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UniProtKB - Q9CQF0 (RM11_MOUSE)

Entry version 149 (23 Feb 2022)
Sequence version 1 (01 Jun 2001)
Previous versions | rss
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Protein

39S ribosomal protein L11, mitochondrial

Gene

Mrpl11

Organism
Mus musculus (Mouse)
Status
Reviewed-Annotation score:

Annotation score:2 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

Complete GO annotation on QuickGO ...

GO - Biological processi

Complete GO annotation on QuickGO ...

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Molecular functionRibonucleoprotein, Ribosomal protein

Enzyme and pathway databases

Reactome - a knowledgebase of biological pathways and processes

More...Reactomei		R-MMU-5389840, Mitochondrial translation elongation
R-MMU-5419276, Mitochondrial translation termination

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
39S ribosomal protein L11, mitochondrial
Short name:
L11mt
Short name:
MRP-L11
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:Mrpl11
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiMus musculus (Mouse)
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri10090 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Glires › Rodentia › Myomorpha › Muroidea › Muridae › Murinae › Mus › Mus
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000000589 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 19

Organism-specific databases

Mouse genome database (MGD) from Mouse Genome Informatics (MGI)

More...MGIi		MGI:2137215, Mrpl11

Eukaryotic Pathogen, Vector and Host Database Resources

More...VEuPathDBi		HostDB:ENSMUSG00000024902

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Keywords - Cellular componenti

Mitochondrion

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'PTM / Processing' section describes the extent of a transit peptide.<p><a href='/help/transit' target='_top'>More...</a></p>Transit peptidei1 – ?MitochondrionSequence analysis
<p>This subsection of the 'PTM / Processing' section describes the extent of a polypeptide chain in the mature protein following processing or proteolytic cleavage.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_0000030444? – 19239S ribosomal protein L11, mitochondrial

Proteomic databases

Encyclopedia of Proteome Dynamics

More...EPDi		Q9CQF0

MaxQB - The MaxQuant DataBase

More...MaxQBi		Q9CQF0

PaxDb, a database of protein abundance averages across all three domains of life

More...PaxDbi		Q9CQF0

PeptideAtlas

More...PeptideAtlasi		Q9CQF0

PRoteomics IDEntifications database

More...PRIDEi		Q9CQF0

ProteomicsDB: a multi-organism proteome resource

More...ProteomicsDBi		300518

PTM databases

iPTMnet integrated resource for PTMs in systems biology context

More...iPTMneti		Q9CQF0

Comprehensive resource for the study of protein post-translational modifications (PTMs) in human, mouse and rat.

More...PhosphoSitePlusi		Q9CQF0

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...Bgeei		ENSMUSG00000024902, Expressed in optic fissure and 308 other tissues

ExpressionAtlas, Differential and Baseline Expression

More...ExpressionAtlasi		Q9CQF0, baseline and differential

Genevisible search portal to normalized and curated expression data from Genevestigator

More...Genevisiblei		Q9CQF0, MM

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

<p>This subsection of the <a href="http://www.uniprot.org/help/interaction%5Fsection">'Interaction'</a> section provides information about the protein quaternary structure and interaction(s) with other proteins or protein complexes (with the exception of physiological receptor-ligand interactions which are annotated in the <a href="http://www.uniprot.org/help/function%5Fsection">'Function'</a> section).<p><a href='/help/subunit_structure' target='_top'>More...</a></p>Subunit structurei

Component of the mitochondrial ribosome large subunit (39S) which comprises a 16S rRNA and about 50 distinct proteins.

By similarity

Protein-protein interaction databases

The Biological General Repository for Interaction Datasets (BioGRID)

More...BioGRIDi		211460, 38 interactors

ComplexPortal: manually curated resource of macromolecular complexes

More...ComplexPortali		CPX-5302, 39S mitochondrial large ribosomal subunit

STRING: functional protein association networks

More...STRINGi		10090.ENSMUSP00000025836

Miscellaneous databases

RNAct, Protein-RNA interaction predictions for model organisms.

More...RNActi		Q9CQF0, protein

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

SWISS-MODEL Repository - a database of annotated 3D protein structure models

More...SMRi		Q9CQF0

Database of comparative protein structure models

More...ModBasei		Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

<p>This subsection of the 'Family and domains' section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Belongs to the universal ribosomal protein uL11 family.Curated

Keywords - Domaini

Transit peptide

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...eggNOGi		KOG3257, Eukaryota

Ensembl GeneTree

More...GeneTreei		ENSGT00390000003153

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...HOGENOMi		CLU_074237_1_1_1

InParanoid: Eukaryotic Ortholog Groups

More...InParanoidi		Q9CQF0

Identification of Orthologs from Complete Genome Data

More...OMAi		CKQFNAK

Database of Orthologous Groups

More...OrthoDBi		1346532at2759

Database for complete collections of gene phylogenies

More...PhylomeDBi		Q9CQF0

TreeFam database of animal gene trees

More...TreeFami		TF313471

Family and domain databases

Conserved Domains Database

More...CDDi		cd00349, Ribosomal_L11, 1 hit

Gene3D Structural and Functional Annotation of Protein Families

More...Gene3Di		1.10.10.250, 1 hit
3.30.1550.10, 1 hit

HAMAP database of protein families

More...HAMAPi		MF_00736, Ribosomal_L11, 1 hit

Integrated resource of protein families, domains and functional sites

More...InterProi		View protein in InterPro
IPR000911, Ribosomal_L11/L12
IPR036796, Ribosomal_L11/L12_N_sf
IPR006519, Ribosomal_L11_bac-typ
IPR020783, Ribosomal_L11_C
IPR036769, Ribosomal_L11_C_sf
IPR020784, Ribosomal_L11_N

The PANTHER Classification System

More...PANTHERi		PTHR11661, PTHR11661, 1 hit

Pfam protein domain database

More...Pfami		View protein in Pfam
PF00298, Ribosomal_L11, 1 hit
PF03946, Ribosomal_L11_N, 1 hit

Simple Modular Architecture Research Tool; a protein domain database

More...SMARTi		View protein in SMART
SM00649, RL11, 1 hit

Superfamily database of structural and functional annotation

More...SUPFAMi		SSF46906, SSF46906, 1 hit
SSF54747, SSF54747, 1 hit

TIGRFAMs; a protein family database

More...TIGRFAMsi		TIGR01632, L11_bact, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequence (1+)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is in its mature form or if it represents the precursor.<p><a href='/help/sequence_processing' target='_top'>More...</a></p>Sequence processingi: The displayed sequence is further processed into a mature form.

This entry has 1 described isoform and 3 potential isoforms that are computationally mapped.Show allAlign All

Q9CQF0-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MSKLSRATRT LKKPEAGGVI RSIVRAGQAI PGPPLGPILG QRGVSINQFC 
        60         70         80         90        100
KEFNEKTKDI KEGIPLPTKI FIKPDRTFEL KIGQPTVSYF LKAAAGIEKG 
       110        120        130        140        150
ARHTGKEVAG LVSLKHVYEI ACVKAKDDAF AMQDVPLSSV VRSIIGSARS 
       160        170        180        190 
LGIRVVKDLS AEELEAFQKE RAVFLAAQKE ADLAAQAEAA KK
Length:192
Mass (Da):20,680
Last modified:June 1, 2001 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i9530EFA4E41A81F3
GO

<p>In eukaryotic reference proteomes, unreviewed entries that are likely to belong to the same gene are computationally mapped, based on gene identifiers from Ensembl, EnsemblGenomes and model organism databases.<p><a href='/help/gene_centric_isoform_mapping' target='_top'>More...</a></p>Computationally mapped potential isoform sequencesi

There are 3 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
A0A494B9R3A0A494B9R3_MOUSE
39S ribosomal protein L11, mitochon...
Mrpl11
158Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
A0A494B9H5A0A494B9H5_MOUSE
39S ribosomal protein L11, mitochon...
Mrpl11
150Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
A0A494B915A0A494B915_MOUSE
39S ribosomal protein L11, mitochon...
Mrpl11
114Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...EMBLi

GenBank nucleotide sequence database

More...GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...DDBJi
Links Updated
AB049639 mRNA Translation: BAB40844.1
AK002797 mRNA Translation: BAB22366.1
AK010329 mRNA Translation: BAB26856.1
AK167247 mRNA Translation: BAE39368.1
BC046750 mRNA Translation: AAH46750.1

The Consensus CDS (CCDS) project

More...CCDSi		CCDS29444.1

NCBI Reference Sequences

More...RefSeqi		NP_079829.1, NM_025553.4

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...Ensembli		ENSMUST00000025836; ENSMUSP00000025836; ENSMUSG00000024902

Database of genes from NCBI RefSeq genomes

More...GeneIDi		66419

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...KEGGi		mmu:66419

UCSC genome browser

More...UCSCi		uc008gbt.2, mouse

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AB049639 mRNA Translation: BAB40844.1
AK002797 mRNA Translation: BAB22366.1
AK010329 mRNA Translation: BAB26856.1
AK167247 mRNA Translation: BAE39368.1
BC046750 mRNA Translation: AAH46750.1
CCDSiCCDS29444.1
RefSeqiNP_079829.1, NM_025553.4

3D structure databases

SMRiQ9CQF0
ModBaseiSearch...

Protein-protein interaction databases

BioGRIDi211460, 38 interactors
ComplexPortaliCPX-5302, 39S mitochondrial large ribosomal subunit
STRINGi10090.ENSMUSP00000025836

PTM databases

iPTMnetiQ9CQF0
PhosphoSitePlusiQ9CQF0

Proteomic databases

EPDiQ9CQF0
MaxQBiQ9CQF0
PaxDbiQ9CQF0
PeptideAtlasiQ9CQF0
PRIDEiQ9CQF0
ProteomicsDBi300518

Protocols and materials databases

Antibodypedia a portal for validated antibodies

More...Antibodypediai		30159, 312 antibodies from 30 providers

The DNASU plasmid repository

More...DNASUi		66419

Genome annotation databases

EnsembliENSMUST00000025836; ENSMUSP00000025836; ENSMUSG00000024902
GeneIDi66419
KEGGimmu:66419
UCSCiuc008gbt.2, mouse

Organism-specific databases

Comparative Toxicogenomics Database

More...CTDi		65003
MGIiMGI:2137215, Mrpl11
VEuPathDBiHostDB:ENSMUSG00000024902

Phylogenomic databases

eggNOGiKOG3257, Eukaryota
GeneTreeiENSGT00390000003153
HOGENOMiCLU_074237_1_1_1
InParanoidiQ9CQF0
OMAiCKQFNAK
OrthoDBi1346532at2759
PhylomeDBiQ9CQF0
TreeFamiTF313471

Enzyme and pathway databases

ReactomeiR-MMU-5389840, Mitochondrial translation elongation
R-MMU-5419276, Mitochondrial translation termination

Miscellaneous databases

BioGRID ORCS database of CRISPR phenotype screens

More...BioGRID-ORCSi		66419, 18 hits in 64 CRISPR screens

ChiTaRS: a database of human, mouse and fruit fly chimeric transcripts and RNA-sequencing data

More...ChiTaRSi		Mrpl11, mouse

Protein Ontology

More...PROi		PR:Q9CQF0
RNActiQ9CQF0, protein

The Stanford Online Universal Resource for Clones and ESTs

More...SOURCEi		Search...

Gene expression databases

BgeeiENSMUSG00000024902, Expressed in optic fissure and 308 other tissues
ExpressionAtlasiQ9CQF0, baseline and differential
GenevisibleiQ9CQF0, MM

Family and domain databases

CDDicd00349, Ribosomal_L11, 1 hit
Gene3Di1.10.10.250, 1 hit
3.30.1550.10, 1 hit
HAMAPiMF_00736, Ribosomal_L11, 1 hit
InterProiView protein in InterPro
IPR000911, Ribosomal_L11/L12
IPR036796, Ribosomal_L11/L12_N_sf
IPR006519, Ribosomal_L11_bac-typ
IPR020783, Ribosomal_L11_C
IPR036769, Ribosomal_L11_C_sf
IPR020784, Ribosomal_L11_N
PANTHERiPTHR11661, PTHR11661, 1 hit
PfamiView protein in Pfam
PF00298, Ribosomal_L11, 1 hit
PF03946, Ribosomal_L11_N, 1 hit
SMARTiView protein in SMART
SM00649, RL11, 1 hit
SUPFAMiSSF46906, SSF46906, 1 hit
SSF54747, SSF54747, 1 hit
TIGRFAMsiTIGR01632, L11_bact, 1 hit

MobiDB: a database of protein disorder and mobility annotations

More...MobiDBi		Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiRM11_MOUSE
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q9CQF0
Secondary accession number(s): Q3TJX7
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: July 26, 2002
Last sequence update: June 1, 2001
Last modified: February 23, 2022
This is version 149 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Reference proteome

Documents

  1. Ribosomal proteins
    Ribosomal proteins families and list of entries
  2. MGD cross-references
    Mouse Genome Database (MGD) cross-references in UniProtKB/Swiss-Prot
  3. SIMILARITY comments
    Index of protein domains and families
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