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UniProtKB - Q9C0V1 (AMT1_SCHPO)
Protein
Ammonium transporter 1
Gene
amt1
Organism
Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Status
Functioni
Transporter for ammonium to use as a nitrogen source. Under ammonium limitation acts as an ammonium sensor, generating a signal that leads to pseudohyphal growth.
1 PublicationGO - Molecular functioni
- ammonium transmembrane transporter activity Source: GO_Central
- high-affinity secondary active ammonium transmembrane transporter activity Source: PomBase
GO - Biological processi
- ammonium transmembrane transport Source: PomBase
- nitrogen utilization Source: GO_Central
Keywordsi
Biological process | Ammonia transport, Transport |
Names & Taxonomyi
Protein namesi | Recommended name: Ammonium transporter 1 |
Gene namesi | Name:amt1 ORF Names:SPCPB1C11.01 |
Organismi | Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast) |
Taxonomic identifieri | 284812 [NCBI] |
Taxonomic lineagei | Eukaryota › Fungi › Dikarya › Ascomycota › Taphrinomycotina › Schizosaccharomycetes › Schizosaccharomycetales › Schizosaccharomycetaceae › Schizosaccharomyces › |
Proteomesi |
|
Organism-specific databases
PomBasei | SPCPB1C11.01, amt1 |
VEuPathDBi | FungiDB:SPCPB1C11.01 |
Subcellular locationi
Other locations
- Membrane 1 Publication; Multi-pass membrane protein 1 Publication
Golgi apparatus
- Golgi apparatus Source: PomBase
Plasma Membrane
- integral component of plasma membrane Source: PomBase
Topology
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Topological domaini | 1 – 32 | ExtracellularSequence analysisAdd BLAST | 32 | |
Transmembranei | 33 – 53 | HelicalSequence analysisAdd BLAST | 21 | |
Topological domaini | 54 – 63 | CytoplasmicSequence analysis | 10 | |
Transmembranei | 64 – 84 | HelicalSequence analysisAdd BLAST | 21 | |
Topological domaini | 85 – 122 | ExtracellularSequence analysisAdd BLAST | 38 | |
Transmembranei | 123 – 143 | HelicalSequence analysisAdd BLAST | 21 | |
Topological domaini | 144 – 150 | CytoplasmicSequence analysis | 7 | |
Transmembranei | 151 – 171 | HelicalSequence analysisAdd BLAST | 21 | |
Topological domaini | 172 – 187 | ExtracellularSequence analysisAdd BLAST | 16 | |
Transmembranei | 188 – 208 | HelicalSequence analysisAdd BLAST | 21 | |
Topological domaini | 209 – 223 | CytoplasmicSequence analysisAdd BLAST | 15 | |
Transmembranei | 224 – 244 | HelicalSequence analysisAdd BLAST | 21 | |
Topological domaini | 245 – 253 | ExtracellularSequence analysis | 9 | |
Transmembranei | 254 – 274 | HelicalSequence analysisAdd BLAST | 21 | |
Topological domaini | 275 – 281 | CytoplasmicSequence analysis | 7 | |
Transmembranei | 282 – 302 | HelicalSequence analysisAdd BLAST | 21 | |
Topological domaini | 303 | ExtracellularSequence analysis | 1 | |
Transmembranei | 304 – 324 | HelicalSequence analysisAdd BLAST | 21 | |
Topological domaini | 325 – 338 | CytoplasmicSequence analysisAdd BLAST | 14 | |
Transmembranei | 339 – 359 | HelicalSequence analysisAdd BLAST | 21 | |
Topological domaini | 360 – 394 | ExtracellularSequence analysisAdd BLAST | 35 | |
Transmembranei | 395 – 415 | HelicalSequence analysisAdd BLAST | 21 | |
Topological domaini | 416 – 497 | CytoplasmicSequence analysisAdd BLAST | 82 |
Keywords - Cellular componenti
MembranePTM / Processingi
Molecule processing
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
ChainiPRO_0000278387 | 1 – 497 | Ammonium transporter 1Add BLAST | 497 |
Proteomic databases
MaxQBi | Q9C0V1 |
PaxDbi | Q9C0V1 |
PTM databases
iPTMneti | Q9C0V1 |
Interactioni
Protein-protein interaction databases
BioGRIDi | 275898, 37 interactors |
STRINGi | 4896.SPCPB1C11.01.1 |
Family & Domainsi
Region
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Regioni | 440 – 497 | DisorderedSequence analysisAdd BLAST | 58 |
Compositional bias
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Compositional biasi | 446 – 466 | Polar residuesSequence analysisAdd BLAST | 21 | |
Compositional biasi | 467 – 490 | Basic and acidic residuesSequence analysisAdd BLAST | 24 |
Sequence similaritiesi
Keywords - Domaini
Transmembrane, Transmembrane helixPhylogenomic databases
eggNOGi | KOG0682, Eukaryota |
HOGENOMi | CLU_000445_33_0_1 |
InParanoidi | Q9C0V1 |
OMAi | ITPACGE |
PhylomeDBi | Q9C0V1 |
Family and domain databases
Gene3Di | 1.10.3430.10, 1 hit |
InterProi | View protein in InterPro IPR029020, Ammonium/urea_transptr IPR001905, Ammonium_transpt IPR018047, Ammonium_transpt_CS IPR024041, NH4_transpt_AmtB-like_dom |
PANTHERi | PTHR43029, PTHR43029, 1 hit |
Pfami | View protein in Pfam PF00909, Ammonium_transp, 1 hit |
TIGRFAMsi | TIGR00836, amt, 1 hit |
PROSITEi | View protein in PROSITE PS01219, AMMONIUM_TRANSP, 1 hit |
i Sequence
Sequence statusi: Complete.
Q9C0V1-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MSSTTDATPT PSGVNGGDSM TVNLNQFYNN GDVAWILTST ALVFIMIPGV
60 70 80 90 100
GFFYSGLARR RSAISMLFLS MMSVAIVAFQ WFFWGYSLTF SHEGGPYIGS
110 120 130 140 150
LANFGLRQTL GRPSSGASSV PDILFCVFQG MFAAITPALA IGAAADRGRM
160 170 180 190 200
FPCMVFMFLW TSIVYDPIAF WTWNPNGWLN KLGSYDFAGG SPVHISSGMA
210 220 230 240 250
ALAYSIVIGK RCDHGTTKYR PHNVPHVVLG TVFLWFGWFG FNGGSSAAAN
260 270 280 290 300
MRGVMAVVVT HLAASVGGIV WCVIDFAKNR HWSVVGFCEG AVAGLVAITP
310 320 330 340 350
GSGFVPPWAA VVIGALGAVF CYAATYLKKI IRVDDALDIF AEHGVGGMVG
360 370 380 390 400
NILTALFAAD YIEALDGSGT AYTGGWITHH YIQLGYQLAD TVSCAAYSFA
410 420 430 440 450
VSCALLFVMN YIPGLSLRVS REDEVLGLDK IELGESAYYY KDSTDEPPPI
460 470 480 490
TTSGVQYTSP TVSDSASNEK EQEHRAQNEA QKEEEYRAES EAQAPAI
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | CU329672 Genomic DNA Translation: CAC36934.1 |
RefSeqi | NP_588424.1, NM_001023415.2 |
Genome annotation databases
EnsemblFungii | SPCPB1C11.01.1; SPCPB1C11.01.1:pep; SPCPB1C11.01 |
GeneIDi | 2539332 |
KEGGi | spo:SPCPB1C11.01 |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | CU329672 Genomic DNA Translation: CAC36934.1 |
RefSeqi | NP_588424.1, NM_001023415.2 |
3D structure databases
AlphaFoldDBi | Q9C0V1 |
SMRi | Q9C0V1 |
ModBasei | Search... |
Protein-protein interaction databases
BioGRIDi | 275898, 37 interactors |
STRINGi | 4896.SPCPB1C11.01.1 |
PTM databases
iPTMneti | Q9C0V1 |
Proteomic databases
MaxQBi | Q9C0V1 |
PaxDbi | Q9C0V1 |
Genome annotation databases
EnsemblFungii | SPCPB1C11.01.1; SPCPB1C11.01.1:pep; SPCPB1C11.01 |
GeneIDi | 2539332 |
KEGGi | spo:SPCPB1C11.01 |
Organism-specific databases
PomBasei | SPCPB1C11.01, amt1 |
VEuPathDBi | FungiDB:SPCPB1C11.01 |
Phylogenomic databases
eggNOGi | KOG0682, Eukaryota |
HOGENOMi | CLU_000445_33_0_1 |
InParanoidi | Q9C0V1 |
OMAi | ITPACGE |
PhylomeDBi | Q9C0V1 |
Miscellaneous databases
PROi | PR:Q9C0V1 |
Family and domain databases
Gene3Di | 1.10.3430.10, 1 hit |
InterProi | View protein in InterPro IPR029020, Ammonium/urea_transptr IPR001905, Ammonium_transpt IPR018047, Ammonium_transpt_CS IPR024041, NH4_transpt_AmtB-like_dom |
PANTHERi | PTHR43029, PTHR43029, 1 hit |
Pfami | View protein in Pfam PF00909, Ammonium_transp, 1 hit |
TIGRFAMsi | TIGR00836, amt, 1 hit |
PROSITEi | View protein in PROSITE PS01219, AMMONIUM_TRANSP, 1 hit |
MobiDBi | Search... |
Entry informationi
Entry namei | AMT1_SCHPO | |
Accessioni | Q9C0V1Primary (citable) accession number: Q9C0V1 | |
Entry historyi | Integrated into UniProtKB/Swiss-Prot: | February 20, 2007 |
Last sequence update: | June 1, 2001 | |
Last modified: | May 25, 2022 | |
This is version 114 of the entry and version 1 of the sequence. See complete history. | ||
Entry statusi | Reviewed (UniProtKB/Swiss-Prot) | |
Annotation program | Fungal Protein Annotation Program |
Miscellaneousi
Keywords - Technical termi
Reference proteomeDocuments
- Schizosaccharomyces pombe
Schizosaccharomyces pombe: entries and gene names - SIMILARITY comments
Index of protein domains and families