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Entry version 127 (18 Sep 2019)
Sequence version 1 (01 Jun 2001)
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Protein

cAMP-dependent protein kinase inhibitor beta

Gene

PKIB

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score:

Annotation score:3 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Protein inferred from homologyi <p>This indicates the type of evidence that supports the existence of the protein. Note that the ‘protein existence’ evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Extremely potent competitive inhibitor of cAMP-dependent protein kinase activity, this protein interacts with the catalytic subunit of the enzyme after the cAMP-induced dissociation of its regulatory chains.By similarity

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection describes interesting single amino acid sites on the sequence that are not defined in any other subsection. This subsection can be displayed in different sections (‘Function’, ‘PTM / Processing’, ‘Pathology and Biotech’) according to its content.<p><a href='/help/site' target='_top'>More...</a></p>Sitei23Important for inhibitionBy similarity1
Sitei26Important for inhibitionBy similarity1
Sitei27Important for inhibitionBy similarity1

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

GO - Biological processi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Molecular functionProtein kinase inhibitor

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
cAMP-dependent protein kinase inhibitor beta
Short name:
PKI-beta
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: ‘Name’, ‘Synonyms’, ‘Ordered locus names’ and ‘ORF names’.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:PKIB
Synonyms:PRKACN2
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiHomo sapiens (Human)
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the ‘taxonomic identifier’ or ‘taxid’.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri9606 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000005640 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes_manual">proteome</a> can consist of several components. <br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 6

Organism-specific databases

Human Gene Nomenclature Database

More...
HGNCi
HGNC:9018 PKIB

Online Mendelian Inheritance in Man (OMIM)

More...
MIMi
606914 gene

neXtProt; the human protein knowledge platform

More...
neXtProti
NX_Q9C010

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte & Seán O’Donoghue; Source: COMPARTMENTS

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

Organism-specific databases

DisGeNET

More...
DisGeNETi
5570

Open Targets

More...
OpenTargetsi
ENSG00000135549

The Pharmacogenetics and Pharmacogenomics Knowledge Base

More...
PharmGKBi
PA33350

Miscellaneous databases

Pharos NIH Druggable Genome Knowledgebase

More...
Pharosi
Q9C010

Polymorphism and mutation databases

BioMuta curated single-nucleotide variation and disease association database

More...
BioMutai
PKIB

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘PTM / Processing’ section describes the extent of a polypeptide chain in the mature protein following processing.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00001545381 – 78cAMP-dependent protein kinase inhibitor betaAdd BLAST78

Proteomic databases

Encyclopedia of Proteome Dynamics

More...
EPDi
Q9C010

jPOST - Japan Proteome Standard Repository/Database

More...
jPOSTi
Q9C010

MassIVE - Mass Spectrometry Interactive Virtual Environment

More...
MassIVEi
Q9C010

MaxQB - The MaxQuant DataBase

More...
MaxQBi
Q9C010

PaxDb, a database of protein abundance averages across all three domains of life

More...
PaxDbi
Q9C010

PeptideAtlas

More...
PeptideAtlasi
Q9C010

PRoteomics IDEntifications database

More...
PRIDEi
Q9C010

ProteomicsDB: a multi-organism proteome resource

More...
ProteomicsDBi
79940 [Q9C010-1]

PTM databases

iPTMnet integrated resource for PTMs in systems biology context

More...
iPTMneti
Q9C010

Comprehensive resource for the study of protein post-translational modifications (PTMs) in human, mouse and rat.

More...
PhosphoSitePlusi
Q9C010

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...
Bgeei
ENSG00000135549 Expressed in 160 organ(s), highest expression level in cerebellar vermis

ExpressionAtlas, Differential and Baseline Expression

More...
ExpressionAtlasi
Q9C010 baseline and differential

Genevisible search portal to normalized and curated expression data from Genevestigator

More...
Genevisiblei
Q9C010 HS

Organism-specific databases

Human Protein Atlas

More...
HPAi
HPA030156

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

Protein-protein interaction databases

The Biological General Repository for Interaction Datasets (BioGrid)

More...
BioGridi
111557, 5 interactors

Protein interaction database and analysis system

More...
IntActi
Q9C010, 5 interactors

STRING: functional protein association networks

More...
STRINGi
9606.ENSP00000480824

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

SWISS-MODEL Repository - a database of annotated 3D protein structure models

More...
SMRi
Q9C010

Database of comparative protein structure models

More...
ModBasei
Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

<p>This subsection of the ‘Family and domains’ section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Belongs to the PKI family.Curated

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
ENOG410JF7B Eukaryota
ENOG410Y067 LUCA

Ensembl GeneTree

More...
GeneTreei
ENSGT00530000064264

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...
HOGENOMi
HOG000059641

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
Q9C010

Database of Orthologous Groups

More...
OrthoDBi
1648219at2759

Database for complete collections of gene phylogenies

More...
PhylomeDBi
Q9C010

TreeFam database of animal gene trees

More...
TreeFami
TF330809

Family and domain databases

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR004171 cAMP_dep_PKI

The PANTHER Classification System

More...
PANTHERi
PTHR15416 PTHR15416, 1 hit

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF02827 PKI, 1 hit

PIRSF; a whole-protein classification database

More...
PIRSFi
PIRSF001667 PKI, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequences (2+)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

This entry describes 2 <p>This subsection of the ‘Sequence’ section lists the alternative protein sequences (isoforms) that can be generated from the same gene by a single or by the combination of up to four biological events (alternative promoter usage, alternative splicing, alternative initiation and ribosomal frameshifting). Additionally, this section gives relevant information on each alternative protein isoform.<p><a href='/help/alternative_products' target='_top'>More...</a></p> isoformsi produced by alternative splicing. AlignAdd to basket

This entry has 2 described isoforms and 1 potential isoform that is computationally mapped.Show allAlign All

Isoform 1 (identifier: Q9C010-1) [UniParc]FASTAAdd to basket

This isoform has been chosen as the <div> <p><b>What is the canonical sequence?</b><p><a href='/help/canonical_and_isoforms' target='_top'>More...</a></p>canonicali sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

« Hide
        10         20         30         40         50
MRTDSSKMTD VESGVANFAS SARAGRRNAL PDIQSSAATD GTSDLPLKLE
60 70
ALSVKEDAKE KDEKTTQDQL EKPQNEEK
Length:78
Mass (Da):8,468
Last modified:June 1, 2001 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:iCA4AE267B9ECCD81
GO
Isoform 2 (identifier: Q9C010-2) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     1-1: M → MSHQDVAM

Note: Gene prediction based on EST data.
Show »
Length:85
Mass (Da):9,237
Checksum:iA05D93A815C69A40
GO

<p>In eukaryotic reference proteomes, unreviewed entries that are likely to belong to the same gene are computationally mapped, based on gene identifiers from Ensembl, EnsemblGenomes and model organism databases.<p><a href='/help/gene_centric_isoform_mapping' target='_top'>More...</a></p>Computationally mapped potential isoform sequencesi

There is 1 potential isoform mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
Q5T0Z6Q5T0Z6_HUMAN
cAMP-dependent protein kinase inhib...
PKIB
87Annotation score:

Annotation score:2 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>

Alternative sequence

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Sequence’ section describes the sequence of naturally occurring alternative protein isoform(s). The changes in the amino acid sequence may be due to alternative splicing, alternative promoter usage, alternative initiation, or ribosomal frameshifting.<p><a href='/help/var_seq' target='_top'>More...</a></p>Alternative sequenceiVSP_0469221M → MSHQDVAM in isoform 2. Curated1

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

More...
GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
AF225513 mRNA Translation: AAK00638.1
AK315151 mRNA Translation: BAG37599.1
AF087873 mRNA Translation: AAM10501.1
AL512283 Genomic DNA No translation available.
AL513481 Genomic DNA No translation available.
Z99129 Genomic DNA No translation available.
CH471051 Genomic DNA Translation: EAW48171.1
BC036011 mRNA Translation: AAH36011.1
BC093027 mRNA Translation: AAH93027.1

The Consensus CDS (CCDS) project

More...
CCDSi
CCDS5126.1 [Q9C010-1]
CCDS59033.1 [Q9C010-2]

NCBI Reference Sequences

More...
RefSeqi
NP_001257322.1, NM_001270393.1 [Q9C010-1]
NP_001257323.1, NM_001270394.1 [Q9C010-2]
NP_001257324.1, NM_001270395.1 [Q9C010-2]
NP_115860.1, NM_032471.5 [Q9C010-1]
NP_861459.1, NM_181794.2 [Q9C010-1]
NP_861460.1, NM_181795.2 [Q9C010-1]
XP_011534232.1, XM_011535930.2 [Q9C010-2]
XP_011534233.1, XM_011535931.2 [Q9C010-2]
XP_011534234.1, XM_011535932.2 [Q9C010-2]
XP_011534235.1, XM_011535933.2 [Q9C010-2]
XP_011534236.1, XM_011535934.2
XP_011534237.1, XM_011535935.2 [Q9C010-1]
XP_011534238.1, XM_011535936.1 [Q9C010-1]
XP_011534239.1, XM_011535937.2 [Q9C010-1]

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...
Ensembli
ENST00000258014; ENSP00000258014; ENSG00000135549 [Q9C010-2]
ENST00000354275; ENSP00000346227; ENSG00000135549 [Q9C010-1]
ENST00000368448; ENSP00000357433; ENSG00000135549 [Q9C010-1]
ENST00000368452; ENSP00000357437; ENSG00000135549 [Q9C010-1]
ENST00000392490; ENSP00000376280; ENSG00000135549 [Q9C010-1]
ENST00000392491; ENSP00000376281; ENSG00000135549 [Q9C010-1]
ENST00000615438; ENSP00000480824; ENSG00000135549 [Q9C010-2]

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
5570

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
hsa:5570

UCSC genome browser

More...
UCSCi
uc003pyz.4 human [Q9C010-1]

Keywords - Coding sequence diversityi

Alternative splicing

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF225513 mRNA Translation: AAK00638.1
AK315151 mRNA Translation: BAG37599.1
AF087873 mRNA Translation: AAM10501.1
AL512283 Genomic DNA No translation available.
AL513481 Genomic DNA No translation available.
Z99129 Genomic DNA No translation available.
CH471051 Genomic DNA Translation: EAW48171.1
BC036011 mRNA Translation: AAH36011.1
BC093027 mRNA Translation: AAH93027.1
CCDSiCCDS5126.1 [Q9C010-1]
CCDS59033.1 [Q9C010-2]
RefSeqiNP_001257322.1, NM_001270393.1 [Q9C010-1]
NP_001257323.1, NM_001270394.1 [Q9C010-2]
NP_001257324.1, NM_001270395.1 [Q9C010-2]
NP_115860.1, NM_032471.5 [Q9C010-1]
NP_861459.1, NM_181794.2 [Q9C010-1]
NP_861460.1, NM_181795.2 [Q9C010-1]
XP_011534232.1, XM_011535930.2 [Q9C010-2]
XP_011534233.1, XM_011535931.2 [Q9C010-2]
XP_011534234.1, XM_011535932.2 [Q9C010-2]
XP_011534235.1, XM_011535933.2 [Q9C010-2]
XP_011534236.1, XM_011535934.2
XP_011534237.1, XM_011535935.2 [Q9C010-1]
XP_011534238.1, XM_011535936.1 [Q9C010-1]
XP_011534239.1, XM_011535937.2 [Q9C010-1]

3D structure databases

SMRiQ9C010
ModBaseiSearch...

Protein-protein interaction databases

BioGridi111557, 5 interactors
IntActiQ9C010, 5 interactors
STRINGi9606.ENSP00000480824

PTM databases

iPTMnetiQ9C010
PhosphoSitePlusiQ9C010

Polymorphism and mutation databases

BioMutaiPKIB

Proteomic databases

EPDiQ9C010
jPOSTiQ9C010
MassIVEiQ9C010
MaxQBiQ9C010
PaxDbiQ9C010
PeptideAtlasiQ9C010
PRIDEiQ9C010
ProteomicsDBi79940 [Q9C010-1]

Protocols and materials databases

The DNASU plasmid repository

More...
DNASUi
5570

Genome annotation databases

EnsembliENST00000258014; ENSP00000258014; ENSG00000135549 [Q9C010-2]
ENST00000354275; ENSP00000346227; ENSG00000135549 [Q9C010-1]
ENST00000368448; ENSP00000357433; ENSG00000135549 [Q9C010-1]
ENST00000368452; ENSP00000357437; ENSG00000135549 [Q9C010-1]
ENST00000392490; ENSP00000376280; ENSG00000135549 [Q9C010-1]
ENST00000392491; ENSP00000376281; ENSG00000135549 [Q9C010-1]
ENST00000615438; ENSP00000480824; ENSG00000135549 [Q9C010-2]
GeneIDi5570
KEGGihsa:5570
UCSCiuc003pyz.4 human [Q9C010-1]

Organism-specific databases

Comparative Toxicogenomics Database

More...
CTDi
5570
DisGeNETi5570

GeneCards: human genes, protein and diseases

More...
GeneCardsi
PKIB
HGNCiHGNC:9018 PKIB
HPAiHPA030156
MIMi606914 gene
neXtProtiNX_Q9C010
OpenTargetsiENSG00000135549
PharmGKBiPA33350

GenAtlas: human gene database

More...
GenAtlasi
Search...

Phylogenomic databases

eggNOGiENOG410JF7B Eukaryota
ENOG410Y067 LUCA
GeneTreeiENSGT00530000064264
HOGENOMiHOG000059641
InParanoidiQ9C010
OrthoDBi1648219at2759
PhylomeDBiQ9C010
TreeFamiTF330809

Miscellaneous databases

ChiTaRS: a database of human, mouse and fruit fly chimeric transcripts and RNA-sequencing data

More...
ChiTaRSi
PKIB human

The Gene Wiki collection of pages on human genes and proteins

More...
GeneWikii
PKIB

Database of phenotypes from RNA interference screens in Drosophila and Homo sapiens

More...
GenomeRNAii
5570
PharosiQ9C010

Protein Ontology

More...
PROi
PR:Q9C010

The Stanford Online Universal Resource for Clones and ESTs

More...
SOURCEi
Search...

Gene expression databases

BgeeiENSG00000135549 Expressed in 160 organ(s), highest expression level in cerebellar vermis
ExpressionAtlasiQ9C010 baseline and differential
GenevisibleiQ9C010 HS

Family and domain databases

InterProiView protein in InterPro
IPR004171 cAMP_dep_PKI
PANTHERiPTHR15416 PTHR15416, 1 hit
PfamiView protein in Pfam
PF02827 PKI, 1 hit
PIRSFiPIRSF001667 PKI, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

More...
ProtoNeti
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the ‘Entry information’ section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiIPKB_HUMAN
<p>This subsection of the ‘Entry information’ section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called ‘Primary (citable) accession number’.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q9C010
Secondary accession number(s): B2RCK2, Q567T9, Q5T0Z7
<p>This subsection of the ‘Entry information’ section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification (‘Last modified’). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: September 26, 2001
Last sequence update: June 1, 2001
Last modified: September 18, 2019
This is version 127 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the ‘Entry information’ section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Human chromosome 6
    Human chromosome 6: entries, gene names and cross-references to MIM
  2. SIMILARITY comments
    Index of protein domains and families
  3. MIM cross-references
    Online Mendelian Inheritance in Man (MIM) cross-references in UniProtKB/Swiss-Prot
UniProt is an ELIXIR core data resource
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