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Entry version 161 (29 Sep 2021)
Sequence version 2 (03 Apr 2002)
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Protein

Phospholipase D delta

Gene

PLDDELTA

Organism
Arabidopsis thaliana (Mouse-ear cress)
Status
Reviewed-Annotation score:

Annotation score:5 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Hydrolyzes glycerol-phospholipids at the terminal phosphodiesteric bond to generate phosphatidic acids (PA). May be involved in PA accumulation in the dehydration stress response and in the transduction of hormonal and environmental signals to the microtubules cytoskeleton (PubMed:11549769, PubMed:11489173, PubMed:12881496).

Prefers phosphatidylethanolamine to phosphatidylcholine as substrate (PubMed:12397060).

Involved in H2O2 and abscisic acid (ABA)-induced stomatal closure (PubMed:22589465, PubMed:22392280).

Involved in nitric oxide (NO) signaling during stomatal closure (PubMed:22932846).

Plays a positive role in ABA-promoted senescence (PubMed:23762411).

Involved in basal defense and nonhost resistance (PubMed:23979971).

9 Publications

<p>This subsection of the <a href="http://www.uniprot.org/help/function_section">Function</a> section describes the catalytic activity of an enzyme, i.e. a chemical reaction that the enzyme catalyzes.<p><a href='/help/catalytic_activity' target='_top'>More...</a></p>Catalytic activityi

<p>This subsection of the 'Function' section provides information relevant to cofactors. A cofactor is any non-protein substance required for a protein to be catalytically active. Some cofactors are inorganic, such as the metal atoms zinc, iron, and copper in various oxidation states. Others, such as most vitamins, are organic.<p><a href='/help/cofactor' target='_top'>More...</a></p>Cofactori

Ca2+1 PublicationNote: Ca2+. Requires millimolar level (PIP2-dependent).1 Publication

<p>This subsection of the <a href="http://www.uniprot.org/help/function_section">Function</a> section describes regulatory mechanisms for enzymes, transporters or microbial transcription factors, and reports the components which regulate (by activation or inhibition) the reaction.<p><a href='/help/activity_regulation' target='_top'>More...</a></p>Activity regulationi

Activated by free oleic acid in a dose-dependent manner and less effectively by other unsaturated fatty acids such as linoleic and linolenic acids (PubMed:11706190). Not activated by the saturated fatty acids stearic and palmitic acids (PubMed:11706190). PIP2 and Ca2+ stimulate activity by promoting lipid substrate binding to the active site (PubMed:12397060). Activated by H2O2 and by binding to GAPC (PubMed:14508007, PubMed:22589465).4 Publications

<p>This subsection of the 'Function' section describes biophysical and chemical properties, such as maximal absorption, kinetic parameters, pH dependence, redox potentials and temperature dependence.<p><a href='/help/biophysicochemical_properties' target='_top'>More...</a></p>Kineticsi

  1. Vmax=1.0 µmol/min/mg enzyme with phosphatidylcholine as substrate1 Publication
  2. Vmax=1.5 µmol/min/mg enzyme with phosphatidylethanolamine as substrate1 Publication

pH dependencei

Optimum pH is between 6.0 and 7.0.1 Publication

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/function_section">Function</a> section indicates at which position the protein binds a given metal ion. The nature of the metal is indicated in the 'Description' field.<p><a href='/help/metal' target='_top'>More...</a></p>Metal bindingi216CalciumBy similarity1
<p>This subsection of the <a href="http://www.uniprot.org/help/function_section">Function</a> section is used for enzymes and indicates the residues directly involved in catalysis.<p><a href='/help/act_site' target='_top'>More...</a></p>Active sitei373PROSITE-ProRule annotation1
<p>This subsection of the <a href="http://www.uniprot.org/help/function_section">Function</a> section describes the interaction between a single amino acid and another chemical entity. Priority is given to the annotation of physiological ligands.<p><a href='/help/binding' target='_top'>More...</a></p>Binding sitei3731,2-diacyl-sn-glycero-3-phosphateBy similarity1
Active sitei375PROSITE-ProRule annotation1
Active sitei380PROSITE-ProRule annotation1
Metal bindingi409CalciumBy similarity1
Metal bindingi440CalciumBy similarity1
Binding sitei5881,2-diacyl-sn-glycero-3-phosphateBy similarity1
Active sitei718PROSITE-ProRule annotation1
Binding sitei7181,2-diacyl-sn-glycero-3-phosphateBy similarity1
Active sitei720PROSITE-ProRule annotation1
Active sitei725PROSITE-ProRule annotation1
Metal bindingi781CalciumBy similarity1

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

GO - Biological processi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Molecular functionHydrolase
Biological processLipid degradation, Lipid metabolism, Stress response
LigandCalcium, Metal-binding

Enzyme and pathway databases

BioCyc Collection of Pathway/Genome Databases

More...
BioCyci
ARA:AT4G35790-MONOMER
MetaCyc:AT4G35790-MONOMER

BRENDA Comprehensive Enzyme Information System

More...
BRENDAi
3.1.4.4, 399

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Phospholipase D delta1 Publication (EC:3.1.4.42 Publications)
Short name:
AtPLDdelta1 Publication
Short name:
PLD delta1 Publication
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:PLDDELTA1 Publication
Ordered Locus Names:At4g35790Imported
ORF Names:F4B14.60Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiArabidopsis thaliana (Mouse-ear cress)
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri3702 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliopsidaeudicotyledonsGunneridaePentapetalaerosidsmalvidsBrassicalesBrassicaceaeCamelineaeArabidopsis
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000006548 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes_manual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 4

Organism-specific databases

Arabidopsis Information Portal

More...
Araporti
AT4G35790

The Arabidopsis Information Resource

More...
TAIRi
locus:2125314, AT4G35790

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Keywords - Cellular componenti

Cell membrane, Membrane

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

<p>This subsection of the 'Pathology and Biotech' section describes the in vivo effects caused by ablation of the gene (or one or more transcripts) coding for the protein described in the entry. This includes gene knockout and knockdown, provided experiments have been performed in the context of a whole organism or a specific tissue, and not at the single-cell level.<p><a href='/help/disruption_phenotype' target='_top'>More...</a></p>Disruption phenotypei

No visible phenotype when grown under standard conditions (PubMed:22932846). Loss of oleate-activated PLD activity and increased sensitivity to stress damage and to H2O2-induced cell death (PubMed:14508007). Hypersensitivity to hyperosmotic stress (PubMed:19017627). Impaired stomatal closure in response to nitric oxide donor (PubMed:22932846). Attenuated lipid degradation retarding abscisic acid (ABA)-promoted leaf senescence (PubMed:23762411). Decreased penetration resistance against non-host fungi (PubMed:23979971). No effect on ABA-induced stomatal closure (PubMed:22392280). Pldalpha1 and plddelta double mutants have a suppressed ABA-induced stomatal closure (PubMed:22392280).6 Publications

Mutagenesis

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/manual/pathology_and_biotech_section">'Pathology and Biotech'</a> section describes the effect of the experimental mutation of one or more amino acid(s) on the biological properties of the protein.<p><a href='/help/mutagen' target='_top'>More...</a></p>Mutagenesisi410R → P: Total loss of activity. 1 Publication1
Mutagenesisi622R → D: Loss of 80% of PIP2-stimulated activity and only 50% of oleate-stimulated activity. 1 Publication1

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'PTM / Processing' section describes the extent of a polypeptide chain in the mature protein following processing or proteolytic cleavage.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00002188151 – 868Phospholipase D deltaAdd BLAST868

Proteomic databases

PaxDb, a database of protein abundance averages across all three domains of life

More...
PaxDbi
Q9C5Y0

PRoteomics IDEntifications database

More...
PRIDEi
Q9C5Y0

ProteomicsDB: a multi-organism proteome resource

More...
ProteomicsDBi
236633 [Q9C5Y0-1]

PTM databases

SwissPalm database of S-palmitoylation events

More...
SwissPalmi
Q9C5Y0

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

<p>This subsection of the 'Expression' section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms. By default, the information is derived from experiments at the mRNA level, unless specified 'at protein level'.<br></br>Examples: <a href="http://www.uniprot.org/uniprot/P92958#expression">P92958</a>, <a href="http://www.uniprot.org/uniprot/Q8TDN4#expression">Q8TDN4</a>, <a href="http://www.uniprot.org/uniprot/O14734#expression">O14734</a><p><a href='/help/tissue_specificity' target='_top'>More...</a></p>Tissue specificityi

Expressed in roots, leaves, stems, siliques and flowers (PubMed:11706190, PubMed:11489173). Strongly expressed in the vascular tissues of cotyledons and leaves under dehydration stress conditions (PubMed:11489173). Expression is higher in old leaves than in young leaves (PubMed:11706190). Expressed in leaves and guard cells (PubMed:22932846). The isoform 2 may not be present in siliques.3 Publications

<p>This subsection of the 'Expression' section reports the experimentally proven effects of inducers and repressors (usually chemical compounds or environmental factors) on the level of protein (or mRNA) expression (up-regulation, down-regulation, constitutive expression).<p><a href='/help/induction' target='_top'>More...</a></p>Inductioni

By salt stress or dehydration, in vascular tissues of roots, cotyledons and leaves (PubMed:11489173, PubMed:19017627). Not induced cold stress (PubMed:11489173). Up-regulated by abscisic acid in rosette leaves (PubMed:22932846, PubMed:22392280).4 Publications

Gene expression databases

ExpressionAtlas, Differential and Baseline Expression

More...
ExpressionAtlasi
Q9C5Y0, baseline and differential

Genevisible search portal to normalized and curated expression data from Genevestigator

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Genevisiblei
Q9C5Y0, AT

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

<p>This subsection of the <a href="http://www.uniprot.org/help/interaction_section">'Interaction'</a> section provides information about the protein quaternary structure and interaction(s) with other proteins or protein complexes (with the exception of physiological receptor-ligand interactions which are annotated in the <a href="http://www.uniprot.org/help/function_section">'Function'</a> section).<p><a href='/help/subunit_structure' target='_top'>More...</a></p>Subunit structurei

Interacts with GAPC1 and GAPC2. Increased interaction in the presence of H2O2.

1 Publication

Protein-protein interaction databases

The Biological General Repository for Interaction Datasets (BioGRID)

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BioGRIDi
15015, 5 interactors

Protein interaction database and analysis system

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IntActi
Q9C5Y0, 1 interactor

STRING: functional protein association networks

More...
STRINGi
3702.AT4G35790.1

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

SWISS-MODEL Repository - a database of annotated 3D protein structure models

More...
SMRi
Q9C5Y0

Database of comparative protein structure models

More...
ModBasei
Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family_and_domains_section">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini1 – 154C2PROSITE-ProRule annotationAdd BLAST154
Domaini368 – 403PLD phosphodiesterase 1PROSITE-ProRule annotationAdd BLAST36
Domaini713 – 740PLD phosphodiesterase 2PROSITE-ProRule annotationAdd BLAST28

<p>This subsection of the 'Family and domains' section provides general information on the biological role of a domain. The term 'domain' is intended here in its wide acceptation, it may be a structural domain, a transmembrane region or a functional domain. Several domains are described in this subsection.<p><a href='/help/domain_cc' target='_top'>More...</a></p>Domaini

C2 domain is a calcium-binding fold, and the binding promotes the protein association with membranes. In PLD delta, all the calcium-coordinating acidic amino acids are conserved.Curated

<p>This subsection of the 'Family and domains' section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Keywords - Domaini

Repeat

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

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eggNOGi
KOG1329, Eukaryota

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
Q9C5Y0

Identification of Orthologs from Complete Genome Data

More...
OMAi
CLGKREK

Database of Orthologous Groups

More...
OrthoDBi
181485at2759

Database for complete collections of gene phylogenies

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PhylomeDBi
Q9C5Y0

Family and domain databases

Gene3D Structural and Functional Annotation of Protein Families

More...
Gene3Di
2.60.40.150, 1 hit

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR000008, C2_dom
IPR035892, C2_domain_sf
IPR001736, PLipase_D/transphosphatidylase
IPR024632, PLipase_D_C
IPR015679, PLipase_D_fam
IPR011402, PLipase_D_pln

The PANTHER Classification System

More...
PANTHERi
PTHR18896, PTHR18896, 1 hit

Pfam protein domain database

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Pfami
View protein in Pfam
PF00168, C2, 1 hit
PF12357, PLD_C, 1 hit
PF00614, PLDc, 2 hits

PIRSF; a whole-protein classification database

More...
PIRSFi
PIRSF036470, PLD_plant, 1 hit

Simple Modular Architecture Research Tool; a protein domain database

More...
SMARTi
View protein in SMART
SM00239, C2, 1 hit
SM00155, PLDc, 2 hits

Superfamily database of structural and functional annotation

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SUPFAMi
SSF49562, SSF49562, 1 hit

PROSITE; a protein domain and family database

More...
PROSITEi
View protein in PROSITE
PS50004, C2, 1 hit
PS50035, PLD, 2 hits

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequences (2+)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

This entry describes 2 <p>This subsection of the 'Sequence' section lists the alternative protein sequences (isoforms) that can be generated from the same gene by a single or by the combination of up to four biological events (alternative promoter usage, alternative splicing, alternative initiation and ribosomal frameshifting). Additionally, this section gives relevant information on each alternative protein isoform.<p><a href='/help/alternative_products' target='_top'>More...</a></p> isoformsi produced by alternative splicing. AlignAdd to basket

This entry has 2 described isoforms and 1 potential isoform that is computationally mapped.Show allAlign All

Isoform 1 (identifier: Q9C5Y0-1) [UniParc]FASTAAdd to basket
Also known as: PLD delta a

This isoform has been chosen as the <div> <p><b>What is the canonical sequence?</b><p><a href='/help/canonical_and_isoforms' target='_top'>More...</a></p>canonicali sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

« Hide
        10         20         30         40         50
MAEKVSEDVM LLHGDLDLKI VKARRLPNMD MFSEHLRRLF TACNACARPT
60 70 80 90 100
DTDDVDPRDK GEFGDKNIRS HRKVITSDPY VTVVVPQATL ARTRVLKNSQ
110 120 130 140 150
EPLWDEKFNI SIAHPFAYLE FQVKDDDVFG AQIIGTAKIP VRDIASGERI
160 170 180 190 200
SGWFPVLGAS GKPPKAETAI FIDMKFTPFD QIHSYRCGIA GDPERRGVRR
210 220 230 240 250
TYFPVRKGSQ VRLYQDAHVM DGTLPAIGLD NGKVYEHGKC WEDICYAISE
260 270 280 290 300
AHHMIYIVGW SIFHKIKLVR ETKVPRDKDM TLGELLKYKS QEGVRVLLLV
310 320 330 340 350
WDDKTSHDKF GIKTPGVMGT HDEETRKFFK HSSVICVLSP RYASSKLGLF
360 370 380 390 400
KQQASPSSSI YIMTVVGTLF THHQKCVLVD TQAVGNNRKV TAFIGGLDLC
410 420 430 440 450
DGRYDTPEHR ILHDLDTVFK DDFHNPTFPA GTKAPRQPWH DLHCRIDGPA
460 470 480 490 500
AYDVLINFEQ RWRKATRWKE FSLRLKGKTH WQDDALIRIG RISWILSPVF
510 520 530 540 550
KFLKDGTSII PEDDPCVWVS KEDDPENWHV QIFRSIDSGS VKGFPKYEDE
560 570 580 590 600
AEAQHLECAK RLVVDKSIQT AYIQTIRSAQ HFIYIENQYF LGSSYAWPSY
610 620 630 640 650
RDAGADNLIP MELALKIVSK IRAKERFAVY VVIPLWPEGD PKSGPVQEIL
660 670 680 690 700
YWQSQTMQMM YDVIAKELKA VQSDAHPLDY LNFYCLGKRE QLPDDMPATN
710 720 730 740 750
GSVVSDSYNF QRFMIYVHAK GMIVDDEYVL MGSANINQRS MAGTKDTEIA
760 770 780 790 800
MGAYQPNHTW AHKGRHPRGQ VYGYRMSLWA EHLGKTGDEF VEPSDLECLK
810 820 830 840 850
KVNTISEENW KRFIDPKFSE LQGHLIKYPL QVDVDGKVSP LPDYETFPDV
860
GGKIIGAHSM ALPDTLTT
Length:868
Mass (Da):98,917
Last modified:April 3, 2002 - v2
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:iAC18289664685178
GO
Isoform 2 (identifier: Q9C5Y0-2) [UniParc]FASTAAdd to basket
Also known as: PLD delta b

The sequence of this isoform differs from the canonical sequence as follows:
     354-364: Missing.

Show »
Length:857
Mass (Da):97,779
Checksum:i111B50FD1E9D22A0
GO

<p>In eukaryotic reference proteomes, unreviewed entries that are likely to belong to the same gene are computationally mapped, based on gene identifiers from Ensembl, EnsemblGenomes and model organism databases.<p><a href='/help/gene_centric_isoform_mapping' target='_top'>More...</a></p>Computationally mapped potential isoform sequencesi

There is 1 potential isoform mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
F4JNU6F4JNU6_ARATH
Phospholipase D
PLDDELTA ATPLDDELTA, PHOSPHOLIPASE D, phospholipase D delta, At4g35790, F4B14.60
693Annotation score:

Annotation score:3 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>

<p>This subsection of the 'Sequence' section reports difference(s) between the protein sequence shown in the UniProtKB entry and other available protein sequences derived from the same gene.<p><a href='/help/sequence_caution' target='_top'>More...</a></p>Sequence cautioni

The sequence AAL11625 differs from that shown. Reason: Frameshift.Curated
The sequence CAA21465 differs from that shown. Reason: Erroneous gene model prediction.Curated
The sequence CAB81488 differs from that shown. Reason: Erroneous gene model prediction.Curated

Alternative sequence

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Sequence' section describes the sequence of naturally occurring alternative protein isoform(s). The changes in the amino acid sequence may be due to alternative splicing, alternative promoter usage, alternative initiation, or ribosomal frameshifting.<p><a href='/help/var_seq' target='_top'>More...</a></p>Alternative sequenceiVSP_005029354 – 364Missing in isoform 2. 4 PublicationsAdd BLAST11

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

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GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

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DDBJi
Links Updated
AF322228 mRNA Translation: AAG53975.1
AF274239 mRNA Translation: AAL02150.1
AF306345 mRNA Translation: AAL11978.1
AB031047 mRNA Translation: BAB19130.1
AL031986 Genomic DNA Translation: CAA21465.1 Sequence problems.
AL161588 Genomic DNA Translation: CAB81488.1 Sequence problems.
CP002687 Genomic DNA Translation: AEE86571.1
CP002687 Genomic DNA Translation: AEE86572.1
AF424632 mRNA Translation: AAL11625.1 Frameshift.
AY113045 mRNA Translation: AAM47353.1
AK227213 mRNA Translation: BAE99251.1

NCBI Reference Sequences

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RefSeqi
NP_567989.1, NM_119745.3 [Q9C5Y0-1]
NP_849501.1, NM_179170.3 [Q9C5Y0-2]

Genome annotation databases

Ensembl plant genome annotation project

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EnsemblPlantsi
AT4G35790.1; AT4G35790.1; AT4G35790 [Q9C5Y0-1]
AT4G35790.2; AT4G35790.2; AT4G35790 [Q9C5Y0-2]

Database of genes from NCBI RefSeq genomes

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GeneIDi
829733

Gramene; a comparative resource for plants

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Gramenei
AT4G35790.1; AT4G35790.1; AT4G35790 [Q9C5Y0-1]
AT4G35790.2; AT4G35790.2; AT4G35790 [Q9C5Y0-2]

KEGG: Kyoto Encyclopedia of Genes and Genomes

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KEGGi
ath:AT4G35790

Keywords - Coding sequence diversityi

Alternative splicing

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF322228 mRNA Translation: AAG53975.1
AF274239 mRNA Translation: AAL02150.1
AF306345 mRNA Translation: AAL11978.1
AB031047 mRNA Translation: BAB19130.1
AL031986 Genomic DNA Translation: CAA21465.1 Sequence problems.
AL161588 Genomic DNA Translation: CAB81488.1 Sequence problems.
CP002687 Genomic DNA Translation: AEE86571.1
CP002687 Genomic DNA Translation: AEE86572.1
AF424632 mRNA Translation: AAL11625.1 Frameshift.
AY113045 mRNA Translation: AAM47353.1
AK227213 mRNA Translation: BAE99251.1
RefSeqiNP_567989.1, NM_119745.3 [Q9C5Y0-1]
NP_849501.1, NM_179170.3 [Q9C5Y0-2]

3D structure databases

SMRiQ9C5Y0
ModBaseiSearch...

Protein-protein interaction databases

BioGRIDi15015, 5 interactors
IntActiQ9C5Y0, 1 interactor
STRINGi3702.AT4G35790.1

PTM databases

SwissPalmiQ9C5Y0

Proteomic databases

PaxDbiQ9C5Y0
PRIDEiQ9C5Y0
ProteomicsDBi236633 [Q9C5Y0-1]

Genome annotation databases

EnsemblPlantsiAT4G35790.1; AT4G35790.1; AT4G35790 [Q9C5Y0-1]
AT4G35790.2; AT4G35790.2; AT4G35790 [Q9C5Y0-2]
GeneIDi829733
GrameneiAT4G35790.1; AT4G35790.1; AT4G35790 [Q9C5Y0-1]
AT4G35790.2; AT4G35790.2; AT4G35790 [Q9C5Y0-2]
KEGGiath:AT4G35790

Organism-specific databases

AraportiAT4G35790
TAIRilocus:2125314, AT4G35790

Phylogenomic databases

eggNOGiKOG1329, Eukaryota
InParanoidiQ9C5Y0
OMAiCLGKREK
OrthoDBi181485at2759
PhylomeDBiQ9C5Y0

Enzyme and pathway databases

BioCyciARA:AT4G35790-MONOMER
MetaCyc:AT4G35790-MONOMER
BRENDAi3.1.4.4, 399

Miscellaneous databases

Protein Ontology

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PROi
PR:Q9C5Y0

Gene expression databases

ExpressionAtlasiQ9C5Y0, baseline and differential
GenevisibleiQ9C5Y0, AT

Family and domain databases

Gene3Di2.60.40.150, 1 hit
InterProiView protein in InterPro
IPR000008, C2_dom
IPR035892, C2_domain_sf
IPR001736, PLipase_D/transphosphatidylase
IPR024632, PLipase_D_C
IPR015679, PLipase_D_fam
IPR011402, PLipase_D_pln
PANTHERiPTHR18896, PTHR18896, 1 hit
PfamiView protein in Pfam
PF00168, C2, 1 hit
PF12357, PLD_C, 1 hit
PF00614, PLDc, 2 hits
PIRSFiPIRSF036470, PLD_plant, 1 hit
SMARTiView protein in SMART
SM00239, C2, 1 hit
SM00155, PLDc, 2 hits
SUPFAMiSSF49562, SSF49562, 1 hit
PROSITEiView protein in PROSITE
PS50004, C2, 1 hit
PS50035, PLD, 2 hits

MobiDB: a database of protein disorder and mobility annotations

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MobiDBi
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiPLDD1_ARATH
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q9C5Y0
Secondary accession number(s): Q0WUE7
, Q8L891, Q944P8, Q947R2, Q9FS18, Q9SZS7
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: April 3, 2002
Last sequence update: April 3, 2002
Last modified: September 29, 2021
This is version 161 of the entry and version 2 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Reference proteome

Documents

  1. Arabidopsis thaliana
    Arabidopsis thaliana: entries and gene names
  2. SIMILARITY comments
    Index of protein domains and families
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