UniProtKB - Q9CEF5 (PKNB_LACLA)
Protein
Probable serine/threonine-protein kinase PknB
Gene
pknB
Organism
Lactococcus lactis subsp. lactis (strain IL1403) (Streptococcus lactis)
Status
Functioni
Catalytic activityi
Sites
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Binding sitei | 42 | ATPPROSITE-ProRule annotation | 1 | |
Active sitei | 136 | Proton acceptorPROSITE-ProRule annotation | 1 |
Regions
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Nucleotide bindingi | 18 – 26 | ATPPROSITE-ProRule annotation | 9 |
GO - Molecular functioni
- ATP binding Source: UniProtKB-KW
- protein serine kinase activity Source: UniProtKB-EC
- protein threonine kinase activity Source: UniProtKB-EC
Keywordsi
Molecular function | Kinase, Serine/threonine-protein kinase, Transferase |
Ligand | ATP-binding, Nucleotide-binding |
Enzyme and pathway databases
BioCyci | LLAC272623:L138452-MONOMER |
Names & Taxonomyi
Protein namesi | |
Gene namesi | Name:pknB Ordered Locus Names:LL1887 ORF Names:L138452 |
Organismi | Lactococcus lactis subsp. lactis (strain IL1403) (Streptococcus lactis) |
Taxonomic identifieri | 272623 [NCBI] |
Taxonomic lineagei | Bacteria › Firmicutes › Bacilli › Lactobacillales › Streptococcaceae › Lactococcus › |
Proteomesi |
|
PTM / Processingi
Molecule processing
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
ChainiPRO_0000171200 | 1 – 627 | Probable serine/threonine-protein kinase PknBAdd BLAST | 627 |
Proteomic databases
PaxDbi | Q9CEF5 |
Family & Domainsi
Domains and Repeats
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Domaini | 12 – 275 | Protein kinasePROSITE-ProRule annotationAdd BLAST | 264 | |
Domaini | 361 – 428 | PASTA 1PROSITE-ProRule annotationAdd BLAST | 68 | |
Domaini | 430 – 502 | PASTA 2PROSITE-ProRule annotationAdd BLAST | 73 | |
Domaini | 503 – 574 | PASTA 3PROSITE-ProRule annotationAdd BLAST | 72 |
Compositional bias
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Compositional biasi | 579 – 627 | Ser-richAdd BLAST | 49 |
Sequence similaritiesi
Keywords - Domaini
RepeatPhylogenomic databases
eggNOGi | COG0515, Bacteria COG2815, Bacteria |
HOGENOMi | CLU_000288_135_2_9 |
OMAi | DPDYRYQ |
Family and domain databases
InterProi | View protein in InterPro IPR011009, Kinase-like_dom_sf IPR005543, PASTA_dom IPR000719, Prot_kinase_dom IPR017441, Protein_kinase_ATP_BS IPR008271, Ser/Thr_kinase_AS |
Pfami | View protein in Pfam PF03793, PASTA, 3 hits PF00069, Pkinase, 1 hit |
SMARTi | View protein in SMART SM00740, PASTA, 3 hits SM00220, S_TKc, 1 hit |
SUPFAMi | SSF56112, SSF56112, 1 hit |
PROSITEi | View protein in PROSITE PS51178, PASTA, 3 hits PS00107, PROTEIN_KINASE_ATP, 1 hit PS50011, PROTEIN_KINASE_DOM, 1 hit PS00108, PROTEIN_KINASE_ST, 1 hit |
i Sequence
Sequence statusi: Complete.
Q9CEF5-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MIQIGKIFAD RYRIIKEIGR GGMANVYQGE DTFLGDRLVA IKVLRSNFEN
60 70 80 90 100
DDIAIARFQR EAFAMAELSH PNIVGISDVG EFESQQYIVM EFVDGMTLKQ
110 120 130 140 150
YINQNAPLAN DEAIEIITEI LSAMDMAHSH GIIHRDLKPQ NVLVSSSGTV
160 170 180 190 200
KVTDFGIAKA LSETSLTQTN TMFGSVHYLS PEQARGSNAT VQSDIYAIGI
210 220 230 240 250
ILFELLTGQI PFDGDSAVAI ALKHFQESIP SIINLNPEVP QALENVVIKA
260 270 280 290 300
TAKDIKNRYT DVEEMMTDVA TSTSLDRRGE EKLVFNKDHD ETKIMPANLI
310 320 330 340 350
NPYDTKPLID KKEDNDSQTD EKAASSEVGN KNKKSKKGLI IGLIILLLVV
360 370 380 390 400
GGATLAWVVS TPTNVKIPNV TNSTLSQAKS KIKDAKLKVG TVHKQQSSTI
410 420 430 440 450
AEGKVIKTDP TSGTTVRSNS SVDIYVSTGN EDIIKMKDFV GEKIDEAMAT
460 470 480 490 500
LLKDYGIDES QVTQTSVPSD SYPAGTIIKQ SPKKGSSFDT KGSEKITFEV
510 520 530 540 550
SSGKQVEVPD YKPNGQYMTY SQYQAALKAA GFTNITLDPQ ATTNQQADGY
560 570 580 590 600
VYSVYPNVGT SVDPTQEIVV TYSVYTAPSS SSTTSESTTT SETSSSTTSS
610 620
TSSSTTSQPS TDNNNSSKES STTSSSS
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AE005176 Genomic DNA Translation: AAK05985.1 |
PIRi | G86860 |
RefSeqi | NP_268044.1, NC_002662.1 WP_003130801.1, NC_002662.1 |
Genome annotation databases
EnsemblBacteriai | AAK05985; AAK05985; L138452 |
KEGGi | lla:L138452 |
PATRICi | fig|272623.7.peg.2021 |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AE005176 Genomic DNA Translation: AAK05985.1 |
PIRi | G86860 |
RefSeqi | NP_268044.1, NC_002662.1 WP_003130801.1, NC_002662.1 |
3D structure databases
SMRi | Q9CEF5 |
ModBasei | Search... |
Protein-protein interaction databases
STRINGi | 272623.L138452 |
Proteomic databases
PaxDbi | Q9CEF5 |
Genome annotation databases
EnsemblBacteriai | AAK05985; AAK05985; L138452 |
KEGGi | lla:L138452 |
PATRICi | fig|272623.7.peg.2021 |
Phylogenomic databases
eggNOGi | COG0515, Bacteria COG2815, Bacteria |
HOGENOMi | CLU_000288_135_2_9 |
OMAi | DPDYRYQ |
Enzyme and pathway databases
BioCyci | LLAC272623:L138452-MONOMER |
Family and domain databases
InterProi | View protein in InterPro IPR011009, Kinase-like_dom_sf IPR005543, PASTA_dom IPR000719, Prot_kinase_dom IPR017441, Protein_kinase_ATP_BS IPR008271, Ser/Thr_kinase_AS |
Pfami | View protein in Pfam PF03793, PASTA, 3 hits PF00069, Pkinase, 1 hit |
SMARTi | View protein in SMART SM00740, PASTA, 3 hits SM00220, S_TKc, 1 hit |
SUPFAMi | SSF56112, SSF56112, 1 hit |
PROSITEi | View protein in PROSITE PS51178, PASTA, 3 hits PS00107, PROTEIN_KINASE_ATP, 1 hit PS50011, PROTEIN_KINASE_DOM, 1 hit PS00108, PROTEIN_KINASE_ST, 1 hit |
ProtoNeti | Search... |
MobiDBi | Search... |
Entry informationi
Entry namei | PKNB_LACLA | |
Accessioni | Q9CEF5Primary (citable) accession number: Q9CEF5 | |
Entry historyi | Integrated into UniProtKB/Swiss-Prot: | April 4, 2003 |
Last sequence update: | June 1, 2001 | |
Last modified: | February 10, 2021 | |
This is version 109 of the entry and version 1 of the sequence. See complete history. | ||
Entry statusi | Reviewed (UniProtKB/Swiss-Prot) | |
Annotation program | Prokaryotic Protein Annotation Program |
Miscellaneousi
Keywords - Technical termi
Reference proteomeDocuments
- SIMILARITY comments
Index of protein domains and families