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Protein

Glutamate receptor 2.8

Gene

GLR2.8

Organism
Arabidopsis thaliana (Mouse-ear cress)
Status
Reviewed-Annotation score: -Experimental evidence at transcript leveli

Functioni

Glutamate-gated receptor that probably acts as non-selective cation channel. May be involved in light-signal transduction and calcium homeostasis via the regulation of calcium influx into cells.

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionIon channel, Ligand-gated ion channel, Receptor
Biological processIon transport, Transport

Names & Taxonomyi

Protein namesi
Recommended name:
Glutamate receptor 2.8
Alternative name(s):
Ligand-gated ion channel 2.8
Gene namesi
Name:GLR2.8
Synonyms:GLUR9
Ordered Locus Names:At2g29110
ORF Names:T9I4.19
OrganismiArabidopsis thaliana (Mouse-ear cress)
Taxonomic identifieri3702 [NCBI]
Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaeudicotyledonsGunneridaePentapetalaerosidsmalvidsBrassicalesBrassicaceaeCamelineaeArabidopsis
Proteomesi
  • UP000006548 Componenti: Chromosome 2

Organism-specific databases

AraportiAT2G29110
TAIRilocus:2066086 AT2G29110

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cell wall Cytoskeleton Vacuole Chloroplast Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertion Graphics by Christian Stolte; Source: COMPARTMENTS

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Topological domaini27 – 577ExtracellularSequence analysisAdd BLAST551
Transmembranei578 – 598HelicalSequence analysisAdd BLAST21
Topological domaini599 – 607CytoplasmicSequence analysis9
Transmembranei608 – 628HelicalSequence analysisAdd BLAST21
Topological domaini629 – 632CytoplasmicSequence analysis4
Transmembranei633 – 653HelicalSequence analysisAdd BLAST21
Topological domaini654 – 819ExtracellularSequence analysisAdd BLAST166
Transmembranei820 – 840HelicalSequence analysisAdd BLAST21
Topological domaini841 – 947CytoplasmicSequence analysisAdd BLAST107

Keywords - Cellular componenti

Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Signal peptidei1 – 26Sequence analysisAdd BLAST26
ChainiPRO_000001160327 – 947Glutamate receptor 2.8Add BLAST921

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Glycosylationi42N-linked (GlcNAc...) asparagineSequence analysis1
Glycosylationi118N-linked (GlcNAc...) asparagineSequence analysis1
Glycosylationi333N-linked (GlcNAc...) asparagineSequence analysis1
Glycosylationi341N-linked (GlcNAc...) asparagineSequence analysis1
Glycosylationi348N-linked (GlcNAc...) asparagineSequence analysis1
Glycosylationi420N-linked (GlcNAc...) asparagineSequence analysis1
Glycosylationi478N-linked (GlcNAc...) asparagineSequence analysis1
Glycosylationi524N-linked (GlcNAc...) asparagineSequence analysis1
Glycosylationi659N-linked (GlcNAc...) asparagineSequence analysis1
Glycosylationi704N-linked (GlcNAc...) asparagineSequence analysis1
Glycosylationi723N-linked (GlcNAc...) asparagineSequence analysis1
Glycosylationi779N-linked (GlcNAc...) asparagineSequence analysis1

Keywords - PTMi

Glycoprotein

Proteomic databases

PaxDbiQ9C5V5

Expressioni

Tissue specificityi

Expressed predominantly in leaves.1 Publication

Gene expression databases

ExpressionAtlasiQ9C5V5 differential
GenevisibleiQ9C5V5 AT

Interactioni

Subunit structurei

May form heteromers.By similarity

Protein-protein interaction databases

STRINGi3702.AT2G29110.1

Structurei

3D structure databases

ProteinModelPortaliQ9C5V5
SMRiQ9C5V5
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Keywords - Domaini

Signal, Transmembrane, Transmembrane helix

Phylogenomic databases

eggNOGiKOG1052 Eukaryota
ENOG410XQQV LUCA
HOGENOMiHOG000239558
InParanoidiQ9C5V5
KOiK05387
OMAiTRWKHPT
OrthoDBiEOG0936061T
PhylomeDBiQ9C5V5

Family and domain databases

InterProiView protein in InterPro
IPR001828 ANF_lig-bd_rcpt
IPR001320 Iontro_rcpt
IPR017103 Iontropic_Glu_rcpt_pln
IPR028082 Peripla_BP_I
IPR001638 Solute-binding_3/MltF_N
PfamiView protein in Pfam
PF01094 ANF_receptor, 1 hit
PF00060 Lig_chan, 1 hit
PF00497 SBP_bac_3, 1 hit
PIRSFiPIRSF037090 Iontro_Glu-like_rcpt_pln, 1 hit
SMARTiView protein in SMART
SM00079 PBPe, 1 hit
SUPFAMiSSF53822 SSF53822, 1 hit

Sequence (1+)i

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

This entry has 1 described isoform and 1 potential isoform that is computationally mapped.Show allAlign All

Q9C5V5-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MNPKKNNNTF LSYFVCLFLL LEVGLGQNQI SEIKVGVVLD LNTTFSKICL
60 70 80 90 100
TSINLALSDF YKDHPNYRTR LALHVRDSMK DTVQASAAAL DLIQNEQVSA
110 120 130 140 150
IIGPIDSMQA KFMIKLANKT QVPTISFSAT SPLLTSIKSD YFVRGTIDDS
160 170 180 190 200
YQVKAIAAIF ESFGWRSVVA IYVDNELGEG IMPYLFDALQ DVQVDRSVIP
210 220 230 240 250
SEANDDQILK ELYKLMTRQT RVFVVHMASR LASRIFEKAT EIGMMEEGYV
260 270 280 290 300
WLMTNGMTHM MRHIHHGRSL NTIDGVLGVR SHVPKSKGLE DFRLRWKRNF
310 320 330 340 350
KKENPWLRDD LSIFGLWAYD STTALAMAVE KTNISSFPYN NASGSSNNMT
360 370 380 390 400
DLGTLHVSRY GPSLLEALSE IRFNGLAGRF NLIDRQLESP KFEIINFVGN
410 420 430 440 450
EERIVGFWTP SNGLVNVNSN KTTSFTGERF GPLIWPGKST IVPKGWEIPT
460 470 480 490 500
NGKKIKVGVP VKKGFFNFVE VITDPITNIT TPKGYAIDIF EAALKKLPYS
510 520 530 540 550
VIPQYYRFES PDDDYDDLVY KVDNGTLDAV VGDVTITAYR SLYADFTLPY
560 570 580 590 600
TESGVSMMVP VRDNENKNTW VFLKPWGLDL WVTTACFFVL IGFVVWLFEH
610 620 630 640 650
RVNTDFRGPP HHQIGTSFWF SFSTMVFAHR EKVVSNLARF VVVVWCFVVL
660 670 680 690 700
VLTQSYTANL TSFLTVQRFQ PAAINVKDLI KNGDYVGYQH GAFVKDFLIK
710 720 730 740 750
EGFNVSKLKP FGSSEECHAL LSNGSISAAF DEVAYLRAIL SQYCSKYAIV
760 770 780 790 800
EPTFKTAGFG FAFPRNSPLT GDVSKAILNV TQGDEMQHIE NKWFMKQNDC
810 820 830 840 850
PDPKTALSSN RLSLRSFWGL FLIAGIASFL ALLIFVFLFL YENRHTLCDD
860 870 880 890 900
SEDSIWRKLT SLFRNFDEKD IKSHTFKSSA VHHVSSPMTQ YIPSPSTLQI
910 920 930 940
APRPHSPSQD RAFELRRVSF TPNEERLTTQ TIHFEDEESD IECVVEQ
Length:947
Mass (Da):107,189
Last modified:January 16, 2004 - v2
Checksum:iD519F97B813B0BA8
GO

Computationally mapped potential isoform sequencesi

There is 1 potential isoform mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
A0A178VW76A0A178VW76_ARATH
Glutamate receptor
GLR2.8 ATGLR2.8, glutamate receptor 2.8, At2g29110, T9I4.19, T9I4_19
948Annotation score:

Sequence cautioni

The sequence AAC33237 differs from that shown. Reason: Erroneous gene model prediction.Curated

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Sequence conflicti552E → G in CAC29254 (PubMed:11379626).Curated1
Sequence conflicti700K → Q in CAC29254 (PubMed:11379626).Curated1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AJ311495 mRNA Translation: CAC29254.1
AC005315 Genomic DNA Translation: AAC33237.1 Sequence problems.
CP002685 Genomic DNA Translation: AEC08212.1
PIRiT02741
RefSeqiNP_180475.2, NM_128468.2
UniGeneiAt.13039

Genome annotation databases

EnsemblPlantsiAT2G29110.1; AT2G29110.1; AT2G29110
GeneIDi817459
GrameneiAT2G29110.1; AT2G29110.1; AT2G29110
KEGGiath:AT2G29110

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AJ311495 mRNA Translation: CAC29254.1
AC005315 Genomic DNA Translation: AAC33237.1 Sequence problems.
CP002685 Genomic DNA Translation: AEC08212.1
PIRiT02741
RefSeqiNP_180475.2, NM_128468.2
UniGeneiAt.13039

3D structure databases

ProteinModelPortaliQ9C5V5
SMRiQ9C5V5
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi3702.AT2G29110.1

Proteomic databases

PaxDbiQ9C5V5

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblPlantsiAT2G29110.1; AT2G29110.1; AT2G29110
GeneIDi817459
GrameneiAT2G29110.1; AT2G29110.1; AT2G29110
KEGGiath:AT2G29110

Organism-specific databases

AraportiAT2G29110
TAIRilocus:2066086 AT2G29110

Phylogenomic databases

eggNOGiKOG1052 Eukaryota
ENOG410XQQV LUCA
HOGENOMiHOG000239558
InParanoidiQ9C5V5
KOiK05387
OMAiTRWKHPT
OrthoDBiEOG0936061T
PhylomeDBiQ9C5V5

Miscellaneous databases

PROiPR:Q9C5V5

Gene expression databases

ExpressionAtlasiQ9C5V5 differential
GenevisibleiQ9C5V5 AT

Family and domain databases

InterProiView protein in InterPro
IPR001828 ANF_lig-bd_rcpt
IPR001320 Iontro_rcpt
IPR017103 Iontropic_Glu_rcpt_pln
IPR028082 Peripla_BP_I
IPR001638 Solute-binding_3/MltF_N
PfamiView protein in Pfam
PF01094 ANF_receptor, 1 hit
PF00060 Lig_chan, 1 hit
PF00497 SBP_bac_3, 1 hit
PIRSFiPIRSF037090 Iontro_Glu-like_rcpt_pln, 1 hit
SMARTiView protein in SMART
SM00079 PBPe, 1 hit
SUPFAMiSSF53822 SSF53822, 1 hit
ProtoNetiSearch...

Entry informationi

Entry nameiGLR28_ARATH
AccessioniPrimary (citable) accession number: Q9C5V5
Secondary accession number(s): O81079
Entry historyiIntegrated into UniProtKB/Swiss-Prot: January 16, 2004
Last sequence update: January 16, 2004
Last modified: November 7, 2018
This is version 118 of the entry and version 2 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families
  2. Arabidopsis thaliana
    Arabidopsis thaliana: entries and gene names
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