UniProtKB - Q9BY07 (S4A5_HUMAN)
Electrogenic sodium bicarbonate cotransporter 4
SLC4A5
Functioni
Mediates sodium- and bicarbonate-dependent electrogenic sodium bicarbonate cotransport, with a Na+:HCO3- stoichiometry of 2:1. May have a housekeeping function in regulating the pH of tissues in which it is expressed. May play a role in mediating Na+:HCO3- cotransport in hepatocytes and intrahepatic cholangiocytes. Also may be important in protecting the renal paranchyma from alterations in urine pH.
By similarity3 PublicationsActivity regulationi
GO - Molecular functioni
- anion:anion antiporter activity Source: UniProtKB-KW
- inorganic anion exchanger activity Source: InterPro
- sodium:bicarbonate symporter activity Source: GO_Central
- transmembrane transporter activity Source: GO_Central
GO - Biological processi
- bicarbonate transport Source: GO_Central
- cerebrospinal fluid secretion Source: Ensembl
- epithelial cell development Source: Ensembl
- ion homeostasis Source: GO_Central
- mitochondrion distribution Source: Ensembl
- regulation of gene expression Source: Ensembl
- regulation of intracellular pH Source: GO_Central
- regulation of systemic arterial blood pressure Source: Ensembl
- renal system process Source: GO_Central
- retina development in camera-type eye Source: Ensembl
- transmembrane transport Source: GO_Central
Keywordsi
Biological process | Anion exchange, Ion transport, Sodium transport, Transport |
Ligand | Sodium |
Enzyme and pathway databases
PathwayCommonsi | Q9BY07 |
Reactomei | R-HSA-425381, Bicarbonate transporters |
SignaLinki | Q9BY07 |
Protein family/group databases
TCDBi | 2.A.31.2.17, the anion exchanger (ae) family 2.A.31.2.8, the anion exchanger (ae) family |
Names & Taxonomyi
Protein namesi | Recommended name: Electrogenic sodium bicarbonate cotransporter 4Alternative name(s): NBCe2 Solute carrier family 4 member 5 |
Gene namesi | |
Organismi | Homo sapiens (Human) |
Taxonomic identifieri | 9606 [NCBI] |
Taxonomic lineagei | Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Primates › Haplorrhini › Catarrhini › Hominidae › Homo |
Proteomesi |
|
Organism-specific databases
HGNCi | HGNC:18168, SLC4A5 |
MIMi | 606757, gene |
neXtProti | NX_Q9BY07 |
VEuPathDBi | HostDB:ENSG00000188687 |
Subcellular locationi
Plasma membrane
- Apical cell membrane 1 Publication; Multi-pass membrane protein 1 Publication
Note: Expressed in the apical plasma membrane domain of a subset of collecting ducts in the renal medulla.1 Publication
Plasma Membrane
- apical plasma membrane Source: ARUK-UCL
- plasma membrane Source: GO_Central
Other locations
- integral component of membrane Source: UniProtKB
Topology
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Topological domaini | 1 – 521 | CytoplasmicSequence analysisAdd BLAST | 521 | |
Transmembranei | 522 – 544 | HelicalSequence analysisAdd BLAST | 23 | |
Topological domaini | 545 – 555 | ExtracellularSequence analysisAdd BLAST | 11 | |
Transmembranei | 556 – 587 | HelicalSequence analysisAdd BLAST | 32 | |
Topological domaini | 588 – 606 | CytoplasmicSequence analysisAdd BLAST | 19 | |
Transmembranei | 607 – 628 | HelicalSequence analysisAdd BLAST | 22 | |
Topological domaini | 629 – 742 | ExtracellularSequence analysisAdd BLAST | 114 | |
Transmembranei | 743 – 762 | HelicalSequence analysisAdd BLAST | 20 | |
Topological domaini | 763 – 773 | CytoplasmicSequence analysisAdd BLAST | 11 | |
Transmembranei | 774 – 795 | HelicalSequence analysisAdd BLAST | 22 | |
Topological domaini | 796 – 828 | ExtracellularSequence analysisAdd BLAST | 33 | |
Transmembranei | 829 – 847 | HelicalSequence analysisAdd BLAST | 19 | |
Topological domaini | 848 – 866 | CytoplasmicSequence analysisAdd BLAST | 19 | |
Transmembranei | 867 – 883 | HelicalSequence analysisAdd BLAST | 17 | |
Topological domaini | 884 – 888 | ExtracellularSequence analysis | 5 | |
Transmembranei | 889 – 908 | HelicalSequence analysisAdd BLAST | 20 | |
Topological domaini | 909 – 928 | CytoplasmicSequence analysisAdd BLAST | 20 | |
Transmembranei | 929 – 948 | HelicalSequence analysisAdd BLAST | 20 | |
Topological domaini | 949 – 953 | ExtracellularSequence analysis | 5 | |
Transmembranei | 954 – 971 | HelicalSequence analysisAdd BLAST | 18 | |
Topological domaini | 972 – 1016 | CytoplasmicSequence analysisAdd BLAST | 45 | |
Transmembranei | 1017 – 1034 | HelicalSequence analysisAdd BLAST | 18 | |
Topological domaini | 1035 – 1039 | ExtracellularSequence analysis | 5 | |
Transmembranei | 1040 – 1057 | HelicalSequence analysisAdd BLAST | 18 | |
Topological domaini | 1058 – 1137 | CytoplasmicSequence analysisAdd BLAST | 80 |
Keywords - Cellular componenti
Cell membrane, MembranePathology & Biotechi
Organism-specific databases
DisGeNETi | 57835 |
OpenTargetsi | ENSG00000188687 |
PharmGKBi | PA164742397 |
Miscellaneous databases
Pharosi | Q9BY07, Tbio |
Chemistry databases
DrugBanki | DB01390, Sodium bicarbonate |
Genetic variation databases
BioMutai | SLC4A5 |
DMDMi | 182691595 |
PTM / Processingi
Molecule processing
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
ChainiPRO_0000328920 | 1 – 1137 | Electrogenic sodium bicarbonate cotransporter 4Add BLAST | 1137 |
Amino acid modifications
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Disulfide bondi | 679 ↔ 681 | By similarity | ||
Disulfide bondi | 725 ↔ 737 | By similarity |
Keywords - PTMi
Disulfide bondProteomic databases
MassIVEi | Q9BY07 |
MaxQBi | Q9BY07 |
PaxDbi | Q9BY07 |
PeptideAtlasi | Q9BY07 |
PRIDEi | Q9BY07 |
ProteomicsDBi | 79546 [Q9BY07-1] 79547 [Q9BY07-2] 79548 [Q9BY07-3] 79549 [Q9BY07-4] 79550 [Q9BY07-5] 79551 [Q9BY07-6] 79552 [Q9BY07-7] 79553 [Q9BY07-8] |
PTM databases
GlyConnecti | 2038, 1 N-Linked glycan (1 site) |
GlyGeni | Q9BY07, 1 site, 2 N-linked glycans (1 site) |
iPTMneti | Q9BY07 |
PhosphoSitePlusi | Q9BY07 |
Expressioni
Tissue specificityi
Gene expression databases
Bgeei | ENSG00000188687, Expressed in sural nerve and 117 other tissues |
ExpressionAtlasi | Q9BY07, baseline and differential |
Genevisiblei | Q9BY07, HS |
Organism-specific databases
HPAi | ENSG00000188687, Tissue enhanced (choroid plexus, retina, thyroid gland) |
Interactioni
Protein-protein interaction databases
BioGRIDi | 121791, 3 interactors |
IntActi | Q9BY07, 2 interactors |
MINTi | Q9BY07 |
STRINGi | 9606.ENSP00000251768 |
Miscellaneous databases
RNActi | Q9BY07, protein |
Family & Domainsi
Region
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Regioni | 1 – 52 | DisorderedSequence analysisAdd BLAST | 52 | |
Regioni | 64 – 94 | DisorderedSequence analysisAdd BLAST | 31 | |
Regioni | 221 – 255 | DisorderedSequence analysisAdd BLAST | 35 | |
Regioni | 438 – 478 | DisorderedSequence analysisAdd BLAST | 41 | |
Regioni | 1079 – 1137 | DisorderedSequence analysisAdd BLAST | 59 |
Compositional bias
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Compositional biasi | 1 – 27 | Basic and acidic residuesSequence analysisAdd BLAST | 27 | |
Compositional biasi | 68 – 94 | Polar residuesSequence analysisAdd BLAST | 27 | |
Compositional biasi | 231 – 245 | Polar residuesSequence analysisAdd BLAST | 15 | |
Compositional biasi | 1079 – 1099 | Basic and acidic residuesSequence analysisAdd BLAST | 21 | |
Compositional biasi | 1112 – 1137 | Polar residuesSequence analysisAdd BLAST | 26 |
Sequence similaritiesi
Keywords - Domaini
Transmembrane, Transmembrane helixPhylogenomic databases
eggNOGi | KOG1172, Eukaryota |
GeneTreei | ENSGT00940000157488 |
HOGENOMi | CLU_002289_5_0_1 |
InParanoidi | Q9BY07 |
OMAi | WIPSDFY |
OrthoDBi | 265068at2759 |
PhylomeDBi | Q9BY07 |
TreeFami | TF313630 |
Family and domain databases
Gene3Di | 3.40.930.10, 1 hit |
InterProi | View protein in InterPro IPR013769, Band3_cytoplasmic_dom IPR011531, HCO3_transpt-like_TM_dom IPR003020, HCO3_transpt_euk IPR003024, Na/HCO3_transpt IPR016152, PTrfase/Anion_transptr |
PANTHERi | PTHR11453, PTHR11453, 1 hit |
Pfami | View protein in Pfam PF07565, Band_3_cyto, 1 hit PF00955, HCO3_cotransp, 1 hit |
PRINTSi | PR01231, HCO3TRNSPORT PR01232, NAHCO3TRSPRT |
SUPFAMi | SSF55804, SSF55804, 1 hit |
TIGRFAMsi | TIGR00834, ae, 1 hit |
s (8+)i Sequence
Sequence statusi: Complete.
This entry describes 8 produced by isoformsialternative splicing. AlignAdd to basketThis entry has 8 described isoforms and 6 potential isoforms that are computationally mapped.Show allAlign All
This isoform has been chosen as the sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry. canonicali
10 20 30 40 50
MKVKEEKAGV GKLDHTNHRR RFPDQKECPP IHIGLPVPTY PQRKTDQKGH
60 70 80 90 100
LSGLQKVHWG LRPDQPQQEL TGPGSGASSQ DSSMDLISRT RSPAAEQLQD
110 120 130 140 150
ILGEEDEAPN PTLFTEMDTL QHDGDQMEWK ESARWIKFEE KVEEGGERWS
160 170 180 190 200
KPHVSTLSLH SLFELRTCLQ TGTVLLDLDS GSLPQIIDDV IEKQIEDGLL
210 220 230 240 250
RPELRERVSY VLLRRHRHQT KKPIHRSLAD IGKSVSTTNR SPARSPGAGP
260 270 280 290 300
SLHHSTEDLR MRQSANYGRL CHAQSRSMND ISLTPNTDQR KNKFMKKIPK
310 320 330 340 350
DSEASNVLVG EVDFLDQPFI AFVRLIQSAM LGGVTEVPVP TRFLFILLGP
360 370 380 390 400
SGRAKSYNEI GRAIATLMVD DLFSDVAYKA RNREDLIAGI DEFLDEVIVL
410 420 430 440 450
PPGEWDPNIR IEPPKKVPSA DKRKSVFSLA ELGQMNGSVG GGGGAPGGGN
460 470 480 490 500
GGGGGGGSGG GAGSGGAGGT SSGDDGEMPA MHEIGEELIW TGRFFGGLCL
510 520 530 540 550
DIKRKLPWFP SDFYDGFHIQ SISAILFIYL GCITNAITFG GLLGDATDNY
560 570 580 590 600
QGVMESFLGT AMAGSLFCLF SGQPLIILSS TGPILIFEKL LFDFSKGNGL
610 620 630 640 650
DYMEFRLWIG LHSAVQCLIL VATDASFIIK YITRFTEEGF STLISFIFIY
660 670 680 690 700
DAIKKMIGAF KYYPINMDFK PNFITTYKCE CVAPDTVNTT VFNASAPLAP
710 720 730 740 750
DTNASLYNLL NLTALDWSLL SKKECLSYGG RLLGNSCKFI PDLALMSFIL
760 770 780 790 800
FFGTYSMTLT LKKFKFSRYF PTKVRALVAD FSIVFSILMF CGIDACFGLE
810 820 830 840 850
TPKLHVPSVI KPTRPDRGWF VAPFGKNPWW VYPASILPAL LVTILIFMDQ
860 870 880 890 900
QITAVIVNRK ENKLKKAAGY HLDLFWVGIL MALCSFMGLP WYVAATVISI
910 920 930 940 950
AHIDSLKMET ETSAPGEQPQ FLGVREQRVT GIIVFILTGI SVFLAPILKC
960 970 980 990 1000
IPLPVLYGVF LYMGVASLNG IQMGTGGSEF KIQKKLTPFW ERCKLFLMPA
1010 1020 1030 1040 1050
KHQPDHAFLR HVPLRRIHLF TLVQILCLAV LWILKSTVAA IIFPVMILGL
1060 1070 1080 1090 1100
IIVRRLLDFI FSQHDLAWID NILPEKEKKE TDKKRKRKKG AHEDCDEEPQ
1110 1120 1130
FPPPSVIKIP MESVQSDPQN GIHCIARKRS SSWSYSL
The sequence of this isoform differs from the canonical sequence as follows:
88-91: SRTR → EHKG
866-993: KAAGYHLDLF...KKLTPFWERC → GTESNRHHRL...HLFPARPGLD
994-1137: Missing.
The sequence of this isoform differs from the canonical sequence as follows:
774-811: Missing.
866-924: Missing.
973-988: Missing.
1046-1046: M → MSLSTTD
1071-1075: NILPE → KIEFP
1076-1137: Missing.
Computationally mapped potential isoform sequencesi
There are 6 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basketE7EQT3 | E7EQT3_HUMAN | Anion exchange protein | SLC4A5 hCG_1988260 | 998 | Annotation score: | ||
A0A1B0GVY3 | A0A1B0GVY3_HUMAN | Electrogenic sodium bicarbonate cot... | SLC4A5 | 210 | Annotation score: | ||
C9JU12 | C9JU12_HUMAN | Electrogenic sodium bicarbonate cot... | SLC4A5 | 144 | Annotation score: | ||
C9JW32 | C9JW32_HUMAN | Electrogenic sodium bicarbonate cot... | SLC4A5 | 129 | Annotation score: | ||
C9JNL6 | C9JNL6_HUMAN | Electrogenic sodium bicarbonate cot... | SLC4A5 | 122 | Annotation score: | ||
A0A1B0GUV9 | A0A1B0GUV9_HUMAN | Electrogenic sodium bicarbonate cot... | SLC4A5 | 71 | Annotation score: |
Sequence cautioni
Experimental Info
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Sequence conflicti | 612 | H → Y in AAL48291 (PubMed:12388414).Curated | 1 | |
Sequence conflicti | 612 | H → Y in AAL50802 (PubMed:12388414).Curated | 1 | |
Sequence conflicti | 699 | A → T in AAL48291 (PubMed:12388414).Curated | 1 | |
Sequence conflicti | 759 | L → R in AAL50802 (PubMed:12388414).Curated | 1 | |
Sequence conflicti | 813 | T → P in AAK26741 (PubMed:11087115).Curated | 1 | |
Sequence conflicti | 896 | T → M in AAL48291 (PubMed:12388414).Curated | 1 | |
Sequence conflicti | 923 | G → R in AAL48291 (PubMed:12388414).Curated | 1 |
Natural variant
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Natural variantiVAR_048350 | 251 | S → N. Corresponds to variant dbSNP:rs17009792Ensembl. | 1 | |
Natural variantiVAR_061032 | 253 | H → Y1 PublicationCorresponds to variant dbSNP:rs55651232Ensembl. | 1 |
Alternative sequence
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Alternative sequenceiVSP_052770 | 27 – 91 | ECPPI…ISRTR → G in isoform 7. 1 PublicationAdd BLAST | 65 | |
Alternative sequenceiVSP_052771 | 88 – 91 | SRTR → EHKG in isoform 5. 1 Publication | 4 | |
Alternative sequenceiVSP_052772 | 774 – 811 | Missing in isoform 6 and isoform 7. 2 PublicationsAdd BLAST | 38 | |
Alternative sequenceiVSP_052773 | 866 – 993 | KAAGY…FWERC → GTESNRHHRLHPDGNLCLPG SHPKVYPPAGAVRSLPLHGR GLPEWHPVLGTLQALPDASQ APAGPCLPAARAAAPDPPLH PGADPLPGGALDPQIHGGCH HLPGHDPGPHHRSKASGFHL FPARPGLD in isoform 5. 1 PublicationAdd BLAST | 128 | |
Alternative sequenceiVSP_052774 | 866 – 924 | Missing in isoform 6. 1 PublicationAdd BLAST | 59 | |
Alternative sequenceiVSP_052775 | 950 – 1046 | Missing in isoform 4. 1 PublicationAdd BLAST | 97 | |
Alternative sequenceiVSP_052776 | 973 – 988 | Missing in isoform 3, isoform 6 and isoform 7. 4 PublicationsAdd BLAST | 16 | |
Alternative sequenceiVSP_052777 | 994 – 1137 | Missing in isoform 5. 1 PublicationAdd BLAST | 144 | |
Alternative sequenceiVSP_052778 | 1046 | M → MSLSTTD in isoform 2 and isoform 6. 3 Publications | 1 | |
Alternative sequenceiVSP_052779 | 1068 – 1137 | Missing in isoform 8. 1 PublicationAdd BLAST | 70 | |
Alternative sequenceiVSP_052780 | 1071 – 1075 | NILPE → KIEFP in isoform 6. 1 Publication | 5 | |
Alternative sequenceiVSP_052781 | 1076 – 1137 | Missing in isoform 6. 1 PublicationAdd BLAST | 62 |
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AF207661 mRNA Translation: AAG18492.1 Frameshift. AF243499 mRNA Translation: AAK26741.1 AF293338 mRNA Translation: AAK97073.1 AF293337 mRNA Translation: AAK97072.1 AF452248 mRNA Translation: AAL48291.1 AF453528 mRNA Translation: AAL50802.1 Frameshift. CH471053 Genomic DNA Translation: EAW99690.1 CH471053 Genomic DNA Translation: EAW99691.1 Frameshift. CH471053 Genomic DNA Translation: EAW99693.1 BC109221 mRNA Translation: AAI09222.1 AB209752 mRNA Translation: BAD92989.1 |
CCDSi | CCDS1936.1 [Q9BY07-1] CCDS1937.1 [Q9BY07-3] |
RefSeqi | NP_067019.3, NM_021196.3 [Q9BY07-1] NP_597812.1, NM_133478.2 [Q9BY07-3] |
Genome annotation databases
Keywords - Coding sequence diversityi
Alternative splicingSimilar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AF207661 mRNA Translation: AAG18492.1 Frameshift. AF243499 mRNA Translation: AAK26741.1 AF293338 mRNA Translation: AAK97073.1 AF293337 mRNA Translation: AAK97072.1 AF452248 mRNA Translation: AAL48291.1 AF453528 mRNA Translation: AAL50802.1 Frameshift. CH471053 Genomic DNA Translation: EAW99690.1 CH471053 Genomic DNA Translation: EAW99691.1 Frameshift. CH471053 Genomic DNA Translation: EAW99693.1 BC109221 mRNA Translation: AAI09222.1 AB209752 mRNA Translation: BAD92989.1 |
CCDSi | CCDS1936.1 [Q9BY07-1] CCDS1937.1 [Q9BY07-3] |
RefSeqi | NP_067019.3, NM_021196.3 [Q9BY07-1] NP_597812.1, NM_133478.2 [Q9BY07-3] |
3D structure databases
AlphaFoldDBi | Q9BY07 |
SMRi | Q9BY07 |
ModBasei | Search... |
Protein-protein interaction databases
BioGRIDi | 121791, 3 interactors |
IntActi | Q9BY07, 2 interactors |
MINTi | Q9BY07 |
STRINGi | 9606.ENSP00000251768 |
Chemistry databases
DrugBanki | DB01390, Sodium bicarbonate |
Protein family/group databases
TCDBi | 2.A.31.2.17, the anion exchanger (ae) family 2.A.31.2.8, the anion exchanger (ae) family |
PTM databases
GlyConnecti | 2038, 1 N-Linked glycan (1 site) |
GlyGeni | Q9BY07, 1 site, 2 N-linked glycans (1 site) |
iPTMneti | Q9BY07 |
PhosphoSitePlusi | Q9BY07 |
Genetic variation databases
BioMutai | SLC4A5 |
DMDMi | 182691595 |
Proteomic databases
MassIVEi | Q9BY07 |
MaxQBi | Q9BY07 |
PaxDbi | Q9BY07 |
PeptideAtlasi | Q9BY07 |
PRIDEi | Q9BY07 |
ProteomicsDBi | 79546 [Q9BY07-1] 79547 [Q9BY07-2] 79548 [Q9BY07-3] 79549 [Q9BY07-4] 79550 [Q9BY07-5] 79551 [Q9BY07-6] 79552 [Q9BY07-7] 79553 [Q9BY07-8] |
Protocols and materials databases
Antibodypediai | 47475, 73 antibodies from 17 providers |
DNASUi | 57835 |
Genome annotation databases
Organism-specific databases
CTDi | 57835 |
DisGeNETi | 57835 |
GeneCardsi | SLC4A5 |
HGNCi | HGNC:18168, SLC4A5 |
HPAi | ENSG00000188687, Tissue enhanced (choroid plexus, retina, thyroid gland) |
MIMi | 606757, gene |
neXtProti | NX_Q9BY07 |
OpenTargetsi | ENSG00000188687 |
PharmGKBi | PA164742397 |
VEuPathDBi | HostDB:ENSG00000188687 |
GenAtlasi | Search... |
Phylogenomic databases
eggNOGi | KOG1172, Eukaryota |
GeneTreei | ENSGT00940000157488 |
HOGENOMi | CLU_002289_5_0_1 |
InParanoidi | Q9BY07 |
OMAi | WIPSDFY |
OrthoDBi | 265068at2759 |
PhylomeDBi | Q9BY07 |
TreeFami | TF313630 |
Enzyme and pathway databases
PathwayCommonsi | Q9BY07 |
Reactomei | R-HSA-425381, Bicarbonate transporters |
SignaLinki | Q9BY07 |
Miscellaneous databases
BioGRID-ORCSi | 57835, 105 hits in 1074 CRISPR screens |
ChiTaRSi | SLC4A5, human |
GeneWikii | SLC4A5 |
GenomeRNAii | 57835 |
Pharosi | Q9BY07, Tbio |
PROi | PR:Q9BY07 |
RNActi | Q9BY07, protein |
SOURCEi | Search... |
Gene expression databases
Bgeei | ENSG00000188687, Expressed in sural nerve and 117 other tissues |
ExpressionAtlasi | Q9BY07, baseline and differential |
Genevisiblei | Q9BY07, HS |
Family and domain databases
Gene3Di | 3.40.930.10, 1 hit |
InterProi | View protein in InterPro IPR013769, Band3_cytoplasmic_dom IPR011531, HCO3_transpt-like_TM_dom IPR003020, HCO3_transpt_euk IPR003024, Na/HCO3_transpt IPR016152, PTrfase/Anion_transptr |
PANTHERi | PTHR11453, PTHR11453, 1 hit |
Pfami | View protein in Pfam PF07565, Band_3_cyto, 1 hit PF00955, HCO3_cotransp, 1 hit |
PRINTSi | PR01231, HCO3TRNSPORT PR01232, NAHCO3TRSPRT |
SUPFAMi | SSF55804, SSF55804, 1 hit |
TIGRFAMsi | TIGR00834, ae, 1 hit |
MobiDBi | Search... |
Entry informationi
Entry namei | S4A5_HUMAN | |
Accessioni | Q9BY07Primary (citable) accession number: Q9BY07 Secondary accession number(s): Q32MA7 Q9HBU5 | |
Entry historyi | Integrated into UniProtKB/Swiss-Prot: | April 8, 2008 |
Last sequence update: | April 8, 2008 | |
Last modified: | May 25, 2022 | |
This is version 154 of the entry and version 2 of the sequence. See complete history. | ||
Entry statusi | Reviewed (UniProtKB/Swiss-Prot) | |
Annotation program | Chordata Protein Annotation Program | |
Disclaimer | Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care. |
Miscellaneousi
Keywords - Technical termi
Reference proteomeDocuments
- Human chromosome 2
Human chromosome 2: entries, gene names and cross-references to MIM - Human entries with genetic variants
List of human entries with genetic variants - Human variants curated from literature reports
Index of human variants curated from literature reports - MIM cross-references
Online Mendelian Inheritance in Man (MIM) cross-references in UniProtKB/Swiss-Prot - SIMILARITY comments
Index of protein domains and families