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UniProtKB - Q9C0V1 (AMT1_SCHPO)

Entry version 114 (25 May 2022)
Sequence version 1 (01 Jun 2001)
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Protein

Ammonium transporter 1

Gene

amt1

Organism
Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Status
Reviewed-Annotation score:

Annotation score:3 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>-Protein inferred from homologyi <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Transporter for ammonium to use as a nitrogen source. Under ammonium limitation acts as an ammonium sensor, generating a signal that leads to pseudohyphal growth.

1 Publication

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

  • ammonium transmembrane transporter activity Source: GO_Central
  • high-affinity secondary active ammonium transmembrane transporter activity Source: PomBase
Complete GO annotation on QuickGO ...

GO - Biological processi

Complete GO annotation on QuickGO ...

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Biological processAmmonia transport, Transport

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Ammonium transporter 1
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:amt1
ORF Names:SPCPB1C11.01
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiSchizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri284812 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryota › Fungi › Dikarya › Ascomycota › Taphrinomycotina › Schizosaccharomycetes › Schizosaccharomycetales › Schizosaccharomycetaceae › Schizosaccharomyces ›
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000002485 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome III

Organism-specific databases

Schizosaccharomyces pombe database

More...PomBasei		SPCPB1C11.01, amt1

Eukaryotic Pathogen, Vector and Host Database Resources

More...VEuPathDBi		FungiDB:SPCPB1C11.01

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/subcellular%5Flocation%5Fsection">'Subcellular location'</a> section describes the subcellular compartment where each non-membrane region of a membrane-spanning protein is found.<p><a href='/help/topo_dom' target='_top'>More...</a></p>Topological domaini1 – 32ExtracellularSequence analysisAdd BLAST32
<p>This subsection of the <a href="http://www.uniprot.org/help/subcellular%5Flocation%5Fsection">'Subcellular location'</a> section describes the extent of a membrane-spanning region of the protein. It denotes the presence of both alpha-helical transmembrane regions and the membrane spanning regions of beta-barrel transmembrane proteins.<p><a href='/help/transmem' target='_top'>More...</a></p>Transmembranei33 – 53HelicalSequence analysisAdd BLAST21
Topological domaini54 – 63CytoplasmicSequence analysis10
Transmembranei64 – 84HelicalSequence analysisAdd BLAST21
Topological domaini85 – 122ExtracellularSequence analysisAdd BLAST38
Transmembranei123 – 143HelicalSequence analysisAdd BLAST21
Topological domaini144 – 150CytoplasmicSequence analysis7
Transmembranei151 – 171HelicalSequence analysisAdd BLAST21
Topological domaini172 – 187ExtracellularSequence analysisAdd BLAST16
Transmembranei188 – 208HelicalSequence analysisAdd BLAST21
Topological domaini209 – 223CytoplasmicSequence analysisAdd BLAST15
Transmembranei224 – 244HelicalSequence analysisAdd BLAST21
Topological domaini245 – 253ExtracellularSequence analysis9
Transmembranei254 – 274HelicalSequence analysisAdd BLAST21
Topological domaini275 – 281CytoplasmicSequence analysis7
Transmembranei282 – 302HelicalSequence analysisAdd BLAST21
Topological domaini303ExtracellularSequence analysis1
Transmembranei304 – 324HelicalSequence analysisAdd BLAST21
Topological domaini325 – 338CytoplasmicSequence analysisAdd BLAST14
Transmembranei339 – 359HelicalSequence analysisAdd BLAST21
Topological domaini360 – 394ExtracellularSequence analysisAdd BLAST35
Transmembranei395 – 415HelicalSequence analysisAdd BLAST21
Topological domaini416 – 497CytoplasmicSequence analysisAdd BLAST82

Keywords - Cellular componenti

Membrane

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'PTM / Processing' section describes the extent of a polypeptide chain in the mature protein following processing or proteolytic cleavage.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00002783871 – 497Ammonium transporter 1Add BLAST497

Proteomic databases

MaxQB - The MaxQuant DataBase

More...MaxQBi		Q9C0V1

PaxDb, a database of protein abundance averages across all three domains of life

More...PaxDbi		Q9C0V1

PTM databases

iPTMnet integrated resource for PTMs in systems biology context

More...iPTMneti		Q9C0V1

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

Protein-protein interaction databases

The Biological General Repository for Interaction Datasets (BioGRID)

More...BioGRIDi		275898, 37 interactors

STRING: functional protein association networks

More...STRINGi		4896.SPCPB1C11.01.1

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

AlphaFold Protein Structure Database

More...AlphaFoldDBi		Q9C0V1

SWISS-MODEL Repository - a database of annotated 3D protein structure models

More...SMRi		Q9C0V1

Database of comparative protein structure models

More...ModBasei		Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes a region of interest that cannot be described in other subsections.<p><a href='/help/region' target='_top'>More...</a></p>Regioni440 – 497DisorderedSequence analysisAdd BLAST58

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes the position of regions of compositional bias within the protein and the particular type of amino acids that are over-represented within those regions.<p><a href='/help/compbias' target='_top'>More...</a></p>Compositional biasi446 – 466Polar residuesSequence analysisAdd BLAST21
Compositional biasi467 – 490Basic and acidic residuesSequence analysisAdd BLAST24

<p>This subsection of the 'Family and domains' section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Belongs to the ammonia transporter channel (TC 1.A.11.2) family. [View classification]Curated

Keywords - Domaini

Transmembrane, Transmembrane helix

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...eggNOGi		KOG0682, Eukaryota

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...HOGENOMi		CLU_000445_33_0_1

InParanoid: Eukaryotic Ortholog Groups

More...InParanoidi		Q9C0V1

Identification of Orthologs from Complete Genome Data

More...OMAi		ITPACGE

Database for complete collections of gene phylogenies

More...PhylomeDBi		Q9C0V1

Family and domain databases

Gene3D Structural and Functional Annotation of Protein Families

More...Gene3Di		1.10.3430.10, 1 hit

Integrated resource of protein families, domains and functional sites

More...InterProi		View protein in InterPro
IPR029020, Ammonium/urea_transptr
IPR001905, Ammonium_transpt
IPR018047, Ammonium_transpt_CS
IPR024041, NH4_transpt_AmtB-like_dom

The PANTHER Classification System

More...PANTHERi		PTHR43029, PTHR43029, 1 hit

Pfam protein domain database

More...Pfami		View protein in Pfam
PF00909, Ammonium_transp, 1 hit

TIGRFAMs; a protein family database

More...TIGRFAMsi		TIGR00836, amt, 1 hit

PROSITE; a protein domain and family database

More...PROSITEi		View protein in PROSITE
PS01219, AMMONIUM_TRANSP, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

Q9C0V1-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MSSTTDATPT PSGVNGGDSM TVNLNQFYNN GDVAWILTST ALVFIMIPGV 
        60         70         80         90        100
GFFYSGLARR RSAISMLFLS MMSVAIVAFQ WFFWGYSLTF SHEGGPYIGS 
       110        120        130        140        150
LANFGLRQTL GRPSSGASSV PDILFCVFQG MFAAITPALA IGAAADRGRM 
       160        170        180        190        200
FPCMVFMFLW TSIVYDPIAF WTWNPNGWLN KLGSYDFAGG SPVHISSGMA 
       210        220        230        240        250
ALAYSIVIGK RCDHGTTKYR PHNVPHVVLG TVFLWFGWFG FNGGSSAAAN 
       260        270        280        290        300
MRGVMAVVVT HLAASVGGIV WCVIDFAKNR HWSVVGFCEG AVAGLVAITP 
       310        320        330        340        350
GSGFVPPWAA VVIGALGAVF CYAATYLKKI IRVDDALDIF AEHGVGGMVG 
       360        370        380        390        400
NILTALFAAD YIEALDGSGT AYTGGWITHH YIQLGYQLAD TVSCAAYSFA 
       410        420        430        440        450
VSCALLFVMN YIPGLSLRVS REDEVLGLDK IELGESAYYY KDSTDEPPPI 
       460        470        480        490 
TTSGVQYTSP TVSDSASNEK EQEHRAQNEA QKEEEYRAES EAQAPAI
Length:497
Mass (Da):53,387
Last modified:June 1, 2001 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:iF3A5212635AFB9C7
GO

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...EMBLi

GenBank nucleotide sequence database

More...GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...DDBJi
Links Updated
CU329672 Genomic DNA Translation: CAC36934.1

NCBI Reference Sequences

More...RefSeqi		NP_588424.1, NM_001023415.2

Genome annotation databases

Ensembl fungal genome annotation project

More...EnsemblFungii		SPCPB1C11.01.1; SPCPB1C11.01.1:pep; SPCPB1C11.01

Database of genes from NCBI RefSeq genomes

More...GeneIDi		2539332

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...KEGGi		spo:SPCPB1C11.01

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CU329672 Genomic DNA Translation: CAC36934.1
RefSeqiNP_588424.1, NM_001023415.2

3D structure databases

AlphaFoldDBiQ9C0V1
SMRiQ9C0V1
ModBaseiSearch...

Protein-protein interaction databases

BioGRIDi275898, 37 interactors
STRINGi4896.SPCPB1C11.01.1

PTM databases

iPTMnetiQ9C0V1

Proteomic databases

MaxQBiQ9C0V1
PaxDbiQ9C0V1

Genome annotation databases

EnsemblFungiiSPCPB1C11.01.1; SPCPB1C11.01.1:pep; SPCPB1C11.01
GeneIDi2539332
KEGGispo:SPCPB1C11.01

Organism-specific databases

PomBaseiSPCPB1C11.01, amt1
VEuPathDBiFungiDB:SPCPB1C11.01

Phylogenomic databases

eggNOGiKOG0682, Eukaryota
HOGENOMiCLU_000445_33_0_1
InParanoidiQ9C0V1
OMAiITPACGE
PhylomeDBiQ9C0V1

Miscellaneous databases

Protein Ontology

More...PROi		PR:Q9C0V1

Family and domain databases

Gene3Di1.10.3430.10, 1 hit
InterProiView protein in InterPro
IPR029020, Ammonium/urea_transptr
IPR001905, Ammonium_transpt
IPR018047, Ammonium_transpt_CS
IPR024041, NH4_transpt_AmtB-like_dom
PANTHERiPTHR43029, PTHR43029, 1 hit
PfamiView protein in Pfam
PF00909, Ammonium_transp, 1 hit
TIGRFAMsiTIGR00836, amt, 1 hit
PROSITEiView protein in PROSITE
PS01219, AMMONIUM_TRANSP, 1 hit

MobiDB: a database of protein disorder and mobility annotations

More...MobiDBi		Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiAMT1_SCHPO
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q9C0V1
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: February 20, 2007
Last sequence update: June 1, 2001
Last modified: May 25, 2022
This is version 114 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Reference proteome

Documents

  1. Schizosaccharomyces pombe
    Schizosaccharomyces pombe: entries and gene names
  2. SIMILARITY comments
    Index of protein domains and families
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