UniProtKB - Q9C019 (TRI15_HUMAN)

BLAST

>sp|Q9C019|TRI15_HUMAN Tripartite motif-containing protein 15 OS=Homo sapiens OX=9606 GN=TRIM15 PE=1 SV=1
MPATPSLKVVHELPACTLCAGPLEDAVTIPCGHTFCRLCLPALSQMGAQSSGKILLCPLC
QEEEQAETPMAPVPLGPLGETYCEEHGEKIYFFCENDAEFLCVFCREGPTHQAHTVGFLD
EAIQPYRDRLRSRLEALSTERDEIEDVKCQEDQKLQVLLTQIESKKHQVETAFERLQQEL
EQQRCLLLARLRELEQQIWKERDEYITKVSEEVTRLGAQVKELEEKCQQPASELLQDVRV
NQSRCEMKTFVSPEAISPDLVKKIRDFHRKILTLPEMMRMFSENLAHHLEIDSGVITLDP
QTASRSLVLSEDRKSVRYTRQKKSLPDSPLRFDGLPAVLGFPGFSSGRHRWQVDLQLGDG
GGCTVGVAGEGVRRKGEMGLSAEDGVWAVIISHQQCWASTSPGTDLPLSEIPRGVRVALD
YEAGQVTLHNAQTQEPIFTFTASFSGKVFPFFAVWKKGSCLTLKG

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History
Entry version 163 (07 Nov 2018)
Sequence version 1 (01 Jun 2001)
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Protein

Tripartite motif-containing protein 15

Gene

TRIM15

Organism

Homo sapiens (Human)

Status

Reviewed-Annotation score: -Experimental evidence at protein levelⁱ

Functionⁱ

Regions

Feature key	Position(s)	DescriptionActions	Graphical view	Length
Zinc fingerⁱ	16 – 61	RING-typePROSITE-ProRule annotationAdd BLAST		46
Zinc fingerⁱ	78 – 119	B box-typePROSITE-ProRule annotationAdd BLAST		42

GO - Molecular functionⁱ

zinc ion binding Source: InterPro

View the complete GO annotation on QuickGO ...

GO - Biological processⁱ

innate immune response
Source: UniProtKB
Inferred from mutant phenotypeⁱ
- 18248090
mesodermal cell fate determination
Source: ProtInc
Traceable author statementⁱ
- 10207104
negative regulation of intracellular transport of viral material
Source: UniProtKB
Inferred from mutant phenotypeⁱ
- 18248090
negative regulation of viral release from host cell
Source: UniProtKB
Inferred from direct assayⁱ
- 18248090
positive regulation of DNA-binding transcription factor activity
Source: UniProtKB
Inferred from mutant phenotypeⁱ
- 23077300
positive regulation of NF-kappaB transcription factor activity
Source: UniProtKB
Inferred from direct assayⁱ
- 23077300
positive regulation of RIG-I signaling pathway
Source: UniProtKB
Inferred from mutant phenotypeⁱ
- 23077300
positive regulation of type I interferon production
Source: UniProtKB
Inferred from mutant phenotypeⁱ
- 23077300

View the complete GO annotation on QuickGO ...

Keywordsⁱ

Ligand	Metal-binding, Zinc

Ligand

Metal-binding, Zinc

Protein family/group databases

MoonDBⁱ	Q9C019 Predicted

MoonDBⁱ

Q9C019 Predicted

Names & Taxonomyⁱ

Protein namesⁱ	Recommended name: Tripartite motif-containing protein 15 Alternative name(s): RING finger protein 93 Zinc finger protein 178 Zinc finger protein B7
Gene namesⁱ	Name:TRIM15 Synonyms:RNF93, ZNF178, ZNFB7
Organismⁱ	Homo sapiens (Human)
Taxonomic identifierⁱ	9606 [NCBI]
Taxonomic lineageⁱ	cellular organisms › Eukaryota › Opisthokonta › Metazoa › Eumetazoa › Bilateria › Deuterostomia › Chordata › Craniata › Vertebrata › Gnathostomata › Teleostomi › Euteleostomi › Sarcopterygii › Dipnotetrapodomorpha › Tetrapoda › Amniota › Mammalia › Theria › Eutheria › Boreoeutheria › Euarchontoglires › Primates › Haplorrhini › Simiiformes › Catarrhini › Hominoidea › Hominidae › Homininae › Homo
Proteomesⁱ	UP000005640 Componentⁱ: Chromosome 6

Organism-specific databases

EuPathDBⁱ	HostDB:ENSG00000204610.12
Human Gene Nomenclature Database More...HGNCⁱ	HGNC:16284 TRIM15
neXtProtⁱ	NX_Q9C019

Subcellular locationⁱ

GO - Cellular component

Pathology & Biotechⁱ

Organism-specific databases

DisGeNET More...DisGeNETⁱ	89870
Open Targets More...OpenTargetsⁱ	ENSG00000204610
PharmGKBⁱ	PA38114

Polymorphism and mutation databases

BioMutaⁱ	TRIM15
DMDMⁱ	25009482

PTM / Processingⁱ

Molecule processing

Feature key	Position(s)	DescriptionActions	Graphical view	Length
ChainⁱPRO_0000056218	1 – 465	Tripartite motif-containing protein 15Add BLAST		465

Proteomic databases

MaxQB - The MaxQuant DataBase More...MaxQBⁱ	Q9C019
PaxDbⁱ	Q9C019
PeptideAtlas More...PeptideAtlasⁱ	Q9C019
PRIDEⁱ	Q9C019
ProteomicsDBⁱ	79941 79942 [Q9C019-2]

PTM databases

iPTMnetⁱ	Q9C019
PhosphoSitePlusⁱ	Q9C019

Expressionⁱ

Gene expression databases

Bgeeⁱ	ENSG00000204610 Expressed in 81 organ(s), highest expression level in mucosa of transverse colon
CleanExⁱ	HS_TRIM15
ExpressionAtlasⁱ	Q9C019 baseline and differential
Genevisibleⁱ	Q9C019 HS

Organism-specific databases

Human Protein Atlas More...HPAⁱ	HPA047527

HPAⁱ

HPA047527

Interactionⁱ

Binary interactionsⁱ

With	Entry	#Exp.	IntAct
AXIN1	O15169	3	EBI-2342111,EBI-710484
FAM151B	Q6UXP7	3	EBI-2342111,EBI-8456391
FAM161A	Q3B820	3	EBI-2342111,EBI-719941
RABGEF1	Q9UJ41	3	EBI-2342111,EBI-913954

Protein-protein interaction databases

BioGridⁱ	124626, 42 interactors
IntActⁱ	Q9C019, 11 interactors
STRINGⁱ	9606.ENSP00000365884

Structureⁱ

3D structure databases

ProteinModelPortalⁱ	Q9C019
SMRⁱ	Q9C019
ModBaseⁱ	Search...
MobiDBⁱ	Search...

Family & Domainsⁱ

Domains and Repeats

Feature key	Position(s)	DescriptionActions	Graphical view	Length
Domainⁱ	276 – 465	B30.2/SPRYPROSITE-ProRule annotationAdd BLAST		190

Coiled coil

Feature key	Position(s)	DescriptionActions	Graphical view	Length
Coiled coilⁱ	126 – 229	Sequence analysisAdd BLAST		104

Sequence similaritiesⁱ

Belongs to the TRIM/RBCC family.Curated

Zinc finger

Feature key	Position(s)	DescriptionActions	Graphical view	Length
Zinc fingerⁱ	16 – 61	RING-typePROSITE-ProRule annotationAdd BLAST		46
Zinc fingerⁱ	78 – 119	B box-typePROSITE-ProRule annotationAdd BLAST		42

Keywords - Domainⁱ

Coiled coil, Zinc-finger

Phylogenomic databases

eggNOGⁱ	KOG2177 Eukaryota ENOG4111G04 LUCA
Ensembl GeneTree More...GeneTreeⁱ	ENSGT00760000118838
HOGENOMⁱ	HOG000234133
HOVERGENⁱ	HBG001357
InParanoidⁱ	Q9C019
KEGG Orthology (KO) More...KOⁱ	K12005
OMAⁱ	HRWQVEV
Database of Orthologous Groups More...OrthoDBⁱ	EOG091G05W2
PhylomeDBⁱ	Q9C019
TreeFamⁱ	TF342569

Family and domain databases

Conserved Domains Database More...CDDⁱ	cd00021 BBOX, 1 hit
Gene3Dⁱ	3.30.40.10, 1 hit
InterProⁱ	View protein in InterPro IPR001870 B30.2/SPRY IPR003879 Butyrophylin_SPRY IPR013320 ConA-like_dom_sf IPR006574 PRY IPR003877 SPRY_dom IPR000315 Znf_B-box IPR018957 Znf_C3HC4_RING-type IPR001841 Znf_RING IPR013083 Znf_RING/FYVE/PHD IPR017907 Znf_RING_CS
Pfam protein domain database More...Pfamⁱ	View protein in Pfam PF13765 PRY, 1 hit PF00622 SPRY, 1 hit PF00643 zf-B_box, 1 hit PF00097 zf-C3HC4, 1 hit
PRINTSⁱ	PR01407 BUTYPHLNCDUF
SMARTⁱ	View protein in SMART SM00336 BBOX, 1 hit SM00589 PRY, 1 hit SM00184 RING, 1 hit SM00449 SPRY, 1 hit
SUPFAMⁱ	SSF49899 SSF49899, 1 hit
PROSITEⁱ	View protein in PROSITE PS50188 B302_SPRY, 1 hit PS50119 ZF_BBOX, 1 hit PS00518 ZF_RING_1, 1 hit PS50089 ZF_RING_2, 1 hit

Sequences (2+)ⁱ

Sequence statusⁱ: Complete.

This entry describes 2 isoformsⁱ produced by alternative splicing. Align Add to basket

This entry has 2 described isoforms and 4 potential isoforms that are computationally mapped.Show all Align All

Isoform 1 (identifier: Q9C019-1) [UniParc]FASTA Add to basket

Also known as: Alpha

This isoform has been chosen as the 'canonical' sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

« Hide

        10         20         30         40         50
MPATPSLKVV HELPACTLCA GPLEDAVTIP CGHTFCRLCL PALSQMGAQS 
        60         70         80         90        100
SGKILLCPLC QEEEQAETPM APVPLGPLGE TYCEEHGEKI YFFCENDAEF 
       110        120        130        140        150
LCVFCREGPT HQAHTVGFLD EAIQPYRDRL RSRLEALSTE RDEIEDVKCQ 
       160        170        180        190        200
EDQKLQVLLT QIESKKHQVE TAFERLQQEL EQQRCLLLAR LRELEQQIWK 
       210        220        230        240        250
ERDEYITKVS EEVTRLGAQV KELEEKCQQP ASELLQDVRV NQSRCEMKTF 
       260        270        280        290        300
VSPEAISPDL VKKIRDFHRK ILTLPEMMRM FSENLAHHLE IDSGVITLDP 
       310        320        330        340        350
QTASRSLVLS EDRKSVRYTR QKKSLPDSPL RFDGLPAVLG FPGFSSGRHR 
       360        370        380        390        400
WQVDLQLGDG GGCTVGVAGE GVRRKGEMGL SAEDGVWAVI ISHQQCWAST 
       410        420        430        440        450
SPGTDLPLSE IPRGVRVALD YEAGQVTLHN AQTQEPIFTF TASFSGKVFP 
       460 
FFAVWKKGSC LTLKG

Length:465

Mass (Da):52,113

Last modified:June 1, 2001 - v1

Checksum:ⁱ303B8BF8623CB00A

Isoform 2 (identifier: Q9C019-2) [UniParc]FASTA Add to basket

Also known as: Beta

The sequence of this isoform differs from the canonical sequence as follows:
103-115: VFCREGPTHQAHT → TSECRTTDGFGCA
116-465: Missing.

« Hide

        10         20         30         40         50
MPATPSLKVV HELPACTLCA GPLEDAVTIP CGHTFCRLCL PALSQMGAQS 
        60         70         80         90        100
SGKILLCPLC QEEEQAETPM APVPLGPLGE TYCEEHGEKI YFFCENDAEF 
       110 
LCTSECRTTD GFGCA

Show »

Length:115

Mass (Da):12,315

Checksum:ⁱ797B6EAA4B95283E

Computationally mapped potential isoform sequencesⁱ

There are 4 potential isoforms mapped to this entry.BLAST Align Show all Add to basket

Entry	Entry name	Protein names	Gene names	Length	Annotation

A0A087X199	A0A087X199_HUMAN	Tripartite motif-containing protein... Tripartite motif-containing protein 15	TRIM15	396	Annotation score:
A0A0G2JJP1	A0A0G2JJP1_HUMAN	TRIM15 TRIM15 (Tripartite motif-containing protein 15)	TRIM15	465	Annotation score:
A0A0G2JL27	A0A0G2JL27_HUMAN	Tripartite motif-containing protein... Tripartite motif-containing protein 15	TRIM15	396	Annotation score:
H0Y5R0	H0Y5R0_HUMAN	Tripartite motif-containing protein... Tripartite motif-containing protein 15	TRIM15	164	Annotation score:

Natural variant

Feature key	Position(s)	DescriptionActions	Length
Natural variantⁱVAR_014228	29	I → V3 PublicationsCorresponds to variant dbSNP:rs17194460Ensembl.	1
Natural variantⁱVAR_052129	42	A → T. Corresponds to variant dbSNP:rs17194467Ensembl.	1
Natural variantⁱVAR_052130	84	E → Q. Corresponds to variant dbSNP:rs17194474Ensembl.	1
Natural variantⁱVAR_052131	235	L → V. Corresponds to variant dbSNP:rs34823152Ensembl.	1
Natural variantⁱVAR_052132	324	S → N2 PublicationsCorresponds to variant dbSNP:rs929156Ensembl.	1

Alternative sequence

Feature key	Position(s)	DescriptionActions	Graphical view	Length
Alternative sequenceⁱVSP_005760	103 – 115	VFCRE…HQAHT → TSECRTTDGFGCA in isoform 2. 1 PublicationAdd BLAST		13
Alternative sequenceⁱVSP_005761	116 – 465	Missing in isoform 2. 1 PublicationAdd BLAST		350

Sequence databases

Select the link destinations: EMBLⁱ GenBankⁱ DDBJⁱ Links Updated	AF220132 mRNA Translation: AAG53505.1 AF220133 mRNA Translation: AAG53506.1 U34249 mRNA Translation: AAD03787.1 BA000025 Genomic DNA Translation: BAB63331.1 AB088089 Genomic DNA Translation: BAC54922.1 BX248419 Genomic DNA No translation available. BX005441 Genomic DNA No translation available. CR759838 Genomic DNA No translation available. BC038585 mRNA Translation: AAH38585.1
The Consensus CDS (CCDS) project More...CCDSⁱ	CCDS4677.1 [Q9C019-1]
NCBI Reference Sequences More...RefSeqⁱ	NP_150232.2, NM_033229.2 [Q9C019-1]
UniGeneⁱ	Hs.591789 Hs.606488

Genome annotation databases

Ensemblⁱ	ENST00000259930; ENSP00000259930; ENSG00000137384 [Q9C019-1] ENST00000376688; ENSP00000365878; ENSG00000204610 [Q9C019-2] ENST00000376694; ENSP00000365884; ENSG00000204610 [Q9C019-1] ENST00000414873; ENSP00000415480; ENSG00000235259 [Q9C019-1] ENST00000421984; ENSP00000413961; ENSG00000227147 [Q9C019-1] ENST00000427091; ENSP00000411683; ENSG00000235960 [Q9C019-1] ENST00000431059; ENSP00000403221; ENSG00000233599 [Q9C019-1] ENST00000550400; ENSP00000447500; ENSG00000233599 [Q9C019-2] ENST00000552676; ENSP00000449686; ENSG00000235905 [Q9C019-2] ENST00000552836; ENSP00000449617; ENSG00000224145 [Q9C019-2]
GeneIDⁱ	89870
KEGGⁱ	hsa:89870
UCSC genome browser More...UCSCⁱ	uc010jrx.4 human [Q9C019-1]

Keywords - Coding sequence diversityⁱ

Alternative splicing, Polymorphism

Protein	Similar proteins		Species	Score	Length	Source
Q9C019	TRIM15		HUMAN		465	UniRef100_Q9C019

Protein	Similar proteins		Species	Score	Length	Source
Q9C019	Tripartite motif-containing protein 15		MACMU		465	UniRef90_Q9C019
Tripartite motif-containing protein 15		PANTR		465
TRIM15		HUMAN		465
Uncharacterized protein		PANPA		465
Uncharacterized protein		MANLE		465
+52
Q9C019-2	TRIM15 isoform 3		PANTR		115	UniRef90_Q9C019-2
TRIM15 isoform 3		PONAB		115
Uncharacterized protein		RHIRO		115
Uncharacterized protein		PAPAN		115
Tripartite motif-containing protein 15		MACMU		112

Protein	Similar proteins		Species	Score	Length	Source
Q9C019	Tripartite motif-containing protein 15		MACMU		465	UniRef50_Q9C019
Tripartite motif-containing protein 15		PANTR		465
TRIM15		HUMAN		465
Uncharacterized protein		RHIBE		465
TRIM15 isoform 1		PONAB		465
+69
Q9C019-2	Uncharacterized protein		PAPAN		115	UniRef50_Q9C019-2
TRIM15 isoform 3		PANTR		115
Uncharacterized protein		RHIRO		115
TRIM15 isoform 3		PONAB		115
Tripartite motif-containing protein 15		MACMU		112
+2

Cross-referencesⁱ

Sequence databases

Select the link destinations: EMBLⁱ GenBankⁱ DDBJⁱ Links Updated	AF220132 mRNA Translation: AAG53505.1 AF220133 mRNA Translation: AAG53506.1 U34249 mRNA Translation: AAD03787.1 BA000025 Genomic DNA Translation: BAB63331.1 AB088089 Genomic DNA Translation: BAC54922.1 BX248419 Genomic DNA No translation available. BX005441 Genomic DNA No translation available. CR759838 Genomic DNA No translation available. BC038585 mRNA Translation: AAH38585.1
CCDSⁱ	CCDS4677.1 [Q9C019-1]
RefSeqⁱ	NP_150232.2, NM_033229.2 [Q9C019-1]
UniGeneⁱ	Hs.591789 Hs.606488

3D structure databases

ProteinModelPortalⁱ	Q9C019
SMRⁱ	Q9C019
ModBaseⁱ	Search...
MobiDBⁱ	Search...

Protein-protein interaction databases

BioGridⁱ	124626, 42 interactors
IntActⁱ	Q9C019, 11 interactors
STRINGⁱ	9606.ENSP00000365884

Protein family/group databases

MoonDBⁱ	Q9C019 Predicted

MoonDBⁱ

Q9C019 Predicted

PTM databases

iPTMnetⁱ	Q9C019
PhosphoSitePlusⁱ	Q9C019

Polymorphism and mutation databases

BioMutaⁱ	TRIM15
DMDMⁱ	25009482

Proteomic databases

MaxQBⁱ	Q9C019
PaxDbⁱ	Q9C019
PeptideAtlasⁱ	Q9C019
PRIDEⁱ	Q9C019
ProteomicsDBⁱ	79941 79942 [Q9C019-2]

Protocols and materials databases

The DNASU plasmid repository More...DNASUⁱ	89870
Structural Biology Knowledgebase	Search...

Genome annotation databases

Organism-specific databases

CTDⁱ	89870
DisGeNETⁱ	89870
EuPathDBⁱ	HostDB:ENSG00000204610.12
GeneCardsⁱ	TRIM15
HGNCⁱ	HGNC:16284 TRIM15
HPAⁱ	HPA047527
neXtProtⁱ	NX_Q9C019
OpenTargetsⁱ	ENSG00000204610
PharmGKBⁱ	PA38114
GenAtlas: human gene database More...GenAtlasⁱ	Search...

Phylogenomic databases

eggNOGⁱ	KOG2177 Eukaryota ENOG4111G04 LUCA
GeneTreeⁱ	ENSGT00760000118838
HOGENOMⁱ	HOG000234133
HOVERGENⁱ	HBG001357
InParanoidⁱ	Q9C019
KOⁱ	K12005
OMAⁱ	HRWQVEV
OrthoDBⁱ	EOG091G05W2
PhylomeDBⁱ	Q9C019
TreeFamⁱ	TF342569

Miscellaneous databases

ChiTaRSⁱ	TRIM15 human
GeneWikiⁱ	TRIM15
GenomeRNAiⁱ	89870
Protein Ontology More...PROⁱ	PR:Q9C019

Gene expression databases

Bgeeⁱ	ENSG00000204610 Expressed in 81 organ(s), highest expression level in mucosa of transverse colon
CleanExⁱ	HS_TRIM15
ExpressionAtlasⁱ	Q9C019 baseline and differential
Genevisibleⁱ	Q9C019 HS

Family and domain databases

CDDⁱ	cd00021 BBOX, 1 hit
Gene3Dⁱ	3.30.40.10, 1 hit
InterProⁱ	View protein in InterPro IPR001870 B30.2/SPRY IPR003879 Butyrophylin_SPRY IPR013320 ConA-like_dom_sf IPR006574 PRY IPR003877 SPRY_dom IPR000315 Znf_B-box IPR018957 Znf_C3HC4_RING-type IPR001841 Znf_RING IPR013083 Znf_RING/FYVE/PHD IPR017907 Znf_RING_CS
Pfamⁱ	View protein in Pfam PF13765 PRY, 1 hit PF00622 SPRY, 1 hit PF00643 zf-B_box, 1 hit PF00097 zf-C3HC4, 1 hit
PRINTSⁱ	PR01407 BUTYPHLNCDUF
SMARTⁱ	View protein in SMART SM00336 BBOX, 1 hit SM00589 PRY, 1 hit SM00184 RING, 1 hit SM00449 SPRY, 1 hit
SUPFAMⁱ	SSF49899 SSF49899, 1 hit
PROSITEⁱ	View protein in PROSITE PS50188 B302_SPRY, 1 hit PS50119 ZF_BBOX, 1 hit PS00518 ZF_RING_1, 1 hit PS50089 ZF_RING_2, 1 hit
ProtoNetⁱ	Search...

Entry informationⁱ

Entry nameⁱ	TRI15_HUMAN
Accessionⁱ	Q9C019Primary (citable) accession number: Q9C019 Secondary accession number(s): A2BEC9 , O95604, Q8IUX9, Q9C018
Entry historyⁱ	Integrated into UniProtKB/Swiss-Prot:	November 8, 2002
	Last sequence update:	June 1, 2001
	Last modified:	November 7, 2018
	This is version 163 of the entry and version 1 of the sequence. See complete history.
Entry statusⁱ	Reviewed (UniProtKB/Swiss-Prot)
Annotation program	Chordata Protein Annotation Program
Disclaimer	Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousⁱ

Keywords - Technical termⁱ

Complete proteome, Reference proteome

Documents

SIMILARITY comments
Index of protein domains and families
Human entries with polymorphisms or disease mutations
List of human entries with polymorphisms or disease mutations
Human polymorphisms and disease mutations
Index of human polymorphisms and disease mutations
Human chromosome 6
Human chromosome 6: entries, gene names and cross-references to MIM

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UniProtKB - Q9C019 (TRI15_HUMAN)

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Tripartite motif-containing protein 15

TRIM15

Select a section on the left to see content.

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Regions

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

GO - Biological processi

Protein family/group databases

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

Organism-specific databases

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Other locations

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

Organism-specific databases

Polymorphism and mutation databases

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Proteomic databases

PTM databases

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

Organism-specific databases

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

Protein-protein interaction databases

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Coiled coil

<p>This subsection of the ‘Family and domains’ section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Zinc finger

Keywords - Domaini

Phylogenomic databases

Family and domain databases

Natural variant

Alternative sequence

Sequence databases

Genome annotation databases

Keywords - Coding sequence diversityi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

3D structure databases

Protein-protein interaction databases

Protein family/group databases

PTM databases

Polymorphism and mutation databases

Proteomic databases

Protocols and materials databases

Genome annotation databases

Organism-specific databases

Phylogenomic databases

Miscellaneous databases

Gene expression databases

Family and domain databases

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Documents

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Functionⁱ

GO - Molecular functionⁱ

GO - Biological processⁱ

Names & Taxonomyⁱ

Subcellular locationⁱ

Pathology & Biotechⁱ

PTM / Processingⁱ

Expressionⁱ

Interactionⁱ

Structureⁱ

Family & Domainsⁱ

Sequence similaritiesⁱ

Keywords - Domainⁱ

Keywords - Coding sequence diversityⁱ

Cross-referencesⁱ

Entry informationⁱ

Miscellaneousⁱ

Keywords - Technical termⁱ