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Protein

NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 2, mitochondrial

Gene

Ndufb2

Organism
Mus musculus (Mouse)
Status
Reviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.By similarity

GO - Biological processi

Keywordsi

Biological processElectron transport, Respiratory chain, Transport

Enzyme and pathway databases

ReactomeiR-MMU-611105 Respiratory electron transport
R-MMU-6799198 Complex I biogenesis

Names & Taxonomyi

Protein namesi
Recommended name:
NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 2, mitochondrial
Alternative name(s):
Complex I-AGGG
Short name:
CI-AGGG
NADH-ubiquinone oxidoreductase AGGG subunit
Gene namesi
Name:Ndufb2
OrganismiMus musculus (Mouse)
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeMusMus
Proteomesi
  • UP000000589 Componenti: Chromosome 6

Organism-specific databases

MGIiMGI:1915448 Ndufb2

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

Membrane, Mitochondrion, Mitochondrion inner membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transit peptidei1 – 33MitochondrionBy similarityAdd BLAST33
ChainiPRO_000002004334 – 105NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 2, mitochondrialAdd BLAST72

Proteomic databases

MaxQBiQ9CPU2
PaxDbiQ9CPU2
PeptideAtlasiQ9CPU2
PRIDEiQ9CPU2
TopDownProteomicsiQ9CPU2

PTM databases

PhosphoSitePlusiQ9CPU2

Expressioni

Gene expression databases

BgeeiENSMUSG00000002416
GenevisibleiQ9CPU2 MM

Interactioni

Subunit structurei

Complex I is composed of 45 different subunits.By similarity

Protein-protein interaction databases

ComplexPortaliCPX-266 Mitochondrial respiratory chain complex I
CORUMiQ9CPU2
STRINGi10090.ENSMUSP00000114095

Structurei

3D structure databases

SMRiQ9CPU2
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the complex I NDUFB2 subunit family.Curated

Keywords - Domaini

Transit peptide

Phylogenomic databases

eggNOGiENOG410J0BK Eukaryota
ENOG41128HF LUCA
GeneTreeiENSGT00390000004044
HOGENOMiHOG000252974
HOVERGENiHBG006499
InParanoidiQ9CPU2
KOiK03958
OMAiEFFSATM
OrthoDBiEOG091G0YSW
PhylomeDBiQ9CPU2
TreeFamiTF316619

Family and domain databases

InterProiView protein in InterPro
IPR026627 NDUFB2
PANTHERiPTHR15223 PTHR15223, 1 hit
PfamiView protein in Pfam
PF14813 NADH_B2, 1 hit

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

Q9CPU2-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSALTRLVPF GRVGGRLLRG CRARAAGDSG VRHAGGGVHI QPRYREFPQL
60 70 80 90 100
TRSQVIQGEF LSSLMWFWIL WRFWHDSDAV LGHFSYPDPS QWTDEELGIP

PDDED
Length:105
Mass (Da):11,967
Last modified:June 1, 2001 - v1
Checksum:iF5D5019BFA33E510
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK007495 mRNA Translation: BAB25068.1
AK010642 mRNA Translation: BAB27084.1
AK019008 mRNA Translation: BAB31508.1
AK028334 mRNA Translation: BAC25887.1
BC013510 mRNA Translation: AAH13510.1
CCDSiCCDS20025.1
RefSeqiNP_080888.1, NM_026612.3
XP_006506592.1, XM_006506529.3
UniGeneiMm.29415

Genome annotation databases

EnsembliENSMUST00000119379; ENSMUSP00000114095; ENSMUSG00000002416
ENSMUST00000135671; ENSMUSP00000118918; ENSMUSG00000002416
GeneIDi68198
KEGGimmu:68198
UCSCiuc009bmc.1 mouse

Similar proteinsi

Entry informationi

Entry nameiNDUB2_MOUSE
AccessioniPrimary (citable) accession number: Q9CPU2
Entry historyiIntegrated into UniProtKB/Swiss-Prot: May 10, 2004
Last sequence update: June 1, 2001
Last modified: July 18, 2018
This is version 111 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

3D-structure, Complete proteome, Reference proteome

Documents

  1. MGD cross-references
    Mouse Genome Database (MGD) cross-references in UniProtKB/Swiss-Prot
  2. PDB cross-references
    Index of Protein Data Bank (PDB) cross-references
  3. SIMILARITY comments
    Index of protein domains and families

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