Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
The new UniProt website is here! Take me to UniProt BETA

UniProtKB - Q9BXJ1 (C1QT1_HUMAN)

Entry version 173 (25 May 2022)
Sequence version 1 (01 Jun 2001)
Previous versions | rss
Add a publicationFeedback
Protein

Complement C1q tumor necrosis factor-related protein 1

Gene

C1QTNF1

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score:

Annotation score:5 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

Complete GO annotation on QuickGO ...

GO - Biological processi

Complete GO annotation on QuickGO ...

Enzyme and pathway databases

Pathway Commons web resource for biological pathway data

More...PathwayCommonsi		Q9BXJ1

SignaLink: a signaling pathway resource with multi-layered regulatory networks

More...SignaLinki		Q9BXJ1

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Complement C1q tumor necrosis factor-related protein 1
Alternative name(s):
G protein-coupled receptor-interacting protein
Short name:
GIP
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:C1QTNF1
Synonyms:CTRP1
ORF Names:UNQ310/PRO353
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiHomo sapiens (Human)
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri9606 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Primates › Haplorrhini › Catarrhini › Hominidae › Homo
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000005640 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 17

Organism-specific databases

Human Gene Nomenclature Database

More...HGNCi		HGNC:14324, C1QTNF1

Online Mendelian Inheritance in Man (OMIM)

More...MIMi		610365, gene

neXtProt; the human protein knowledge platform

More...neXtProti		NX_Q9BXJ1

Eukaryotic Pathogen, Vector and Host Database Resources

More...VEuPathDBi		HostDB:ENSG00000173918

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywords - Cellular componenti

Secreted

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

Organism-specific databases

DisGeNET

More...DisGeNETi		114897

Open Targets

More...OpenTargetsi		ENSG00000173918

The Pharmacogenetics and Pharmacogenomics Knowledge Base

More...PharmGKBi		PA25628

Miscellaneous databases

Pharos NIH Druggable Genome Knowledgebase

More...Pharosi		Q9BXJ1, Tbio

Genetic variation databases

BioMuta curated single-nucleotide variation and disease association database

More...BioMutai		C1QTNF1

Domain mapping of disease mutations (DMDM)

More...DMDMi		20177862

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'PTM / Processing' section denotes the presence of an N-terminal signal peptide.<p><a href='/help/signal' target='_top'>More...</a></p>Signal peptidei1 – 25Sequence analysisAdd BLAST25
<p>This subsection of the 'PTM / Processing' section describes the extent of a polypeptide chain in the mature protein following processing or proteolytic cleavage.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_000000352926 – 281Complement C1q tumor necrosis factor-related protein 1Add BLAST256

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/ptm%5Fprocessing%5Fsection">PTM / Processing</a> section specifies the position and type of each covalently attached glycan group (mono-, di-, or polysaccharide).<p><a href='/help/carbohyd' target='_top'>More...</a></p>Glycosylationi93N-linked (GlcNAc...) asparagineSequence analysis1

Keywords - PTMi

Glycoprotein

Proteomic databases

MassIVE - Mass Spectrometry Interactive Virtual Environment

More...MassIVEi		Q9BXJ1

PaxDb, a database of protein abundance averages across all three domains of life

More...PaxDbi		Q9BXJ1

PeptideAtlas

More...PeptideAtlasi		Q9BXJ1

PRoteomics IDEntifications database

More...PRIDEi		Q9BXJ1

ProteomicsDB: a multi-organism proteome resource

More...ProteomicsDBi		67870
79433 [Q9BXJ1-1]

PTM databases

GlyGen: Computational and Informatics Resources for Glycoscience

More...GlyGeni		Q9BXJ1, 1 site

iPTMnet integrated resource for PTMs in systems biology context

More...iPTMneti		Q9BXJ1

Comprehensive resource for the study of protein post-translational modifications (PTMs) in human, mouse and rat.

More...PhosphoSitePlusi		Q9BXJ1

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...Bgeei		ENSG00000173918, Expressed in left coronary artery and 195 other tissues

ExpressionAtlas, Differential and Baseline Expression

More...ExpressionAtlasi		Q9BXJ1, baseline and differential

Genevisible search portal to normalized and curated expression data from Genevestigator

More...Genevisiblei		Q9BXJ1, HS

Organism-specific databases

Human Protein Atlas

More...HPAi		ENSG00000173918, Tissue enhanced (adipose tissue, heart muscle)

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

<p>This subsection of the '<a href="http://www.uniprot.org/help/interaction%5Fsection">Interaction</a>' section provides information about binary protein-protein interactions. The data presented in this section are a quality-filtered subset of binary interactions automatically derived from the <a href="https://www.ebi.ac.uk/intact/">IntAct database</a>. It is updated at every <a href="http://www.uniprot.org/help/synchronization">UniProt release</a>.<p><a href='/help/binary_interactions' target='_top'>More...</a></p>Binary interactionsi

Hide details

GO - Molecular functioni

Complete GO annotation on QuickGO ...

Protein-protein interaction databases

The Biological General Repository for Interaction Datasets (BioGRID)

More...BioGRIDi		125388, 48 interactors

Protein interaction database and analysis system

More...IntActi		Q9BXJ1, 9 interactors

STRING: functional protein association networks

More...STRINGi		9606.ENSP00000340864

Miscellaneous databases

RNAct, Protein-RNA interaction predictions for model organisms.

More...RNActi		Q9BXJ1, protein

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

AlphaFold Protein Structure Database

More...AlphaFoldDBi		Q9BXJ1

SWISS-MODEL Repository - a database of annotated 3D protein structure models

More...SMRi		Q9BXJ1

Database of comparative protein structure models

More...ModBasei		Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family%5Fand%5Fdomains%5Fsection">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini99 – 140Collagen-likeAdd BLAST42
Domaini141 – 281C1qPROSITE-ProRule annotationAdd BLAST141

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes a region of interest that cannot be described in other subsections.<p><a href='/help/region' target='_top'>More...</a></p>Regioni34 – 68DisorderedSequence analysisAdd BLAST35
Regioni100 – 138DisorderedSequence analysisAdd BLAST39

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes the position of regions of compositional bias within the protein and the particular type of amino acids that are over-represented within those regions.<p><a href='/help/compbias' target='_top'>More...</a></p>Compositional biasi42 – 62Basic and acidic residuesSequence analysisAdd BLAST21

Keywords - Domaini

Collagen, Signal

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...eggNOGi		ENOG502QT5D, Eukaryota

Ensembl GeneTree

More...GeneTreei		ENSGT00940000161333

InParanoid: Eukaryotic Ortholog Groups

More...InParanoidi		Q9BXJ1

Identification of Orthologs from Complete Genome Data

More...OMAi		QCFRCCD

Database of Orthologous Groups

More...OrthoDBi		1136568at2759

Database for complete collections of gene phylogenies

More...PhylomeDBi		Q9BXJ1

TreeFam database of animal gene trees

More...TreeFami		TF329591

Family and domain databases

Gene3D Structural and Functional Annotation of Protein Families

More...Gene3Di		2.60.120.40, 1 hit

Integrated resource of protein families, domains and functional sites

More...InterProi		View protein in InterPro
IPR001073, C1q_dom
IPR008160, Collagen
IPR008983, Tumour_necrosis_fac-like_dom

Pfam protein domain database

More...Pfami		View protein in Pfam
PF00386, C1q, 1 hit
PF01391, Collagen, 1 hit

Protein Motif fingerprint database; a protein domain database

More...PRINTSi		PR00007, COMPLEMNTC1Q

Simple Modular Architecture Research Tool; a protein domain database

More...SMARTi		View protein in SMART
SM00110, C1Q, 1 hit

Superfamily database of structural and functional annotation

More...SUPFAMi		SSF49842, SSF49842, 1 hit

PROSITE; a protein domain and family database

More...PROSITEi		View protein in PROSITE
PS50871, C1Q, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequences (2+)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is in its mature form or if it represents the precursor.<p><a href='/help/sequence_processing' target='_top'>More...</a></p>Sequence processingi: The displayed sequence is further processed into a mature form.

This entry describes 2 <p>This subsection of the 'Sequence' section lists the alternative protein sequences (isoforms) that can be generated from the same gene by a single or by the combination of up to four biological events (alternative promoter usage, alternative splicing, alternative initiation and ribosomal frameshifting). Additionally, this section gives relevant information on each alternative protein isoform.<p><a href='/help/alternative_products' target='_top'>More...</a></p> isoformsi produced by alternative splicing. AlignAdd to basket

This entry has 2 described isoforms and 1 potential isoform that is computationally mapped.Show allAlign All

Isoform 1 (identifier: Q9BXJ1-1) [UniParc]FASTAAdd to basket

This isoform has been chosen as the <p><strong>What is the canonical sequence?</strong><p><a href='/help/canonical_and_isoforms' target='_top'>More...</a></p>canonicali sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

« Hide
        10         20         30         40         50
MGSRGQGLLL AYCLLLAFAS GLVLSRVPHV QGEQQEWEGT EELPSPPDHA 
        60         70         80         90        100
ERAEEQHEKY RPSQDQGLPA SRCLRCCDPG TSMYPATAVP QINITILKGE 
       110        120        130        140        150
KGDRGDRGLQ GKYGKTGSAG ARGHTGPKGQ KGSMGAPGER CKSHYAAFSV 
       160        170        180        190        200
GRKKPMHSNH YYQTVIFDTE FVNLYDHFNM FTGKFYCYVP GLYFFSLNVH 
       210        220        230        240        250
TWNQKETYLH IMKNEEEVVI LFAQVGDRSI MQSQSLMLEL REQDQVWVRL 
       260        270        280 
YKGERENAIF SEELDTYITF SGYLVKHATE P
Length:281
Mass (Da):31,743
Last modified:June 1, 2001 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i49E248CB88ACFB7C
GO
Isoform 2 (identifier: Q9BXJ1-2) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     1-1: M → MMSATGPGRKM

Show »
Length:291
Mass (Da):32,760
Checksum:i96A76F774212AB88
GO

<p>In eukaryotic reference proteomes, unreviewed entries that are likely to belong to the same gene are computationally mapped, based on gene identifiers from Ensembl, EnsemblGenomes and model organism databases.<p><a href='/help/gene_centric_isoform_mapping' target='_top'>More...</a></p>Computationally mapped potential isoform sequencesi

There is 1 potential isoform mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
A0A0C4DFP7A0A0C4DFP7_HUMAN
Complement C1q tumor necrosis facto...
C1QTNF1
199Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>

<p>This subsection of the 'Sequence' section reports difference(s) between the protein sequence shown in the UniProtKB entry and other available protein sequences derived from the same gene.<p><a href='/help/sequence_caution' target='_top'>More...</a></p>Sequence cautioni

The sequence AAG44303 differs from that shown. Reason: Erroneous initiation.Curated
The sequence CAC20425 differs from that shown. Reason: Erroneous initiation.Curated

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Sequence' section reports difference(s) between the canonical sequence (displayed by default in the entry) and the different sequence submissions merged in the entry. These various submissions may originate from different sequencing projects, different types of experiments, or different biological samples. Sequence conflicts are usually of unknown origin.<p><a href='/help/conflict' target='_top'>More...</a></p>Sequence conflicti22L → P in CAC20425 (Ref. 1) Curated1
Sequence conflicti22L → P in AAG44303 (Ref. 1) Curated1

Natural variant

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Sequence' section describes natural variant(s) of the protein sequence.<p><a href='/help/variant' target='_top'>More...</a></p>Natural variantiVAR_068885241R → Q1 PublicationCorresponds to variant dbSNP:rs35035542Ensembl.1

Alternative sequence

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Sequence' section describes the sequence of naturally occurring alternative protein isoform(s). The changes in the amino acid sequence may be due to alternative splicing, alternative promoter usage, alternative initiation, or ribosomal frameshifting.<p><a href='/help/var_seq' target='_top'>More...</a></p>Alternative sequenceiVSP_0555701M → MMSATGPGRKM in isoform 2. 1 Publication1

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...EMBLi

GenBank nucleotide sequence database

More...GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...DDBJi
Links Updated
AJ272138 mRNA Translation: CAC20425.1 Different initiation.
AF232905 mRNA Translation: AAG44303.1 Different initiation.
AF329840 mRNA Translation: AAK17964.1
AY358424 mRNA Translation: AAQ88790.1
AK055541 mRNA Translation: BAB70947.1
AK075175 mRNA Translation: BAC11451.1
AK172767 mRNA Translation: BAD18750.1
AC073624 Genomic DNA No translation available.
BC021553 mRNA Translation: AAH21553.1

The Consensus CDS (CCDS) project

More...CCDSi		CCDS11761.1 [Q9BXJ1-1]

NCBI Reference Sequences

More...RefSeqi		NP_112230.1, NM_030968.4 [Q9BXJ1-1]
NP_699203.1, NM_153372.2 [Q9BXJ1-1]
NP_940995.1, NM_198593.4 [Q9BXJ1-1]
NP_940996.1, NM_198594.3
XP_006721729.1, XM_006721666.1 [Q9BXJ1-2]
XP_016879615.1, XM_017024126.1

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...Ensembli		ENST00000339142.6; ENSP00000340864.2; ENSG00000173918.15
ENST00000354124.7; ENSP00000343230.4; ENSG00000173918.15
ENST00000392445.6; ENSP00000376240.2; ENSG00000173918.15
ENST00000579760.6; ENSP00000463922.1; ENSG00000173918.15
ENST00000580454.5; ENSP00000462990.1; ENSG00000173918.15
ENST00000580474.1; ENSP00000463108.1; ENSG00000173918.15
ENST00000581774.5; ENSP00000462481.2; ENSG00000173918.15
ENST00000583904.5; ENSP00000463008.1; ENSG00000173918.15

Database of genes from NCBI RefSeq genomes

More...GeneIDi		114897

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...KEGGi		hsa:114897

Matched Annotation from NCBI and EMBL-EBI (MANE) - Phase one

More...MANE-Selecti		ENST00000579760.6; ENSP00000463922.1; NM_030968.5; NP_112230.1

UCSC genome browser

More...UCSCi		uc002jwp.5, human [Q9BXJ1-1]

Keywords - Coding sequence diversityi

Alternative splicing

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AJ272138 mRNA Translation: CAC20425.1 Different initiation.
AF232905 mRNA Translation: AAG44303.1 Different initiation.
AF329840 mRNA Translation: AAK17964.1
AY358424 mRNA Translation: AAQ88790.1
AK055541 mRNA Translation: BAB70947.1
AK075175 mRNA Translation: BAC11451.1
AK172767 mRNA Translation: BAD18750.1
AC073624 Genomic DNA No translation available.
BC021553 mRNA Translation: AAH21553.1
CCDSiCCDS11761.1 [Q9BXJ1-1]
RefSeqiNP_112230.1, NM_030968.4 [Q9BXJ1-1]
NP_699203.1, NM_153372.2 [Q9BXJ1-1]
NP_940995.1, NM_198593.4 [Q9BXJ1-1]
NP_940996.1, NM_198594.3
XP_006721729.1, XM_006721666.1 [Q9BXJ1-2]
XP_016879615.1, XM_017024126.1

3D structure databases

AlphaFoldDBiQ9BXJ1
SMRiQ9BXJ1
ModBaseiSearch...

Protein-protein interaction databases

BioGRIDi125388, 48 interactors
IntActiQ9BXJ1, 9 interactors
STRINGi9606.ENSP00000340864

PTM databases

GlyGeniQ9BXJ1, 1 site
iPTMnetiQ9BXJ1
PhosphoSitePlusiQ9BXJ1

Genetic variation databases

BioMutaiC1QTNF1
DMDMi20177862

Proteomic databases

MassIVEiQ9BXJ1
PaxDbiQ9BXJ1
PeptideAtlasiQ9BXJ1
PRIDEiQ9BXJ1
ProteomicsDBi67870
79433 [Q9BXJ1-1]

Protocols and materials databases

Antibodypedia a portal for validated antibodies

More...Antibodypediai		19749, 283 antibodies from 34 providers

The DNASU plasmid repository

More...DNASUi		114897

Genome annotation databases

EnsembliENST00000339142.6; ENSP00000340864.2; ENSG00000173918.15
ENST00000354124.7; ENSP00000343230.4; ENSG00000173918.15
ENST00000392445.6; ENSP00000376240.2; ENSG00000173918.15
ENST00000579760.6; ENSP00000463922.1; ENSG00000173918.15
ENST00000580454.5; ENSP00000462990.1; ENSG00000173918.15
ENST00000580474.1; ENSP00000463108.1; ENSG00000173918.15
ENST00000581774.5; ENSP00000462481.2; ENSG00000173918.15
ENST00000583904.5; ENSP00000463008.1; ENSG00000173918.15
GeneIDi114897
KEGGihsa:114897
MANE-SelectiENST00000579760.6; ENSP00000463922.1; NM_030968.5; NP_112230.1
UCSCiuc002jwp.5, human [Q9BXJ1-1]

Organism-specific databases

Comparative Toxicogenomics Database

More...CTDi		114897
DisGeNETi114897

GeneCards: human genes, protein and diseases

More...GeneCardsi		C1QTNF1
HGNCiHGNC:14324, C1QTNF1
HPAiENSG00000173918, Tissue enhanced (adipose tissue, heart muscle)
MIMi610365, gene
neXtProtiNX_Q9BXJ1
OpenTargetsiENSG00000173918
PharmGKBiPA25628
VEuPathDBiHostDB:ENSG00000173918

GenAtlas: human gene database

More...GenAtlasi		Search...

Phylogenomic databases

eggNOGiENOG502QT5D, Eukaryota
GeneTreeiENSGT00940000161333
InParanoidiQ9BXJ1
OMAiQCFRCCD
OrthoDBi1136568at2759
PhylomeDBiQ9BXJ1
TreeFamiTF329591

Enzyme and pathway databases

PathwayCommonsiQ9BXJ1
SignaLinkiQ9BXJ1

Miscellaneous databases

BioGRID ORCS database of CRISPR phenotype screens

More...BioGRID-ORCSi		114897, 14 hits in 1065 CRISPR screens

ChiTaRS: a database of human, mouse and fruit fly chimeric transcripts and RNA-sequencing data

More...ChiTaRSi		C1QTNF1, human

The Gene Wiki collection of pages on human genes and proteins

More...GeneWikii		C1QTNF1

Database of phenotypes from RNA interference screens in Drosophila and Homo sapiens

More...GenomeRNAii		114897
PharosiQ9BXJ1, Tbio

Protein Ontology

More...PROi		PR:Q9BXJ1
RNActiQ9BXJ1, protein

The Stanford Online Universal Resource for Clones and ESTs

More...SOURCEi		Search...

Gene expression databases

BgeeiENSG00000173918, Expressed in left coronary artery and 195 other tissues
ExpressionAtlasiQ9BXJ1, baseline and differential
GenevisibleiQ9BXJ1, HS

Family and domain databases

Gene3Di2.60.120.40, 1 hit
InterProiView protein in InterPro
IPR001073, C1q_dom
IPR008160, Collagen
IPR008983, Tumour_necrosis_fac-like_dom
PfamiView protein in Pfam
PF00386, C1q, 1 hit
PF01391, Collagen, 1 hit
PRINTSiPR00007, COMPLEMNTC1Q
SMARTiView protein in SMART
SM00110, C1Q, 1 hit
SUPFAMiSSF49842, SSF49842, 1 hit
PROSITEiView protein in PROSITE
PS50871, C1Q, 1 hit

MobiDB: a database of protein disorder and mobility annotations

More...MobiDBi		Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiC1QT1_HUMAN
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q9BXJ1
Secondary accession number(s): Q6ZMH6, Q96NF2, Q9GZR4
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: April 16, 2002
Last sequence update: June 1, 2001
Last modified: May 25, 2022
This is version 173 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Reference proteome

Documents

  1. Human chromosome 17
    Human chromosome 17: entries, gene names and cross-references to MIM
  2. Human entries with genetic variants
    List of human entries with genetic variants
  3. Human variants curated from literature reports
    Index of human variants curated from literature reports
  4. MIM cross-references
    Online Mendelian Inheritance in Man (MIM) cross-references in UniProtKB/Swiss-Prot
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

We'd like to inform you that we have updated our Privacy Notice to comply with Europe’s new General Data Protection Regulation (GDPR) that applies since 25 May 2018.

Do not show this banner again