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Protein

Sulfiredoxin-1

Gene

SRXN1

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score:

Annotation score:5 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the ‘protein existence’ evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Contributes to oxidative stress resistance by reducing cysteine-sulfinic acid formed under exposure to oxidants in the peroxiredoxins PRDX1, PRDX2, PRDX3 and PRDX4. Does not act on PRDX5 or PRDX6. May catalyze the reduction in a multi-step process by acting both as a specific phosphotransferase and a thioltransferase.2 Publications

<p>This subsection of the <a href="http://www.uniprot.org/help/function_section">Function</a> section describes the catalytic activity of an enzyme, i.e. a chemical reaction that the enzyme catalyzes.<p><a href='/help/catalytic_activity' target='_top'>More...</a></p>Catalytic activityi

<p>This subsection of the ‘Function’ section provides information relevant to cofactors. A cofactor is any non-protein substance required for a protein to be catalytically active. Some cofactors are inorganic, such as the metal atoms zinc, iron, and copper in various oxidation states. Others, such as most vitamins, are organic.<p><a href='/help/cofactor' target='_top'>More...</a></p>Cofactori

Mg2+By similarity

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Function’ section describes a region in the protein which binds nucleotide phosphates. It always involves more than one amino acid and includes all residues involved in nucleotide-binding.<p><a href='/help/np_bind' target='_top'>More...</a></p>Nucleotide bindingi98 – 101ATP4

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

  • ATP binding Source: UniProtKB-KW
  • oxidoreductase activity, acting on a sulfur group of donors Source: UniProtKB
  • sulfiredoxin activity Source: GO_Central

GO - Biological processi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Molecular functionAntioxidant, Oxidoreductase
LigandATP-binding, Magnesium, Nucleotide-binding

Enzyme and pathway databases

BRENDA Comprehensive Enzyme Information System

More...
BRENDAi
1.8.98.2 2681

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Sulfiredoxin-1 (EC:1.8.98.2)
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: ‘Name’, ‘Synonyms’, ‘Ordered locus names’ and ‘ORF names’.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:SRXN1
Synonyms:C20orf139, SRX, SRX1
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiHomo sapiens (Human)
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the ‘taxonomic identifier’ or ‘taxid’.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri9606 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000005640 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes_manual">proteome</a> can consist of several components. <br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 20

Organism-specific databases

Eukaryotic Pathogen Database Resources

More...
EuPathDBi
HostDB:ENSG00000271303.1

Human Gene Nomenclature Database

More...
HGNCi
HGNC:16132 SRXN1

Online Mendelian Inheritance in Man (OMIM)

More...
MIMi
617583 gene

neXtProt; the human protein knowledge platform

More...
neXtProti
NX_Q9BYN0

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

Cytoplasm

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

Mutagenesis

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/manual/pathology_and_biotech_section">'Pathology and Biotech'</a> section describes the effect of the experimental mutation of one or more amino acid(s) on the biological properties of the protein.<p><a href='/help/mutagen' target='_top'>More...</a></p>Mutagenesisi99C → S: No effect on association with PRDX1, PRDX2, PRDX3 or PRDX4. 1 Publication1

Organism-specific databases

DisGeNET

More...
DisGeNETi
140809

Open Targets

More...
OpenTargetsi
ENSG00000271303

The Pharmacogenetics and Pharmacogenomics Knowledge Base

More...
PharmGKBi
PA25681

Polymorphism and mutation databases

BioMuta curated single-nucleotide variation and disease association database

More...
BioMutai
SRXN1

Domain mapping of disease mutations (DMDM)

More...
DMDMi
30315944

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘PTM / Processing’ section describes the extent of a polypeptide chain in the mature protein following processing.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00002114311 – 137Sulfiredoxin-1Add BLAST137

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘PTM / Processing’ section specifies the position and type of each modified residue excluding <a href="http://www.uniprot.org/manual/lipid">lipids</a>, <a href="http://www.uniprot.org/manual/carbohyd">glycans</a> and <a href="http://www.uniprot.org/manual/crosslnk">protein cross-links</a>.<p><a href='/help/mod_res' target='_top'>More...</a></p>Modified residuei11Omega-N-methylarginineCombined sources1
Modified residuei16Omega-N-methylarginineCombined sources1
Modified residuei32PhosphoserineCombined sources1
<p>This subsection of the PTM / Processing":/help/ptm_processing_section section describes the positions of cysteine residues participating in disulfide bonds.<p><a href='/help/disulfid' target='_top'>More...</a></p>Disulfide bondi99InterchainBy similarity

Keywords - PTMi

Disulfide bond, Methylation, Phosphoprotein

Proteomic databases

Encyclopedia of Proteome Dynamics

More...
EPDi
Q9BYN0

jPOST - Japan Proteome Standard Repository/Database

More...
jPOSTi
Q9BYN0

MaxQB - The MaxQuant DataBase

More...
MaxQBi
Q9BYN0

PaxDb, a database of protein abundance averages across all three domains of life

More...
PaxDbi
Q9BYN0

PeptideAtlas

More...
PeptideAtlasi
Q9BYN0

PRoteomics IDEntifications database

More...
PRIDEi
Q9BYN0

ProteomicsDB human proteome resource

More...
ProteomicsDBi
79670

PTM databases

iPTMnet integrated resource for PTMs in systems biology context

More...
iPTMneti
Q9BYN0

Comprehensive resource for the study of protein post-translational modifications (PTMs) in human, mouse and rat.

More...
PhosphoSitePlusi
Q9BYN0

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

<p>This subsection of the ‘Expression’ section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms. By default, the information is derived from experiments at the mRNA level, unless specified ‘at protein level’. <br></br>Examples: <a href="http://www.uniprot.org/uniprot/P92958#expression">P92958</a>, <a href="http://www.uniprot.org/uniprot/Q8TDN4#expression">Q8TDN4</a>, <a href="http://www.uniprot.org/uniprot/O14734#expression">O14734</a><p><a href='/help/tissue_specificity' target='_top'>More...</a></p>Tissue specificityi

Widely expressed with highest levels in kidney, lung, spleen and thymus.1 Publication

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...
Bgeei
ENSG00000271303 Expressed in 94 organ(s), highest expression level in adrenal tissue

CleanEx database of gene expression profiles

More...
CleanExi
HS_SRXN1

Genevisible search portal to normalized and curated expression data from Genevestigator

More...
Genevisiblei
Q9BYN0 HS

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

<p>This subsection of the '<a href="http://www.uniprot.org/help/interaction_section%27">Interaction</a> section provides information about binary protein-protein interactions. The data presented in this section are a quality-filtered subset of binary interactions automatically derived from the <a href="http://www.ebi.ac.uk/intact/">IntAct database</a>. It is updated on a monthly basis. Each binary interaction is displayed on a separate line.<p><a href='/help/binary_interactions' target='_top'>More...</a></p>Binary interactionsi

WithEntry#Exp.IntActNotes
PRDX1Q068303EBI-15678820,EBI-353193

Protein-protein interaction databases

The Biological General Repository for Interaction Datasets (BioGrid)

More...
BioGridi
126716, 39 interactors

CORUM comprehensive resource of mammalian protein complexes

More...
CORUMi
Q9BYN0

Database of interacting proteins

More...
DIPi
DIP-59836N

Protein interaction database and analysis system

More...
IntActi
Q9BYN0, 1 interactor

STRING: functional protein association networks

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STRINGi
9606.ENSP00000371388

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

Secondary structure

1137
Legend: HelixTurnBeta strandPDB Structure known for this area
Show more details

3D structure databases

Select the link destinations:

Protein Data Bank Europe

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PDBei

Protein Data Bank RCSB

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RCSB PDBi

Protein Data Bank Japan

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PDBji
Links Updated
PDB entryMethodResolution (Å)ChainPositionsPDBsum
1XW3X-ray1.65A32-137[»]
1XW4X-ray2.00X32-137[»]
1YZSNMR-A17-137[»]
2B6FNMR-A17-137[»]
2RIIX-ray2.60X/Y32-137[»]
3CYIX-ray1.80A32-137[»]
3HY2X-ray2.10X/Y32-137[»]

Protein Model Portal of the PSI-Nature Structural Biology Knowledgebase

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ProteinModelPortali
Q9BYN0

SWISS-MODEL Repository - a database of annotated 3D protein structure models

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SMRi
Q9BYN0

Database of comparative protein structure models

More...
ModBasei
Search...

MobiDB: a database of protein disorder and mobility annotations

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MobiDBi
Search...

Miscellaneous databases

Relative evolutionary importance of amino acids within a protein sequence

More...
EvolutionaryTracei
Q9BYN0

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

<p>This subsection of the ‘Family and domains’ section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Belongs to the sulfiredoxin family.Curated

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
KOG3388 Eukaryota
COG5119 LUCA

Ensembl GeneTree

More...
GeneTreei
ENSGT00390000007832

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...
HOGENOMi
HOG000231799

The HOVERGEN Database of Homologous Vertebrate Genes

More...
HOVERGENi
HBG080441

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
Q9BYN0

KEGG Orthology (KO)

More...
KOi
K12260

Identification of Orthologs from Complete Genome Data

More...
OMAi
GGCHRFA

Database of Orthologous Groups

More...
OrthoDBi
1421270at2759

Database for complete collections of gene phylogenies

More...
PhylomeDBi
Q9BYN0

TreeFam database of animal gene trees

More...
TreeFami
TF300230

Family and domain databases

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR003115 ParB/Sulfiredoxin_dom
IPR036086 ParB/Sulfiredoxin_sf
IPR016692 Sulfiredoxin

The PANTHER Classification System

More...
PANTHERi
PTHR21348 PTHR21348, 1 hit

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF02195 ParBc, 1 hit

PIRSF; a whole-protein classification database

More...
PIRSFi
PIRSF017267 Sulfiredoxin, 1 hit

Simple Modular Architecture Research Tool; a protein domain database

More...
SMARTi
View protein in SMART
SM00470 ParB, 1 hit

Superfamily database of structural and functional annotation

More...
SUPFAMi
SSF110849 SSF110849, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>.<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

Q9BYN0-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MGLRAGGTLG RAGAGRGAPE GPGPSGGAQG GSIHSGRIAA VHNVPLSVLI
60 70 80 90 100
RPLPSVLDPA KVQSLVDTIR EDPDSVPPID VLWIKGAQGG DYFYSFGGCH
110 120 130
RYAAYQQLQR ETIPAKLVQS TLSDLRVYLG ASTPDLQ
Length:137
Mass (Da):14,259
Last modified:April 30, 2003 - v2
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i44F2C4256E5574D0
GO

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

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EMBLi

GenBank nucleotide sequence database

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GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
AK312054 mRNA Translation: BAG34990.1
AL833944 mRNA Translation: CAD38799.1
AL121758 Genomic DNA No translation available.
BC017001 mRNA Translation: AAH17001.1
BC032604 mRNA Translation: AAH32604.1
BC047707 mRNA Translation: AAH47707.1

The Consensus CDS (CCDS) project

More...
CCDSi
CCDS13005.1

NCBI Reference Sequences

More...
RefSeqi
NP_542763.1, NM_080725.2

UniGene gene-oriented nucleotide sequence clusters

More...
UniGenei
Hs.516830

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...
Ensembli
ENST00000381962; ENSP00000371388; ENSG00000271303

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
140809

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
hsa:140809

UCSC genome browser

More...
UCSCi
uc002wea.5 human

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

<p>This subsection of the <a href="http://www.uniprot.org/manual/cross_references_section">Cross-references</a> section provides links to various web resources that are relevant for a specific protein.<p><a href='/help/web_resource' target='_top'>More...</a></p>Web resourcesi

Atlas of Genetics and Cytogenetics in Oncology and Haematology

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK312054 mRNA Translation: BAG34990.1
AL833944 mRNA Translation: CAD38799.1
AL121758 Genomic DNA No translation available.
BC017001 mRNA Translation: AAH17001.1
BC032604 mRNA Translation: AAH32604.1
BC047707 mRNA Translation: AAH47707.1
CCDSiCCDS13005.1
RefSeqiNP_542763.1, NM_080725.2
UniGeneiHs.516830

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
PDB entryMethodResolution (Å)ChainPositionsPDBsum
1XW3X-ray1.65A32-137[»]
1XW4X-ray2.00X32-137[»]
1YZSNMR-A17-137[»]
2B6FNMR-A17-137[»]
2RIIX-ray2.60X/Y32-137[»]
3CYIX-ray1.80A32-137[»]
3HY2X-ray2.10X/Y32-137[»]
ProteinModelPortaliQ9BYN0
SMRiQ9BYN0
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi126716, 39 interactors
CORUMiQ9BYN0
DIPiDIP-59836N
IntActiQ9BYN0, 1 interactor
STRINGi9606.ENSP00000371388

PTM databases

iPTMnetiQ9BYN0
PhosphoSitePlusiQ9BYN0

Polymorphism and mutation databases

BioMutaiSRXN1
DMDMi30315944

Proteomic databases

EPDiQ9BYN0
jPOSTiQ9BYN0
MaxQBiQ9BYN0
PaxDbiQ9BYN0
PeptideAtlasiQ9BYN0
PRIDEiQ9BYN0
ProteomicsDBi79670

Protocols and materials databases

The DNASU plasmid repository

More...
DNASUi
140809
Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENST00000381962; ENSP00000371388; ENSG00000271303
GeneIDi140809
KEGGihsa:140809
UCSCiuc002wea.5 human

Organism-specific databases

Comparative Toxicogenomics Database

More...
CTDi
140809
DisGeNETi140809
EuPathDBiHostDB:ENSG00000271303.1

GeneCards: human genes, protein and diseases

More...
GeneCardsi
SRXN1
HGNCiHGNC:16132 SRXN1
MIMi617583 gene
neXtProtiNX_Q9BYN0
OpenTargetsiENSG00000271303
PharmGKBiPA25681

GenAtlas: human gene database

More...
GenAtlasi
Search...

Phylogenomic databases

eggNOGiKOG3388 Eukaryota
COG5119 LUCA
GeneTreeiENSGT00390000007832
HOGENOMiHOG000231799
HOVERGENiHBG080441
InParanoidiQ9BYN0
KOiK12260
OMAiGGCHRFA
OrthoDBi1421270at2759
PhylomeDBiQ9BYN0
TreeFamiTF300230

Enzyme and pathway databases

BRENDAi1.8.98.2 2681

Miscellaneous databases

ChiTaRS: a database of human, mouse and fruit fly chimeric transcripts and RNA-sequencing data

More...
ChiTaRSi
SRXN1 human
EvolutionaryTraceiQ9BYN0

The Gene Wiki collection of pages on human genes and proteins

More...
GeneWikii
SRXN1

Database of phenotypes from RNA interference screens in Drosophila and Homo sapiens

More...
GenomeRNAii
140809

Protein Ontology

More...
PROi
PR:Q9BYN0

The Stanford Online Universal Resource for Clones and ESTs

More...
SOURCEi
Search...

Gene expression databases

BgeeiENSG00000271303 Expressed in 94 organ(s), highest expression level in adrenal tissue
CleanExiHS_SRXN1
GenevisibleiQ9BYN0 HS

Family and domain databases

InterProiView protein in InterPro
IPR003115 ParB/Sulfiredoxin_dom
IPR036086 ParB/Sulfiredoxin_sf
IPR016692 Sulfiredoxin
PANTHERiPTHR21348 PTHR21348, 1 hit
PfamiView protein in Pfam
PF02195 ParBc, 1 hit
PIRSFiPIRSF017267 Sulfiredoxin, 1 hit
SMARTiView protein in SMART
SM00470 ParB, 1 hit
SUPFAMiSSF110849 SSF110849, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

More...
ProtoNeti
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the ‘Entry information’ section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiSRXN1_HUMAN
<p>This subsection of the ‘Entry information’ section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called ‘Primary (citable) accession number’.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q9BYN0
Secondary accession number(s): B2R543, Q8NDM3, Q96AK6
<p>This subsection of the ‘Entry information’ section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification (‘Last modified’). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: April 30, 2003
Last sequence update: April 30, 2003
Last modified: January 16, 2019
This is version 148 of the entry and version 2 of the sequence. See complete history.
<p>This subsection of the ‘Entry information’ section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

3D-structure, Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families
  2. MIM cross-references
    Online Mendelian Inheritance in Man (MIM) cross-references in UniProtKB/Swiss-Prot
  3. PDB cross-references
    Index of Protein Data Bank (PDB) cross-references
  4. Human chromosome 20
    Human chromosome 20: entries, gene names and cross-references to MIM
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