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Entry version 114 (13 Feb 2019)
Sequence version 2 (24 Jan 2006)
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Protein

BMP/retinoic acid-inducible neural-specific protein 2

Gene

BRINP2

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score:

Annotation score:4 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at transcript leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the ‘protein existence’ evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Inhibits neuronal cell proliferation by negative regulation of the cell cycle transition.By similarity

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Biological processi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Biological processCell cycle, Growth arrest

Protein family/group databases

Transport Classification Database

More...
TCDBi
1.C.39.17.2 the membrane attack complex/perforin (macpf) family

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
BMP/retinoic acid-inducible neural-specific protein 2
Alternative name(s):
DBCCR1-like protein 2
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: ‘Name’, ‘Synonyms’, ‘Ordered locus names’ and ‘ORF names’.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:BRINP2
Synonyms:DBCCR1L2, FAM5B, KIAA1747
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiHomo sapiens (Human)
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the ‘taxonomic identifier’ or ‘taxid’.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri9606 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000005640 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes_manual">proteome</a> can consist of several components. <br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 1

Organism-specific databases

Eukaryotic Pathogen Database Resources

More...
EuPathDBi
HostDB:ENSG00000198797.6

Human Gene Nomenclature Database

More...
HGNCi
HGNC:13746 BRINP2

neXtProt; the human protein knowledge platform

More...
neXtProti
NX_Q9C0B6

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte & Seán O’Donoghue; Source: COMPARTMENTS

Keywords - Cellular componenti

Secreted

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

Organism-specific databases

Open Targets

More...
OpenTargetsi
ENSG00000198797

The Pharmacogenetics and Pharmacogenomics Knowledge Base

More...
PharmGKBi
PA142671895

Polymorphism and mutation databases

BioMuta curated single-nucleotide variation and disease association database

More...
BioMutai
BRINP2

Domain mapping of disease mutations (DMDM)

More...
DMDMi
85700961

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘PTM / Processing’ section denotes the presence of an N-terminal signal peptide.<p><a href='/help/signal' target='_top'>More...</a></p>Signal peptidei1 – 33Sequence analysisAdd BLAST33
<p>This subsection of the ‘PTM / Processing’ section describes the extent of a polypeptide chain in the mature protein following processing.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_000004577034 – 783BMP/retinoic acid-inducible neural-specific protein 2Add BLAST750

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/ptm_processing_section">PTM / Processing</a> section specifies the position and type of each covalently attached glycan group (mono-, di-, or polysaccharide).<p><a href='/help/carbohyd' target='_top'>More...</a></p>Glycosylationi185N-linked (GlcNAc...) asparagineSequence analysis1
Glycosylationi354N-linked (GlcNAc...) asparagineSequence analysis1
Glycosylationi473N-linked (GlcNAc...) asparagineSequence analysis1
Glycosylationi579N-linked (GlcNAc...) asparagineSequence analysis1
Glycosylationi626N-linked (GlcNAc...) asparagineSequence analysis1
Glycosylationi658N-linked (GlcNAc...) asparagineSequence analysis1

Keywords - PTMi

Glycoprotein

Proteomic databases

jPOST - Japan Proteome Standard Repository/Database

More...
jPOSTi
Q9C0B6

PaxDb, a database of protein abundance averages across all three domains of life

More...
PaxDbi
Q9C0B6

PeptideAtlas

More...
PeptideAtlasi
Q9C0B6

PRoteomics IDEntifications database

More...
PRIDEi
Q9C0B6

ProteomicsDB human proteome resource

More...
ProteomicsDBi
79991
79992 [Q9C0B6-2]

PTM databases

iPTMnet integrated resource for PTMs in systems biology context

More...
iPTMneti
Q9C0B6

Comprehensive resource for the study of protein post-translational modifications (PTMs) in human, mouse and rat.

More...
PhosphoSitePlusi
Q9C0B6

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...
Bgeei
ENSG00000198797 Expressed in 108 organ(s), highest expression level in right frontal lobe

Genevisible search portal to normalized and curated expression data from Genevestigator

More...
Genevisiblei
Q9C0B6 HS

Organism-specific databases

Human Protein Atlas

More...
HPAi
HPA050681
HPA061920

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

Protein-protein interaction databases

The Biological General Repository for Interaction Datasets (BioGrid)

More...
BioGridi
121768, 6 interactors

Protein interaction database and analysis system

More...
IntActi
Q9C0B6, 1 interactor

Molecular INTeraction database

More...
MINTi
Q9C0B6

STRING: functional protein association networks

More...
STRINGi
9606.ENSP00000354481

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

Protein Model Portal of the PSI-Nature Structural Biology Knowledgebase

More...
ProteinModelPortali
Q9C0B6

SWISS-MODEL Repository - a database of annotated 3D protein structure models

More...
SMRi
Q9C0B6

Database of comparative protein structure models

More...
ModBasei
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family_and_domains_section">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini85 – 281MACPFAdd BLAST197

<p>This subsection of the ‘Family and domains’ section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Belongs to the BRINP family.Curated

Keywords - Domaini

Signal

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
ENOG410IF4X Eukaryota
ENOG410XQ74 LUCA

Ensembl GeneTree

More...
GeneTreei
ENSGT00940000160314

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...
HOGENOMi
HOG000049122

The HOVERGEN Database of Homologous Vertebrate Genes

More...
HOVERGENi
HBG081412

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
Q9C0B6

Identification of Orthologs from Complete Genome Data

More...
OMAi
GNFPDWE

Database of Orthologous Groups

More...
OrthoDBi
157712at2759

Database for complete collections of gene phylogenies

More...
PhylomeDBi
Q9C0B6

TreeFam database of animal gene trees

More...
TreeFami
TF331600

Family and domain databases

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR033237 BRINP
IPR020864 MACPF

The PANTHER Classification System

More...
PANTHERi
PTHR15564 PTHR15564, 1 hit

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF01823 MACPF, 1 hit

Simple Modular Architecture Research Tool; a protein domain database

More...
SMARTi
View protein in SMART
SM00457 MACPF, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>.<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequences (2)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is in its mature form or if it represents the precursor.<p><a href='/help/sequence_processing' target='_top'>More...</a></p>Sequence processingi: The displayed sequence is further processed into a mature form.

This entry describes 2 <p>This subsection of the ‘Sequence’ section lists the alternative protein sequences (isoforms) that can be generated from the same gene by a single or by the combination of up to four biological events (alternative promoter usage, alternative splicing, alternative initiation and ribosomal frameshifting). Additionally, this section gives relevant information on each alternative protein isoform.<p><a href='/help/alternative_products' target='_top'>More...</a></p> isoformsi produced by alternative splicing. AlignAdd to basket
Isoform 1 (identifier: Q9C0B6-1) [UniParc]FASTAAdd to basket

This isoform has been chosen as the 'canonical' sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

« Hide
        10         20         30         40         50
MRWQCGTRFR GLRPAVAPWT ALLALGLPGW VLAVSATAAA VVPEQHASVA
60 70 80 90 100
GQHPLDWLLT DRGPFHRAQE YADFMERYRQ GFTTRYRIYR EFARWKVNNL
110 120 130 140 150
ALERKDFFSL PLPLAPEFIR NIRLLGRRPN LQQVTENLIK KYGTHFLLSA
160 170 180 190 200
TLGGEESLTI FVDKQKLGRK TETTGGASII GGSGNSTAVS LETLHQLAAS
210 220 230 240 250
YFIDRESTLR RLHHIQIATG AIKVTETRTG PLGCSNYDNL DSVSSVLVQS
260 270 280 290 300
PENKVQLLGL QVLLPEYLRE RFVAAALSYI TCSSEGELVC KENDCWCKCS
310 320 330 340 350
PTFPECNCPD ADIQAMEDSL LQIQDSWATH NRQFEESEEF QALLKRLPDD
360 370 380 390 400
RFLNSTAISQ FWAMDTSLQH RYQQLGAGLK VLFKKTHRIL RRLFNLCKRC
410 420 430 440 450
HRQPRFRLPK ERSLSYWWNR IQSLLYCGES TFPGTFLEQS HSCTCPYDQS
460 470 480 490 500
SCQGPIPCAL GEGPACAHCA PDNSTRCGSC NPGYVLAQGL CRPEVAESLE
510 520 530 540 550
NFLGLETDLQ DLELKYLLQK QDSRIEVHSI FISNDMRLGS WFDPSWRKRM
560 570 580 590 600
LLTLKSNKYK PGLVHVMLAL SLQICLTKNS TLEPVMAIYV NPFGGSHSES
610 620 630 640 650
WFMPVNEGSF PDWERTNVDA AAQCQNWTIT LGNRWKTFFE TVHVYLRSRI
660 670 680 690 700
KSLDDSSNET IYYEPLEMTD PSKNLGYMKI NTLQVFGYSL PFDPDAIRDL
710 720 730 740 750
ILQLDYPYTQ GSQDSALLQL IELRDRVNQL SPPGKVRLDL FSCLLRHRLK
760 770 780
LANNEVGRIQ SSLRAFNSKL PNPVEYETGK LCS
Length:783
Mass (Da):89,005
Last modified:January 24, 2006 - v2
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:iB8362095ADC97FCD
GO
Isoform 2 (identifier: Q9C0B6-2) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     1-153: MRWQCGTRFR...THFLLSATLG → MVRAGGRAWQ...VTNTLVLFTI

Note: No experimental confirmation available.
Show »
Length:678
Mass (Da):76,521
Checksum:iF34E4C754AC2612C
GO

<p>This subsection of the ‘Sequence’ section reports difference(s) between the protein sequence shown in the UniProtKB entry and other available protein sequences derived from the same gene.<p><a href='/help/sequence_caution' target='_top'>More...</a></p>Sequence cautioni

The sequence BAB21838 differs from that shown. Reason: Erroneous initiation. Translation N-terminally shortened.Curated

Natural variant

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Sequence’ section describes natural variant(s) of the protein sequence.<p><a href='/help/variant' target='_top'>More...</a></p>Natural variantiVAR_04902271Y → C. Corresponds to variant dbSNP:rs16850984Ensembl.1
Natural variantiVAR_049023390L → V. Corresponds to variant dbSNP:rs3176443Ensembl.1

Alternative sequence

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Sequence’ section describes the sequence of naturally occurring alternative protein isoform(s). The changes in the amino acid sequence may be due to alternative splicing, alternative promoter usage, alternative initiation, or ribosomal frameshifting.<p><a href='/help/var_seq' target='_top'>More...</a></p>Alternative sequenceiVSP_0170261 – 153MRWQC…SATLG → MVRAGGRAWQQGLHSLSAVS ILAKGFMFLLVGDSRAESVT NTLVLFTI in isoform 2. 1 PublicationAdd BLAST153

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

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GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
AB161694 mRNA Translation: BAD34946.1
AB051534 mRNA Translation: BAB21838.1 Different initiation.
AK123336 mRNA Translation: BAC85583.1
AL022143 Genomic DNA No translation available.
BC028036 mRNA Translation: AAH28036.1
AL035289 mRNA Translation: CAA22893.1
AF131833 mRNA Translation: AAD20055.1

The Consensus CDS (CCDS) project

More...
CCDSi
CCDS1320.1 [Q9C0B6-1]

NCBI Reference Sequences

More...
RefSeqi
NP_066988.1, NM_021165.3 [Q9C0B6-1]
XP_005245436.1, XM_005245379.1 [Q9C0B6-1]

UniGene gene-oriented nucleotide sequence clusters

More...
UniGenei
Hs.495918

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...
Ensembli
ENST00000361539; ENSP00000354481; ENSG00000198797 [Q9C0B6-1]

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
57795

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
hsa:57795

UCSC genome browser

More...
UCSCi
uc001glf.3 human [Q9C0B6-1]

Keywords - Coding sequence diversityi

Alternative splicing, Polymorphism

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AB161694 mRNA Translation: BAD34946.1
AB051534 mRNA Translation: BAB21838.1 Different initiation.
AK123336 mRNA Translation: BAC85583.1
AL022143 Genomic DNA No translation available.
BC028036 mRNA Translation: AAH28036.1
AL035289 mRNA Translation: CAA22893.1
AF131833 mRNA Translation: AAD20055.1
CCDSiCCDS1320.1 [Q9C0B6-1]
RefSeqiNP_066988.1, NM_021165.3 [Q9C0B6-1]
XP_005245436.1, XM_005245379.1 [Q9C0B6-1]
UniGeneiHs.495918

3D structure databases

ProteinModelPortaliQ9C0B6
SMRiQ9C0B6
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi121768, 6 interactors
IntActiQ9C0B6, 1 interactor
MINTiQ9C0B6
STRINGi9606.ENSP00000354481

Protein family/group databases

TCDBi1.C.39.17.2 the membrane attack complex/perforin (macpf) family

PTM databases

iPTMnetiQ9C0B6
PhosphoSitePlusiQ9C0B6

Polymorphism and mutation databases

BioMutaiBRINP2
DMDMi85700961

Proteomic databases

jPOSTiQ9C0B6
PaxDbiQ9C0B6
PeptideAtlasiQ9C0B6
PRIDEiQ9C0B6
ProteomicsDBi79991
79992 [Q9C0B6-2]

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENST00000361539; ENSP00000354481; ENSG00000198797 [Q9C0B6-1]
GeneIDi57795
KEGGihsa:57795
UCSCiuc001glf.3 human [Q9C0B6-1]

Organism-specific databases

Comparative Toxicogenomics Database

More...
CTDi
57795
EuPathDBiHostDB:ENSG00000198797.6

GeneCards: human genes, protein and diseases

More...
GeneCardsi
BRINP2

H-Invitational Database, human transcriptome db

More...
H-InvDBi
HIX0001360
HGNCiHGNC:13746 BRINP2
HPAiHPA050681
HPA061920
neXtProtiNX_Q9C0B6
OpenTargetsiENSG00000198797
PharmGKBiPA142671895

Human Unidentified Gene-Encoded large proteins database

More...
HUGEi
Search...

GenAtlas: human gene database

More...
GenAtlasi
Search...

Phylogenomic databases

eggNOGiENOG410IF4X Eukaryota
ENOG410XQ74 LUCA
GeneTreeiENSGT00940000160314
HOGENOMiHOG000049122
HOVERGENiHBG081412
InParanoidiQ9C0B6
OMAiGNFPDWE
OrthoDBi157712at2759
PhylomeDBiQ9C0B6
TreeFamiTF331600

Miscellaneous databases

Database of phenotypes from RNA interference screens in Drosophila and Homo sapiens

More...
GenomeRNAii
57795

Protein Ontology

More...
PROi
PR:Q9C0B6

Gene expression databases

BgeeiENSG00000198797 Expressed in 108 organ(s), highest expression level in right frontal lobe
GenevisibleiQ9C0B6 HS

Family and domain databases

InterProiView protein in InterPro
IPR033237 BRINP
IPR020864 MACPF
PANTHERiPTHR15564 PTHR15564, 1 hit
PfamiView protein in Pfam
PF01823 MACPF, 1 hit
SMARTiView protein in SMART
SM00457 MACPF, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

More...
ProtoNeti
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the ‘Entry information’ section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiBRNP2_HUMAN
<p>This subsection of the ‘Entry information’ section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called ‘Primary (citable) accession number’.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q9C0B6
Secondary accession number(s): O95560
, Q6ZWC1, Q7LCZ9, Q8N360
<p>This subsection of the ‘Entry information’ section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification (‘Last modified’). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: January 24, 2006
Last sequence update: January 24, 2006
Last modified: February 13, 2019
This is version 114 of the entry and version 2 of the sequence. See complete history.
<p>This subsection of the ‘Entry information’ section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families
  2. Human polymorphisms and disease mutations
    Index of human polymorphisms and disease mutations
  3. Human chromosome 1
    Human chromosome 1: entries, gene names and cross-references to MIM
  4. Human entries with polymorphisms or disease mutations
    List of human entries with polymorphisms or disease mutations
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