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Protein

Protein zyg-11 homolog B

Gene

ZYG11B

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score:

Annotation score:3 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the ‘protein existence’ evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Probably acts as target recruitment subunit in the E3 ubiquitin ligase complex ZYG11B-CUL2-Elongin BC.

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

  • ubiquitin-protein transferase activity Source: GO_Central

GO - Biological processi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Biological processUbl conjugation pathway

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Protein zyg-11 homolog B
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: ‘Name’, ‘Synonyms’, ‘Ordered locus names’ and ‘ORF names’.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:ZYG11B
Synonyms:KIAA1730
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiHomo sapiens (Human)
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the ‘taxonomic identifier’ or ‘taxid’.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri9606 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000005640 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes_manual">proteome</a> can consist of several components. <br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 1

Organism-specific databases

Eukaryotic Pathogen Database Resources

More...
EuPathDBi
HostDB:ENSG00000162378.12

Human Gene Nomenclature Database

More...
HGNCi
HGNC:25820 ZYG11B

neXtProt; the human protein knowledge platform

More...
neXtProti
NX_Q9C0D3

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

Mutagenesis

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/manual/pathology_and_biotech_section">'Pathology and Biotech'</a> section describes the effect of the experimental mutation of one or more amino acid(s) on the biological properties of the protein.<p><a href='/help/mutagen' target='_top'>More...</a></p>Mutagenesisi18L → S: Abolishes interaction with TCEB1. 1 Publication1

Organism-specific databases

Open Targets

More...
OpenTargetsi
ENSG00000162378

The Pharmacogenetics and Pharmacogenomics Knowledge Base

More...
PharmGKBi
PA142670468

Polymorphism and mutation databases

BioMuta curated single-nucleotide variation and disease association database

More...
BioMutai
ZYG11B

Domain mapping of disease mutations (DMDM)

More...
DMDMi
158706479

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘PTM / Processing’ section describes the extent of a polypeptide chain in the mature protein following processing.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00003050871 – 744Protein zyg-11 homolog BAdd BLAST744

Proteomic databases

Encyclopedia of Proteome Dynamics

More...
EPDi
Q9C0D3

jPOST - Japan Proteome Standard Repository/Database

More...
jPOSTi
Q9C0D3

MaxQB - The MaxQuant DataBase

More...
MaxQBi
Q9C0D3

PaxDb, a database of protein abundance averages across all three domains of life

More...
PaxDbi
Q9C0D3

PeptideAtlas

More...
PeptideAtlasi
Q9C0D3

PRoteomics IDEntifications database

More...
PRIDEi
Q9C0D3

ProteomicsDB human proteome resource

More...
ProteomicsDBi
80011
80012 [Q9C0D3-2]

PTM databases

iPTMnet integrated resource for PTMs in systems biology context

More...
iPTMneti
Q9C0D3

Comprehensive resource for the study of protein post-translational modifications (PTMs) in human, mouse and rat.

More...
PhosphoSitePlusi
Q9C0D3

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...
Bgeei
ENSG00000162378 Expressed in 208 organ(s), highest expression level in quadriceps femoris

CleanEx database of gene expression profiles

More...
CleanExi
HS_ZYG11B

ExpressionAtlas, Differential and Baseline Expression

More...
ExpressionAtlasi
Q9C0D3 baseline and differential

Genevisible search portal to normalized and curated expression data from Genevestigator

More...
Genevisiblei
Q9C0D3 HS

Organism-specific databases

Human Protein Atlas

More...
HPAi
HPA028156

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

<p>This subsection of the <a href="http://www.uniprot.org/help/interaction_section">'Interaction'</a> section provides information about the protein quaternary structure and interaction(s) with other proteins or protein complexes (with the exception of physiological receptor-ligand interactions which are annotated in the <a href="http://www.uniprot.org/help/function_section">'Function'</a> section).<p><a href='/help/subunit_structure' target='_top'>More...</a></p>Subunit structurei

Interacts with TCEB1/Elongin C. Part of an E3 ubiquitin ligase complex including ZYG11B, CUL2 and Elongin BC.1 Publication

Protein-protein interaction databases

The Biological General Repository for Interaction Datasets (BioGrid)

More...
BioGridi
122820, 51 interactors

Protein interaction database and analysis system

More...
IntActi
Q9C0D3, 5 interactors

Molecular INTeraction database

More...
MINTi
Q9C0D3

STRING: functional protein association networks

More...
STRINGi
9606.ENSP00000294353

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

Protein Model Portal of the PSI-Nature Structural Biology Knowledgebase

More...
ProteinModelPortali
Q9C0D3

SWISS-MODEL Repository - a database of annotated 3D protein structure models

More...
SMRi
Q9C0D3

Database of comparative protein structure models

More...
ModBasei
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Family and Domains’ section indicates the positions and types of repeated sequence motifs or repeated domains within the protein.<p><a href='/help/repeat' target='_top'>More...</a></p>Repeati185 – 208LRR 1Add BLAST24
Repeati216 – 236LRR 2Add BLAST21
Repeati237 – 261LRR 3Add BLAST25

<p>This subsection of the ‘Family and domains’ section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Belongs to the zyg-11 family.Curated

Keywords - Domaini

Leucine-rich repeat, Repeat

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
KOG3665 Eukaryota
ENOG410XPSX LUCA

Ensembl GeneTree

More...
GeneTreei
ENSGT00530000063187

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...
HOGENOMi
HOG000004816

The HOVERGEN Database of Homologous Vertebrate Genes

More...
HOVERGENi
HBG108780

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
Q9C0D3

KEGG Orthology (KO)

More...
KOi
K10350

Identification of Orthologs from Complete Genome Data

More...
OMAi
HVCSKNA

Database of Orthologous Groups

More...
OrthoDBi
374821at2759

Database for complete collections of gene phylogenies

More...
PhylomeDBi
Q9C0D3

TreeFam database of animal gene trees

More...
TreeFami
TF313007

Family and domain databases

Gene3D Structural and Functional Annotation of Protein Families

More...
Gene3Di
1.25.10.10, 1 hit
3.80.10.10, 1 hit

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR011989 ARM-like
IPR016024 ARM-type_fold
IPR001611 Leu-rich_rpt
IPR032675 LRR_dom_sf
IPR040367 ZYG11B

The PANTHER Classification System

More...
PANTHERi
PTHR12904:SF21 PTHR12904:SF21, 1 hit

Superfamily database of structural and functional annotation

More...
SUPFAMi
SSF48371 SSF48371, 1 hit

PROSITE; a protein domain and family database

More...
PROSITEi
View protein in PROSITE
PS51450 LRR, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>.<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequences (2+)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

This entry describes 2 <p>This subsection of the ‘Sequence’ section lists the alternative protein sequences (isoforms) that can be generated from the same gene by a single or by the combination of up to four biological events (alternative promoter usage, alternative splicing, alternative initiation and ribosomal frameshifting). Additionally, this section gives relevant information on each alternative protein isoform.<p><a href='/help/alternative_products' target='_top'>More...</a></p> isoformsi produced by alternative splicing. AlignAdd to basket

This entry has 2 described isoforms and 1 potential isoform that is computationally mapped.Show allAlign All

Isoform 1 (identifier: Q9C0D3-1) [UniParc]FASTAAdd to basket

This isoform has been chosen as the 'canonical' sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

« Hide
        10         20         30         40         50
MPEDQAGAAM EEASPYSLLD ICLNFLTTHL EKFCSARQDG TLCLQEPGVF
60 70 80 90 100
PQEVADRLLR TMAFHGLLND GTVGIFRGNQ MRLKRACIRK AKISAVAFRK
110 120 130 140 150
AFCHHKLVEL DATGVNADIT ITDIISGLGS NKWIQQNLQC LVLNSLTLSL
160 170 180 190 200
EDPYERCFSR LSGLRALSIT NVLFYNEDLA EVASLPRLES LDISNTSITD
210 220 230 240 250
ITALLACKDR LKSLTMHHLK CLKMTTTQIL DVVRELKHLN HLDISDDKQF
260 270 280 290 300
TSDIALRLLE QKDILPNLVS LDVSGRKHVT DKAVEAFIQQ RPSMQFVGLL
310 320 330 340 350
ATDAGYSEFL TGEGHLKVSG EANETQIAEA LKRYSERAFF VREALFHLFS
360 370 380 390 400
LTHVMEKTKP EILKLVVTGM RNHPMNLPVQ LAASACVFNL TKQDLAAGMP
410 420 430 440 450
VRLLADVTHL LLKAMEHFPN HQQLQKNCLL SLCSDRILQD VPFNRFEAAK
460 470 480 490 500
LVMQWLCNHE DQNMQRMAVA IISILAAKLS TEQTAQLGTE LFIVRQLLQI
510 520 530 540 550
VKQKTNQNSV DTTLKFTLSA LWNLTDESPT TCRHFIENQG LELFMRVLES
560 570 580 590 600
FPTESSIQQK VLGLLNNIAE VQELHSELMW KDFIDHISSL LHSVEVEVSY
610 620 630 640 650
FAAGIIAHLI SRGEQAWTLS RSQRNSLLDD LHSAILKWPT PECEMVAYRS
660 670 680 690 700
FNPFFPLLGC FTTPGVQLWA VWAMQHVCSK NPSRYCSMLI EEGGLQHLYN
710 720 730 740
IKDHEHTDPH VQQIAVAILD SLEKHIVRHG RPPPCKKQPQ ARLN
Length:744
Mass (Da):83,921
Last modified:October 2, 2007 - v2
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i0D8C19251CA67573
GO
Isoform 2 (identifier: Q9C0D3-2) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     1-578: Missing.

Note: No experimental confirmation available.
Show »
Length:166
Mass (Da):19,006
Checksum:i0225A6D407596545
GO

<p>In eukaryotic reference proteomes, unreviewed entries that are likely to belong to the same gene are computationally mapped, based on gene identifiers from Ensembl, EnsemblGenomes and model organism databases.<p><a href='/help/gene_centric_isoform_mapping' target='_top'>More...</a></p>Computationally mapped potential isoform sequencesi

There is 1 potential isoform mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
A8DPD7A8DPD7_HUMAN
Protein zyg-11 homolog B
ZYG11B
566Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>

<p>This subsection of the ‘Sequence’ section reports difference(s) between the protein sequence shown in the UniProtKB entry and other available protein sequences derived from the same gene.<p><a href='/help/sequence_caution' target='_top'>More...</a></p>Sequence cautioni

The sequence BAB21821 differs from that shown. Reason: Erroneous initiation.Curated

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Sequence’ section reports difference(s) between the canonical sequence (displayed by default in the entry) and the different sequence submissions merged in the entry. These various submissions may originate from different sequencing projects, different types of experiments, or different biological samples. Sequence conflicts are usually of unknown origin.<p><a href='/help/conflict' target='_top'>More...</a></p>Sequence conflicti672W → C in BAB14596 (PubMed:14702039).Curated1

Alternative sequence

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Sequence’ section describes the sequence of naturally occurring alternative protein isoform(s). The changes in the amino acid sequence may be due to alternative splicing, alternative promoter usage, alternative initiation, or ribosomal frameshifting. The information stored in this subsection is used to automatically construct alternative protein sequence(s) for display.<p><a href='/help/var_seq' target='_top'>More...</a></p>Alternative sequenceiVSP_0282241 – 578Missing in isoform 2. 1 PublicationAdd BLAST578

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

More...
GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
AB051517 mRNA Translation: BAB21821.1 Different initiation.
AK023518 mRNA Translation: BAB14596.1
BC029832 mRNA Translation: AAH29832.2

The Consensus CDS (CCDS) project

More...
CCDSi
CCDS30717.1 [Q9C0D3-1]

NCBI Reference Sequences

More...
RefSeqi
NP_078922.1, NM_024646.2 [Q9C0D3-1]

UniGene gene-oriented nucleotide sequence clusters

More...
UniGenei
Hs.476280

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...
Ensembli
ENST00000294353; ENSP00000294353; ENSG00000162378 [Q9C0D3-1]

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
79699

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
hsa:79699

UCSC genome browser

More...
UCSCi
uc001cuj.4 human [Q9C0D3-1]

Keywords - Coding sequence diversityi

Alternative splicing

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AB051517 mRNA Translation: BAB21821.1 Different initiation.
AK023518 mRNA Translation: BAB14596.1
BC029832 mRNA Translation: AAH29832.2
CCDSiCCDS30717.1 [Q9C0D3-1]
RefSeqiNP_078922.1, NM_024646.2 [Q9C0D3-1]
UniGeneiHs.476280

3D structure databases

ProteinModelPortaliQ9C0D3
SMRiQ9C0D3
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi122820, 51 interactors
IntActiQ9C0D3, 5 interactors
MINTiQ9C0D3
STRINGi9606.ENSP00000294353

PTM databases

iPTMnetiQ9C0D3
PhosphoSitePlusiQ9C0D3

Polymorphism and mutation databases

BioMutaiZYG11B
DMDMi158706479

Proteomic databases

EPDiQ9C0D3
jPOSTiQ9C0D3
MaxQBiQ9C0D3
PaxDbiQ9C0D3
PeptideAtlasiQ9C0D3
PRIDEiQ9C0D3
ProteomicsDBi80011
80012 [Q9C0D3-2]

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENST00000294353; ENSP00000294353; ENSG00000162378 [Q9C0D3-1]
GeneIDi79699
KEGGihsa:79699
UCSCiuc001cuj.4 human [Q9C0D3-1]

Organism-specific databases

Comparative Toxicogenomics Database

More...
CTDi
79699
EuPathDBiHostDB:ENSG00000162378.12

GeneCards: human genes, protein and diseases

More...
GeneCardsi
ZYG11B
HGNCiHGNC:25820 ZYG11B
HPAiHPA028156
neXtProtiNX_Q9C0D3
OpenTargetsiENSG00000162378
PharmGKBiPA142670468

Human Unidentified Gene-Encoded large proteins database

More...
HUGEi
Search...

GenAtlas: human gene database

More...
GenAtlasi
Search...

Phylogenomic databases

eggNOGiKOG3665 Eukaryota
ENOG410XPSX LUCA
GeneTreeiENSGT00530000063187
HOGENOMiHOG000004816
HOVERGENiHBG108780
InParanoidiQ9C0D3
KOiK10350
OMAiHVCSKNA
OrthoDBi374821at2759
PhylomeDBiQ9C0D3
TreeFamiTF313007

Miscellaneous databases

ChiTaRS: a database of human, mouse and fruit fly chimeric transcripts and RNA-sequencing data

More...
ChiTaRSi
ZYG11B human

Database of phenotypes from RNA interference screens in Drosophila and Homo sapiens

More...
GenomeRNAii
79699

Protein Ontology

More...
PROi
PR:Q9C0D3

Gene expression databases

BgeeiENSG00000162378 Expressed in 208 organ(s), highest expression level in quadriceps femoris
CleanExiHS_ZYG11B
ExpressionAtlasiQ9C0D3 baseline and differential
GenevisibleiQ9C0D3 HS

Family and domain databases

Gene3Di1.25.10.10, 1 hit
3.80.10.10, 1 hit
InterProiView protein in InterPro
IPR011989 ARM-like
IPR016024 ARM-type_fold
IPR001611 Leu-rich_rpt
IPR032675 LRR_dom_sf
IPR040367 ZYG11B
PANTHERiPTHR12904:SF21 PTHR12904:SF21, 1 hit
SUPFAMiSSF48371 SSF48371, 1 hit
PROSITEiView protein in PROSITE
PS51450 LRR, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

More...
ProtoNeti
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the ‘Entry information’ section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiZY11B_HUMAN
<p>This subsection of the ‘Entry information’ section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called ‘Primary (citable) accession number’.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q9C0D3
Secondary accession number(s): Q8N2X3, Q9H8L8
<p>This subsection of the ‘Entry information’ section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification (‘Last modified’). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: October 2, 2007
Last sequence update: October 2, 2007
Last modified: January 16, 2019
This is version 124 of the entry and version 2 of the sequence. See complete history.
<p>This subsection of the ‘Entry information’ section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families
  2. Human chromosome 1
    Human chromosome 1: entries, gene names and cross-references to MIM
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