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Entry version 124 (29 Sep 2021)
Sequence version 1 (01 Jun 2001)
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Protein

Protein NipSnap homolog 3B

Gene

Nipsnap3b

Organism
Mus musculus (Mouse)
Status
Reviewed-Annotation score:

Annotation score:2 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Protein NipSnap homolog 3B
Short name:
NipSnap3B
Alternative name(s):
NipSnap-related protein
Protein NipSnap homolog 3A
Short name:
NipSnap3A
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:Nipsnap3b
Synonyms:Nipsnap3a
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiMus musculus (Mouse)
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri10090 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeMusMus
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000000589 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes_manual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 4

Organism-specific databases

Mouse genome database (MGD) from Mouse Genome Informatics (MGI)

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MGIi
MGI:1913786, Nipsnap3b

Eukaryotic Pathogen, Vector and Host Database Resources

More...
VEuPathDBi
HostDB:ENSMUSG00000015247

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywords - Cellular componenti

Cytoplasm

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'PTM / Processing' section describes the extent of a polypeptide chain in the mature protein following processing or proteolytic cleavage.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00002211551 – 247Protein NipSnap homolog 3BAdd BLAST247

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'PTM / Processing' section specifies the position and type of each modified residue excluding <a href="http://www.uniprot.org/manual/lipid">lipids</a>, <a href="http://www.uniprot.org/manual/carbohyd">glycans</a> and <a href="http://www.uniprot.org/manual/crosslnk">protein cross-links</a>.<p><a href='/help/mod_res' target='_top'>More...</a></p>Modified residuei45N6-succinyllysineCombined sources1
Modified residuei48N6-succinyllysineCombined sources1
Modified residuei57N6-succinyllysineCombined sources1
Modified residuei166N6-succinyllysineCombined sources1

Proteomic databases

Encyclopedia of Proteome Dynamics

More...
EPDi
Q9CQE1

jPOST - Japan Proteome Standard Repository/Database

More...
jPOSTi
Q9CQE1

MaxQB - The MaxQuant DataBase

More...
MaxQBi
Q9CQE1

PaxDb, a database of protein abundance averages across all three domains of life

More...
PaxDbi
Q9CQE1

PeptideAtlas

More...
PeptideAtlasi
Q9CQE1

PRoteomics IDEntifications database

More...
PRIDEi
Q9CQE1

ProteomicsDB: a multi-organism proteome resource

More...
ProteomicsDBi
293715

PTM databases

iPTMnet integrated resource for PTMs in systems biology context

More...
iPTMneti
Q9CQE1

Comprehensive resource for the study of protein post-translational modifications (PTMs) in human, mouse and rat.

More...
PhosphoSitePlusi
Q9CQE1

SwissPalm database of S-palmitoylation events

More...
SwissPalmi
Q9CQE1

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...
Bgeei
ENSMUSG00000015247, Expressed in liver and 291 other tissues

ExpressionAtlas, Differential and Baseline Expression

More...
ExpressionAtlasi
Q9CQE1, baseline and differential

Genevisible search portal to normalized and curated expression data from Genevestigator

More...
Genevisiblei
Q9CQE1, MM

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

Protein-protein interaction databases

The Biological General Repository for Interaction Datasets (BioGRID)

More...
BioGRIDi
211542, 4 interactors

Protein interaction database and analysis system

More...
IntActi
Q9CQE1, 1 interactor

Molecular INTeraction database

More...
MINTi
Q9CQE1

STRING: functional protein association networks

More...
STRINGi
10090.ENSMUSP00000015391

Miscellaneous databases

RNAct, Protein-RNA interaction predictions for model organisms.

More...
RNActi
Q9CQE1, protein

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

<p>This subsection of the 'Family and domains' section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Belongs to the NipSnap family.Curated

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
KOG2883, Eukaryota

Ensembl GeneTree

More...
GeneTreei
ENSGT00950000183018

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...
HOGENOMi
CLU_085919_0_1_1

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
Q9CQE1

Identification of Orthologs from Complete Genome Data

More...
OMAi
VHTHVNR

Database of Orthologous Groups

More...
OrthoDBi
1141024at2759

Database for complete collections of gene phylogenies

More...
PhylomeDBi
Q9CQE1

TreeFam database of animal gene trees

More...
TreeFami
TF314501

Family and domain databases

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR011008, Dimeric_a/b-barrel
IPR012577, NIPSNAP

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF07978, NIPSNAP, 2 hits

Superfamily database of structural and functional annotation

More...
SUPFAMi
SSF54909, SSF54909, 2 hits

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequence (1+)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

This entry has 1 described isoform and 1 potential isoform that is computationally mapped.Show allAlign All

Q9CQE1-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MLALRSGLRT ALAPRVLTPQ VCSPFATGPR QSNGTFYEFR TYFLKPSKTN
60 70 80 90 100
EFLENFKNSV HLRTAHSEMI GYWTVEFGGR TNRVFHIWKY DNFAHRTAVR
110 120 130 140 150
KALAKDKEWQ ERFLIPNLAF IDKQEVEITY LVPWCKIGTP PKEGVYELAT
160 170 180 190 200
FQMKPGGPAL WGNAFKRAVN AHVELGYSTL VGVFHTEYGA LNRVHVLWWN
210 220 230 240
ESADSRAAGR HWSHEDPRVV AAVRESVSYL ESQQNTFLIP TSFSPLK
Length:247
Mass (Da):28,308
Last modified:June 1, 2001 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i99791350D557956C
GO

<p>In eukaryotic reference proteomes, unreviewed entries that are likely to belong to the same gene are computationally mapped, based on gene identifiers from Ensembl, EnsemblGenomes and model organism databases.<p><a href='/help/gene_centric_isoform_mapping' target='_top'>More...</a></p>Computationally mapped potential isoform sequencesi

There is 1 potential isoform mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
B1AWZ5B1AWZ5_MOUSE
Protein NipSnap homolog 3B
Nipsnap3b
197Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Sequence' section reports difference(s) between the canonical sequence (displayed by default in the entry) and the different sequence submissions merged in the entry. These various submissions may originate from different sequencing projects, different types of experiments, or different biological samples. Sequence conflicts are usually of unknown origin.<p><a href='/help/conflict' target='_top'>More...</a></p>Sequence conflicti5R → L in AAL56225 (Ref. 1) Curated1
Sequence conflicti33N → D in AAL56225 (Ref. 1) Curated1
Sequence conflicti36F → L in AAL56225 (Ref. 1) Curated1

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

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EMBLi

GenBank nucleotide sequence database

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GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
AF353623 mRNA Translation: AAL56225.1
AK004458 mRNA Translation: BAB23312.1
AK008786 mRNA Translation: BAB25894.1
AK012480 mRNA Translation: BAB28269.1
AL772397 Genomic DNA No translation available.
CH466565 Genomic DNA Translation: EDL02287.1
BC019505 mRNA Translation: AAH19505.1

The Consensus CDS (CCDS) project

More...
CCDSi
CCDS18186.1

NCBI Reference Sequences

More...
RefSeqi
NP_079899.1, NM_025623.3

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...
Ensembli
ENSMUST00000015391; ENSMUSP00000015391; ENSMUSG00000015247

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
66536

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
mmu:66536

UCSC genome browser

More...
UCSCi
uc008swt.1, mouse

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF353623 mRNA Translation: AAL56225.1
AK004458 mRNA Translation: BAB23312.1
AK008786 mRNA Translation: BAB25894.1
AK012480 mRNA Translation: BAB28269.1
AL772397 Genomic DNA No translation available.
CH466565 Genomic DNA Translation: EDL02287.1
BC019505 mRNA Translation: AAH19505.1
CCDSiCCDS18186.1
RefSeqiNP_079899.1, NM_025623.3

3D structure databases

Database of comparative protein structure models

More...
ModBasei
Search...

SWISS-MODEL Interactive Workspace

More...
SWISS-MODEL-Workspacei
Submit a new modelling project...

Protein-protein interaction databases

BioGRIDi211542, 4 interactors
IntActiQ9CQE1, 1 interactor
MINTiQ9CQE1
STRINGi10090.ENSMUSP00000015391

PTM databases

iPTMnetiQ9CQE1
PhosphoSitePlusiQ9CQE1
SwissPalmiQ9CQE1

Proteomic databases

EPDiQ9CQE1
jPOSTiQ9CQE1
MaxQBiQ9CQE1
PaxDbiQ9CQE1
PeptideAtlasiQ9CQE1
PRIDEiQ9CQE1
ProteomicsDBi293715

Genome annotation databases

EnsembliENSMUST00000015391; ENSMUSP00000015391; ENSMUSG00000015247
GeneIDi66536
KEGGimmu:66536
UCSCiuc008swt.1, mouse

Organism-specific databases

Comparative Toxicogenomics Database

More...
CTDi
55335
MGIiMGI:1913786, Nipsnap3b
VEuPathDBiHostDB:ENSMUSG00000015247

Phylogenomic databases

eggNOGiKOG2883, Eukaryota
GeneTreeiENSGT00950000183018
HOGENOMiCLU_085919_0_1_1
InParanoidiQ9CQE1
OMAiVHTHVNR
OrthoDBi1141024at2759
PhylomeDBiQ9CQE1
TreeFamiTF314501

Miscellaneous databases

BioGRID ORCS database of CRISPR phenotype screens

More...
BioGRID-ORCSi
66536, 0 hits in 61 CRISPR screens

Protein Ontology

More...
PROi
PR:Q9CQE1
RNActiQ9CQE1, protein

The Stanford Online Universal Resource for Clones and ESTs

More...
SOURCEi
Search...

Gene expression databases

BgeeiENSMUSG00000015247, Expressed in liver and 291 other tissues
ExpressionAtlasiQ9CQE1, baseline and differential
GenevisibleiQ9CQE1, MM

Family and domain databases

InterProiView protein in InterPro
IPR011008, Dimeric_a/b-barrel
IPR012577, NIPSNAP
PfamiView protein in Pfam
PF07978, NIPSNAP, 2 hits
SUPFAMiSSF54909, SSF54909, 2 hits

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiNPS3B_MOUSE
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q9CQE1
Secondary accession number(s): B1AWZ4, Q8VHX9
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: April 26, 2004
Last sequence update: June 1, 2001
Last modified: September 29, 2021
This is version 124 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Reference proteome

Documents

  1. MGD cross-references
    Mouse Genome Database (MGD) cross-references in UniProtKB/Swiss-Prot
  2. SIMILARITY comments
    Index of protein domains and families
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