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Entry version 149 (10 Feb 2021)
Sequence version 1 (01 Jun 2001)
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Protein

Ubiquitin carboxyl-terminal hydrolase 26

Gene

USP26

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score:

Annotation score:5 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Involved in the ubiquitin-dependent proteolytic pathway in conjunction with the 26S proteasome (By similarity). Deubiquitinates the androgen receptor and regulates the androgen receptor signaling pathway.By similarity1 Publication

<p>This subsection of the <a href="http://www.uniprot.org/help/function%5Fsection">Function</a> section describes the catalytic activity of an enzyme, i.e. a chemical reaction that the enzyme catalyzes.<p><a href='/help/catalytic_activity' target='_top'>More...</a></p>Catalytic activityi

  • Thiol-dependent hydrolysis of ester, thioester, amide, peptide and isopeptide bonds formed by the C-terminal Gly of ubiquitin (a 76-residue protein attached to proteins as an intracellular targeting signal). EC:3.4.19.12

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/function%5Fsection">Function</a> section is used for enzymes and indicates the residues directly involved in catalysis.<p><a href='/help/act_site' target='_top'>More...</a></p>Active sitei304NucleophilePROSITE-ProRule annotation1
Active sitei841Proton acceptorPROSITE-ProRule annotation1

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

GO - Biological processi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Molecular functionHydrolase, Protease, Thiol protease
Biological processUbl conjugation pathway

Enzyme and pathway databases

Pathway Commons web resource for biological pathway data

More...
PathwayCommonsi
Q9BXU7

Reactome - a knowledgebase of biological pathways and processes

More...
Reactomei
R-HSA-5689880, Ub-specific processing proteases

Protein family/group databases

MEROPS protease database

More...
MEROPSi
C19.046

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Ubiquitin carboxyl-terminal hydrolase 26 (EC:3.4.19.12)
Alternative name(s):
Deubiquitinating enzyme 26
Ubiquitin thioesterase 26
Ubiquitin-specific-processing protease 26
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:USP26
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiHomo sapiens (Human)
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri9606 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000005640 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome X

Organism-specific databases

Human Gene Nomenclature Database

More...
HGNCi
HGNC:13485, USP26

Online Mendelian Inheritance in Man (OMIM)

More...
MIMi
300309, gene

neXtProt; the human protein knowledge platform

More...
neXtProti
NX_Q9BXU7

Eukaryotic Pathogen, Vector and Host Database Resources

More...
VEuPathDBi
HostDB:ENSG00000134588.12

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte & Seán O’Donoghue; Source: COMPARTMENTS

Keywords - Cellular componenti

Nucleus

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

Mutagenesis

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/manual/pathology%5Fand%5Fbiotech%5Fsection">'Pathology and Biotech'</a> section describes the effect of the experimental mutation of one or more amino acid(s) on the biological properties of the protein.<p><a href='/help/mutagen' target='_top'>More...</a></p>Mutagenesisi304C → S: Results in increased AR signaling. 1 Publication1

Organism-specific databases

DisGeNET

More...
DisGeNETi
83844

Open Targets

More...
OpenTargetsi
ENSG00000134588

The Pharmacogenetics and Pharmacogenomics Knowledge Base

More...
PharmGKBi
PA37782

Miscellaneous databases

Pharos NIH Druggable Genome Knowledgebase

More...
Pharosi
Q9BXU7, Tbio

Genetic variation databases

BioMuta curated single-nucleotide variation and disease association database

More...
BioMutai
USP26

Domain mapping of disease mutations (DMDM)

More...
DMDMi
18202739

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'PTM / Processing' section describes the extent of a polypeptide chain in the mature protein following processing or proteolytic cleavage.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00000806551 – 913Ubiquitin carboxyl-terminal hydrolase 26Add BLAST913

Proteomic databases

PaxDb, a database of protein abundance averages across all three domains of life

More...
PaxDbi
Q9BXU7

PeptideAtlas

More...
PeptideAtlasi
Q9BXU7

PRoteomics IDEntifications database

More...
PRIDEi
Q9BXU7

ProteomicsDB: a multi-organism proteome resource

More...
ProteomicsDBi
79521

PTM databases

iPTMnet integrated resource for PTMs in systems biology context

More...
iPTMneti
Q9BXU7

Comprehensive resource for the study of protein post-translational modifications (PTMs) in human, mouse and rat.

More...
PhosphoSitePlusi
Q9BXU7

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...
Bgeei
ENSG00000134588, Expressed in muscle tissue and 25 other tissues

Genevisible search portal to normalized and curated expression data from Genevestigator

More...
Genevisiblei
Q9BXU7, HS

Organism-specific databases

Human Protein Atlas

More...
HPAi
ENSG00000134588, Tissue enriched (testis)

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

<p>This subsection of the <a href="http://www.uniprot.org/help/interaction%5Fsection">'Interaction'</a> section provides information about the protein quaternary structure and interaction(s) with other proteins or protein complexes (with the exception of physiological receptor-ligand interactions which are annotated in the <a href="http://www.uniprot.org/help/function%5Fsection">'Function'</a> section).<p><a href='/help/subunit_structure' target='_top'>More...</a></p>Subunit structurei

Interacts with AR.

1 Publication

Protein-protein interaction databases

The Biological General Repository for Interaction Datasets (BioGRID)

More...
BioGRIDi
123764, 16 interactors

Protein interaction database and analysis system

More...
IntActi
Q9BXU7, 3 interactors

STRING: functional protein association networks

More...
STRINGi
9606.ENSP00000423390

Miscellaneous databases

RNAct, Protein-RNA interaction predictions for model organisms.

More...
RNActi
Q9BXU7, protein

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family%5Fand%5Fdomains%5Fsection">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini295 – 886USPAdd BLAST592

<p>This subsection of the 'Family and domains' section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Belongs to the peptidase C19 family.Curated

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
KOG1868, Eukaryota

Ensembl GeneTree

More...
GeneTreei
ENSGT00940000166393

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...
HOGENOMi
CLU_012557_0_0_1

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
Q9BXU7

Identification of Orthologs from Complete Genome Data

More...
OMAi
QNHLHLT

Database of Orthologous Groups

More...
OrthoDBi
129045at2759

Database for complete collections of gene phylogenies

More...
PhylomeDBi
Q9BXU7

TreeFam database of animal gene trees

More...
TreeFami
TF323032

Family and domain databases

Conserved Domains Database

More...
CDDi
cd13312, PH_USP37_like, 1 hit

Gene3D Structural and Functional Annotation of Protein Families

More...
Gene3Di
2.30.29.180, 1 hit

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR038765, Papain-like_cys_pep_sf
IPR001394, Peptidase_C19_UCH
IPR032069, USP37-like_PH
IPR038093, USP37-like_PH_sf
IPR018200, USP_CS
IPR028889, USP_dom

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF00443, UCH, 1 hit
PF16674, UCH_N, 1 hit

Superfamily database of structural and functional annotation

More...
SUPFAMi
SSF54001, SSF54001, 1 hit

PROSITE; a protein domain and family database

More...
PROSITEi
View protein in PROSITE
PS00972, USP_1, 1 hit
PS00973, USP_2, 1 hit
PS50235, USP_3, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

Q9BXU7-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MAALFLRGFV QIGNCKTGIS KSKEAFIEAV ERKKKDRLVL YFKSGKYSTF
60 70 80 90 100
RLSDNIQNVV LKSYRGNQNH LHLTLQNNNG LFIEGLSSTD AEQLKIFLDR
110 120 130 140 150
VHQNEVQPPV RPGKGGSVFS STTQKEINKT SFHKVDEKSS SKSFEIAKGS
160 170 180 190 200
GTGVLQRMPL LTSKLTLTCG ELSENQHKKR KRMLSSSSEM NEEFLKENNS
210 220 230 240 250
VEYKKSKADC SRCVSYNREK QLKLKELEEN KKLECESSCI MNATGNPYLD
260 270 280 290 300
DIGLLQALTE KMVLVFLLQQ GYSDGYTKWD KLKLFFELFP EKICHGLPNL
310 320 330 340 350
GNTCYMNAVL QSLLSIPSFA DDLLNQSFPW GKIPLNALTM CLARLLFFKD
360 370 380 390 400
TYNIEIKEML LLNLKKAISA AAEIFHGNAQ NDAHEFLAHC LDQLKDNMEK
410 420 430 440 450
LNTIWKPKSE FGEDNFPKQV FADDPDTSGF SCPVITNFEL ELLHSIACKA
460 470 480 490 500
CGQVILKTEL NNYLSINLPQ RIKAHPSSIQ STFDLFFGAE ELEYKCAKCE
510 520 530 540 550
HKTSVGVHSF SRLPRILIVH LKRYSLNEFC ALKKNDQEVI ISKYLKVSSH
560 570 580 590 600
CNEGTRPPLP LSEDGEITDF QLLKVIRKMT SGNISVSWPA TKESKDILAP
610 620 630 640 650
HIGSDKESEQ KKGQTVFKGA SRRQQQKYLG KNSKPNELES VYSGDRAFIE
660 670 680 690 700
KEPLAHLMTY LEDTSLCQFH KAGGKPASSP GTPLSKVDFQ TVPENPKRKK
710 720 730 740 750
YVKTSKFVAF DRIINPTKDL YEDKNIRIPE RFQKVSEQTQ QCDGMRICEQ
760 770 780 790 800
APQQALPQSF PKPGTQGHTK NLLRPTKLNL QKSNRNSLLA LGSNKNPRNK
810 820 830 840 850
DILDKIKSKA KETKRNDDKG DHTYRLISVV SHLGKTLKSG HYICDAYDFE
860 870 880 890 900
KQIWFTYDDM RVLGIQEAQM QEDRRCTGYI FFYMHNEIFE EMLKREENAQ
910
LNSKEVEETL QKE
Length:913
Mass (Da):104,047
Last modified:June 1, 2001 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:iBB70B09CDCBA3C48
GO

Natural variant

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Sequence' section describes natural variant(s) of the protein sequence.<p><a href='/help/variant' target='_top'>More...</a></p>Natural variantiVAR_063413123T → TT1 Publication1
Natural variantiVAR_063414165L → S1 PublicationCorresponds to variant dbSNP:rs61741870Ensembl.1
Natural variantiVAR_063415364L → F3 PublicationsCorresponds to variant dbSNP:rs35397110Ensembl.1
Natural variantiVAR_063416475H → Y2 PublicationsCorresponds to variant dbSNP:rs41299088Ensembl.1
Natural variantiVAR_063417517L → F1 PublicationCorresponds to variant dbSNP:rs1323347016Ensembl.1
Natural variantiVAR_063418579M → I1 PublicationCorresponds to variant dbSNP:rs138385391EnsemblClinVar.1

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

More...
GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
AF285593 mRNA Translation: AAK31972.1
Z81365 Genomic DNA No translation available.
BC069073 mRNA Translation: AAH69073.1
BC101190 mRNA Translation: AAI01191.1
BC101191 mRNA Translation: AAI01192.1

The Consensus CDS (CCDS) project

More...
CCDSi
CCDS14635.1

NCBI Reference Sequences

More...
RefSeqi
NP_114113.1, NM_031907.1
XP_016885381.1, XM_017029892.1

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...
Ensembli
ENST00000370832; ENSP00000359869; ENSG00000134588
ENST00000511190; ENSP00000423390; ENSG00000134588

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
83844

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
hsa:83844

UCSC genome browser

More...
UCSCi
uc010nrm.1, human

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF285593 mRNA Translation: AAK31972.1
Z81365 Genomic DNA No translation available.
BC069073 mRNA Translation: AAH69073.1
BC101190 mRNA Translation: AAI01191.1
BC101191 mRNA Translation: AAI01192.1
CCDSiCCDS14635.1
RefSeqiNP_114113.1, NM_031907.1
XP_016885381.1, XM_017029892.1

3D structure databases

Database of comparative protein structure models

More...
ModBasei
Search...

SWISS-MODEL Interactive Workspace

More...
SWISS-MODEL-Workspacei
Submit a new modelling project...

Protein-protein interaction databases

BioGRIDi123764, 16 interactors
IntActiQ9BXU7, 3 interactors
STRINGi9606.ENSP00000423390

Protein family/group databases

MEROPSiC19.046

PTM databases

iPTMnetiQ9BXU7
PhosphoSitePlusiQ9BXU7

Genetic variation databases

BioMutaiUSP26
DMDMi18202739

Proteomic databases

PaxDbiQ9BXU7
PeptideAtlasiQ9BXU7
PRIDEiQ9BXU7
ProteomicsDBi79521

Protocols and materials databases

Antibodypedia a portal for validated antibodies

More...
Antibodypediai
30257, 104 antibodies

Genome annotation databases

EnsembliENST00000370832; ENSP00000359869; ENSG00000134588
ENST00000511190; ENSP00000423390; ENSG00000134588
GeneIDi83844
KEGGihsa:83844
UCSCiuc010nrm.1, human

Organism-specific databases

Comparative Toxicogenomics Database

More...
CTDi
83844
DisGeNETi83844

GeneCards: human genes, protein and diseases

More...
GeneCardsi
USP26
HGNCiHGNC:13485, USP26
HPAiENSG00000134588, Tissue enriched (testis)
MIMi300309, gene
neXtProtiNX_Q9BXU7
OpenTargetsiENSG00000134588
PharmGKBiPA37782
VEuPathDBiHostDB:ENSG00000134588.12

GenAtlas: human gene database

More...
GenAtlasi
Search...

Phylogenomic databases

eggNOGiKOG1868, Eukaryota
GeneTreeiENSGT00940000166393
HOGENOMiCLU_012557_0_0_1
InParanoidiQ9BXU7
OMAiQNHLHLT
OrthoDBi129045at2759
PhylomeDBiQ9BXU7
TreeFamiTF323032

Enzyme and pathway databases

PathwayCommonsiQ9BXU7
ReactomeiR-HSA-5689880, Ub-specific processing proteases

Miscellaneous databases

BioGRID ORCS database of CRISPR phenotype screens

More...
BioGRID-ORCSi
83844, 7 hits in 501 CRISPR screens

Database of phenotypes from RNA interference screens in Drosophila and Homo sapiens

More...
GenomeRNAii
83844
PharosiQ9BXU7, Tbio

Protein Ontology

More...
PROi
PR:Q9BXU7
RNActiQ9BXU7, protein

The Stanford Online Universal Resource for Clones and ESTs

More...
SOURCEi
Search...

Gene expression databases

BgeeiENSG00000134588, Expressed in muscle tissue and 25 other tissues
GenevisibleiQ9BXU7, HS

Family and domain databases

CDDicd13312, PH_USP37_like, 1 hit
Gene3Di2.30.29.180, 1 hit
InterProiView protein in InterPro
IPR038765, Papain-like_cys_pep_sf
IPR001394, Peptidase_C19_UCH
IPR032069, USP37-like_PH
IPR038093, USP37-like_PH_sf
IPR018200, USP_CS
IPR028889, USP_dom
PfamiView protein in Pfam
PF00443, UCH, 1 hit
PF16674, UCH_N, 1 hit
SUPFAMiSSF54001, SSF54001, 1 hit
PROSITEiView protein in PROSITE
PS00972, USP_1, 1 hit
PS00973, USP_2, 1 hit
PS50235, USP_3, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

More...
ProtoNeti
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiUBP26_HUMAN
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q9BXU7
Secondary accession number(s): B9WRT6, Q5H9H4
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: September 26, 2001
Last sequence update: June 1, 2001
Last modified: February 10, 2021
This is version 149 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Reference proteome

Documents

  1. Human chromosome X
    Human chromosome X: entries, gene names and cross-references to MIM
  2. Human entries with genetic variants
    List of human entries with genetic variants
  3. Human variants curated from literature reports
    Index of human variants curated from literature reports
  4. MIM cross-references
    Online Mendelian Inheritance in Man (MIM) cross-references in UniProtKB/Swiss-Prot
  5. SIMILARITY comments
    Index of protein domains and families
  6. Peptidase families
    Classification of peptidase families and list of entries
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