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Entry version 111 (12 Aug 2020)
Sequence version 1 (01 Jun 2001)
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Protein

Uncharacterized AAA domain-containing protein P22H7.05c

Gene

pi026

Organism
Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Status
Reviewed-Annotation score:

Annotation score:2 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Protein inferred from homologyi <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/function%5Fsection">Function</a> section describes a region in the protein which binds nucleotide phosphates. It always involves more than one amino acid and includes all residues involved in nucleotide-binding.<p><a href='/help/np_bind' target='_top'>More...</a></p>Nucleotide bindingi413 – 420ATPSequence analysis8

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

GO - Biological processi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

LigandATP-binding, Nucleotide-binding

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Uncharacterized AAA domain-containing protein P22H7.05c
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
ORF Names:pi026, SPBP22H7.05c
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiSchizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri284812 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaTaphrinomycotinaSchizosaccharomycetesSchizosaccharomycetalesSchizosaccharomycetaceaeSchizosaccharomyces
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000002485 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome II

Organism-specific databases

Eukaryotic Pathogen Database Resources

More...
EuPathDBi
FungiDB:SPBP22H7.05c

Schizosaccharomyces pombe database

More...
PomBasei
SPBP22H7.05c

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cell wall Cytoskeleton Vacuole Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte & Seán O’Donoghue; Source: COMPARTMENTS

Keywords - Cellular componenti

Nucleus

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'PTM / Processing' section describes the extent of a polypeptide chain in the mature protein following processing or proteolytic cleavage.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00003102831 – 1201Uncharacterized AAA domain-containing protein P22H7.05cAdd BLAST1201

Proteomic databases

PaxDb, a database of protein abundance averages across all three domains of life

More...
PaxDbi
Q9C0W2

PRoteomics IDEntifications database

More...
PRIDEi
Q9C0W2

PTM databases

iPTMnet integrated resource for PTMs in systems biology context

More...
iPTMneti
Q9C0W2

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

GO - Molecular functioni

Protein-protein interaction databases

The Biological General Repository for Interaction Datasets (BioGRID)

More...
BioGRIDi
277800, 34 interactors

STRING: functional protein association networks

More...
STRINGi
4896.SPBP22H7.05c.1

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

SWISS-MODEL Repository - a database of annotated 3D protein structure models

More...
SMRi
Q9C0W2

Database of comparative protein structure models

More...
ModBasei
Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

<p>This subsection of the 'Family and domains' section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Belongs to the AAA ATPase family.Curated

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
KOG0732, Eukaryota

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...
HOGENOMi
CLU_000536_6_3_1

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
Q9C0W2

Identification of Orthologs from Complete Genome Data

More...
OMAi
RSRYKKF

Database for complete collections of gene phylogenies

More...
PhylomeDBi
Q9C0W2

Family and domain databases

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR003593, AAA+_ATPase
IPR041569, AAA_lid_3
IPR003959, ATPase_AAA_core
IPR003960, ATPase_AAA_CS
IPR027417, P-loop_NTPase

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF00004, AAA, 2 hits
PF17862, AAA_lid_3, 1 hit

Simple Modular Architecture Research Tool; a protein domain database

More...
SMARTi
View protein in SMART
SM00382, AAA, 1 hit

Superfamily database of structural and functional annotation

More...
SUPFAMi
SSF52540, SSF52540, 2 hits

PROSITE; a protein domain and family database

More...
PROSITEi
View protein in PROSITE
PS00674, AAA, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

Q9C0W2-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MRRRARSIRF SSDDNEDNEE DDDYYSNAHS EKSEDHSNHI KVSHFDPSSY
60 70 80 90 100
KQKLVSVRET QRNRKFSSLQ KHLNTETPSF SVSIENPSKP SAAFNDASLG
110 120 130 140 150
KKSTEHQIDG IRNGSSNLQM EGNDKELDTD NNEDESTTFK DEEDDLISPK
160 170 180 190 200
SYLTSSKTFS YPKAPTESTN GDYLDEDYVD GQSDPESSNA SDSDFADSPD
210 220 230 240 250
DLTKVRSPIP SRRGRRKRKM RGPILPVKKN LRVKKAMSPL RAERNSPDFR
260 270 280 290 300
RKLRSRDNRP NYHLFDYYNE IASSPNPSTT KITYNPPKLP MKDFATLPIG
310 320 330 340 350
YQSTCDSDET SELSSTSSEQ TSDVEGLNAY NNLGASSDIE NAPSSQLHFG
360 370 380 390 400
HIDEKTIRST DPFANRENLD FNSIGGLEDI ILQLKEMVML PLLYPEVFLH
410 420 430 440 450
LHITPPRGVL FHGPPGTGKT LMARVLAANC STKNQKISFF LRKGSDCLSK
460 470 480 490 500
WVGEAERQLR LLFEEARRVQ PSIIFFDEID GLAPIRSSKQ EQTHSSIVST
510 520 530 540 550
LLALMDGLDT RGQVVVIGAT NRPNDLDPAL RRPGRFDREF YFPLPNKQAR
560 570 580 590 600
MKILEINSLH FSPKIPESYL LHLAESTSGY GGADLKALCT EAALNAVRRT
610 620 630 640 650
FPQIYTSSDK FLIDLNEISV SICDFVVASE KIAVSTRRSD VKPNIPITDS
660 670 680 690 700
HKILFKKSIE VITSKIRRLL KLDVYLPTVE SLQKLPAEEL MRQKEINSLK
710 720 730 740 750
TTMSFRPRLL ITDIYGYGCT YLSKVLFSML DGIHVQSLDI SELLMDTTTS
760 770 780 790 800
PRSLLTKIFS EARKNAPSII FINNVEKWPS LFSHSFLSMF LLLLDSISPL
810 820 830 840 850
EPVMLLGFAN TNQEKLSSTV RSWFPSHRSE YHDLSFPDYS SRYSFFHYLL
860 870 880 890 900
KRISFLPIHQ KSAEAASVDI LPKVLPVSKT SDLTDKVNRR QRKNDKKIKN
910 920 930 940 950
KIQVKLSSIL EMLRSRYKKF KKPIIDLNDI YIDESNERVV KGKSKDNFEY
960 970 980 990 1000
FLSGNTVTRK KDNACFKMMN FEEIERRLWS GRYCTPKEFL RDIKMIKQDA
1010 1020 1030 1040 1050
ILSGDVNLKH KAKEMFAHAE LNVDELIDAK LLYDCCQVSK REKAYKQLKQ
1060 1070 1080 1090 1100
KKLNNAKDAH EMQESKNEET FVRNDVAQED NFIELSSNEV RNVSNDEHKH
1110 1120 1130 1140 1150
TLFHGQSLTH NNLIAVTPPS RTGVEHKEEN KKYDNVNIQK TLAKCAEEFA
1160 1170 1180 1190 1200
EHTNFNKVEL LDFVYSKLSS TIWENREEHD LLKIVRDVRQ TFFRSLEDMG

V
Length:1,201
Mass (Da):137,385
Last modified:June 1, 2001 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:iFEB8D759048697B4
GO

<p>This subsection of the 'Sequence' section reports difference(s) between the protein sequence shown in the UniProtKB entry and other available protein sequences derived from the same gene.<p><a href='/help/sequence_caution' target='_top'>More...</a></p>Sequence cautioni

The sequence BAA21405 differs from that shown. Reason: Erroneous initiation.Curated

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

More...
GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
AB004535 Genomic DNA Translation: BAA21405.1 Different initiation.
CU329671 Genomic DNA Translation: CAC37373.1

NCBI Reference Sequences

More...
RefSeqi
NP_595602.1, NM_001021497.2

Genome annotation databases

Ensembl fungal genome annotation project

More...
EnsemblFungii
SPBP22H7.05c.1; SPBP22H7.05c.1:pep; SPBP22H7.05c

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
2541287

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
spo:SPBP22H7.05c

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AB004535 Genomic DNA Translation: BAA21405.1 Different initiation.
CU329671 Genomic DNA Translation: CAC37373.1
RefSeqiNP_595602.1, NM_001021497.2

3D structure databases

SMRiQ9C0W2
ModBaseiSearch...

Protein-protein interaction databases

BioGRIDi277800, 34 interactors
STRINGi4896.SPBP22H7.05c.1

PTM databases

iPTMnetiQ9C0W2

Proteomic databases

PaxDbiQ9C0W2
PRIDEiQ9C0W2

Genome annotation databases

EnsemblFungiiSPBP22H7.05c.1; SPBP22H7.05c.1:pep; SPBP22H7.05c
GeneIDi2541287
KEGGispo:SPBP22H7.05c

Organism-specific databases

EuPathDBiFungiDB:SPBP22H7.05c
PomBaseiSPBP22H7.05c

Phylogenomic databases

eggNOGiKOG0732, Eukaryota
HOGENOMiCLU_000536_6_3_1
InParanoidiQ9C0W2
OMAiRSRYKKF
PhylomeDBiQ9C0W2

Miscellaneous databases

Protein Ontology

More...
PROi
PR:Q9C0W2

Family and domain databases

InterProiView protein in InterPro
IPR003593, AAA+_ATPase
IPR041569, AAA_lid_3
IPR003959, ATPase_AAA_core
IPR003960, ATPase_AAA_CS
IPR027417, P-loop_NTPase
PfamiView protein in Pfam
PF00004, AAA, 2 hits
PF17862, AAA_lid_3, 1 hit
SMARTiView protein in SMART
SM00382, AAA, 1 hit
SUPFAMiSSF52540, SSF52540, 2 hits
PROSITEiView protein in PROSITE
PS00674, AAA, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

More...
ProtoNeti
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiYHI5_SCHPO
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q9C0W2
Secondary accession number(s): O13617
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: November 13, 2007
Last sequence update: June 1, 2001
Last modified: August 12, 2020
This is version 111 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Reference proteome

Documents

  1. Schizosaccharomyces pombe
    Schizosaccharomyces pombe: entries and gene names
  2. SIMILARITY comments
    Index of protein domains and families
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