00298, Ribosomal_L11, 1 hit PF03946, Ribosomal_L11_N, 1 hit |
SMARTi | View protein in SMART SM00649, RL11, 1 hit |
SUPFAMi | SSF46906, SSF46906, 1 hit SSF54747, SSF54747, 1 hit |
TIGRFAMsi | TIGR01632, L11_bact, 1 hit |
(1+)i Sequence
Sequence statusi: Complete.
: The displayed sequence is further processed into a mature form. Sequence processingi
This entry has 1 described isoform and 3 potential isoforms that are computationally mapped.Show allAlign All
Q9CQF0-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MSKLSRATRT LKKPEAGGVI RSIVRAGQAI PGPPLGPILG QRGVSINQFC
60 70 80 90 100
KEFNEKTKDI KEGIPLPTKI FIKPDRTFEL KIGQPTVSYF LKAAAGIEKG
110 120 130 140 150
ARHTGKEVAG LVSLKHVYEI ACVKAKDDAF AMQDVPLSSV VRSIIGSARS
160 170 180 190
LGIRVVKDLS AEELEAFQKE RAVFLAAQKE ADLAAQAEAA KK
Computationally mapped potential isoform sequencesi
There are 3 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basketA0A494B9R3 | A0A494B9R3_MOUSE | 39S ribosomal protein L11, mitochon... | Mrpl11 | 158 | Annotation score: | ||
A0A494B9H5 | A0A494B9H5_MOUSE | 39S ribosomal protein L11, mitochon... | Mrpl11 | 150 | Annotation score: | ||
A0A494B915 | A0A494B915_MOUSE | 39S ribosomal protein L11, mitochon... | Mrpl11 | 114 | Annotation score: |
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AB049639 mRNA Translation: BAB40844.1 AK002797 mRNA Translation: BAB22366.1 AK010329 mRNA Translation: BAB26856.1 AK167247 mRNA Translation: BAE39368.1 BC046750 mRNA Translation: AAH46750.1 |
CCDSi | CCDS29444.1 |
RefSeqi | NP_079829.1, NM_025553.4 |
Genome annotation databases
Ensembli | ENSMUST00000025836; ENSMUSP00000025836; ENSMUSG00000024902 |
GeneIDi | 66419 |
KEGGi | mmu:66419 |
UCSCi | uc008gbt.2, mouse |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AB049639 mRNA Translation: BAB40844.1 AK002797 mRNA Translation: BAB22366.1 AK010329 mRNA Translation: BAB26856.1 AK167247 mRNA Translation: BAE39368.1 BC046750 mRNA Translation: AAH46750.1 |
CCDSi | CCDS29444.1 |
RefSeqi | NP_079829.1, NM_025553.4 |
3D structure databases
SMRi | Q9CQF0 |
ModBasei | Search... |
Protein-protein interaction databases
BioGRIDi | 211460, 38 interactors |
ComplexPortali | CPX-5302, 39S mitochondrial large ribosomal subunit |
STRINGi | 10090.ENSMUSP00000025836 |
PTM databases
iPTMneti | Q9CQF0 |
PhosphoSitePlusi | Q9CQF0 |
Proteomic databases
EPDi | Q9CQF0 |
MaxQBi | Q9CQF0 |
PaxDbi | Q9CQF0 |
PeptideAtlasi | Q9CQF0 |
PRIDEi | Q9CQF0 |
ProteomicsDBi | 300518 |
Protocols and materials databases
Antibodypediai | 30159, 312 antibodies from 30 providers |
DNASUi | 66419 |
Genome annotation databases
Ensembli | ENSMUST00000025836; ENSMUSP00000025836; ENSMUSG00000024902 |
GeneIDi | 66419 |
KEGGi | mmu:66419 |
UCSCi | uc008gbt.2, mouse |
Organism-specific databases
CTDi | 65003 |
MGIi | MGI:2137215, Mrpl11 |
VEuPathDBi | HostDB:ENSMUSG00000024902 |
Phylogenomic databases
eggNOGi | KOG3257, Eukaryota |
GeneTreei | ENSGT00390000003153 |
HOGENOMi | CLU_074237_1_1_1 |
InParanoidi | Q9CQF0 |
OMAi | CKQFNAK |
OrthoDBi | 1346532at2759 |
PhylomeDBi | Q9CQF0 |
TreeFami | TF313471 |
Enzyme and pathway databases
Reactomei | R-MMU-5389840, Mitochondrial translation elongation R-MMU-5419276, Mitochondrial translation termination |
Miscellaneous databases
BioGRID-ORCSi | 66419, 18 hits in 64 CRISPR screens |
ChiTaRSi | Mrpl11, mouse |
PROi | PR:Q9CQF0 |
RNActi | Q9CQF0, protein |
SOURCEi | Search... |
Gene expression databases
Bgeei | ENSMUSG00000024902, Expressed in optic fissure and 308 other tissues |
ExpressionAtlasi | Q9CQF0, baseline and differential |
Genevisiblei | Q9CQF0, MM |
Family and domain databases
CDDi | cd00349, Ribosomal_L11, 1 hit |
Gene3Di | 1.10.10.250, 1 hit 3.30.1550.10, 1 hit |
HAMAPi | MF_00736, Ribosomal_L11, 1 hit |
InterProi | View protein in InterPro IPR000911, Ribosomal_L11/L12 IPR036796, Ribosomal_L11/L12_N_sf IPR006519, Ribosomal_L11_bac-typ IPR020783, Ribosomal_L11_C IPR036769, Ribosomal_L11_C_sf IPR020784, Ribosomal_L11_N |
PANTHERi | PTHR11661, PTHR11661, 1 hit |
Pfami | View protein in Pfam PF00298, Ribosomal_L11, 1 hit PF03946, Ribosomal_L11_N, 1 hit |
SMARTi | View protein in SMART SM00649, RL11, 1 hit |
SUPFAMi | SSF46906, SSF46906, 1 hit SSF54747, SSF54747, 1 hit |
TIGRFAMsi | TIGR01632, L11_bact, 1 hit |
MobiDBi | Search... |
Entry informationi
Entry namei | RM11_MOUSE | |
Accessioni | Q9CQF0Primary (citable) accession number: Q9CQF0 Secondary accession number(s): Q3TJX7 | |
Entry historyi | Integrated into UniProtKB/Swiss-Prot: | July 26, 2002 |
Last sequence update: | June 1, 2001 | |
Last modified: | February 23, 2022 | |
This is version 149 of the entry and version 1 of the sequence. See complete history. | ||
Entry statusi | Reviewed (UniProtKB/Swiss-Prot) | |
Annotation program | Chordata Protein Annotation Program |
Miscellaneousi
Keywords - Technical termi
Reference proteomeDocuments
- Ribosomal proteins
Ribosomal proteins families and list of entries - MGD cross-references
Mouse Genome Database (MGD) cross-references in UniProtKB/Swiss-Prot - SIMILARITY comments
Index of protein domains and families