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Entry version 121 (11 Dec 2019)
Sequence version 2 (14 Oct 2008)
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Protein

Transmembrane 6 superfamily member 1

Gene

TM6SF1

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score:

Annotation score:3 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the ‘protein existence’ evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

May function as sterol isomerase.1 Publication

Protein family/group databases

Transport Classification Database

More...
TCDBi
8.A.93.2.4 the sigma2 receptor or tmem97 (s2r) family

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Transmembrane 6 superfamily member 1
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: ‘Name’, ‘Synonyms’, ‘Ordered locus names’ and ‘ORF names’.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:TM6SF1
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiHomo sapiens (Human)
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the ‘taxonomic identifier’ or ‘taxid’.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri9606 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000005640 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes_manual">proteome</a> can consist of several components. <br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 15

Organism-specific databases

Eukaryotic Pathogen Database Resources

More...
EuPathDBi
HostDB:ENSG00000136404.15

Human Gene Nomenclature Database

More...
HGNCi
HGNC:11860 TM6SF1

Online Mendelian Inheritance in Man (OMIM)

More...
MIMi
606562 gene

neXtProt; the human protein knowledge platform

More...
neXtProti
NX_Q9BZW5

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte & Seán O’Donoghue; Source: COMPARTMENTS

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/subcellular_location_section">'Subcellular location'</a> section describes the extent of a membrane-spanning region of the protein. It denotes the presence of both alpha-helical transmembrane regions and the membrane spanning regions of beta-barrel transmembrane proteins.<p><a href='/help/transmem' target='_top'>More...</a></p>Transmembranei3 – 23Helical; Name=1Sequence analysisAdd BLAST21
Transmembranei34 – 54Helical; Name=2Sequence analysisAdd BLAST21
Transmembranei62 – 82Helical; Name=3Sequence analysisAdd BLAST21
Transmembranei110 – 130Helical; Name=4Sequence analysisAdd BLAST21
Transmembranei139 – 159Helical; Name=5Sequence analysisAdd BLAST21
Transmembranei166 – 186Helical; Name=6Sequence analysisAdd BLAST21
Transmembranei218 – 238Helical; Name=7Sequence analysisAdd BLAST21
Transmembranei268 – 288Helical; Name=8Sequence analysisAdd BLAST21
Transmembranei331 – 351Helical; Name=9Sequence analysisAdd BLAST21

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywords - Cellular componenti

Lysosome, Membrane

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

Organism-specific databases

DisGeNET

More...
DisGeNETi
53346

Open Targets

More...
OpenTargetsi
ENSG00000136404

The Pharmacogenetics and Pharmacogenomics Knowledge Base

More...
PharmGKBi
PA36561

Miscellaneous databases

Pharos NIH Druggable Genome Knowledgebase

More...
Pharosi
Q9BZW5 Tdark

Polymorphism and mutation databases

BioMuta curated single-nucleotide variation and disease association database

More...
BioMutai
TM6SF1

Domain mapping of disease mutations (DMDM)

More...
DMDMi
209572686

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘PTM / Processing’ section describes the extent of a polypeptide chain in the mature protein following processing.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00001818331 – 370Transmembrane 6 superfamily member 1Add BLAST370

Proteomic databases

jPOST - Japan Proteome Standard Repository/Database

More...
jPOSTi
Q9BZW5

MassIVE - Mass Spectrometry Interactive Virtual Environment

More...
MassIVEi
Q9BZW5

MaxQB - The MaxQuant DataBase

More...
MaxQBi
Q9BZW5

PaxDb, a database of protein abundance averages across all three domains of life

More...
PaxDbi
Q9BZW5

PeptideAtlas

More...
PeptideAtlasi
Q9BZW5

PRoteomics IDEntifications database

More...
PRIDEi
Q9BZW5

ProteomicsDB: a multi-organism proteome resource

More...
ProteomicsDBi
42833
79911 [Q9BZW5-1]

PTM databases

iPTMnet integrated resource for PTMs in systems biology context

More...
iPTMneti
Q9BZW5

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

<p>This subsection of the ‘Expression’ section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms. By default, the information is derived from experiments at the mRNA level, unless specified ‘at protein level’. <br></br>Examples: <a href="http://www.uniprot.org/uniprot/P92958#expression">P92958</a>, <a href="http://www.uniprot.org/uniprot/Q8TDN4#expression">Q8TDN4</a>, <a href="http://www.uniprot.org/uniprot/O14734#expression">O14734</a><p><a href='/help/tissue_specificity' target='_top'>More...</a></p>Tissue specificityi

Enhanced expression in spleen, testis and peripheral blood leukocytes.

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...
Bgeei
ENSG00000136404 Expressed in 175 organ(s), highest expression level in muscle of leg

ExpressionAtlas, Differential and Baseline Expression

More...
ExpressionAtlasi
Q9BZW5 baseline and differential

Genevisible search portal to normalized and curated expression data from Genevestigator

More...
Genevisiblei
Q9BZW5 HS

Organism-specific databases

Human Protein Atlas

More...
HPAi
HPA016051
HPA056857

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

Protein-protein interaction databases

The Biological General Repository for Interaction Datasets (BioGrid)

More...
BioGridi
119747, 1 interactor

STRING: functional protein association networks

More...
STRINGi
9606.ENSP00000317000

Miscellaneous databases

RNAct, Protein-RNA interaction predictions for model organisms.

More...
RNActi
Q9BZW5 protein

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

SWISS-MODEL Repository - a database of annotated 3D protein structure models

More...
SMRi
Q9BZW5

Database of comparative protein structure models

More...
ModBasei
Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family_and_domains_section">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini60 – 185EXPERA 1PROSITE-ProRule annotationAdd BLAST126
Domaini216 – 350EXPERA 2PROSITE-ProRule annotationAdd BLAST135

<p>This subsection of the ‘Family and domains’ section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Belongs to the TM6SF family.Curated

Keywords - Domaini

Repeat, Transmembrane, Transmembrane helix

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
ENOG410IJ78 Eukaryota
ENOG41113JR LUCA

Ensembl GeneTree

More...
GeneTreei
ENSGT00390000012913

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...
HOGENOMi
HOG000035128

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
Q9BZW5

Identification of Orthologs from Complete Genome Data

More...
OMAi
RCVNKPE

Database of Orthologous Groups

More...
OrthoDBi
784438at2759

Database for complete collections of gene phylogenies

More...
PhylomeDBi
Q9BZW5

TreeFam database of animal gene trees

More...
TreeFami
TF333088

Family and domain databases

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR033118 EXPERA

PROSITE; a protein domain and family database

More...
PROSITEi
View protein in PROSITE
PS51751 EXPERA, 2 hits

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequences (2+)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

This entry describes 2 <p>This subsection of the ‘Sequence’ section lists the alternative protein sequences (isoforms) that can be generated from the same gene by a single or by the combination of up to four biological events (alternative promoter usage, alternative splicing, alternative initiation and ribosomal frameshifting). Additionally, this section gives relevant information on each alternative protein isoform.<p><a href='/help/alternative_products' target='_top'>More...</a></p> isoformsi produced by alternative splicing. AlignAdd to basket

This entry has 2 described isoforms and 5 potential isoforms that are computationally mapped.Show allAlign All

Isoform 1 (identifier: Q9BZW5-1) [UniParc]FASTAAdd to basket

This isoform has been chosen as the <div> <p><b>What is the canonical sequence?</b><p><a href='/help/canonical_and_isoforms' target='_top'>More...</a></p>canonicali sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

« Hide
        10         20         30         40         50
MSASAATGVF VLSLSAIPVT YVFNHLAAQH DSWTIVGVAA LILFLVALLA
60 70 80 90 100
RVLVKRKPPR DPLFYVYAVF GFTSVVNLII GLEQDGIIDG FMTHYLREGE
110 120 130 140 150
PYLNTAYGHM ICYWDGSAHY LMYLVMVAAI AWEETYRTIG LYWVGSIIMS
160 170 180 190 200
VVVFVPGNIV GKYGTRICPA FFLSIPYTCL PVWAGFRIYN QPSENYNYPS
210 220 230 240 250
KVIQEAQAKD LLRRPFDLML VVCLLLATGF CLFRGLIALD CPSELCRLYT
260 270 280 290 300
QFQEPYLKDP AAYPKIQMLA YMFYSVPYFV TALYGLVVPG CSWMPDITLI
310 320 330 340 350
HAGGLAQAQF SHIGASLHAR TAYVYRVPEE AKILFLALNI AYGVLPQLLA
360 370
YRCIYKPEFF IKTKAEEKVE
Length:370
Mass (Da):41,636
Last modified:October 14, 2008 - v2
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i57E0BC11BBF16D68
GO
Isoform 2 (identifier: Q9BZW5-2) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     237-267: Missing.

Show »
Length:339
Mass (Da):38,039
Checksum:i68DE5CBDE5E2B743
GO

<p>In eukaryotic reference proteomes, unreviewed entries that are likely to belong to the same gene are computationally mapped, based on gene identifiers from Ensembl, EnsemblGenomes and model organism databases.<p><a href='/help/gene_centric_isoform_mapping' target='_top'>More...</a></p>Computationally mapped potential isoform sequencesi

There are 5 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
Q8N5N8Q8N5N8_HUMAN
TM6SF1 protein
TM6SF1
145Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
Q6P4D7Q6P4D7_HUMAN
TM6SF1 protein
TM6SF1
188Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
E9PD04E9PD04_HUMAN
Transmembrane 6 superfamily member ...
TM6SF1
133Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
H3BM84H3BM84_HUMAN
Transmembrane 6 superfamily member ...
TM6SF1
166Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
H3BMK0H3BMK0_HUMAN
Transmembrane 6 superfamily member ...
TM6SF1
30Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Sequence’ section reports difference(s) between the canonical sequence (displayed by default in the entry) and the different sequence submissions merged in the entry. These various submissions may originate from different sequencing projects, different types of experiments, or different biological samples. Sequence conflicts are usually of unknown origin.<p><a href='/help/conflict' target='_top'>More...</a></p>Sequence conflicti11V → M in AAY44754 (Ref. 2) Curated1
Sequence conflicti201K → R in AAY44754 (Ref. 2) Curated1
Sequence conflicti341A → V in AAG59699 (PubMed:11124529).Curated1

Natural variant

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Sequence’ section describes natural variant(s) of the protein sequence.<p><a href='/help/variant' target='_top'>More...</a></p>Natural variantiVAR_01284417I → T. Corresponds to variant dbSNP:rs1062232Ensembl.1
Natural variantiVAR_02466159P → S. Corresponds to variant dbSNP:rs1989Ensembl.1

Alternative sequence

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Sequence’ section describes the sequence of naturally occurring alternative protein isoform(s). The changes in the amino acid sequence may be due to alternative splicing, alternative promoter usage, alternative initiation, or ribosomal frameshifting.<p><a href='/help/var_seq' target='_top'>More...</a></p>Alternative sequenceiVSP_045697237 – 267Missing in isoform 2. 1 PublicationAdd BLAST31

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

More...
GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
AF255922 mRNA Translation: AAG59699.1
DQ021909 mRNA Translation: AAY44754.1
AK292100 mRNA Translation: BAF84789.1
AC024270 Genomic DNA No translation available.
CH471188 Genomic DNA Translation: EAW62428.1

The Consensus CDS (CCDS) project

More...
CCDSi
CCDS10323.1 [Q9BZW5-1]
CCDS45338.1 [Q9BZW5-2]

NCBI Reference Sequences

More...
RefSeqi
NP_001138375.1, NM_001144903.1 [Q9BZW5-2]
NP_075379.2, NM_023003.3 [Q9BZW5-1]

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...
Ensembli
ENST00000322019; ENSP00000317000; ENSG00000136404 [Q9BZW5-1]
ENST00000565774; ENSP00000457477; ENSG00000136404 [Q9BZW5-2]

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
53346

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
hsa:53346

UCSC genome browser

More...
UCSCi
uc002bjp.4 human [Q9BZW5-1]

Keywords - Coding sequence diversityi

Alternative splicing, Polymorphism

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF255922 mRNA Translation: AAG59699.1
DQ021909 mRNA Translation: AAY44754.1
AK292100 mRNA Translation: BAF84789.1
AC024270 Genomic DNA No translation available.
CH471188 Genomic DNA Translation: EAW62428.1
CCDSiCCDS10323.1 [Q9BZW5-1]
CCDS45338.1 [Q9BZW5-2]
RefSeqiNP_001138375.1, NM_001144903.1 [Q9BZW5-2]
NP_075379.2, NM_023003.3 [Q9BZW5-1]

3D structure databases

SMRiQ9BZW5
ModBaseiSearch...

Protein-protein interaction databases

BioGridi119747, 1 interactor
STRINGi9606.ENSP00000317000

Protein family/group databases

TCDBi8.A.93.2.4 the sigma2 receptor or tmem97 (s2r) family

PTM databases

iPTMnetiQ9BZW5

Polymorphism and mutation databases

BioMutaiTM6SF1
DMDMi209572686

Proteomic databases

jPOSTiQ9BZW5
MassIVEiQ9BZW5
MaxQBiQ9BZW5
PaxDbiQ9BZW5
PeptideAtlasiQ9BZW5
PRIDEiQ9BZW5
ProteomicsDBi42833
79911 [Q9BZW5-1]

Protocols and materials databases

The DNASU plasmid repository

More...
DNASUi
53346

Genome annotation databases

EnsembliENST00000322019; ENSP00000317000; ENSG00000136404 [Q9BZW5-1]
ENST00000565774; ENSP00000457477; ENSG00000136404 [Q9BZW5-2]
GeneIDi53346
KEGGihsa:53346
UCSCiuc002bjp.4 human [Q9BZW5-1]

Organism-specific databases

Comparative Toxicogenomics Database

More...
CTDi
53346
DisGeNETi53346
EuPathDBiHostDB:ENSG00000136404.15

GeneCards: human genes, protein and diseases

More...
GeneCardsi
TM6SF1
HGNCiHGNC:11860 TM6SF1
HPAiHPA016051
HPA056857
MIMi606562 gene
neXtProtiNX_Q9BZW5
OpenTargetsiENSG00000136404
PharmGKBiPA36561

GenAtlas: human gene database

More...
GenAtlasi
Search...

Phylogenomic databases

eggNOGiENOG410IJ78 Eukaryota
ENOG41113JR LUCA
GeneTreeiENSGT00390000012913
HOGENOMiHOG000035128
InParanoidiQ9BZW5
OMAiRCVNKPE
OrthoDBi784438at2759
PhylomeDBiQ9BZW5
TreeFamiTF333088

Miscellaneous databases

ChiTaRS: a database of human, mouse and fruit fly chimeric transcripts and RNA-sequencing data

More...
ChiTaRSi
TM6SF1 human

Database of phenotypes from RNA interference screens in Drosophila and Homo sapiens

More...
GenomeRNAii
53346
PharosiQ9BZW5 Tdark

Protein Ontology

More...
PROi
PR:Q9BZW5
RNActiQ9BZW5 protein

The Stanford Online Universal Resource for Clones and ESTs

More...
SOURCEi
Search...

Gene expression databases

BgeeiENSG00000136404 Expressed in 175 organ(s), highest expression level in muscle of leg
ExpressionAtlasiQ9BZW5 baseline and differential
GenevisibleiQ9BZW5 HS

Family and domain databases

InterProiView protein in InterPro
IPR033118 EXPERA
PROSITEiView protein in PROSITE
PS51751 EXPERA, 2 hits

ProtoNet; Automatic hierarchical classification of proteins

More...
ProtoNeti
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the ‘Entry information’ section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiTM6S1_HUMAN
<p>This subsection of the ‘Entry information’ section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called ‘Primary (citable) accession number’.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q9BZW5
Secondary accession number(s): A8K7T5, H3BU56, Q4U0U5
<p>This subsection of the ‘Entry information’ section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification (‘Last modified’). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: March 27, 2002
Last sequence update: October 14, 2008
Last modified: December 11, 2019
This is version 121 of the entry and version 2 of the sequence. See complete history.
<p>This subsection of the ‘Entry information’ section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families
  2. Human entries with polymorphisms or disease mutations
    List of human entries with polymorphisms or disease mutations
  3. Human polymorphisms and disease mutations
    Index of human polymorphisms and disease mutations
  4. MIM cross-references
    Online Mendelian Inheritance in Man (MIM) cross-references in UniProtKB/Swiss-Prot
  5. Human chromosome 15
    Human chromosome 15: entries, gene names and cross-references to MIM
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