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UniProtKB - Q9BZF2 (OSBL7_HUMAN)

Entry version 140 (08 May 2019)
Sequence version 1 (01 Jun 2001)
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Protein

Oxysterol-binding protein-related protein 7

Gene

OSBPL7

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score:

Annotation score:5 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the ‘protein existence’ evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

View the complete GO annotation on QuickGO ...

GO - Biological processi

View the complete GO annotation on QuickGO ...

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Biological processLipid transport, Transport
LigandLipid-binding

Enzyme and pathway databases

Reactome - a knowledgebase of biological pathways and processes

More...Reactomei		R-HSA-192105 Synthesis of bile acids and bile salts

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Oxysterol-binding protein-related protein 7
Short name:
ORP-7
Short name:
OSBP-related protein 7
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: ‘Name’, ‘Synonyms’, ‘Ordered locus names’ and ‘ORF names’.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:OSBPL7
Synonyms:ORP7
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiHomo sapiens (Human)
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the ‘taxonomic identifier’ or ‘taxid’.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri9606 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Primates › Haplorrhini › Catarrhini › Hominidae › Homo
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000005640 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes_manual">proteome</a> can consist of several components. <br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 17

Organism-specific databases

Human Gene Nomenclature Database

More...HGNCi		HGNC:16387 OSBPL7

Online Mendelian Inheritance in Man (OMIM)

More...MIMi		606735 gene

neXtProt; the human protein knowledge platform

More...neXtProti		NX_Q9BZF2

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte & Seán O’Donoghue; Source: COMPARTMENTS

Keywords - Cellular componenti

Cell membrane, Cytoplasm, Endoplasmic reticulum, Membrane

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

Organism-specific databases

Open Targets

More...OpenTargetsi		ENSG00000006025

The Pharmacogenetics and Pharmacogenomics Knowledge Base

More...PharmGKBi		PA32831

Polymorphism and mutation databases

BioMuta curated single-nucleotide variation and disease association database

More...BioMutai		OSBPL7

Domain mapping of disease mutations (DMDM)

More...DMDMi		20139132

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘PTM / Processing’ section describes the extent of a polypeptide chain in the mature protein following processing.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00001003771 – 842Oxysterol-binding protein-related protein 7Add BLAST842

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘PTM / Processing’ section specifies the position and type of each modified residue excluding <a href="http://www.uniprot.org/manual/lipid">lipids</a>, <a href="http://www.uniprot.org/manual/carbohyd">glycans</a> and <a href="http://www.uniprot.org/manual/crosslnk">protein cross-links</a>.<p><a href='/help/mod_res' target='_top'>More...</a></p>Modified residuei171PhosphothreonineCombined sources1
Modified residuei217PhosphoserineCombined sources1
Modified residuei226PhosphoserineCombined sources1
Modified residuei256PhosphoserineCombined sources1
Modified residuei272PhosphoserineCombined sources1

Keywords - PTMi

Phosphoprotein

Proteomic databases

Encyclopedia of Proteome Dynamics

More...EPDi		Q9BZF2

jPOST - Japan Proteome Standard Repository/Database

More...jPOSTi		Q9BZF2

MaxQB - The MaxQuant DataBase

More...MaxQBi		Q9BZF2

PaxDb, a database of protein abundance averages across all three domains of life

More...PaxDbi		Q9BZF2

PeptideAtlas

More...PeptideAtlasi		Q9BZF2

PRoteomics IDEntifications database

More...PRIDEi		Q9BZF2

ProteomicsDB human proteome resource

More...ProteomicsDBi		79830

PTM databases

iPTMnet integrated resource for PTMs in systems biology context

More...iPTMneti		Q9BZF2

Comprehensive resource for the study of protein post-translational modifications (PTMs) in human, mouse and rat.

More...PhosphoSitePlusi		Q9BZF2

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

<p>This subsection of the ‘Expression’ section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms. By default, the information is derived from experiments at the mRNA level, unless specified ‘at protein level’. <br></br>Examples: <a href="http://www.uniprot.org/uniprot/P92958#expression">P92958</a>, <a href="http://www.uniprot.org/uniprot/Q8TDN4#expression">Q8TDN4</a>, <a href="http://www.uniprot.org/uniprot/O14734#expression">O14734</a><p><a href='/help/tissue_specificity' target='_top'>More...</a></p>Tissue specificityi

Expressed in epithelium of small and large intestines (at protein level). Expressed in stomach, duodenum, jejunum, ascending colon, spleen, thymus, lymph node, trachea and leukocytes.1 Publication

<p>This subsection of the ‘Expression’ section provides information on the expression of the gene product at various stages of a cell, tissue or organism development. By default, the information is derived from experiments at the mRNA level, unless specified ‘at the protein level’.<p><a href='/help/developmental_stage' target='_top'>More...</a></p>Developmental stagei

Expressed in fetal lung and thymus.1 Publication

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...Bgeei		ENSG00000006025 Expressed in 160 organ(s), highest expression level in fundus of stomach

ExpressionAtlas, Differential and Baseline Expression

More...ExpressionAtlasi		Q9BZF2 baseline and differential

Genevisible search portal to normalized and curated expression data from Genevestigator

More...Genevisiblei		Q9BZF2 HS

Organism-specific databases

Human Protein Atlas

More...HPAi		HPA036076
HPA053083

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

Protein-protein interaction databases

The Biological General Repository for Interaction Datasets (BioGrid)

More...BioGridi		125382, 2 interactors

The Eukaryotic Linear Motif resource for Functional Sites in Proteins

More...ELMi		Q9BZF2

Protein interaction database and analysis system

More...IntActi		Q9BZF2, 1 interactor

STRING: functional protein association networks

More...STRINGi		9606.ENSP00000007414

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

SWISS-MODEL Repository - a database of annotated 3D protein structure models

More...SMRi		Q9BZF2

Database of comparative protein structure models

More...ModBasei		Search...

MobiDB: a database of protein disorder and mobility annotations

More...MobiDBi		Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family_and_domains_section">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini47 – 142PHPROSITE-ProRule annotationAdd BLAST96

<p>This subsection of the ‘Family and domains’ section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Belongs to the OSBP family.Curated

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...eggNOGi		KOG1737 Eukaryota
ENOG410XP9E LUCA

Ensembl GeneTree

More...GeneTreei		ENSGT00940000157439

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...HOGENOMi		HOG000231072

InParanoid: Eukaryotic Ortholog Groups

More...InParanoidi		Q9BZF2

KEGG Orthology (KO)

More...KOi		K20463

Identification of Orthologs from Complete Genome Data

More...OMAi		EGIMPER

Database of Orthologous Groups

More...OrthoDBi		542090at2759

Database for complete collections of gene phylogenies

More...PhylomeDBi		Q9BZF2

TreeFam database of animal gene trees

More...TreeFami		TF320922

Family and domain databases

Gene3D Structural and Functional Annotation of Protein Families

More...Gene3Di		2.30.29.30, 1 hit

Integrated resource of protein families, domains and functional sites

More...InterProi		View protein in InterPro
IPR037239 OSBP_sf
IPR000648 Oxysterol-bd
IPR018494 Oxysterol-bd_CS
IPR011993 PH-like_dom_sf
IPR041680 PH_8
IPR001849 PH_domain

The PANTHER Classification System

More...PANTHERi		PTHR10972 PTHR10972, 1 hit

Pfam protein domain database

More...Pfami		View protein in Pfam
PF01237 Oxysterol_BP, 1 hit
PF15409 PH_8, 1 hit

Simple Modular Architecture Research Tool; a protein domain database

More...SMARTi		View protein in SMART
SM00233 PH, 1 hit

Superfamily database of structural and functional annotation

More...SUPFAMi		SSF144000 SSF144000, 1 hit

PROSITE; a protein domain and family database

More...PROSITEi		View protein in PROSITE
PS01013 OSBP, 1 hit
PS50003 PH_DOMAIN, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>.<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequences (2+)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

This entry describes 2 <p>This subsection of the ‘Sequence’ section lists the alternative protein sequences (isoforms) that can be generated from the same gene by a single or by the combination of up to four biological events (alternative promoter usage, alternative splicing, alternative initiation and ribosomal frameshifting). Additionally, this section gives relevant information on each alternative protein isoform.<p><a href='/help/alternative_products' target='_top'>More...</a></p> isoformsi produced by alternative splicing. AlignAdd to basket

This entry has 2 described isoforms and 2 potential isoforms that are computationally mapped.Show allAlign All

Isoform 1 (identifier: Q9BZF2-1) [UniParc]FASTAAdd to basket

This isoform has been chosen as the 'canonical' sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

« Hide
        10         20         30         40         50
MDFQERDPPF LPESAQSSKP SSAQQASELW EVVEEPRVRL GTEGVMPERQ 
        60         70         80         90        100
EGHLLKKRKW PLKGWHKRYF VLEDGILHYA TTRQDITKGK LHGSIDVRLS 
       110        120        130        140        150
VMSINKKAQR IDLDTEDNIY HLKIKSQDLF QSWVAQLRAH RLAHRLDMPR 
       160        170        180        190        200
GSLPSTAHRK VPGAQLPTAA TASALPGLGP REKVSSWLRD SDGLDRCSHE 
       210        220        230        240        250
LSECQGKLQE LHRLLQSLES LHRIPSAPVI PTHQASVTTE RPKKGKRTSR 
       260        270        280        290        300
MWCTQSFAKD DTIGRVGRLH GSVPNLSRYL ESRDSSGTRG LPPTDYAHLQ 
       310        320        330        340        350
RSFWALAQKV HSSLSSVLAA LTMERDQLRD MHQGSELSRM GVSEASTGQR 
       360        370        380        390        400
RLHSLSTSSD TTADSFSSLN PEEQEALYMK GRELTPQLSQ TSILSLADSH 
       410        420        430        440        450
TEFFDACEVL LSASSSENEG SEEEESCTSE ITTSLSEEML DLRGAERCQK 
       460        470        480        490        500
GGCVPGRPMG PPRRRCLPAA SGPGADVSLW NILRNNIGKD LSKVSMPVQL 
       510        520        530        540        550
NEPLNTLQRL CEELEYSSLL DQASRIADPC ERMVYIAAFA VSAYSSTYHR 
       560        570        580        590        600
AGCKPFNPVL GETYECERPD RGFRFISEQV SHHPPISACH AESENFAFWQ 
       610        620        630        640        650
DMKWKNKFWG KSLEIVPVGT VNVSLPRFGD HFEWNKVTSC IHNVLSGQRW 
       660        670        680        690        700
IEHYGEVLIR NTQDSSCHCK ITFCKAKYWS SNVHEVQGAV LSRSGRVLHR 
       710        720        730        740        750
LFGKWHEGLY RGPTPGGQCI WKPNSMPPDH ERNFGFTQFA LELNELTAEL 
       760        770        780        790        800
KRSLPSTDTR LRPDQRYLEE GNIQAAEAQK RRIEQLQRDR RKVMEENNIV 
       810        820        830        840 
HQARFFRRQT DSSGKEWWVT NNTYWRLRAE PGYGNMDGAV LW
Length:842
Mass (Da):95,432
Last modified:June 1, 2001 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i6DE6ED596CEE6FE3
GO
Isoform 2 (identifier: Q9BZF2-2) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     343-357: SEASTGQRRLHSLST → RPGGQGDWCGERASS
     358-842: Missing.

Show »
Length:357
Mass (Da):40,186
Checksum:iE14AB73FCCB16D1C
GO

<p>In eukaryotic reference proteomes, unreviewed entries that are likely to belong to the same gene are computationally mapped, based on gene identifiers from Ensembl, EnsemblGenomes and model organism databases.<p><a href='/help/gene_centric_isoform_mapping' target='_top'>More...</a></p>Computationally mapped potential isoform sequencesi

There are 2 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
J3QLK7J3QLK7_HUMAN
Oxysterol-binding protein-related p...
OSBPL7
420Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
J3QSC2J3QSC2_HUMAN
Oxysterol-binding protein-related p...
OSBPL7
19Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>

Natural variant

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Sequence’ section describes natural variant(s) of the protein sequence.<p><a href='/help/variant' target='_top'>More...</a></p>Natural variantiVAR_060080148M → I. Corresponds to variant dbSNP:rs8076196Ensembl.1
Natural variantiVAR_053551156T → I. Corresponds to variant dbSNP:rs35437144Ensembl.1
Natural variantiVAR_060081169A → E. Corresponds to variant dbSNP:rs8071195Ensembl.1

Alternative sequence

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Sequence’ section describes the sequence of naturally occurring alternative protein isoform(s). The changes in the amino acid sequence may be due to alternative splicing, alternative promoter usage, alternative initiation, or ribosomal frameshifting.<p><a href='/help/var_seq' target='_top'>More...</a></p>Alternative sequenceiVSP_057227343 – 357SEAST…HSLST → RPGGQGDWCGERASS in isoform 2. 2 PublicationsAdd BLAST15
Alternative sequenceiVSP_057228358 – 842Missing in isoform 2. 2 PublicationsAdd BLAST485

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...EMBLi

GenBank nucleotide sequence database

More...GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...DDBJi
Links Updated
AF323729 mRNA Translation: AAG53410.1
AK289523 mRNA Translation: BAF82212.1
AC003665 Genomic DNA No translation available.
CH471109 Genomic DNA Translation: EAW94800.1
CH471109 Genomic DNA Translation: EAW94801.1
CH471109 Genomic DNA Translation: EAW94802.1
CH471109 Genomic DNA Translation: EAW94803.1
BC028010 mRNA Translation: AAH28010.1
BC065482 mRNA Translation: AAH65482.1

The Consensus CDS (CCDS) project

More...CCDSi		CCDS11515.1 [Q9BZF2-1]

NCBI Reference Sequences

More...RefSeqi		NP_665741.1, NM_145798.2 [Q9BZF2-1]

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...Ensembli		ENST00000007414; ENSP00000007414; ENSG00000006025 [Q9BZF2-1]
ENST00000392507; ENSP00000376295; ENSG00000006025 [Q9BZF2-1]
ENST00000613735; ENSP00000479827; ENSG00000006025 [Q9BZF2-2]

Database of genes from NCBI RefSeq genomes

More...GeneIDi		114881

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...KEGGi		hsa:114881

UCSC genome browser

More...UCSCi		uc002ilx.2 human [Q9BZF2-1]

Keywords - Coding sequence diversityi

Alternative splicing, Polymorphism

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF323729 mRNA Translation: AAG53410.1
AK289523 mRNA Translation: BAF82212.1
AC003665 Genomic DNA No translation available.
CH471109 Genomic DNA Translation: EAW94800.1
CH471109 Genomic DNA Translation: EAW94801.1
CH471109 Genomic DNA Translation: EAW94802.1
CH471109 Genomic DNA Translation: EAW94803.1
BC028010 mRNA Translation: AAH28010.1
BC065482 mRNA Translation: AAH65482.1
CCDSiCCDS11515.1 [Q9BZF2-1]
RefSeqiNP_665741.1, NM_145798.2 [Q9BZF2-1]

3D structure databases

SMRiQ9BZF2
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi125382, 2 interactors
ELMiQ9BZF2
IntActiQ9BZF2, 1 interactor
STRINGi9606.ENSP00000007414

PTM databases

iPTMnetiQ9BZF2
PhosphoSitePlusiQ9BZF2

Polymorphism and mutation databases

BioMutaiOSBPL7
DMDMi20139132

Proteomic databases

EPDiQ9BZF2
jPOSTiQ9BZF2
MaxQBiQ9BZF2
PaxDbiQ9BZF2
PeptideAtlasiQ9BZF2
PRIDEiQ9BZF2
ProteomicsDBi79830

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENST00000007414; ENSP00000007414; ENSG00000006025 [Q9BZF2-1]
ENST00000392507; ENSP00000376295; ENSG00000006025 [Q9BZF2-1]
ENST00000613735; ENSP00000479827; ENSG00000006025 [Q9BZF2-2]
GeneIDi114881
KEGGihsa:114881
UCSCiuc002ilx.2 human [Q9BZF2-1]

Organism-specific databases

Comparative Toxicogenomics Database

More...CTDi		114881

GeneCards: human genes, protein and diseases

More...GeneCardsi		OSBPL7
HGNCiHGNC:16387 OSBPL7
HPAiHPA036076
HPA053083
MIMi606735 gene
neXtProtiNX_Q9BZF2
OpenTargetsiENSG00000006025
PharmGKBiPA32831

GenAtlas: human gene database

More...GenAtlasi		Search...

Phylogenomic databases

eggNOGiKOG1737 Eukaryota
ENOG410XP9E LUCA
GeneTreeiENSGT00940000157439
HOGENOMiHOG000231072
InParanoidiQ9BZF2
KOiK20463
OMAiEGIMPER
OrthoDBi542090at2759
PhylomeDBiQ9BZF2
TreeFamiTF320922

Enzyme and pathway databases

ReactomeiR-HSA-192105 Synthesis of bile acids and bile salts

Miscellaneous databases

ChiTaRS: a database of human, mouse and fruit fly chimeric transcripts and RNA-sequencing data

More...ChiTaRSi		OSBPL7 human

Database of phenotypes from RNA interference screens in Drosophila and Homo sapiens

More...GenomeRNAii		114881

Protein Ontology

More...PROi		PR:Q9BZF2

The Stanford Online Universal Resource for Clones and ESTs

More...SOURCEi		Search...

Gene expression databases

BgeeiENSG00000006025 Expressed in 160 organ(s), highest expression level in fundus of stomach
ExpressionAtlasiQ9BZF2 baseline and differential
GenevisibleiQ9BZF2 HS

Family and domain databases

Gene3Di2.30.29.30, 1 hit
InterProiView protein in InterPro
IPR037239 OSBP_sf
IPR000648 Oxysterol-bd
IPR018494 Oxysterol-bd_CS
IPR011993 PH-like_dom_sf
IPR041680 PH_8
IPR001849 PH_domain
PANTHERiPTHR10972 PTHR10972, 1 hit
PfamiView protein in Pfam
PF01237 Oxysterol_BP, 1 hit
PF15409 PH_8, 1 hit
SMARTiView protein in SMART
SM00233 PH, 1 hit
SUPFAMiSSF144000 SSF144000, 1 hit
PROSITEiView protein in PROSITE
PS01013 OSBP, 1 hit
PS50003 PH_DOMAIN, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

More...ProtoNeti		Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the ‘Entry information’ section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiOSBL7_HUMAN
<p>This subsection of the ‘Entry information’ section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called ‘Primary (citable) accession number’.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q9BZF2
Secondary accession number(s): D3DTT6, Q6PIV6
<p>This subsection of the ‘Entry information’ section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification (‘Last modified’). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: February 11, 2002
Last sequence update: June 1, 2001
Last modified: May 8, 2019
This is version 140 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the ‘Entry information’ section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Human chromosome 17
    Human chromosome 17: entries, gene names and cross-references to MIM
  2. SIMILARITY comments
    Index of protein domains and families
  3. Human entries with polymorphisms or disease mutations
    List of human entries with polymorphisms or disease mutations
  4. Human polymorphisms and disease mutations
    Index of human polymorphisms and disease mutations
  5. MIM cross-references
    Online Mendelian Inheritance in Man (MIM) cross-references in UniProtKB/Swiss-Prot
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