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Protein

Tetraspanin-31

Gene

Tspan31

Organism
Mus musculus (Mouse)
Status
Reviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

GO - Biological processi

  • cell surface receptor signaling pathway Source: GO_Central

Names & Taxonomyi

Protein namesi
Recommended name:
Tetraspanin-31
Short name:
Tspan-31
Alternative name(s):
Sarcoma-amplified sequence homolog
Gene namesi
Name:Tspan31
Synonyms:Sas
OrganismiMus musculus (Mouse)
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeMusMus
Proteomesi
  • UP000000589 Componenti: Chromosome 10

Organism-specific databases

MGIiMGI:1914375 Tspan31

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Topological domaini1 – 12CytoplasmicSequence analysisAdd BLAST12
Transmembranei13 – 33HelicalSequence analysisAdd BLAST21
Topological domaini34 – 44ExtracellularSequence analysisAdd BLAST11
Transmembranei45 – 65HelicalSequence analysisAdd BLAST21
Topological domaini66 – 72CytoplasmicSequence analysis7
Transmembranei73 – 93HelicalSequence analysisAdd BLAST21
Topological domaini94 – 173ExtracellularSequence analysisAdd BLAST80
Transmembranei174 – 194HelicalSequence analysisAdd BLAST21
Topological domaini195 – 210CytoplasmicSequence analysisAdd BLAST16

Keywords - Cellular componenti

Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00002192711 – 210Tetraspanin-31Add BLAST210

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Glycosylationi109N-linked (GlcNAc...) asparagineSequence analysis1
Glycosylationi117N-linked (GlcNAc...) asparagine1 Publication1
Glycosylationi134N-linked (GlcNAc...) asparagineSequence analysis1

Keywords - PTMi

Glycoprotein

Proteomic databases

EPDiQ9CQ88
MaxQBiQ9CQ88
PaxDbiQ9CQ88
PeptideAtlasiQ9CQ88
PRIDEiQ9CQ88

PTM databases

iPTMnetiQ9CQ88
PhosphoSitePlusiQ9CQ88
SwissPalmiQ9CQ88

Expressioni

Gene expression databases

BgeeiENSMUSG00000006736 Expressed in 282 organ(s), highest expression level in left lobe of liver
CleanExiMM_TSPAN31
GenevisibleiQ9CQ88 MM

Structurei

3D structure databases

ProteinModelPortaliQ9CQ88
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the tetraspanin (TM4SF) family.Curated

Keywords - Domaini

Transmembrane, Transmembrane helix

Phylogenomic databases

eggNOGiKOG3882 Eukaryota
ENOG4111IRY LUCA
GeneTreeiENSGT00500000044851
HOGENOMiHOG000005650
HOVERGENiHBG009195
InParanoidiQ9CQ88
KOiK17356
OMAiAWGKGFG
OrthoDBiEOG091G0PBF
PhylomeDBiQ9CQ88
TreeFamiTF323367

Family and domain databases

InterProiView protein in InterPro
IPR000301 Tetraspanin
IPR018499 Tetraspanin/Peripherin
PfamiView protein in Pfam
PF00335 Tetraspannin, 1 hit
PIRSFiPIRSF002419 Tetraspanin, 1 hit
PRINTSiPR00259 TMFOUR

Sequencei

Sequence statusi: Complete.

Q9CQ88-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MVCGGFACSR NALCALNVVY MLVGFLLIGV AAWGKGLGVV SSIHIIGGVI
60 70 80 90 100
AVGVFLLLIA VAGLVGAANH HQVLLFFYMI ILGLVFIFQF GISCSCLAIN
110 120 130 140 150
RNTQADVINA SWSVLSNSTR HELERSFDCC GLFNLTTLRL QDDTSCSAVC
160 170 180 190 200
KTKSSTCQMC GERFLKHSDK ALKILGGVGL FFSFTEILGV WLAMRFRNQK
210
DPRANPSAFL
Length:210
Mass (Da):22,694
Last modified:June 1, 2001 - v1
Checksum:iB1CAD508BEBCC9FD
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK012457 mRNA Translation: BAB28252.1
AK013523 mRNA Translation: BAB28897.1
AK014183 mRNA Translation: BAB29196.1
AK075962 mRNA Translation: BAC36084.1
BC023306 mRNA Translation: AAH23306.1
CCDSiCCDS24227.1
RefSeqiNP_080258.1, NM_025982.4
UniGeneiMm.35650

Genome annotation databases

EnsembliENSMUST00000060991; ENSMUSP00000057751; ENSMUSG00000006736
GeneIDi67125
KEGGimmu:67125
UCSCiuc007hhw.1 mouse

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK012457 mRNA Translation: BAB28252.1
AK013523 mRNA Translation: BAB28897.1
AK014183 mRNA Translation: BAB29196.1
AK075962 mRNA Translation: BAC36084.1
BC023306 mRNA Translation: AAH23306.1
CCDSiCCDS24227.1
RefSeqiNP_080258.1, NM_025982.4
UniGeneiMm.35650

3D structure databases

ProteinModelPortaliQ9CQ88
ModBaseiSearch...
MobiDBiSearch...

PTM databases

iPTMnetiQ9CQ88
PhosphoSitePlusiQ9CQ88
SwissPalmiQ9CQ88

Proteomic databases

EPDiQ9CQ88
MaxQBiQ9CQ88
PaxDbiQ9CQ88
PeptideAtlasiQ9CQ88
PRIDEiQ9CQ88

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSMUST00000060991; ENSMUSP00000057751; ENSMUSG00000006736
GeneIDi67125
KEGGimmu:67125
UCSCiuc007hhw.1 mouse

Organism-specific databases

CTDi6302
MGIiMGI:1914375 Tspan31

Phylogenomic databases

eggNOGiKOG3882 Eukaryota
ENOG4111IRY LUCA
GeneTreeiENSGT00500000044851
HOGENOMiHOG000005650
HOVERGENiHBG009195
InParanoidiQ9CQ88
KOiK17356
OMAiAWGKGFG
OrthoDBiEOG091G0PBF
PhylomeDBiQ9CQ88
TreeFamiTF323367

Miscellaneous databases

PROiPR:Q9CQ88
SOURCEiSearch...

Gene expression databases

BgeeiENSMUSG00000006736 Expressed in 282 organ(s), highest expression level in left lobe of liver
CleanExiMM_TSPAN31
GenevisibleiQ9CQ88 MM

Family and domain databases

InterProiView protein in InterPro
IPR000301 Tetraspanin
IPR018499 Tetraspanin/Peripherin
PfamiView protein in Pfam
PF00335 Tetraspannin, 1 hit
PIRSFiPIRSF002419 Tetraspanin, 1 hit
PRINTSiPR00259 TMFOUR
ProtoNetiSearch...

Entry informationi

Entry nameiTSN31_MOUSE
AccessioniPrimary (citable) accession number: Q9CQ88
Secondary accession number(s): Q9CUY7
Entry historyiIntegrated into UniProtKB/Swiss-Prot: April 26, 2005
Last sequence update: June 1, 2001
Last modified: November 7, 2018
This is version 111 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families
  2. MGD cross-references
    Mouse Genome Database (MGD) cross-references in UniProtKB/Swiss-Prot
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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